Is the cannabinoid CB1 receptor a 2-arachidonoylglycerol receptor? Structural requirements for triggering a Ca2+ transient in NG108-15 cells

Journal of Biochemistry

Volumn 122, Issue 4, 1997, Pages 890-895

  Sugiura, Takayuki ^a   Kodaka, Tomoko ^a   Kondo, Sachiko ^a   Nakane, Shinji ^a   Kondo, Hironori ^a   Waku, Keizo ^a   Ishima, Yoshio ^b   Watanabe, Kazuhito ^c   Yamamoto, Ikuo ^c  

^a TEIKYO UNIVERSITY   (Japan)

^b Ishima Institute for Neurosciences   (Japan)

^c HOKURIKU UNIVERSITY   (Japan)

Author keywords

2 arachidonoylglycerol; Anandamide; Ca2+ transient; Cannabinoids; 9 tetrahydrocannabinol

Indexed keywords

2 ARACHIDONOYLGLYCEROL; ARACHIDONIC ACID DERIVATIVE; CALCIUM ION; CANNABINOID RECEPTOR; CANNABINOID RECEPTOR ANTAGONIST; GLYCEROL DERIVATIVE; PHOSPHOLIPASE C INHIBITOR; RECEPTOR SUBTYPE; RIMONABANT; TETRAHYDROCANNABINOL; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CONTROLLED STUDY; NONHUMAN; RAT; RECEPTOR BINDING;

ANIMALIA;

EID: 0030657922     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a021838     Document Type: Article

References (22)

1. Devane, W.A., Dysarz, F.A., III, Johnson, M.R., Melvin, L.S., and Howlett, A.C. (1988) Determination and characterization of a cannabinoid receptor in rat brain. Mol. Pharmacol. 34, 605-613
2. Herkenham, M., Lynn, A.B., Little, M.D., Johnson, M.R., Melvin, L.S., de Costa, B.R., and Rice, K.C. (1990) Cannabinoid receptor localization in brain. Proc. Natl. Acad. Sci. USA 87, 1932-1936
3. Matsuda, L.A., Lolait, S.J., Brownstein, M.J., Young, A.C., and Bonner, T.I. (1990) Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature 346, 561-564
4. Dovane, W.A., Hanus, L., Breuer, A., Pertwee, R.G., Stevenson, L.A., Griffin, G., Gibson, D., Mandelbaum, A., Etinger, A., and Mechoulam, R. (1992) Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science 258, 1946-1949
5. Sugiura, T., Kondo, S., Sukagawa, A., Tonegawa, T., Nakane, S., Yamashita, A., Ishima, Y., and Waku, K. (1996) Transacylase-mediated and phosphodiesterase-mediated synthesis of N-arachidonoylethanolamine, an endogenous cannabinoid-receptor ligand, in rat brain microsomes. Comparison with synthesis from free arachidonic acid and ethanolamine. Eur. J. Biochem. 240, 53-62
6. 2+-dependent transacylase and phosphodiesterase activities. Biochem. Biophys. Res. Commun. 218, 113-117
7. Sugiura, T., Kondo, S., Sukagawa, A., Nakane, S., Shinoda, A., Itoh, K., Yamashita, A., and Waku, K. (1995) 2-Arachidonoylglycerol: A possible endogenous cannabinoid receptor ligand in brain. Biochem. Biophys. Res. Commun. 215, 89-97
8. Mechoulam, R., Ben-Shabat, S., Hanus, L., Ligumsky, M., Kaminski, N.E., Schatz, A.R., Gopher, A., Almog, S., Martin, B.R., Compton, D.R., Pertwee, R.G., Griffin, G., Bayewitch, M., Barg, J., and Vogel, Z. (1995) Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors. Biochem. Pharmacol. 50, 83-90
9. Sugiura, T., Itoh, K., Waku, K., and Hanahan, D.J. (1994) Biological activities of N-acylethanolamine and N-acylethanolamine phosphate analogues (in Japanese). Proc. Jpn. Conf. Biochem. Lipids 36, 71-74
10. 2+ in neuroblastoma x glioma hybrid NG108-15 cells. Biochem. Biophys. Res. Commun. 229, 58-64
11. Mattson, F.H. and Volpenhein, H.A. (1962) Synthesis and properties of glycerides. J. Lipid Res. 3, 281-296
12. Bligh, E.G. and Dyer, W.J. (1959) A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol. 37, 911-917
13. Bleasdale, J.E., Thakur, N.R., Gremban, R.S., Bundy, G.L., Fitzpatrick, F.A., Smith, R.J., and Bunting, S. (1990) Selective inhibition of receptor-coupled phospholipase C-dependent processes in human platelets and polymorphonuclear neutrophils. J. Pharmacol. Exp. Ther. 255, 756-768
14. j in the inhibition of adenylate cyclase by cannabimimetic drugs. Mol. Pharmacol. 29, 307-313
15. Jin, W., Lee, N.M., Loh, H.H., and Thayer, S.A. (1994) Opioids mobilize calcium from inositol 1,4,5-trisphosphate-sensitive stores in NG108-15 cells. J. Neurosci. 14, 1920-1929
16. Clapham, D.E. and Neer, E.J. (1997) G protein βγ subunits. Annu. Rev. Pharmacol. Toxicol. 37, 167-203
17. Deadwyler, S.A., Hampson, R.E., and Childers, S.R. (1995) Functional significance of cannabinoid receptors in brain in Cannabinoid Receptors (Pertwee, R.G., ed.) pp. 205-231, Academic Press, London
18. Wartmann, M., Campbell, D., Subramanian, A., Burstein, S.H., and Davis, R.J. (1995) The MAP kinase signal transduction pathway is activated by the endogenous cannabinoid anandamide. FEBS Lett. 359, 133-136
19. Hasegawa-Sasaki, H. (1985) Early changes in inositol lipids and their metabolites induced by platelet-derived growth factor in quiescent Swiss mouse 3T3 cells. Biochem. J. 232, 99-109
20. Gammon, C.M., Allen, A.C., and Morell, P. (1989) Bradykinin stimulates phosphoinositide hydrolysis and mobilization of arachidonic acid in dorsal root ganglion neurons. J. Neurochem. 53, 95-101
21. Prescott, S.M. and Majerus, P.W. (1983) Characterization of 1,2-diacylglycerol hydrolysis in human platelets. Demonstration of an arachidonoyl-monoacylglycerol intermediate. J. Biol. Chem. 258, 764-769
22. Bisogno, T., Sepe, N., Melck, D., Maurelli, S., De Petrocellis, L., and Di Marzo, V. (1997) Biosynthesis, release and degradation of the novel endogenous cannabimimetic metabolite 2-arachidonoylglycerol in mouse neuroblastoma cells. Biochem. J. 322, 671-677