Suppressors of cytokine signaling-1 and -6 associate with and inhibit the insulin receptor: A potential mechanism for cytokine-mediated insulin resistance

Journal of Biological Chemistry

Volumn 276, Issue 28, 2001, Pages 25889-25893

  Mooney, Robert A ^a   Senn, Joseph ^a   Cameron, Scott ^a   Inamdar, Nilufar ^a   Boivin, Laurie M ^a   Shang, Yuhua ^a   Furlanetto, Richard W ^a,b  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^b Box 777 ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; INSULIN; PROTEINS; TUMORS;

INSULIN RECEPTORS (IR); INSULIN RESISTANCE;

BIOCHEMISTRY;

CYTOKINE; GROWTH HORMONE; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; INTERLEUKIN 1BETA; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN KINASE B; SCOS PROTEIN; SOCS 6 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; REPRESSOR PROTEIN;

ANIMAL CELL; ARTICLE; ATHEROSCLEROSIS; AUTOPHOSPHORYLATION; CELL STRAIN HEPG2; CONTROLLED STUDY; GENE OVEREXPRESSION; HYPERTENSION; INSULIN RECEPTOR SIGNALING; INSULIN RESISTANCE; INSULIN TREATMENT; METABOLIC DISORDER; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; RAT; SIGNAL TRANSDUCTION; CELL LINE; HUMAN; PHYSIOLOGY;

ANIMALIA;

CELL LINE; HUMANS; INSULIN; INSULIN RESISTANCE; RECEPTOR, INSULIN; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION;

EID: 0035854723     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M010579200     Document Type: Article

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