Correction of a genetic defect by nuclear transplantation and combined cell and gene therapy

Cell

Volumn 109, Issue 1, 2002, Pages 17-27

  Rideout III, William M ^a   Hochedlinger, Konrad ^a,b   Kyba, Michael ^a   Daley, George Q ^a,c   Jaenisch, Rudolf ^a,d  

^a WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^b UNIVERSITY OF VIENNA   (Austria)

^c HARVARD MEDICAL SCHOOL   (United States)

^d MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN; RAG2 PROTEIN; RECOMBINANT DNA;

ADOPTIVE IMMUNOTHERAPY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLASTOCYST; BONE MARROW; BONE MARROW CELL; CELL CLONING; CELL CULTURE; CELL DIFFERENTIATION; CELL ISOLATION; CELL NUCLEUS TRANSPLANTATION; CONTROLLED STUDY; DISEASE MODEL; ENUCLEATION; GENE MUTATION; GENE STRUCTURE; GENE THERAPY; GENETIC DISORDER; GENETIC RECOMBINATION; HEMATOPOIETIC CELL; IMMUNE DEFICIENCY; IMMUNOCOMPETENCE; IN VITRO STUDY; LYMPHOID CELL; MOUSE MUTANT; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN DETERMINATION; STEM CELL; TETRAPLOIDY; TIME;

ANIMALIA;

EID: 0037023568     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(02)00681-5     Document Type: Article

References (47)

1. Rejection of class I MHC-deficient haemopoietic cells by irradiated MHC- matched mice
2. The effects of HOXB4 in human primitive hematopoietic progenitors are concentration dependent: High levels of HOXB4 lead to increased myeloid differentiation and a reduction in proliferative capacity
3. Suppression of SHP-2 and ERK signalling promotes self-renewal of mouse embryonic stem cells
4. Genomic sequencing
5. Transgenic bovine chimeric offspring produced from somatic cell-derived stem-like cells
6. Therapeutic cloning: Concepts and practicalities
7. Intraembryonic, but not yolk sac hematopoietic precursors, isolated before circulation, provide long-term multilineage reconstitution
8. Targetted correction of a mutant HPRT gene in mouse embryonic stem cells
9. Differentiation of cardiomyocytes in floating embryoid bodies is comparable to fetal cardiomyocytes
10. Hybrid vigor, fetal overgrowth, and viability of mice derived by nuclear cloning and tetraploid embryo complementation
11. Monoclonal mice generated by nuclear transfer from mature B and T donor cells
12. A limited temporal window for the derivation of multilineage repopulating hematopoietic progenitors during embryonal stem cell differentiation in vitro
13. Identification and characterization of hematopoietic stem cells from the yolk sac of the early mouse embryo
14. Hematopoietic colony-forming cells derived from human embryonic stem cells
15. Mouse embryonic stem (ES) cell lines established from neuronal cell-derived cloned blastocysts
16. Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytes
17. Hematopoietic commitment during embryonic stem cell differentiation in culture
18. The NK1.1 antigen in NK-mediated F1 antiparent killing in vitro
19. HoxB4 confers definitive lymphoid-myeloid engraftment potential on embryonic stem cell and yolk sac hematopoietic progenitors
20. Simplified mammalian DNA isolation procedure
21. Natural killer cells weakly resist engraftment of allogeneic, long- term, multilineage-repopulating hematopoietic stem cells
22. Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells
23. Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets
24. A novel immunodeficient mouse model - RAG2 × common cytokine receptor gamma chain double mutants - Requiring exogenous cytokine administration for human hematopoietic stem cell engraftment
25. ES cells have only a limited lymphopoietic potential after adoptive transfer into mouse recipients
26. Isolation of pluripotent embryonic stem cells from reprogrammed adult mouse somatic cell nuclei
27. Derivation of completely cell culture-derived mice from early-passage embryonic stem cells
28. RAG and RAG defects
29. Clonal analysis of differentiating embryonic stem cells reveals a hematopoietic progenitor with primitive erythroid and adult lymphoid-myeloid potential
30. Reconstitution of B cell subsets in Rag deficient mice by transplantation of in vitro differentiated embryonic stem cells
31. Neural progenitors from human embryonic stem cells
32. Nuclear cloning and epigenetic reprogramming of the genome
33. Overexpression of HOXB4 in hematopoietic cells causes the selective expansion of more primitive populations in vitro and in vivo
34. Overexpression of HOXB3 in hematopoietic cells causes defective lymphoid development and progressive myeloproliferation
35. Virus-transformed pre-B cells show ordered activation but not inactivation of immunoglobulin gene rearrangement and transcription
36. RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement
37. Efficient production of Cre-mediated site-directed recombinants through the utilization of the puromycin resistance gene, pac: A transient gene-integration marker for ES cells
38. Genetics: Please don't call it cloning!
39. Full-term development of mice from enucleated oocytes injected with cumulus cell nuclei
40. Mice cloned from embryonic stem cells
41. Differentiation of embryonic stem cell lines generated from adult somatic cells by nuclear transfer
42. Generation of completely embryonic stem cell-derived mutant mice using tetraploid blastocyst injection
43. Control of V(D)J recombinational accessibility of the D beta 1 gene segment at the TCR beta locus by a germline promoter
44. Multiple hematopoietic lineages develop from embryonic stem (ES) cells in culture
45. Viable offspring derived from fetal and adult mammalian cells
46. In vitro differentiation of transplantable neural precursors from human embryonic stem cells