Kainate receptor-mediated apoptosis in primary cultures of cerebellar granule cells is attenuated by mitogen-activated protein and cyclin-dependent kinase inhibitors

British Journal of Pharmacology

Volumn 135, Issue 7, 2002, Pages 1733-1742

  Giardina, Sarah F ^a   Beart, Philip M ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

Apoptosis; Cerebellar granule cells; Cyclin dependent kinases; Excitotoxicity; Kainate; MAP kinases; MEK; P38 MAP Kinase

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CYCLIN DEPENDENT KINASE INHIBITOR; DNA FRAGMENT; DNA NUCLEOTIDYLEXOTRANSFERASE; KAINIC ACID; KAINIC ACID RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; OLOMOUCINE; ROSCOVITINE; CYCLIN DEPENDENT KINASE; ENZYME INHIBITOR; PROTEIN KINASE INHIBITOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL VIABILITY; CEREBELLUM; CONCENTRATION RESPONSE; CONTROLLED STUDY; GRANULE CELL; NERVE CELL NECROSIS; NEUROTOXICITY; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; ANIMAL; CELL CULTURE; CEREBELLUM CORTEX; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; MOUSE; PHYSIOLOGY; TOXICITY AND INTOXICATION;

ANIMALS; APOPTOSIS; CELLS, CULTURED; CEREBELLAR CORTEX; CYCLIN-DEPENDENT KINASES; ENZYME INHIBITORS; KAINIC ACID; MICE; NEUROTOXICITY SYNDROMES; PROTEIN KINASE INHIBITORS; RECEPTORS, KAINIC ACID;

EID: 0036550271     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704636     Document Type: Article

References (55)

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