Prospects for stem cell therapeutics: Myths and medicines

Current Opinion in Genetics and Development

Volumn 12, Issue 5, 2002, Pages 607-613

  Daley, George Q ^a,b  

^a WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADOPTIVE IMMUNOTHERAPY; CELL FUNCTION; CELL TYPE; HEMATOPOIESIS; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; LITERATURE; NERVE CELL DEGENERATION; PARKINSON DISEASE; PATHOPHYSIOLOGY; PHENOTYPE; PRIORITY JOURNAL; REVIEW; STEM CELL;

ANIMALIA;

EID: 0036776747     PISSN: 0959437X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-437X(02)00346-5     Document Type: Review

References (63)

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6. Transplantation of allogeneic or xenogeneic bone marrow within the donor stromal microenvironment
7. Turning brain into blood: A hematopoietic fate adopted by adult neural stem cells in vivo
8. Hematopoietic potential of stem cells isolated from murine skeletal muscle
9. Dystrophin expression in the mdx mouse restored by stem cell transplantation
10. Muscle regeneration by bone marrow-derived myogenic progenitors
11. Derivation of hepatocytes from bone marrow cells in mice after radiation-induced myeloablation
12. Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell
13. Liver repopulation and correction of metabolic liver disease by transplanted adult mouse pancreatic cells
14. Purified hematopoietic stem cells can differentiate into hepatocytes in vivo
15. Bone marrow cells regenerate infarcted myocardium
16. Identification of a candidate human neurohematopoietic stem-cell population
17. Hematopoietic potential of neural stem cells
18. Liver from bone marrow in humans
19. Bone marrow origin of hematopoietic progenitors and stem cells in murine muscle
20. Muscle-derived hematopoietic stem cells are hematopoietic in origin
21. Hematopoietic competence is a rare property of neural stem cells that may depend on genetic and epigenetic alterations
22. Cytoplasmic activation of human nuclear genes in stable heterocaryons
23. Plasticity of the differentiated state
24. Expression of muscle genes in heterokaryons depends on gene dosage
25. How fixed is the differentiated state? Lessons from heterokaryons
26. Viable offspring derived from fetal and adult mammalian cells
27. Monoclonal mice generated by nuclear transfer from mature B and T donor cells
28. Pluripotency of mesenchymal stem cells derived from adult marrow
29. Characterization of multipotent adult progenitor cells, a subpopulation of mesenchymal stem cells
30. Multipotent adult progenitor cells from bone marrow differentiate into functional hepatocyte-like cells
31. Human bone marrow stem cells exhibit neural phenotypes and ameliorate neurological deficits after grafting into the ischemic brain of rats
32. Origin of endothelial progenitors in human postnatal bone marrow
33. Epigenetic instability in ES cells and cloned mice
34. Changing potency by spontaneous fusion
35. Bone marrow cells adopt the phenotype of other cells by spontaneous cell fusion
36. Nuclear reprogramming of somatic cells by in vitro hybridization with ES cells
37. Reprogramming fibroblasts to express T-cell functions using cell extracts
38. Cell replacement therapies for central nervous system disorders
39. Bilateral caudate and putamen grafts of embryonic mesencephalic tissue treated with lazaroids in Parkinson's disease
40. Transplantation of embryonic dopamine neurons for severe Parkinson's disease
41. Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model
42. Vertebrate embryonic cells will become nerve cells unless told otherwise
43. Embryonic stem cell-derived glial precursors: A source of myelinating transplants
44. Enrichment of neurons and neural precursors from human embryonic stem cells
45. Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease
46. Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells
47. Neural progenitors from human embryonic stem cells
48. Induced neuronal differentiation of human embryonic stem cells
49. In vitro differentiation of transplantable neural precursors from human embryonic stem cells
50. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen
51. Reversal of insulin-dependent diabetes using islets generated in vitro from pancreatic stem cells
52. Multipotential nestin-positive stem cells isolated from adult pancreatic islets differentiate ex vivo into pancreatic endocrine, exocrine, and hepatic phenotypes
53. Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets
54. Insulin production by human embryonic stem cells
55. Insulin secreting cells derived from embryonic stem cells normalize glycemia in streptozotocin-induced diabetic mice
56. The in vitro development of blastocyst-derived embryonic stem cell lines: Formation of visceral yolk sac, blood islands and myocardium
57. ES cells have only a limited lymphopoietic potential after adoptive transfer into mouse recipients
58. In vitro generation of lymphoid precursors from embryonic stem cells
59. A limited temporal window for the derivation of multilineage repopulating hematopoietic progenitors during embryonal stem cell differentiation in vitro
60. Clonal analysis of differentiating embryonic stem cells reveals a hematopoietic progenitor with primitive erythroid and adult lymphoid-myeloid potential
61. HoxB4 confers definitive lymphoid-myeloid engraftment potential on embryonic stem cell and yolk sac hematopoietic progenitors
62. Correction of a genetic defect by nuclear transplantation and combined cell and gene therapy
63. From the cover: Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells