Ecological significance of compatible solute accumulation by micro- organisms: From single cells to global climate

FEMS Microbiology Reviews

Volumn 24, Issue 3, 2000, Pages 263-290

  Welsh, David T ^a  

^a UNIVERSITY OF PARMA   (Italy)

Author keywords

Climate regulation; Compatible solute; Desiccation resistance; Dimethylsulfide; Dimethylsulfoniopropionate; Glycine betaine; Methanogenesis; Osmoadaptation; Stress tolerance; Thermotolerance; Trehalose

Indexed keywords

DIMETHYL SULFIDE; METHANE; POTASSIUM ION; TREHALOSE;

ADAPTATION; ARCHAEBACTERIUM; CELL GROWTH; COLD TOLERANCE; CULTURE MEDIUM; DESICCATION; ECOLOGY; EVOLUTION; GLOBAL CLIMATE; HEAT TOLERANCE; MICROORGANISM; NONHUMAN; OSMOREGULATION; OSMOTIC STRESS; REVIEW;

ADAPTATION, PHYSIOLOGICAL; ALGAE; ARCHAEA; BACTERIA; CLIMATE; ECOSYSTEM; EVOLUTION; FUNGI;

EID: 0034032756     PISSN: 01686445     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-6445(99)00038-8     Document Type: Review

References (310)

1. Brown, A.D. (1990) Microbial Water Stress: Physiology, Principles and Perspectives. John Willey and Sons Chichester.
2. Csonka, L.N. (1989) Physiological and genetic responses of bacteria to osmotic stress. Microbiol. Rev. 53, 121-147.
3. Taiz, L. (1984) Plant cell expansion: regulation of cell wall mechanical properties. Annu. Rev. Plant Physiol. 35, 585-657.
4. Brown, A.D. (1976) Microbial water stress. Bacteriol. Rev. 40, 803-846.
5. Galinski, E.A. and Trüper, H.G. (1994) Microbial behaviour in salt stressed ecosystems. FEMS Microbiol. Rev. 15, 95-108.
6. Eisenberg, H. and Wachtel, E.J. (1987) Structural studies of halophilic proteins, ribosomes and organelles of bacteria adapted to extreme salt concentrations. Annu. Rev. Biophys. Chem. 16, 69-92.
7. Brown, A.D. (1963) The peripheral structures of Gram-negative bacteria. IV. The cation sensitive dissolution of the cell membrane of the halophilic bacterium, Halobacterium halobium. Biochim. Biophys. Acta 75, 425-435.
8. Pollard, A. and Wyn Jones, R.G. (1981) Enzyme activities in concentrated solutions of glycine betaine and other solutes. Planta 144, 291-298.
9. Wyn Jones, R.G. and Storey, R. (1981) Betaines. In: The Physiology and Biochemistry of Drought Resistant Plants (Paleg, L.G. and Aspinall, D., Eds.), pp. 171-204. Academic Press, Sydney.
10. Warr, S.R.C., Reed, R.H. and Stewart, W.D.P. (1984) Osmotic adjustment of cyanobacteria: the effects of NaCl, KCl, sucrose and glycine betaine on glutamine synthetase activity in a marine and halotolerant strain. J. Gen. Microbiol. 130, 2169-2175.
11. Gabbay-Azaria, R., Tel-Or, E. and Schönfeld, M. (1988) Glycine betaine as an osmoregulant and compatible solute in the marine cyanobacterium Spirulina subsala. Arch. Biochem. Biophys. 264, 333-339.
12. Papageorgiou, G.C. and Murata, N. (1995) Unusually strong stabilization effects of glycine betaine on the structure and function of the oxygen-evolving photosystem II complex. Photosynth. Res. 44, 243-252.
13. Borowitzka, L.J. (1981) Solute accumulation and regulation of cell water activity. In: The Physiology and Biochemistry of Drought Resistant Plants (Paleg, L.G. and Aspinall, D., Eds.), pp. 97-130. Academic Press, Sydney.
14. Greenway, H. and Stetter, T.L. (1979) Accumulation of proline and sucrose during the first hours after transfer of Chlorella emersonii to high NaCl. Aust. J. Plant Physiol. 6, 69-79.
15. Ahmad, I. and Hellebust, J.A. (1984) Osmoregulation in the extremely euryhaline marine microalga Chlorella autotrophica. Plant Physiol. 74, 1010-1015.
16. Liss, P.S., Hatton, A.D., Malin, G., Nightingale, P.D. and Turner, S.M. (1997) Marine sulphur emissions. Phil. Trans. R. Soc. Lond. B. 352, 159-169.
17. Blunden, G., Smith, B.E., Irons, M.W., Yang, M., Roch, O.G. and Patel, A.V. (1992) Betaines and tertiary sulphonium compounds from 63 species of marine algae. Biochem. Syst. Ecol. 20, 373-388.
18. Meikle, A.J., Reed, R.H. and Gadd, G.M. (1988) Osmotic adjustment and accumulation of organic solutes in whole cells and protoplasts of Saccharomyces cerevisiae. J. Gen. Microbiol. 134, 3049-3060.
19. Larsson, C., Morales, C., Gustafsson, L. and Adler, L. (1990) Osmoregulation of the salt-tolerant yeast Debaryomyces hansenii grown in a chemostat at different salinities. J. Bacteriol. 172, 1769-1774.
20. Jennings, D.H. (1990) Osmophiles. In: Microbiology of Extreme Environments (Edwards, C., Ed.), pp. 117-146. Open University Press, Milton Keynes.
21. Reed, R.H., Richardson, D.L., Warr, S.R.C., Moore, D.J. and Stewart, W.D.P. (1984) Carbohydrate accumulation and osmotic stress in cyanobacteria. J. Gen. Microbiol. 130, 1-4.
22. Mackay, M.A., Norton, R.S. and Borowitzka, L.J. (1984) Organic osmoregulatory solutes in cyanobacteria. J. Gen. Microbiol. 130, 2177-2191.
23. 13C nuclear magnetic resonance spectroscopy. FEMS Microbiol. Ecol. 13, 145-150.
24. Severin, J., Wohlfarth, A. and Galinski, E.A. (1992) The predominant role of recently discovered tetrahydropyrimidines for the osmoadaptation of halophilic eubacteria. J. Gen. Microbiol. 138, 1629-1638.
25. Welsh, D.T., Lindsay, Y.E., Caumette, P., Herbert, R.A. and Hannan, J. (1996) Identification of trehalose and glycine betaine as compatible solutes in the moderately halophilic sulfate reducing bacterium Desulfovibrio halophilus. FEMS Microbiol. Lett. 140, 203-207.
26. Measures, J.C. (1975) Role of amino acids in osmoregulation of non-halophilic bacteria. Nature 257, 398-400.
27. D'Souza-Ault, M.R., Smith, L.T. and Smith, G.M. (1993) Roles of N-acetylglutaminylglutamine amide and glycine betaine in adaptation of Pseudomonas aeruginosa. Appl. Environ. Microbiol. 59, 473-4-78.
28. + and glutamate during osmoadaptation in continuous culture. J. Gen. Microbiol. 137, 745-750.
29. Killham, K. and Firestone, M.K. (1984) Salt stress control of intracellular solutes in streptomycetes indigenous to saline soils. Appl. Environ. Microbiol. 47, 301-306.
30. Robertson, D.E., Noll, D., Roberts, M.F., Menaia, G.F. and Boone, D.R. (1990) Detection of the osmoregulator betaine in methanogens. Appl. Environ. Microbiol. 56, 563-565.
31. Robertson, D.E., Roberts, M.F., Belay, N., Stetter, K.O. and Boone, D.R. (1990) Occurrence of β-glutamate, a novel osmolyte in marine methanogenic bacteria. Appl. Environ. Microbiol. 56, 1504-1508.
32. Yancey, P.H., Clark, M.E., Hand, S.C., Bowlus, R.D. and Somero, G.N. (1982) Living with water stress: evolution of osmolyte systems. Science 217, 1214-1222.
33. Higgins, C.F., Cairney, J., Stirling, D.A., Sutherland, L. and Booth, I.R. (1987) Osmotic regulation of gene expression: ionic strength as an intracellular signal. Trends Biochem. Sci. 12, 339-344.
34. Booth, I.R. and Higgins, C.F. (1990) Enteric bacteria and osmotic stress: intracellular potassium glutamate as a secondary signal of osmotic stress. FEMS Microbiol. Rev. 75, 125-142.
35. Winzor, C.L., Winzor, D.J., Paleg, L.G., Jones, G.P. and Naidu, B.P. (1992) Rationalisation of the effects of compatible solutes on protein stability in terms of thermodynamic nonideality. Arch. Biochem. Biophys. 296, 102-107.
36. Galinski, E.A. (1993) Compatible solutes of halophilic eubacteria: molecular principles, water-solute interaction, stress protection. Experientia 49, 487-496.
37. Record Jr., M.T., Courtney, E.S., Cayley, D.S. and Guttman, H.J. (1998) Responses of E. coli to osmotic stress large changes in amounts of cytoplasmic solutes and water. Trends Biochem. Sci. 23, 143-148.
38. Kempf, B. and Bremer, E. (1998) Uptake and synthesis of compatible solutes as microbial stress responses to high-osmolarity environments. Arch. Microbiol. 170, 319-330.
39. Galinski, E.A. (1995) Osmoadaptation in bacteria. Adv. Microb. Physiol. 37, 272-328.
40. Poolman, B. and Glaasker, E. (1998) Regulation of compatible solute accumulation in bacteria. Mol. Microbiol. 29, 397-407.
41. Booth, I.R. and Louis, P. (1999) Managing hypoosmotic stress: aquaporins and mechanosensitive channels in Escherichia coli. Curr. Opin. Microbiol. 2, 166-169.
42. Timasheff, S.N. (1998) Control of protein stability and reactions by weakly interacting cosolvents: the simplicity of the complicated. Adv. Protein Chem. 51, 355-432.
43. Galinski, E.A. and Trüper, H.G. (1982) Betaine, a compatible solute in the extremely halophilic phototrophic bacterium Ectothiorhodospira halochloris. FEMS Microbiol. Lett. 13, 357-360.
44. Galinski, E.A., Pfeiffer, H.P. and Trüper, H.G. (1985) 1,4,5,6-Tetrahydro-2-methyl-4-pyrimidinecarboxylic acid. A novel amino acid from the halophilic phototrophic bacteria of the genus Ectothiorhodospira halochloris. Eur. J. Biochem. 149, 135-139.
45. Galinski, E.A. and Herzog, R.M. (1990) The role of trehalose as a substitute for nitrogen-containing compatible solutes (Ectothiorhodospira halochloris). Arch. Microbiol. 153, 607-613.
46. Herzog, R.M., Galinski, E.A. and Trüper, H.G. (1990) Degradation of the compatible solute trehalose in Ectothiorhodospira halochloris: isolation and characterization of trehalase. Arch. Microbiol. 153, 600-606.
47. Turner, S.M., Malin, G., Liss, P.S., Harbour, D.S. and Holligan, P.M. (1988) The seasonal variation of dimethylsulphide and dimethylsulphoniopropionate concentrations in nearshore waters. Limnol. Oceanogr. 33, 364-375.
48. Dinnibier, U., Limpinsel, E., Schmid, R. and Bakker, E.P. (1988) Transient accumulation of potassium glutamate and its replacement by trehalose during adaptation of growing cells of Escherichia coli K-12 to elevated sodium chloride concentrations. Arch. Microbiol. 150, 348-357.
49. Hengge-Aronis, R., Klein, W., Lange, R., Rimmele, M. and Boos, W. (1991) Trehalose synthesis genes are controlled by the putative sigma factor encoded by rpoS and are involved in stationary-phase thermotolerance in Escherichia coli. J. Bacteriol. 173, 7918-7924.
50. Strom, A.R. and Kaasen, I. (1993) Trehalose metabolism in Escherichia coli: stress protection and stress regulation of gene expression. Mol. Microbiol. 8, 205-210.
51. Thevelein, J.M. (1984) Regulation of trehalose mobilization in fungi. Microbiol. Rev. 48, 42-59.
52. Elbein, A.D. (1974) The metabolism of α,α-trehalose. Adv. Carbohydr. Chem. Biochem. 30, 227-256.
53. Kane, S.M. and Roth, R. (1974) Carbohydrate metabolism during ascospore development in yeast. J. Bacteriol. 118, 8-14.
54. Wright, B.E. (1978) Concepts of differentiation. In: The Filamentous Fungi (Smith, J.E. and Berry, D.R., Eds.), pp. 1-7. Edward Arnold, London.
55. Van Laere, A. (1989) Trehalose, reserve and/or stress metabolite. FEMS Microbiol. Rev. 63, 201-210.
56. Hottiger, T., Boller, T. and Wiemken, A. (1987) Rapid changes of heat and desiccation tolerance correlated with changes in trehalose content in Saccharomyces cerevisiae cells subjected to temperature shifts. FEBS Lett. 220, 113-115.
57. Hottiger, T., Boller, T. and Wiemken, A. (1989) Correlation of trehalose content and heat resistance in yeast mutants altered in the RAS/adenylate cyclase pathway: is trehalose a thermoprotectant? FEBS Lett. 255, 431-434.
58. Piper, P.W. and Lockheart, A. (1988) A temperature-sensitive mutant of Saccharomyces cerevisiae defective in the specific phosphatase of trehalose biosynthesis. FEMS Microbiol. Lett. 49, 245-250.
59. Atfield, P.V. (1987) Trehalose accumulates in Saccharomyces cerevisiae during exposure to agents that induce heat shock response. FEBS Lett. 225, 259-263.
60. Ensign, J.C. (1978) Formation, properties and germination of actinomycete spores. Annu. Rev. Microbiol. 32, 185-219.
61. Emyanitoff, R.G. and Wright, B.E. (1979) Effect of intracellular carbohydrates on heat resistance of Dictyostelium discoideum spores. J. Bacteriol. 140, 1008-1012.
62. Brana, A.F., Mendez, C., Diaz, A., Manzanal, M.B. and Hardisson, C. (1986) Glycogen and trehalose accumulation during colony development in Streptomyces antibioticus. J. Gen. Microbiol. 132, 1319-1326.
63. McBride, M.J. and Ensign, J.C. (1987) Effects of intracellular trehalose content on Streptomyces griseus spores. J. Bacteriol. 169, 4995-5001.
64. Martin, A., Auger, E.A., Blum, P.H. and Schultz, J.E. (1989) Genetic basis of starvation survival in nondifferentiating bacteria. Annu. Rev. Microbiol. 43, 293-316.
65. Siegele, D.A. and Kolter, R. (1992) Life after log. J. Bacteriol. 174, 345-348.
66. Low, P.S. (1985) Molecular basis of the biological compatibility of nature's solutes. In: Transport Processes - Iono- and Osmoregulation (Gilles, R. and Gilles-Baillien, M., Eds.), pp. 469-477. Springer-Verlag, Berlin.
67. Arakawa, T. and Timasheff, S.N. (1985) The stabilization of proteins by osmolytes. Biophys. J. 47, 411-414.
68. Hecker, L.I. and Sussman, A.S. (1973) Activity and heat stability of trehalase from the mycelium and ascospores of Neurospora. J. Bacteriol. 115, 582-591.
69. Back, J.F., Oakenfull, D. and Smith, M.B. (1979) Increased thermal stability of proteins in the presence of sugars and polyols. Biochemistry 18, 5191-5196.
70. Arakawa, T. and Timasheff, S.N. (1982) Stabilisation of protein structure by sugars. Biochemistry 21, 6536-6544.
71. Tsuchido, T., Aoki, I. and Takano, M. (1989) Interaction of the fluorescent dye 1-N-phenylnaphthlamine with Escherichia coli cells during heat stress and recovery from heat stress. J. Gen. Microbiol. 135, 1941-1947.
72. Tsuchido, T., Katsui, N., Takeuchi, A., Takano, M. and Shibasaki, L. (1985) Destruction of the outer membrane permeability barrier of Escherichia coli by heat treatment. Appl. Environ. Microbiol. 50, 298-303.
73. Crowe, J.H., Crowe, L.M., Carpenter, J.F. and Aurell Wistrom, C. (1987) Stabilisation of dry phospholipid bilayers and proteins by sugars. Biochem. J. 242, 1-10.
74. Lee, C.W.B., Das Gupta, S.K., Mattai, J., Shipley, G.G., Abdel-Mageed, H., Makriyannis, A. and Griffin, R.G. (1989) Characterisation of the Lλ phase in trehalose-stabilised dry membranes by solid-state NMR and x-ray diffraction. Biochemistry 28, 5000-5009.
75. Rudolph, A.S., Crowe, J.H. and Crowe, L.M. (1986) Effects of three stabilising agents - proline, betaine and trehalose - on membrane phospholipids. Arch. Biochem. Biophys. 245, 134-143.
76. Mazur, P. (1968) Survival of fungi after freezing and desiccation. In: The Fungi, Vol. 3. The Fungal Population (Ainsworth, G.C. and Sussman, A.S., Eds.), pp. 325-394. Academic Press, New York.
77. Hino, A., Mihara, H., Nakashima, K. and Takano, H. (1990) Trehalose levels and survival ratio of freeze-tolerant versus freeze-sensitive yeasts. Appl. Environ. Microbiol. 56, 1386-1391.
78. Van Laere, A. (1986) Resistance of germinating Phycomyces spores to desiccation, freezing and acids. FEMS Microbiol. Ecol. 38, 251-256.
79. Guy, C.L., Plesofsky-Vig, N. and Bramble, R. (1986) Heat shock protects germinating conidiospores of Neurospora crassa against freezing injury. J. Bacteriol. 167, 124-129.
80. Barbour, E.A. and Priest, F.G. (1986) The preservation of lactobacilli: A comparison of three methods. Lett. Appl. Microbiol. 2, 68-71.
81. Simione, F.P. and Brown, E.M. (1991) ATCC Preservation Methods: Freezing and Freeze Drying, 2nd edn. American Type Culture Collection, Rockville, MD.
82. De Antoni, G.L., Pérez, P., Abraham, A. and Añón, M.C. (1989) Trehalose, a cryoprotectant for Lactobacillus bulgaricus. Cryobiology 26, 149-153.
83. Hand, S.C. and Somero, G.N. (1982) Urea and methylamine effects on rabbit muscle phosphofructokinase: catalytic stability and aggregation state as a function of pH and temperature. J. Biol. Chem. 257, 734-741.
84. Carpenter, J.F., Hand, S.C., Crowe, L.M. and Crowe, J.H. (1986) Cryoprotection of phosphofructokinase with organic solutes: characterisation of enhanced protection in the presence of divalent cations. Arch. Biochem. Biophys. 250, 505-512.
85. Nishiguchi, M.K. and Somero, G.N. (1992) Temperature- and concentration-dependence of compatibility of the organic osmolyte β-dimethylsulfoniopropionate. Cryobiology 29, 118-124.
86. Carpenter, J.F. (1993) Stabilization of proteins during freezing and dehydration: application of lessons from nature. Cryobiology 30, 220-221.
87. Bhandal, I.S., Hauptman, R.M. and Widholm, J.M. (1985) Trehalose as cryoprotectant for the freeze preservation of carrot and tobacco cells. Plant Physiol. 78, 430-432.
88. Honadel, T.E. and Killian, G.J. (1988) Cryopreservation of murine embryos with trehalose and glycerol. Cryobiology 25, 331-337.
89. Knight, J. (1998) Life on ice. New Scientist 2132, 24-28.
90. Asahina, E. and Tanno, K. (1964) A large amount of trehalose in a frost resistant insect. Nature 204, 1222.
91. Shimida, K., Sakagami, S.F., Honma, K. and Tutsui, H. (1984) Seasonal changes of glycogen/trehalose contents, supercooling points and survival rate in mature larvae of the overwintering soybean pod borer Leguminovora glycinivorella. J. Insect Physiol. 30, 369-373.
92. Potts, M. (1994) Desiccation tolerance of prokaryotes. Microbiol. Rev. 58, 755-805.
93. Madin, K.A.C. and Crowe, J.H. (1975) Anhydrobiosis in nematodes: carbohydrate and lipid metabolism during dehydration. J. Exp. Zool. 193, 335-342.
94. Crowe, J.H., Hoekstra, F.A. and Crowe, L.M. (1992) Anhydrobiosis. Annu. Rev. Physiol. 54, 579-599.
95. Louis, P., Trüper, H.G. and Galinski, E.A. (1994) Survival of Escherichia coli during drying and storage in the presence of compatible solutes. Appl. Microbiol. Biotechnol. 41, 684-688.
96. Gadd, G.M., Chalmers, K. and Reed, R.H. (1987) The role of trehalose in dehydration resistance of Saccharomyces cerevisiae. FEMS Microbiol. Lett. 48, 249-254.
97. Welsh, D.T. and Herbert, R.A. (1999) Osmotically induced intracellular trehalose, but not glycine betaine accumulation promotes desiccation tolerance in Escherichia coli. FEMS Microbiol. Lett. 174, 57-63.
98. Leslie, S.B., Israeli, E., Lighthart, B., Crowe, J.H. and Crowe, L.M. (1995) Trehalose and sucrose protect both membranes and proteins in intact bacteria during drying. Appl. Environ. Microbiol. 61, 3592-3597.
99. Crowe, L.M., Crowe, J.H., Rudolph, A., Womersley, C. and Appel, L. (1985) Preservation of freeze dried liposomes by trehalose. Arch. Biochem. Biophys. 242, 240-247.
100. Eleutherio, E.C., Araujo, P.S. and Panek, A.D. (1993) Role of the trehalose carrier in dehydration resistance of Saccharomyces cereisiae. Biochim. Biophys. Acta 1156, 263-266.
101. Kets, E.P.W. and de Bont, J.A.M. (1994) Protective effects of betaine on the survival of Lactobacillus plantarium subjected to drying. FEMS Microbiol. Lett. 116, 251-256.
102. Kets, E.P.W., Teunissen, P.J.M. and de Bont, J.A.M. (1996) Effect of compatible solutes on survival of lactic acid bacteria subjected to drying. Appl. Environ. Microbiol. 62, 259-261.
103. Crowe, J.H., Crowe, L.M. and Jackson, S.A. (1983) Preservation of structural and functional activity in lypholilized sarcoplasmic reticulum. Arch. Biochem. Biophys. 220, 477-484.
104. Carpenter, J.F., Martin, B., Crowe, L.M. and Crowe, J.H. (1987) Stabilization of phosphofructokinase during air-drying with sugars and sugar/transition metal mixtures. Cryobiology 24, 455-464.
105. Blackley, D., Tolliday, B., Colaço, C.A.L.S. and Roser, B. (1991) Dry, instant blood typing plate for bedside use. Lancet 336, 854-855.
106. Colaço, C.A.L.S., Sen, S., Thangavelu, M., Pinder, S. and Roser, B. (1992) Extraordinary stability of enzymes dried in trehalose: simplified molecular biology. Biotechniques 10, 1007-1011.
107. Colaço, C.A.L.S., Smith, C.J.S., Sen, S., Roser, D.H., Newman, Y., Ring, S. and Roser, B.J. (1994) Chemistry of protein stabilization by trehalose. In: Formulation and Delivery of Proteins and Peptides (Cleland, J.L. and Langer, R., Eds.), pp. 222-240. ACS Symposium Series 567. American Chemical Society, Washington, DC.
108. Crowe, J.H., Crowe, L.M., Carpenter, J.F., Rudolph, A.S., Aurell Winstrom, C., Spargo, B.J. and Anchordoguy, T.J. (1988) Interactions of sugars with membranes. Biochim. Biophys. Acta 947, 367-384.
109. Roser, B. (1991) Trehalose drying: a novel replacement for freeze-drying. BioPharm 8, 47-53.
110. Goodrich, R.P. (1993) Lyophilization of human red blood cells: applications and implications for transfusion medicine. Cryobiology 30, 240-241.
111. Crowe, L.M., Womersley, C., Crowe, J.H., Reid, D., Appel, L. and Rudolph, A. (1986) Prevention of fusion and leakage in freeze-dried liposomes by carbohydrates. Biochim. Biophys. Acta 861, 131-140.
112. Rudolph, B.R., Chadresekhar, I., Gaber, B.P. and Nagumo, M. (1990) Molecular modelling of saccharide-lipid interactions. Chem. Phys. Lipids 53, 243-261.
113. Hoekstra, F.A., Crowe, J.H. and Crowe, L.M. (1991) Effect of sucrose on phase behaviour of membranes of intact pollen of Typha latifolia L., as measured with Fourier transform infrared spectroscopy. Plant Physiol. 97, 1073-1079.
114. Hoekstra, F.A., Crowe, J.H., Crowe, L.M., Vanroeket, T. and Vanmeer, E. (1992) Do phospholipids and sucrose determine membranes phase transitions in dehydrating pollen species? Plant Cell Environ. 15, 601-606.
115. Leslie, S.B., Teter, S.A., Crowe, L.M. and Crowe, J.H. (1994) Trehalose lowers membrane phase transitions in dry yeast cells. Biochim. Biophys. Acta 1192, 7-13.
116. Carpenter, J.F. and Crowe, J.H. (1988) Modes of stabilization of a protein by organic solutes during desiccation. Cryobiology 25, 459-470.
117. Carpenter, J.F. and Crowe, J.H. (1989) An infrared spectroscopy study of the interactions of carbohydrates with dried proteins. Biochemistry 28, 3916-3922.
118. Burke, M.J. (1986) The glassy state and survival of anhydrous biological systems. In: Membranes, Metabolism and Dry Organisms (Leopold, C., Ed.), pp. 358-363. Cornell University Press, Ithaca, NY.
119. Green, J.L. and Angell, C.A. (1988) Phase relations and vitrification in saccharide-water solutions and the trehalose anomaly. J. Phys. Chem. 93, 2880-2882.
120. Reynolds, T.H. (1965) Chemistry of non-enzymic browning. Adv. Food Res. 14, 167-283.
121. Nursten, H.F. (1986) Maillard browning reactions in dried foodstuffs. In: Concentration and Drying of Foodstuffs (McCarthy, D., Ed.), pp. 53-68. Elsevier Applied Science, London.
122. Roser, B. (1991) Trehalose, a new approach to premium dried foods. Trends Food Sci. Technol. 7, 166-169.
123. Mansure, J.J.C., Panek, A.D., Crowe, L.M. and Crowe, J.H. (1994) Trehalose inhibits ethanol effects on intact yeast cells and liposomes. Biochim. Biophys. Acta 1191, 309-316.
124. S (rpoS). J. Bacteriol. 173, 4474-4481.
125. Lange, R. and Hengge-Aronis, R. (1991) Identification of a central regulator of stationary-phase gene expression in Escherichia coli. Mol. Microbiol. 5, 49-59.
126. Eilers, F.I., Ikuma, H. and Sussman, A.S. (1970) Changes in metabolic intermediates during activation of Neurospora ascospores. Can. J. Microbiol. 16, 1351-1356.
127. Van Laere, A.J. and Slegers, L.K. (1987) Trehalose breakdown in germinating spores of Mucor rouxii. FEMS Microbiol. Lett. 41, 247-252.
128. Gadd, G.M., Chudek, J.A., Foster, R. and Reed, R.H. (1984) The osmotic response of Penicillium ochrochloron: changes in internal solute levels in response to copper and salt stress. J. Gen. Microbiol. 130, 1969-1975.
129. Pollock, G.E. and Holmstrom, C.D. (1951) The trehalose content and the quality of active dry yeast. Cer. Chem. 28, 498-505.
130. Hoelzle, I. and Streeter, J.G. (1990) Increased accumulation of trehalose in rhizobia under 1% oxygen. Appl. Environ. Microbiol. 56, 3213-3215.
131. Sussman, A.S. (1968) Longevity and survivability of fungi. In: The Fungi, Vol. 3. The Fungal Population (Ainsworth, G.C. and Sussman, A.S., Eds.), pp. 447-486. Academic Press, New York.
132. Van den Hoek, C., Mann, D.G. and Jahns, H.M. (1995) Algae: An Introduction to Phycology. Cambridge University Press, Cambridge.
133. Wolfe, G.V., Steinke, M. and Kirst, G.O. (1997) Grazing-activated chemical defence in a unicellular marine alga. Nature 387, 894-897.
134. Stefels, J. and Dijkhuizen, L. (1996) Characteristics of DMSP-lyase in Phaeocystis sp. (Prymnesiophyceae). Mar. Ecol. Prog. Ser. 131, 307-313.
135. Sieburth, J.M. (1960) Acrylic acid an 'antibiotic' principle in Phaeocystis blooms in antarctic waters. Science 132, 676-677.
136. Dacey, J.W.H. and Wakeham, S.G. (1986) Oceanic dimethylsulfide: production during zooplankton grazing on phytoplankton. Science 233, 1314-1315.
137. Leek, C., Larsson, U., Bagander, L.E., Johansson, S. and Hajdu, S. (1990) Dimethyl sulphide in the Baltic sea: annual variability in relation to biological activity. J. Geophys. Res. 95, 3353-3363.
138. Malin, G., Liss, P.S. and Turner, S.M. (1994) Dimethyl sulfide: production and atmospheric consequences. In: The Haptophyte Algae (Green, J.C. and Leadbeater, B.S.C., Eds.), pp. 303-320. Clarendon Press, Oxford.
139. Wolfe, G.V., Sherr, E.B. and Sherr, B.F. (1994) Release and consumption of DMSP from Emiliania huxleyi during grazing by Oxyrrhis marina. Mar. Ecol. Prog. Ser. 111, 111-119.
140. Lenton, T.M. (1998) Gaia and natural selection. Nature 394, 439-447.
141. Verity, P.G., Villareal, T.A. and Smayda, T.J. (1988) Ecological investigations of blooms of colonial Phaeocystis pouchetii. II. The role of life-cycle phenomena in bloom termination. J. Plankton Res. 10, 749-766.
142. Slezak, D.M., Puskaric, S. and Herndl, G.J. (1994) Potential role of acrylic acid in bacterioplankton communities in the sea. Mar. Ecol. Prog. Ser. 105, 191-197.
143. Yang, H., McTaggart, A.T., Davidson, A.T. and Burton, H. (1994) Measurement of acrylic acid and dimethylsulfide in antarctic coastal water during a summer bloom of Phaeocystis pouchetii. In: Proceedings of the NIPR Symposium of polar biology, Vol. 7. (Hoshiai, T., Ed.), pp. 43-52. National Institute of Polar Research, Tokyo.
144. Gibson, J.A.E., Swadling, K.M. and Burton, H.R. (1996) Acrylate and dimethylsulfonio-propionate (DMSP) concentrations during an Antarctic phytoplankton bloom. In: Biological and Environmental Chemistry of DMSP and Related Sulfonium Compounds (Kiene, R.P., Visscher, P.T., Keller, M.D. and Kirst, G.O., Eds.), pp. 213-222. Plenum, New York.
145. Noordkamp, D.J.B., Schotten, M., Gieskes, W.W.C., Forney, L.J., Gottschal, J.C. and van Rijssel, M. (1998) High acrylate concentrations in the mucus of Phaeocystis globosa colonies. Aquat. Microb. Ecol. 16, 45-52.
146. Davidson, A.T. and Marchant, H.J. (1987) Binding of manganese by Antarctic Phaeocystis pouchetii and the role of bacteria in its release. Mar. Biol. 95, 481-487.
147. Laroche, D., Vézina, A.F., Levasseur, M., Gosselin, M., Stefels, J., Keller, M.D., Matrai, P.A. and Kwint, R.L.J. (1999) DMSP synthesis and exudation in phytoplankton: a modelling approach. Mar. Ecol. Prog. Ser. 180, 37-49.
148. Hill, R.W., White, B.A., Cottrell, M. and Dacey, J.W.H. (1998) Virus-mediated total release of dimethylsulfoniopropionate from marine phytoplankton: a potential climate process. Aquat. Microb. Ecol. 14, 1-6.
149. Ledyard, K.M., de Long, E.F. and Dacey, J.W.H. (1993) Characterisation of a DMSP-degrading bacterial isolate from the Sargasso Sea. Arch. Microbiol. 160, 312-318.
150. De Souza, M.P. and Yoch, D.C. (1995) Purification and characterization of dimethylsulfonio-propionate lyase from an Alcaligenes-like dimethyl sulfide producing marine isolate. Appl. Environ. Microbiol. 61, 21-26.
151. Hamilton, W.D. and Lenton, T.M. (1998) Spora and Gaia: how microbes fly with their clouds. Ethol. Ecol. Evol. 10, 1-16.
152. Welsh, D.T., Viaroli, P., Hamilton, W.D. and Lenton, T.M. (1999) Is DMSP synthesis in Chlorophycean macroalgae linked to dispersal? Ethol. Ecol. Evol. 11, 265-278.
153. Hamilton, W.D. and May, R.M. (1977) Dispersal in stable habitats. Nature 269, 578-581.
154. Blanchard, D.C. (1983) The production, distribution and bacterial enrichment of the sea salt aerosol. In: Air-Sea Exchange of Gases and Particles (Liss, P.S. and Slinn, W.G.N., Eds.), pp. 407-454. Reidel, Dordrecht.
155. Blanchard, D.C. and Syzdek, L.D. (1970) Mechanism for the water-to-air transfer and concentration of bacteria. Science 170, 626-628.
156. Wallace, G.T. and Duce, R.A. (1978) Transport of particulate organic matter by bubbles in marine water. Limnol. Oceanogr. 23, 1155-1167.
157. Brown, R.M., Larson, D.A. and Bold, H.C. (1964) Airborne algae: their abundance and heterogeneity. Science 143, 583-585.
158. Chesselet, R., Fontugne, M., Buat-Menard, P., Ezat, U. and Lambert, C.E. (1981) The origin of particulate organic carbon in the marine atmosphere as indicated by its stable carbon isotope composition. Geophys. Res. Lett. 8, 345-348.
159. Woodcock, A.H. (1948) Note concerning human respiratory irritation associated with high concentrations of plankton and mass mortality of marine organisms. J. Mar. Res. 7, 56-62.
160. Hart, T.J. (1966) Some observations on the relative abundance of marine phytoplankton in nature. In: Some Contemporary Studies in Marine Science (Barnes, H., Ed.), pp. 375-393. Allen and Unwin, London.
161. nd International Conference (Taylor, D.L. and Seliger, H.H., Eds.), pp. 29-36. Elsevier/North Holland, New York.
162. Nguyen, B.C., Belviso, S., Mihalopoulos, N., Gostan, J. and Nival, P. (1988) Dimethyl sulfide production during natural phytoplankton blooms. Mar. Chem. 24, 133-141.
163. Bratbak, G., Levasseur, M., Michaud, S., Cantin, G., Fernandez, E., Heimdal, B.R. and Heldal, M. (1995) Viral activity in relation to Emiliania huxleyi blooms: a mechanism for DMSP release? Mar. Ecol. Prog. Ser. 128, 133-142.
164. Christaki, U., Belviso, S., Dolan, J.R. and Corn, M. (1996) Assessment of the role of copepods and ciliates in the release to solution of particulate DMSP. Mar. Ecol. Prog. Ser. 141, 119-127.
165. Keller, M.D., Bellows, W.K. and Guillard, R.R.L. (1989) Dimethyl sulfide production in marine phytoplankton. In: Biogenic Sulfur in the Environment. Symp. Ser. 393 (Saltzman, E.S. and Cooper, W.J., Eds.), pp. 167-182. American Chemical Society, Washington, DC.
166. Andreae, M.O. (1986) The ocean as a source of atmospheric sulphur compounds. In: The Role of Air-Sea Exchange in Geochemical Cycling (Buat-Menard, P., Ed.), pp. 331-362. Reidel, Dordrecht.
167. Blount, P. and Moe, P.C. (1999) Bacterial mechanosensitive channels: integrating physiology, structure and function. Trends Microbiol. 7, 420-424.
168. Glaasker, E., Konings, W.N. and Poolman, B. (1996) Osmotic regulation of intracellular solute pools in Lactobacillus plantarum. J. Bacteriol. 178, 575-582.
169. Ruffert, S., Lambert, C., Peter, H., Wendisch, V.F. and Kramer, R. (1997) Efflux of compatible solutes in Corynebacterium glutamicum mediated by osmoregulated channel activity. Eur. J. Biochem. 247, 572-580.
170. Moore, D.J., Reed, R.H. and Stewart, W.D.P. (1987) A glycine betaine transport system in Aphanothece halophytica and other glycine betaine synthesising cyanobacteria. Arch. Microbiol. 147, 399-405.
171. Welsh, D.T. and Herbert, R.A. (1995) Glycine betaine transport in a halotolerant Chromatium species. FEMS Microbiol. Lett. 128, 27-32.
172. Mikkat, S., Effmert, U. and Hagemann, M. (1997) Uptake and use of the osmoprotective compounds trehalose, glucosylglycerol, and sucrose by the cyanobacterium Synechocystis sp. PCC6803. Arch. Microbiol. 167, 112-118.
173. Jebbar, M., Talibart, R., Gloux, K., Bernard, T. and Blanco, C. (1992) Osmoprotection of Escherichia coli by ectoine: Uptake and accumulation characteristics. J. Bacteriol. 174, 5027-5035.
174. Chambers, S.T., Kunin, C.M., Miller, D. and Hamada, A. (1987) Dimethylthetin can substitute for glycine betaine as an osmoprotectant molecule for Escherichia coli. J. Bacteriol. 169, 4845-4847.
175. Diaz, M.D., Visscher, P.T. and Taylor, B.F. (1992) Metabolism of dimethylsulfonio-propionate and glycine betaine by a marine bacterium. FEMS Microbiol. Lett. 96, 61-66.
176. Mason, T.G. and Blunden, G. (1989) Quaternary ammonium and tertiary sulfonium compounds of algal origin as alleviators of osmotic stress. Bot. Mar. 32, 313-316.
177. Kiene, R.P., Hoffman Williams, L.P. and Walker, J.E. (1998) Sea-water microorganisms have a high affinity glycine betaine uptake system which also recognises dimethylsulfoniopropionate. Aquat. Microb. Ecol. 15, 39-51.
178. Diaz, M.R. and Taylor, B.F. (1996) Metabolism of methylated osmolytes by aerobic bacteria from Mono Lake, a moderately hypersaline, alkaline environment. FEMS Microbiol. Ecol. 19, 239-247.
179. Smith, L.T., Pocard, J.A., Bernard, T. and Le Rudulier, D. (1988) Osmotic control of glycine betaine biosynthesis and degradation in Rhizobium meliloti. J. Bacteriol. 170, 3142-3149.
180. Caumette, P., Cohen, Y. and Matheron, R. (1991) Isolation and characterisation of Desulfovibrio halophilus sp. nov., a halophilic sulphate reducing bacterium from Solar Lake (Sinai). Syst. Appl. Microbiol. 14, 33-38.
181. Stal, L.J. and Reed, R.H. (1987) Low-molecular mass carbohydrate accumulation in cyanobacteria from a marine microbial mat in response to salt. FEMS Microbiol. Ecol. 35, 38-44.
182. King, G.M. (1988) Methanogenesis from methylated amines in a hypersaline algal mat. Appl. Environ. Microbiol. 54, 130-136.
183. Oren, A., Fischel, U., Aizenshtat, Z., Krein, E.B. and Reed, R.H. (1994) Osmotic adaptation of microbial communities in hypersaline microbial mats. In: Microbial Mats. Structure, Development and Environmental Significance (Stal, L.J. and Caumette, P., Eds.), pp. 125-130. Springer-Verlag, Berlin.
184. Ollivier, B., Caumette, P., Garcia, J-.L. and Mah, R.A. (1994) Anaerobic bacteria from hypersaline environments. Microbiol. Rev. 58, 27-38.
185. Caumette, P., Matheron, R., Welsh, D.T., Herbert, R.A. and de Wit, R. (1999) Ecology and osmoadaptation of halophilic Chromatiaceae species. In: The Phototrophic Prokaryotes (Peschek, G.A., Löffelhardt, W. and Schmetterer, G., Eds.), pp. 707-713. Kluwer Academic/Plenum Publishers, New York.
186. Welsh, D.T., Guyoneaud, R. and Caumette, P. (1998) Utilisation of compatible solutes, sucrose and trehalose by purple sulfur and non-sulfur bacteria. Can. J. Microbiol. 44, 1-6.
187. Visscher, P.T. and Van Gemerden, H. (1991) Photoautotrophic growth of Thiocapsa roseopersicina on dimethylsulfide. FEMS Microbiol. Lett. 81, 247-250.
188. Zeyer, J., Eicher, P., Wakeham, S.G. and Schwarzenbach, R.P. (1987) Oxidation of dimethyl sulfide to dimethyl sulfoxide by phototrophic bacteria. Appl. Environ. Microbiol. 53, 2026-2032.
189. Zinder, S.H. and Brock, T.D. (1978) Dimethyl sulphoxide reduction by micro-organisms. J. Gen. Microbiol. 105, 335-342.
190. Taylor, B.F. and Kiene, R.P. (1989) Microbial metabolism of dimethyl sulfide. In: Biogenic Sulfur in the Environment. Symp. Ser. 393 (Saltzman, E.S. and Cooper, W.J., Eds.), pp. 202-221. American Chemical Society, Washington, DC.
191. Jonkers, H.M., Van der Maarel, M.J.E.C., Van Gemerden, H. and Hansen, T.A. (1996) Dimethylsulfoxide reduction by marine sulfate-reducing bacteria. FEMS Microbiol. Lett. 136, 283-287.
192. Van Gemerden, H. (1993) Microbial mats: a joint venture. Mar. Geol. 113, 3-25.
193. Oren, A. (1990) Formation and breakdown of glycine betaine and trimethylamine in hypersaline environments. Antonie van Leeuwenhoek 58, 291-298.
194. Paerl, H.W., Bebout, B.M., Currin, C.A., Fitzpatrick, M.W. and Pinckney, J.L. (1993) Nitrogen fixation dynamics in microbial mats. In: Microbial Mats. Structure, Development and Environmental Significance (Stal, L.J. and Caumette, P., Eds.), pp. 325-337. Springer-Verlag, Berlin.
195. Trüper, H.G. and Galinski, E.A. (1989) Compatible solutes in halophilic phototrophic procaryotes. In: Microbial Mats. Physiological Ecology of Benthic Microbial Communities (Cohen, Y. and Rosenberg, E., Eds.), pp. 342-348. American Society for Microbiology, Washington, DC.
196. Jorgensen, B.B. (1977) Mineralization of organic matter in the sea bed: the role of sulphate reduction. Nature 296, 643-645.
197. King, G.M. (1984) Metabolism of trimethylamine, choline, and glycine betaine by sulfate-reducing and methanogenic bacteria in marine sediments. Appl. Environ. Microbiol. 48, 719-725.
198. Oremland, R.S., Marsh, L.M. and Policin, S. (1982) Methane production and simultaneous sulfate reduction in anoxic, salt marsh sediments. Nature 296, 143-145.
199. Oremland, R.S. and Policin, S. (1982) Methanogenesis and sulfate reduction: competitive and non-competitive substrates in estuarine sediments. Appl. Environ. Microbiol. 44, 1270-1276.
200. King, G.M. (1988) Distribution and metabolism of quaternary amines in marine sediments. In: Nitrogen Cycling in Coastal Marine Environments (Blackburn, T. H. and Sørensen, J., Eds.), pp. 143-173. John Wiley and Sons, Chichester.
201. Oremland, R.S. and King, G.M. (1989) Methanogenesis in hypersaline environments. In: Microbial Mats. Physiological Ecology of Benthic Microbial Communities (Cohen, Y. and Rosenberg, E., Eds.), pp. 180-190. American Society for Microbiology, Washington, DC.
202. Storey, R., Ahmed, N. and Wyn Jones, R.G. (1977) Taxonomic and ecological aspects of the distribution of glycine betaine and related compounds in plants. Oecology 27, 319-332.
203. King, G.M., Klug, M.J. and Lovely, D.R. (1983) Metabolism of acetate, methanol, and methylated amines in intertidal sediments of Lowes Cove, Maine. Appl. Environ. Microbiol. 45, 1848-1853.
204. Oremland, R.S. and Culbertson, C.W. (1992) Evaluation of methyl fluoride and dimethyl ether as inhibitors of aerobic methane oxidation. Appl. Environ. Microbiol. 58, 2983-2992.
205. Iversen, N. (1996). Methane oxidation in coastal marine environments. In: Microbiology of Atmospheric Trace Gases. Sources, Sinks and Global Change Processes (Murrell, J.C. and Kelly, D.P., Eds.), pp. 51-68. Springer-Verlag, Berlin.
206. King, G.M. (1992) Ecological aspects of methane oxidation, a key determinant of global methane dynamics. Adv. Microb. Ecol. 12, 431-468.
207. Schnell, S. and King, G.M. (1996) Response of methanotropic activity in soils and cultures to water stress. Appl. Environ. Microbiol. 62, 3203-3209.
208. Cohen, Y., Helman, Y. and Sigalevich, P. (1994) Light-driven sulfate reduction and methane emission in hypersaline cyanobacterial mats. In: Microbial Mats. Structure, Development and Environmental Significance (Stal, L.J. and Caumette, P., Eds.), pp. 421-427. Springer-Verlag, Berlin.
209. Conrad, R., Frenzel, P. and Cohen, Y. (1995) Methane emission from hypersaline microbial mats: lack of aerobic methane oxidation activity. FEMS Microbiol. Ecol. 16, 297-305.
210. Denier-VanderGon, H.A.C. and Neue, H.U. (1995) Methane emission from a wetland rice field as affected by salinity. Plant Soil 170, 307-313.
211. Giani, D., Giani, L., Cohen, Y. and Krumbein, W.E. (1985) Methanogenesis in the hyper saline Solar Lake (Sinai). FEMS Microbiol. Lett. 25, 219-224.
212. Dacey, J.W.H., King, G.M. and Wakeham, S.G. (1987) Factors controlling emission of dimethylsulphide from salt marshes. Nature 330, 643-645.
213. Edwards, D.M., Reed, R.H., Chudek, J.A., Foster, R. and Stewart, W.D.P. (1987) Organic solute accumulation in osmotically-stressed Enteromorpha intestinalis. Mar. Biol. 95, 583-592.
214. Kirst, G.O. (1996) Osmotic adjustment in phytoplankton and macroalgae: the use of dimethylsulfoniopropionate (DMSP). In: Biological and Environmental Chemistry of DMSP and Related Sulfonium Compounds (Kiene, R.P., Visscher, P.T., Keller, M.D. and Kirst, G.O., Eds.), pp. 121-129. Plemun Press, New York.
215. Steinke, M., Wolfe, G.V. and Kirst, G.O. (1998) Partial characterization of dimethylsulfoniopropionate (DMSP) lyase isoenzymes in 6 strains of Emiliana huxleyi. Mar. Ecol. Prog. Ser. 15, 39-51.
216. Taylor, B.F. and Visscher, P.T. (1996) Metabolic pathways involved in DMSP degradation. In: Biological and Environmental Chemistry of DMSP and Related Sulfonium Compounds (Kiene, R.P., Visscher, P.T., Keller, M.D. and Kirst, G.O., Eds.), pp. 265-276. Plenum Press, New York.
217. Brimblecombe, P. and Shooter, D. (1986) Photo-oxidation of dimethylsulfide in aqueous solution. Mar. Chem. 19, 343-353.
218. Smith, N.A. and Kelly, D.P. (1988) Mechanism of oxidation of dimethyl sulfide by Thiobacillus thioparus strain E6. J. Gen. Microbiol. 134, 3031-3039.
219. Visscher, P.T., Quist, P. and Van Gemerden, H. (1991) Methylated sulfur compounds in microbial mats: in situ concentrations and metabolism by colorless sulfur bacteria. Appl. Environ. Microbiol. 57, 1758-1763.
220. de Zwart, J.M.M., Nelisse, P.N. and Kuenen, J.G. (1996) Isolation and characterisation of Methylophaga sulfidovorans sp. nov.: an obligately methylotrophic, aerobic, dimethylsulfide oxidising bacterium from a microbial mat. FEMS Microbiol. Ecol. 20, 261-270.
221. Zinder, S.H. and Brock, T.D. (1978) Production of methane and carbon dioxide from methane thiol and dimethyl sulfide by anaerobic lake sediments. Nature 273, 226-228.
222. Kiene, R.P. (1988) Dimethyl sulfide metabolism in salt marsh sediments. FEMS Microbiol. Ecol. 53, 71-78.
223. Kiene, R.P. and Capone, D.G. (1988) Microbial transformations of methylated sulfur compounds in anoxic salt marsh sediments. Microb. Ecol. 15, 275-291.
224. Kiene, R.P. (1996) Microbiological controls on dimethylsulfide emissions from wetlands and the oceans. In: Microbiology of Atmospheric Trace Gases (Murrell, J.C. and Kelly, D.P., Eds.), pp. 205-225. Springer-Verlag, Berlin.
225. Taylor, B.F. and Gilchrist, D.C. (1991) New routes for aerobic biodegradation of dimethylsulfoniopropionate. Appl. Environ. Microbiol. 57, 3581-3584.
226. Oremland, R.S., Kiene, R.P., Mathrani, I., Whiticar, M.J. and Boone, D.R. (1989) Description of an estuarine methylotrophic methanogen which grows on dimethyl sulfide. Appl. Environ. Microbiol. 55, 994-1002.
227. Finster, K., Tanimoto, Y. and Bak, F. (1992) Fermentation of methanethiol and dimethylsulfide by a newly isolated methanogenic bacterium. Arch. Microbiol. 157, 425-430.
228. Van der Maarel, M.J.E.C., Jansen, M., Haanstra, R., Meijer, W.G. and Hansen, T.A. (1996) Demethylation of dimethylsulfoniopropionate to 3-S-methylmercaptopropionate by marine sulfate-reducing bacteria. Appl. Environ. Microbiol. 62, 3978-3984.
229. Kiene, R.P. and Taylor, B.F. (1988) Demethylation of dimethylsulfoniopropionate and production of thiols in anoxic marine sediments. Appl. Environ. Microbiol. 54, 2208-2212.
230. Kiene, R.P. (1992) Dynamics of dimethyl sulfide and dimethylsulfoniopropionate in oceanic water samples. Mar. Chem. 37, 29-52.
231. Visscher, P.T., Taylor, B.F. and Kiene, R.P. (1995) Microbial consumption of dimethyl sulfide and methanethiol in coastal marine sediments. FEMS Microbiol. Ecol. 18, 145-154.
232. Andreae, M.O. and Raemdonck, H. (1983) Dimethyl sulfide in the surface ocean and the marine atmosphere: A global view. Science 221, 744-747.
233. Bates, T.S., Lamb, B.K., Guenther, A., Dignon, J. and Stoiber, R.E. (1992) Sulfur emissions to the atmosphere from natural sources. J. Atmos. Chem. 14, 315-337.
234. Spiro, P.A., Jacob, D.J. and Logan, J.A. (1992) Global inventory of sulphur emissions with 1°×1° resolution. J. Geophys. Res. 97, 6023-6036.
235. Kiene, R.P. and Service, S.K. (1991) Decomposition of dissolved DMSP and DMS in estuarine waters: dependence on temperature and substrate concentration. Mar. Ecol. Prog. Ser. 76, 1-11.
236. Bates, T.S., Kiene, R.P., Wolfe, G.V., Matrai, P.A., Chavez, F.P., Buck, K.R., Blomquist, B.W. and Cuhel, R.L. (1994) The cycle of sulfur in surface seawater of the northeast Pacific. J. Geophys. Res. 99, 7835-7843.
237. Kiene, R.P. and Gerrard, G. (1995) Evaluation of glycine betaine as an inhibitor of dissolved dimethylsulphoniopropionate degradation in coastal waters. Mar. Ecol. Prog. Ser. 128, 121-131.
238. Ledyard, K.M. and Dacey, J.W.H. (1996) Microbial cycling of DMSP and DMS in coastal and oligotrophic seawater. Limnol. Oceanogr. 41, 33-40.
239. Van Duyl, F.C., Gieskes, W.W.C., Kop, W.E. and Lewis, W.E. (1998) Biological control of short-term variations in the concentration of DMSP and DMS during a Phaeocystis spring bloom. J. Sea Res. 40, 221-231.
240. Scranton, M.I. and Brewer, P.G. (1977) Occurrence of methane in the near surface waters of the western subtropical North-Atlantic. Deep Sea Res. 24, 127-138.
241. Lamontagne, R.A., Swinnerton, J.W., Linnenbom, V.J. and Smith, W.D. (1973) Methane concentrations in various marine environments. J. Geophys. Res. 78, 5317-5324.
242. Brooks, J.M., Reid, D.F. and Bernard, B.B. (1981) Methane in the upper water column of the northwestern Gulf of Mexico. J. Geophys. Res. 86, 11029-11040.
243. Burke, R.A., Reid, D.F., Brooks, J.M. and Lavoie, D.M. (1983) Upper water column methane geochemistry in the eastern tropical North Pacific. Limnol. Oceanogr. 28, 19-32.
244. Ward, B.B., Kilpatrick, K.A., Novelli, P.C. and Scranton, M.I. (1987) Methane oxidation and methane fluxes in the ocean surface layer and deep anoxic waters. Nature 327, 226-229.
245. Seifert, R., Delling, N., Richnow, H.H., Kempe, S., Hefter, J. and Michaelis, W. (1999) Ethylene and methane in the upper water column of the subtropical Atlantic. Biogeochemistry 44, 73-91.
246. Kiene, R.P. (1993) Microbial sources and sinks for methylated sulfur compounds in the marine environment. In: Microbial Growth on Cl Compounds (Murell, J.C. and Kelly, D.P., Eds.), pp. 15-33. Intercept, Andover.
247. Traganza, E.D., Swinnerton, J.W. and Cheek, C.H. (1972) Methane supersaturation and ATP-zooplankton blooms in near-surface waters of the western Mediteranean and the subtropical North Atlantic Ocean. Deep Sea Res. 26, 1237-1245.
248. Oremland, R.S. (1979) Methanogenic activity in plankton samples and fish intestines: A mechanism for in situ methanogenesis in oceanic surface waters. Limnol. Oceanogr. 24, 1136-1141.
249. Karl, D.M. and Tilbrook, B.D. (1994) Production and transport of methane in oceanic particulate organic matter. Nature 368, 732-734.
250. De Angelis, M.A. and Lee, C. (1994) Methane production during zooplankton grazing on marine phytoplankton. Limnol. Oceanogr. 39, 1298-1308.
251. Marty, D.G. (1993) Methanogenic bacteria in seawater. Limnol. Oceanogr. 38, 452-456.
252. Sieburth, J. (1994) The trophic roles of bacteria in marine ecosystems are complicated by synergistic-consortia and mixotrophic cometabolism. Progr. Oceanogr. 21, 117-128.
253. van der Maarel, M.J., Sprenger, W., Haanstra, R. and Forney, L.J. (1999) Detection of methanogenic archaea in seawater particles and the digestive tract of a marine fish species. FEMS Microbiol. Lett. 173, 189-194.
254. van der Maarel, M.J., Artz, R.R., Haanstra, R. and Forney, L.J. (1999) Association of marine archaea with the digestive tracts of two marine fish species. Appl. Environ. Microbiol. 64, 2894-2898.
255. Liss, P.S. and Slater, P.G. (1974) Flux of gases across the air-sea interface. Nature 247, 181-184.
256. Khalil, M.A.K. and Shearer, M.J. (1993) Sources of methane: An overview. In: Atmospheric Methane: Sources, Sinks and Role in Global Change (Khalil, M.A.K., Ed.), pp. 180-198. Springer-Verlag, New York.
257. Reeburgh, W.S., Whalen, S.C. and Alperin, M.J. (1993) The role of methylotrophy in the global methane budget. In: Microbial Growth on C1 Compounds (Murrell, J.C. and Kelly, D.P., Eds.), pp. 1-14. Intercept, Andover.
258. Prather, M.J., Derwent, R., Ehhalt, D., Fraser, P., Sanhueza, E. and Zhou, X. (1995) Other trace gases and atmospheric chemistry. In: Climate Change 1994 (Houghton, J.T., Meira Filho, L.J., Bruce, J., Lee, H., Callender, B.A., Haites, E., Harris, N. and Maskell, K., Eds.), pp. 73-126. Cambridge University Press, Cambridge.
259. Lovelock, J.E., Maggs, R.J. and Rasmussen, R.A. (1972) Atmospheric dimethyl sulphide and the natural sulphur cycle. Nature 237, 452-453.
260. Charlson, R.J., Lovelock, J.E., Andreae, M.O. and Warren, S.G. (1987) Oceanic phytoplankton, atmospheric sulphur, cloud albedo and climate. Nature 326, 655-661.
261. Sørensen, J. (1988) Dimethylsulfide and methane thiol in sediment porewater of a Danish estuary. Biogeochemistry 6, 201-210.
262. Steudler, P.A. and Peterson, B.J. (1984) Contribution of gaseous sulphur from salt marshes to the global sulphur cycle. Nature 311, 455-457.
263. Andreae, M.O. and Crutzen, P.J. (1997) Atmospheric aerosols: biogeochemical sources and role in atmospheric chemistry. Science 276, 1052-1058.
264. Gröne, T. and Kirst, G.O. (1992) The effect of nitrogen deficiency, methionine and inhibitors of methionine metabolism on the DMSP contents of Tetraselmis subcordiformis (Stein). Mar. Biol. 112, 85-91.
265. Keller, M.D. and Korjeff-Bellows, W. (1996) Physiological aspects of the production of dimethylsulfoniopropionate (DMSP) by marine phytoplankton. In: Biological and Environmental Chemistry of DMSP and Related Sulfonium Compounds (Kiene, R.P., Visscher, P.T., Keller, M.D. and Kirst, G.O., Eds.), pp. 131-142. Plenum Press, New York.
266. Stefels, J. and Van Boekel, W.H.M. (1993) Production of DMS from dissolved DMSP in axenic cultures of the marine phytoplankton species Phaeocystis sp. Mar. Ecol. Prog. Ser. 97, 11-18.
267. Stefels, J., Dijkhuizen, L. and Gieskes, W.C. (1995) DMSP-lyase activity in a spring phytoplankton bloom off the Dutch coast, related to Phaeocystis sp. abundance. Mar. Ecol. Prog. Ser. 123, 235-243.
268. Kiene, R.P. and Bates, T.S. (1990) Biological removal of dimethyl sulfide from sea water. Nature 345, 702-705.
269. Kiene, R.P. and Gerrard, G. (1994) Determination of trace levels of dimethylsulfoxide (DMSO) in seawater and rainwater. Mar. Chem. 47, 1-14.
270. Hatton, A.D., Malin, G., Turner, S.M. and Liss, P.S. (1996) DMSO: A significant compound in the biogeochemical cycle of DMS. In: Biological and Environmental Chemistry of DMSP and Related Sulfonium Compounds (Kiene, R.P., Visscher, P.T., Keller, M.D. and Kirst, G.O., Eds.), pp. 405-412. Plenum Press, New York.
271. Andreae, M.O. (1990) Ocean-atmosphere interactions in the global biogeochemical sulfur cycle. Mar. Chem. 30, 1-29.
272. Barnard, W.R., Andreae, M.O. and Iverson, R.L. (1984) Dimethylsulfide and Phaeocystis poucheti in the southeastern Bering sea. Cont. Shelf Res. 3, 103-113.
273. Gibson, J.A.E., Garrick, R.C., Burton, H.R. and McTaggart, A.R. (1990) Dimethylsulfide and the alga Phaeocystis pouchetti in Antarctic coastal waters. Mar. Biol. 104, 330-346.
274. Malin, G., Turner, S., Liss, P.S., Holligan, P. and Harbour, D. (1993) Dimethylsulphide and dimethylsulphoniopropionate in the Northeast Atlantic during the summer coccolithophore bloom. Deep Sea Res. 40, 1487-1508.
275. Crocker, K.M., Ondrusek, M.E., Petty, R.L. and Smith, R.C. (1995) Dimethylsulfide, algal pigments and light in an Antartic Phaeocystis sp. bloom. Mar. Biol. 124, 335-340.
276. Liss, P.S. and Mervlivat, L. (1986) Air-gas exchange rates: introduction and synthesis. In: The Role of Air-Sea Exchange in Geochemical Cycling (Buat-Menard, P., Ed.), pp. 113-127. Reidel, Dordrecht.
277. Bates, T.S., Charlson, R.J. and Gammon, R.H. (1987) Evidence for the climatic role of marine biogenic sulphur. Nature 329, 319-321.
278. Erickson, I.D.J., Ghan, S.J. and Penner, J.E. (1990) Global oceanto-atmosphere dimethyl sulfide flux. J. Geophys. Res. 95, 583-592.
279. Andreae, T.W., Andreae, M.O. and Schebeske, G. (1994) Biogenic sulfur emissions and aerosols over the tropical South Atlantic 1. Dimethylsulfide in seawater and in the atmospheric boundary layer. J. Geophys. Res. 99, 22819-22829.
280. Tarrason, L., Turner, S. and Floisand, I. (1995) Estimation of seasonal dimethyl sulfide fluxes over the North Atlantic Ocean and their contribution to European pollution levels. J. Geophys. Res. 100, 11623-11639.
281. Charlson, R.J., Schwartz, S.E., Hales, J.M., Cess, R.D., Coakley, J.J.A., Hansen, J.E. and Hofmann, D.J. (1992) Climate forcing by anthropogenic aerosols. Science 255, 423-430.
282. Turner, S.M., Malin, G., Liss, P.S., Harbour, D.S. and Holligan, P.M. (1988) The seasonal variation of dimethylsulfoniopropionate concentrations in nearshore waters. Limnol. Oceanogr. 33, 364-375.
283. Lovelock, J.E. (1995) The Ages of Gaia, 2nd edn. Oxford University Press, Oxford.
284. Ravishankara, A.R., Rudich, Y., Talukdar, R. and Barone, S.B. (1997) Oxidation of atmospheric reduced sulphur compounds: perspective from laboratory studies. Phil. Trans. R. Soc. Lond. B. 352, 171-182.
285. Legrand, M., Feniet-Saigne, C., Saltzman, E.S., Germain, C., Barkov, N.I. and Petrov, V.N. (1991) Ice-core record of oceanic emissions of dimethylsulphide during the last climate cycle. Nature 350, 144-146.
286. Hansson, M.E. and Saltzman, E.S. (1993) The first Greenland ice core record of methanesulfonate and sulfate over a full glacial cycle. Geophys. Res. Lett. 20, 1163-1166.
287. Andreae, M.O., Ferek, R.J., Bermond, F., Byrd, K.P., Engstrom, R.T., Hardin, S., Houmere, P.D., Le Marrec, F. and Raemdonck, H. (1985) Dimethyl sulfide in the surface ocean and the marine atmosphere. J. Geophys. Res. 90, 12891-12900.
288. Nguyen, B.C., Mihalopoulos, N. and Belviso, S. (1990) Seasonal variation of atmospheric dimethylsulfide at Amsterdam Island in the Southern Indian Ocean. J. Atmos. Chem. 11, 123-141.
289. Eisele, F.L. and McMurray, P.H. (1997) Recent progress in understanding particle nucleation and growth. Phil. Trans. R. Soc. Lond. B. 352, 191-201.
290. Fevek, R.J., Chatfield, R.B. and Andreae, M.O. (1986) Vertical distribution of dimethylsulphide in the marine atmosphere. Nature 320, 514-516.
291. Quinn, P.K., Covert, D.S., Bates, T.S., Kapustin, V.N., Ramsey-Bell, D.C. and McInnes, L.M. (1993) Dimethylsulfide/cloud condensation nuclei/climate system: Relevant size-resolved measurements of the chemical and physical properties of atmospheric aerosol particles. J. Geophys. Res. 98, 14863-14871.
292. Raes, F. (1995) Entrainment of free tropospheric aerosols as a regulating mechanism for cloud condensation nuclei in the remote marine boundary layer. J. Geophys. Res. 100, 2893-2903.
293. 2 acting as an intermediate. Geophys. Res. Lett. 20, 579-582.
294. Charlson, R.J. and Rodhe, H. (1982) Factors controlling the acidity of natural rainwater. Nature 295, 683-685.
295. Zhuang, G., Yi, Z., Duce, R.A. and Brown, P.R. (1992) Link between iron and sulphur cycles suggested by detection of Fe(II) in remote marine aerosols. Nature 355, 537-539.
296. Martin, J.H. and Fitzwater, S.E. (1988) Iron deficiency limits phytoplankton growth in the north-east Pacific subarctic. Nature 331, 341-343.
297. Kobler, Z.S., Barber, R.T., Coale, K.H., Fitzwater, S.E., Greene, R.M., Johnson, K.S., Lindley, S. and Falkowski, P.G. (1994) Iron limitation of phytoplankton photosynthesis in the equatorial Pacific Ocean. Nature 371, 145-149.
298. De Baar, H.J.W., De Jong, J.T.M., Bakker, D.C.E., Loscher, B.M., Veth, C., Bathmann, U. and Smetacek, V. (1995) Importance of iron for plankton blooms and carbon dioxide drawdown in the Southern Ocean. Nature 373, 412-415.
299. Kumar, N., Anderson, R.F., Mortlock, R.A., Froelich, P.N., Kubik, P., Dittrich-Hannen, B. and Suter, M. (1995) Increased biological productivity and export production in the glacial Southern Ocean. Nature 378, 675-680.
300. Lovelock, J.E. and Kump, L.R. (1994) Failure of climate regulation in a geophysical model. Nature 369, 732-734.
301. Kump, L.R. and Lovelock, J.E. (1995) The geophysiology of climate. In: Future Climates of the World. A Modelling Perspective (Henderson-Sellers, A., Ed.), pp. 537-553. Elsevier, Oxford.
302. Ayers, G.P. and Gras, J.L. (1991) Seasonal relationship between cloud condensation nuclei and aerosol methanesulphonate in marine air. Nature 353, 834-835.
303. Hegg, D.A., Ferek, R.J., Hobbs, P.V. and Radke, L.F. (1991) Dimethyl sulfide and cloud condensation nucleus correlations in the northeast Pacific Ocean. J. Geophys. Res. 96, 13189-13191.
304. Andreae, M.O., Elbert, W. and De Mora, S.J. (1995) Biogenic sulfur emissions and aerosols over the tropical South Atlantic 3. Atmospheric dimethylsulfide, aerosols and cloud condensation nuclei. J. Geophys. Res. 100, 11335-11356.
305. Leek, C. and Persson, C. (1996) Seasonal and short-term variability in dimethyl sulfide, sulfur dioxide and biogenic sulfur and seasalt aerosol particles in the arctic marine boundary layer during summer and autumn. Tellus 48B, 156-177.
306. Kiehl, J.T. and Briegleb, B.P. (1993) The relative roles of sulfate aerosols and greenhouse gases in climate forcing. Science 260, 311-314.
307. Mitchell, J.F.B., Johns, T.C., Gregory, J.M. and Tett, S.F.B. (1995) Climate response to increasing levels of greenhouse gases and sulphate aerosols. Nature 376, 501-504.
308. Caldeira, K. (1989) Evolutionary pressures on planktonic production of atmospheric sulphur. Nature 337, 732-734.
309. Martin, J.H. (1992) Iron a limiting factor in oceanic primary productivity. In: Primary Productivity and Biogeochemical Cycles in the Sea (Falkowski, P.G. and Woodhead, A.D., Eds.), pp. 123-137. Plenum Press, New York.
310. Legrand, M. (1997) Ice-core records of atmospheric sulphur. Phil. Trans. R. Soc. Lond. B. 352, 241-250.