-
1
-
-
0035976638
-
Nuclear receptors and lipid physiology: Opening the X-files
-
Chawla, A. et al. (2001) Nuclear receptors and lipid physiology: opening the X-files. Science 294, 1866-1870
-
(2001)
Science
, vol.294
, pp. 1866-1870
-
-
Chawla, A.1
-
2
-
-
0033305213
-
Peroxisome proliferator-activated receptors: Nuclear control of metabolism
-
Desvergne, B. and Wahli, W. (1999) Peroxisome proliferator-activated receptors: nuclear control of metabolism. Endocr. Rev. 20, 649-688
-
(1999)
Endocr. Rev.
, vol.20
, pp. 649-688
-
-
Desvergne, B.1
Wahli, W.2
-
3
-
-
0035786906
-
Peroxisome proliferator-activated receptors: From genes to physiology
-
Kliewer, S.A. et al. (2001) Peroxisome proliferator-activated receptors: from genes to physiology. Recent Prog. Horm. Res. 56, 239-263
-
(2001)
Recent Prog. Horm. Res.
, vol.56
, pp. 239-263
-
-
Kliewer, S.A.1
-
4
-
-
0027278522
-
Positive regulation of the peroxisomal P-oxidation pathway by fatty acids through activation of peroxisome proliferator-activated receptors (PPAR)
-
Dreyer, C. et al. (1993) Positive regulation of the peroxisomal P-oxidation pathway by fatty acids through activation of peroxisome proliferator-activated receptors (PPAR). Biol. Cell 77, 67-76
-
(1993)
Biol. Cell
, vol.77
, pp. 67-76
-
-
Dreyer, C.1
-
5
-
-
0030952937
-
Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors α and δ
-
Forman, B.M. et al. (1997) Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors α and δ. Proc. Natl. Acad. Sci. U. S. A. 94, 4312-4317
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 4312-4317
-
-
Forman, B.M.1
-
6
-
-
0006132932
-
Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors α and γ
-
Kliewer, S.A. et al. (1997) Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors α and γ. Proc. Natl. Acad. Sci. U. S.A. 94, 4318-4323
-
(1997)
Proc. Natl. Acad. Sci. U. S.A.
, vol.94
, pp. 4318-4323
-
-
Kliewer, S.A.1
-
7
-
-
0030985318
-
Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay
-
Krey, G. et al. (1997) Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay. Mol. Endocrinol. 11, 779-791
-
(1997)
Mol. Endocrinol.
, vol.11
, pp. 779-791
-
-
Krey, G.1
-
8
-
-
0028972025
-
15-Deoxy-δ12,14-prostaglandin J2 is a ligand for the adipocyte determination factor PPARγ
-
Forman, B.M. et al. (1995) 15-Deoxy-δ12,14-prostaglandin J2 is a ligand for the adipocyte determination factor PPARγ. Cell 83, 803-812
-
(1995)
Cell
, vol.83
, pp. 803-812
-
-
Forman, B.M.1
-
9
-
-
0028972026
-
A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation
-
Kliewer, S.A. et al. (1995)A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation. Cell 83, 813-819
-
(1995)
Cell
, vol.83
, pp. 813-819
-
-
Kliewer, S.A.1
-
10
-
-
0029016829
-
An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor γ(PPARγ)
-
Lehmann, J.M. et al. (1995)An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor γ(PPARγ). J. Biol. Chem. 270, 12953-12956
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 12953-12956
-
-
Lehmann, J.M.1
-
11
-
-
0033213637
-
PPARγ is required for placental, cardiac, and adipose tissue development
-
Barak, Y. et al. (1999) PPARγ is required for placental, cardiac, and adipose tissue development. Mol. Cell 4, 585-595
-
(1999)
Mol. Cell
, vol.4
, pp. 585-595
-
-
Barak, Y.1
-
12
-
-
0033212964
-
PPARγ mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance
-
Kubota, N. et al. (1999) PPARγ mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance. Mol. Cell 4, 597-609
-
(1999)
Mol. Cell
, vol.4
, pp. 597-609
-
-
Kubota, N.1
-
13
-
-
0033213631
-
PPARγ is required for the differentiation of adipose tissue in vivo and in vitro
-
Rosen, E.D. et al. (1999) PPARγ is required for the differentiation of adipose tissue in vivo and in vitro. Mol. Cell 4, 611-617
-
(1999)
Mol. Cell
, vol.4
, pp. 611-617
-
-
Rosen, E.D.1
-
14
-
-
0033625677
-
Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptorβ (δ)
-
Peters, J.M. et al. (2000) Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptorβ (δ). Mol. Cell. Biol. 20, 5119-5128
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 5119-5128
-
-
Peters, J.M.1
-
15
-
-
0035921419
-
Impaired skin wound healing in peroxisome proliferator-activated receptor (PPAR) α- and PPARβ-mutant mice
-
Michalik, L. et al. (2001) Impaired skin wound healing in peroxisome proliferator-activated receptor (PPAR) α- and PPARβ-mutant mice. J. Cell Biol. 154, 799-814
-
(2001)
J. Cell Biol.
, vol.154
, pp. 799-814
-
-
Michalik, L.1
-
16
-
-
0035942162
-
A selective peroxisome proliferator-activated receptor δ agonist promotes reverse cholesterol transport
-
Oliver, W.R., Jr et al. (2001) A selective peroxisome proliferator-activated receptor δ agonist promotes reverse cholesterol transport. Proc. Natl. Acad. Sci. U. S. A. 98, 5306-5311
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 5306-5311
-
-
Oliver W.R., Jr.1
-
17
-
-
0032540012
-
PPARγ promotes monocyte/macrophage differentiation and uptake of oxidized LDL
-
Tontonoz, P. et al. (1998) PPARγ promotes monocyte/macrophage differentiation and uptake of oxidized LDL. Cell 93, 241-252
-
(1998)
Cell
, vol.93
, pp. 241-252
-
-
Tontonoz, P.1
-
18
-
-
0032540325
-
Oxidized LDL regulates macrophage gene expression through ligand activation of PPARγ
-
Nagy, L. et al. (1998) Oxidized LDL regulates macrophage gene expression through ligand activation of PPARγ. Cell 93, 229-240
-
(1998)
Cell
, vol.93
, pp. 229-240
-
-
Nagy, L.1
-
19
-
-
0031886864
-
The peroxisome proliferator-activated receptor γ is a negative regulator of macrophage activation
-
Ricote, M. et al. (1998) The peroxisome proliferator-activated receptor γ is a negative regulator of macrophage activation. Nature 391, 79-82
-
(1998)
Nature
, vol.391
, pp. 79-82
-
-
Ricote, M.1
-
20
-
-
0031888958
-
PPARγ agonists inhibit production of monocyte inflammatory cytokines
-
Jiang, C. et al. (1998) PPARγ agonists inhibit production of monocyte inflammatory cytokines. Nature 391, 82-86
-
(1998)
Nature
, vol.391
, pp. 82-86
-
-
Jiang, C.1
-
21
-
-
0031898610
-
PPARγ adipogenic regulator and thiazolidinedione receptor
-
Spiegelman, B.M. (1998) PPARγ adipogenic regulator and thiazolidinedione receptor. Diabetes 47, 507-514
-
(1998)
Diabetes
, vol.47
, pp. 507-514
-
-
Spiegelman, B.M.1
-
22
-
-
0034992643
-
Regulation of lineage commitment during lymphocyte development
-
Staal, F.J. and Clevers, H.C. (2001) Regulation of lineage commitment during lymphocyte development. Int. Rev. Immunol. 20, 45-64
-
(2001)
Int. Rev. Immunol.
, vol.20
, pp. 45-64
-
-
Staal, F.J.1
Clevers, H.C.2
-
23
-
-
0034982567
-
Transcription factors that regulate growth and differentiation of myeloid cells
-
Nagamura-Inoue, T. et al. (2001) Transcription factors that regulate growth and differentiation of myeloid cells. Int. Rev. Immunol. 20, 83-105
-
(2001)
Int. Rev. Immunol.
, vol.20
, pp. 83-105
-
-
Nagamura-Inoue, T.1
-
24
-
-
0035969097
-
Transcriptional regulation in acute promyelocytic leukemia
-
Lin, R.J. et al. (2001) Transcriptional regulation in acute promyelocytic leukemia. Oncogene 20, 7204-7215
-
(2001)
Oncogene
, vol.20
, pp. 7204-7215
-
-
Lin, R.J.1
-
25
-
-
0035132330
-
PPARγ-dependent and -independent effects on macrophage-gene expression in lipid metabolism and inflammation
-
Chawla, A. et al. (2001) PPARγ-dependent and -independent effects on macrophage-gene expression in lipid metabolism and inflammation. Nat. Med. 7, 48-52
-
(2001)
Nat. Med.
, vol.7
, pp. 48-52
-
-
Chawla, A.1
-
26
-
-
0035139016
-
The role of PPARγ in macrophage differentiation and cholesterol uptake
-
Moore, K.J. et al. (2001) The role of PPARγ in macrophage differentiation and cholesterol uptake. Nat. Med. 7, 41-47
-
(2001)
Nat. Med.
, vol.7
, pp. 41-47
-
-
Moore, K.J.1
-
27
-
-
0034648768
-
Atherosclerosis
-
Lusis, A.J. (2000) Atherosclerosis. Nature 407, 233-241
-
(2000)
Nature
, vol.407
, pp. 233-241
-
-
Lusis, A.J.1
-
28
-
-
0035936802
-
Atherosclerosis. The road ahead
-
Glass, C.K. and Witztum, J.L. (2001) Atherosclerosis. The road ahead. Cell 104, 503-516
-
(2001)
Cell
, vol.104
, pp. 503-516
-
-
Glass, C.K.1
Witztum, J.L.2
-
29
-
-
0034769830
-
Peroxisome proliferator-activated receptors in endothelial cell biology
-
Plutzky, J. (2001) Peroxisome proliferator-activated receptors in endothelial cell biology. Curr. Opin. Lipidol. 12, 511-518
-
(2001)
Curr. Opin. Lipidol.
, vol.12
, pp. 511-518
-
-
Plutzky, J.1
-
30
-
-
0001297403
-
Activation of human T lymphocytes is inhibited by peroxisome proliferator-activated receptor γ (PPARγ) agonists. PPARγ co-association with transcription factor NFAT
-
Yang, X.Y. et al. (2000) Activation of human T lymphocytes is inhibited by peroxisome proliferator-activated receptor γ (PPARγ) agonists. PPARγ co-association with transcription factor NFAT. J. Biol. Chem. 275, 4541-4544
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 4541-4544
-
-
Yang, X.Y.1
-
31
-
-
0034650330
-
Activation of peroxisome proliferator-activated receptor γ does not inhibit IL-6 or TNF-α responses of macrophages to lipopolysaccharide in vitro or in vivo
-
Thieringer, R. et al. (2000) Activation of peroxisome proliferator-activated receptor γ does not inhibit IL-6 or TNF-α responses of macrophages to lipopolysaccharide in vitro or in vivo. J. Immunol. 164, 1046-1054
-
(2000)
J. Immunol.
, vol.164
, pp. 1046-1054
-
-
Thieringer, R.1
-
32
-
-
0033622133
-
Inhibition of IκB kinase and IκB phosphorylation by 15-deoxy- δ(12,14)-prostaglandin J(2) in activated murine macrophages
-
Castrillo, A. et al. (2000) Inhibition of IκB kinase and IκB phosphorylation by 15-deoxy- δ(12,14)-prostaglandin J(2) in activated murine macrophages. Mol. Cell. Biol. 20, 1692-1698
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 1692-1698
-
-
Castrillo, A.1
-
33
-
-
0034610759
-
Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IκB kinase
-
Rossi et al. (2000)Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IκB kinase. Nature 403, 103-108
-
(2000)
Nature
, vol.403
, pp. 103-108
-
-
Rossi1
-
34
-
-
0034121698
-
Peroxisome proliferator-activated receptor γ-dependent repression of the inducible nitric oxide synthase gene
-
Li, M. et al. (2000) Peroxisome proliferator-activated receptor γ-dependent repression of the inducible nitric oxide synthase gene. Mol. Cell. Biol. 20, 4699-4707
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 4699-4707
-
-
Li, M.1
-
35
-
-
0031324353
-
The multiple roles of macrophage scavenger receptors (MSR) in vivo: Resistance to atherosclerosis and insusceptibility to infection in Msr-knockout mice
-
Suzuki, H. et al. (1997) The multiple roles of macrophage scavenger receptors (MSR) in vivo: resistance to atherosclerosis and insusceptibility to infection in Msr-knockout mice. J. Atheroscler. Thromb 4, 1-11
-
(1997)
J. Atheroscler. Thromb.
, vol.4
, pp. 1-11
-
-
Suzuki, H.1
-
36
-
-
0034101821
-
Targeted disruption of the class B scavenger receptor CD36 protects against atherosclerotic lesion development in mice
-
Febbraio, M. et al. (2000) Targeted disruption of the class B scavenger receptor CD36 protects against atherosclerotic lesion development in mice. J. Clin. Invest. 105, 1049-1056
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 1049-1056
-
-
Febbraio, M.1
-
37
-
-
0035138625
-
PPARα and PPARγ activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway
-
Chinetti, G. et al. (2001) PPARα and PPARγ activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway. Nat. Med. 7, 53-58
-
(2001)
Nat. Med.
, vol.7
, pp. 53-58
-
-
Chinetti, G.1
-
38
-
-
17744376173
-
A PPARγ-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis
-
Chawla, A. et al. (2001) A PPARγ-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis. Mol. Cell 7, 161-171
-
(2001)
Mol. Cell
, vol.7
, pp. 161-171
-
-
Chawla, A.1
-
39
-
-
0034284918
-
Regulation of absorption andABC 1-mediated efflux of cholesterol by RXR heterodimers
-
Repa, J.J. et al. (2000) Regulation of absorption andABC 1-mediated efflux of cholesterol by RXR heterodimers. Science 289, 1524-1529
-
(2000)
Science
, vol.289
, pp. 1524-1529
-
-
Repa, J.J.1
-
40
-
-
0034710965
-
Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXRα
-
Venkateswaran, A. et al. (2000) Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXRα. Proc. Natl. Acad. Sci. U. S. A. 97, 12097-12102
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 12097-12102
-
-
Venkateswaran, A.1
-
41
-
-
0034623288
-
Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor
-
Costet, P. et al. (2000) Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor. J. Biol. Chem. 275, 28240-28245
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 28240-28245
-
-
Costet, P.1
-
42
-
-
0035083516
-
Structure, function and regulation of the ABC1 gene product
-
Schmitz, G. and Langmann, T. (2001) Structure, function and regulation of the ABC1 gene product. Curr. Opin. Lipidol. 12, 129-140
-
(2001)
Curr. Opin. Lipidol.
, vol.12
, pp. 129-140
-
-
Schmitz, G.1
Langmann, T.2
-
44
-
-
0033864582
-
Peroxisome proliferator-activated receptor 7 ligands inhibit development of atherosclerosis in LDL receptor-deficient mice
-
Li, A.C. et al. (2000) Peroxisome proliferator-activated receptor 7 ligands inhibit development of atherosclerosis in LDL receptor-deficient mice. J. Clin. Invest. 106, 523-531
-
(2000)
J. Clin. Invest.
, vol.106
, pp. 523-531
-
-
Li, A.C.1
-
45
-
-
0035093258
-
Troglitazone inhibits formation of early atherosclerotic lesions in diabetic and nondiabetic low density lipoprotein receptor-deficient mice
-
Collins, A. R. et al. (2001) Troglitazone inhibits formation of early atherosclerotic lesions in diabetic and nondiabetic low density lipoprotein receptor-deficient mice. Arterioscler. Thromb. Vasc. Biol. 21, 365-371
-
(2001)
Arterioscler. Thromb. Vasc. Biol.
, vol.21
, pp. 365-371
-
-
Collins, A.R.1
-
46
-
-
0035097590
-
Troglitazone inhibits atherosclerosis in apolipoprotein E-knockout mice: Pleiotropic effects on CD36 expression and HDL
-
Chen, Z. et al. (2001) Troglitazone inhibits atherosclerosis in apolipoprotein E-knockout mice: pleiotropic effects on CD36 expression and HDL. Arterioscler. Thromb. Vasc. Biol. 21, 372-377
-
(2001)
Arterioscler. Thromb. Vasc. Biol.
, vol.21
, pp. 372-377
-
-
Chen, Z.1
-
47
-
-
0035957006
-
Reduction of atherosclerosis in apolipoprotein E-knockout mice by activation of the retinoid X receptor
-
Claudel, T. et al. (2001) Reduction of atherosclerosis in apolipoprotein E-knockout mice by activation of the retinoid X receptor. Proc. Natl. Acad. Sci. U. S. A. 98, 2610-2615
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 2610-2615
-
-
Claudel, T.1
-
48
-
-
0034773966
-
Autoregulation of the human liver X receptor α promoter
-
Laffitte, B. A. et al. (2001) Autoregulation of the human liver X receptor α promoter. Mol. Cell. Biol. 21, 7558-7568
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 7558-7568
-
-
Laffitte, B.A.1
|