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Volumn 20, Issue 13, 2000, Pages 5037-5044

Role of p38 mitogen-activated protein kinase in axotomy-induced apoptosis of rat retinal ganglion cells

Author keywords

Apoptosis; Axotomy; Glutamate; Mitogen activated protein kinase; NMDA; Optic nerve; p38; Retinal ganglion cells

Indexed keywords

GLUTAMIC ACID; MITOGEN ACTIVATED PROTEIN KINASE; N METHYL DEXTRO ASPARTIC ACID;

EID: 0034235663     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.20-13-05037.2000     Document Type: Article
Times cited : (196)

References (55)
  • 1
    • 0020653177 scopus 로고
    • A potential for axonal regeneration in neurons of the adult mammalian nervous system
    • Aguayo AJ, Benfey M, David S (1983) A potential for axonal regeneration in neurons of the adult mammalian nervous system. Birth Defects Orig Artie Ser 19:327-340.
    • (1983) Birth Defects Orig Artie Ser , vol.19 , pp. 327-340
    • Aguayo, A.J.1    Benfey, M.2    David, S.3
  • 3
    • 0030426902 scopus 로고    scopus 로고
    • Pharmacological profile of SB 203580, a selective inhibitor of cytokine suppressive binding protein/p38 kinase, in animal models of arthritis, hone resorption, endotoxin shock and immune function
    • Badger AM, Bradheer JN, Votla B, Lee Jf, Adams JL, Griswold DP, (1996) Pharmacological profile of SB 203580, a selective inhibitor of cytokine suppressive binding protein/p38 kinase, in animal models of arthritis, hone resorption, endotoxin shock and immune function. J Pharmacol Exp Ther 274:1453-1461.
    • (1996) J Pharmacol Exp Ther , vol.274 , pp. 1453-1461
    • Badger, A.M.1    Bradheer, J.N.2    Votla, B.3    Jf, L.4    Adams, J.L.5    Griswold, D.P.6
  • 4
    • 0028310855 scopus 로고
    • Axo-tomy results in delayed death and apoptosis of retinal ganglion cells in aduit rats
    • Berkelaar M. Clarke DB, Wang YC. Bray GM. Aguayo AJ (1994) Axo-tomy results in delayed death and apoptosis of retinal ganglion cells in aduit rats. J Neurosci 14:4368-4374.
    • (1994) J Neurosci , vol.14 , pp. 4368-4374
    • Berkelaar, M.1    Clarke, D.B.2    Wang, Y.C.3    Bray, G.M.4    Aguayo, A.J.5
  • 5
    • 0029153913 scopus 로고
    • Apoptosis and necrosis: Two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/ superoxide in cortical cell cultures
    • Bonfoco E, Kraine D. Ankarcrona M, Nieotera P. Lipton SA (1995) Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/ superoxide in cortical cell cultures. Proc Natl Acad Sci USA 92:7162-7166.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 7162-7166
    • Bonfoco, E.1    Kraine, D.2    Ankarcrona, M.3    Nieotera, P.4    Lipton, S.A.5
  • 6
    • 0028926263 scopus 로고
    • Parallel signal processing among mammalian MAPKs
    • Cano E, Muhadevan LC (1995) Parallel signal processing among mammalian MAPKs. Trends Biochem Sci 20:117-122.
    • (1995) Trends Biochem Sci , vol.20 , pp. 117-122
    • Cano, E.1    Muhadevan, L.C.2
  • 7
    • 0033581318 scopus 로고    scopus 로고
    • Inhibition of mitogen-activated protein kinases protect axotomized developing neurons
    • Castagné, Clarke PGH (1999) Inhibition of mitogen-activated protein kinases protect axotomized developing neurons. Brain Res 842:215-219.
    • (1999) Brain Res , vol.842 , pp. 215-219
    • Castagné1    Clarke, P.G.H.2
  • 8
    • 0029043582 scopus 로고
    • How MAP kinases are regulated
    • Cobb MH, Goldsmith EJ (1995) How MAP kinases are regulated. J Biol Them 270:14843-14846.
    • (1995) J Biol Them , vol.270 , pp. 14843-14846
    • Cobb, M.H.1    Goldsmith, E.J.2
  • 9
    • 0028988138 scopus 로고
    • SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1
    • Cuenda A, Rouse J. Doza YN. Mcier R. Cohen P. Gallagher TF. Young PR. Lee JC (1995) SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1. FEBS Lett 364:229-233.
    • (1995) FEBS Lett , vol.364 , pp. 229-233
    • Cuenda, A.1    Rouse, J.2    Doza, Y.N.3    Mcier, R.4    Cohen, P.5    Gallagher, T.F.6    Young, P.R.7    Lee, J.C.8
  • 10
    • 0031024646 scopus 로고    scopus 로고
    • Activation of stress-activated protein kinase-3 (SAPK3) by cytokines and cellular stresses is mediated via SAPKK3 (MKK6); comparison of the specificities of SAPK3 and SAPK2 (RK/p38)
    • Cuenda A, Coben P, Buee-Scherrer V, Gliedert M (1997) Activation of stress-activated protein kinase-3 (SAPK3) by cytokines and cellular stresses is mediated via SAPKK3 (MKK6); comparison of the specificities of SAPK3 and SAPK2 (RK/p38). EMBO J 16:295-305.
    • (1997) EMBO J , vol.16 , pp. 295-305
    • Cuenda, A.1    Coben, P.2    Buee-Scherrer, V.3    Gliedert, M.4
  • 12
    • 0033608134 scopus 로고    scopus 로고
    • New perspectives on glaucoma
    • Dreyer F.B. Lipton SA (1999) New perspectives on glaucoma. JAMA 281:306-308.
    • (1999) JAMA , vol.281 , pp. 306-308
    • Dreyer, F.B.1    Lipton, S.A.2
  • 13
    • 0028918483 scopus 로고
    • Transcriptional or translational inhibition blocks low dose NMDA-mcdiatcd cell death
    • Dreyer EB, Zhang D, Lipton SA (1995) Transcriptional or translational inhibition blocks low dose NMDA-mcdiatcd cell death. NcuroReport 6:442-944.
    • (1995) NcuroReport , vol.6 , pp. 442-944
    • Dreyer, E.B.1    Zhang, D.2    Lipton, S.A.3
  • 14
  • 15
    • 0033582521 scopus 로고    scopus 로고
    • Role of interferon regulatory factor-1 and mitogen-activated protein kinase pathways in the induction of nitric oxide synthase-2 in retinal pigmented epithelial cells
    • Faure V, Hecquet C, Courtois Y, Goureau O (1999) Role of interferon regulatory factor-1 and mitogen-activated protein kinase pathways in the induction of nitric oxide synthase-2 in retinal pigmented epithelial cells. J Biol Chem 274:4794-4800.
    • (1999) J Biol Chem , vol.274 , pp. 4794-4800
    • Faure, V.1    Hecquet, C.2    Courtois, Y.3    Goureau, O.4
  • 16
    • 0028015872 scopus 로고
    • Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of Hsp27
    • Freshncy NW, Rawlinson L, Guesdon F, Jones E, Cowlcy S, Hsuan J, Saklatvala J (1994) Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of Hsp27, Cell 78:1039-1049.
    • (1994) Cell , vol.78 , pp. 1039-1049
    • Freshncy, N.W.1    Rawlinson, L.2    Guesdon, F.3    Jones, E.4    Cowlcy, S.5    Hsuan, J.6    Saklatvala, J.7
  • 18
    • 0027936755 scopus 로고
    • A MAP kinase targeted by endotoxin and hypcrosmolarity in mammalian cells
    • Han J. Lee JD. Bibbs L, Ulevitch RJ (1994) A MAP kinase targeted by endotoxin and hypcrosmolarity in mammalian cells. Science 265:808-811.
    • (1994) Science , vol.265 , pp. 808-811
    • Han, J.1    Lee, J.D.2    Bibbs, L.3    Ulevitch, R.J.4
  • 19
    • 0032919249 scopus 로고
    • An inhibitor of p38 and JNK MAP kinases prevents activation of caspase and apoptosis of cultured cerebellar granule neurons
    • Harada J, Sugimolo M (1949) An inhibitor of p38 and JNK MAP kinases prevents activation of caspase and apoptosis of cultured cerebellar granule neurons. Jpn J Pharmacol 79:369-378.
    • (1949) Jpn J Pharmacol , vol.79 , pp. 369-378
    • Harada, J.1    Sugimolo, M.2
  • 20
    • 0032524763 scopus 로고    scopus 로고
    • Inhibitors of p38 mitogen-aetivaled protein kinase promote neuronal survival in vitro
    • Horstmann S. Kahle PJ, Borasio GD (1998) Inhibitors of p38 mitogen-aetivaled protein kinase promote neuronal survival in vitro. J Neurosci Res 52:483-490.
    • (1998) J Neurosci Res , vol.52 , pp. 483-490
    • Horstmann, S.1    Kahle, P.J.2    Borasio, G.D.3
  • 21
    • 0018427872 scopus 로고
    • A schematic eye for the rat
    • Hughes A (1979) A schematic eye for the rat. Vision Res 19:569-588.
    • (1979) Vision Res , vol.19 , pp. 569-588
    • Hughes, A.1
  • 22
    • 0030851891 scopus 로고    scopus 로고
    • Up-regulation of Bax protein in degenerating retinal ganglion cells precedes apoptotic cell death after optic nerve lesion in the rat
    • Isenmann S. Wahl C. Krajews'ki S. Reed JC, Bähr M (1997) Up-regulation of Bax protein in degenerating retinal ganglion cells precedes apoptotic cell death after optic nerve lesion in the rat. Eur J Neurosci 9:1763-1772.
    • (1997) Eur J Neurosci , vol.9 , pp. 1763-1772
    • Isenmann, S.1    Wahl, C.2    Krajews'ki, S.3    Reed, J.C.4    Bähr, M.5
  • 23
    • 0029982565 scopus 로고    scopus 로고
    • Characterization of the structure and function of a new mitogen-activated protein kinase (p38beta)
    • Jiang Y, Chen C. Li Z, Guo W. Gegner JA. Lin S, Han J (1996) Characterization of the structure and function of a new mitogen-activated protein kinase (p38beta). J Biol Chem 271:17920-17926.
    • (1996) J Biol Chem , vol.271 , pp. 17920-17926
    • Jiang, Y.1    Chen, C.2    Li, Z.3    Guo, W.4    Gegner, J.A.5    Lin, S.6    Han, J.7
  • 24
    • 0030828701 scopus 로고    scopus 로고
    • Characterization of the structure and function of the fourth member of p38 group mitogen-activated protein kinases. p38delta
    • Jiang Y. Gram H, Zhao M. New L. Gu J. Feng L, Di Padova F. Ulevitch RJ, Han J (1997) Characterization of the structure and function of the fourth member of p38 group mitogen-activated protein kinases. p38delta. J Biol Chem 272:30122-30128.
    • (1997) J Biol Chem , vol.272 , pp. 30122-30128
    • Jiang, Y.1    Gram, H.2    Zhao, M.3    New, L.4    Gu, J.5    Feng, L.6    Di Padova, F.7    Ulevitch, R.J.8    Han, J.9
  • 25
    • 0030741894 scopus 로고    scopus 로고
    • Activation and involvement of p38 mitogen-activated protein kinase in glutamate-induced apoptosis in rat cerebellar granule cells
    • Kawasaki H, Morooka T. Shimohama S. Kimura J, Hirano T. Gotoh Y, Nishula F. (1997) Activation and involvement of p38 mitogen-activated protein kinase in glutamate-induced apoptosis in rat cerebellar granule cells. J Biol Chem 272:18518-18521.
    • (1997) J Biol Chem , vol.272 , pp. 18518-18521
    • Kawasaki, H.1    Morooka, T.2    Shimohama, S.3    Kimura, J.4    Hirano, T.5    Gotoh, Y.6    Nishula, F.7
  • 26
    • 0344333441 scopus 로고    scopus 로고
    • Inhibition of CPP32-like proteases rescues axotomized retinal ganglion cells from secondary cell death in vivo
    • Kcrrner P. Klocker N. Labes M. Bähr M (1998) Inhibition of CPP32-like proteases rescues axotomized retinal ganglion cells from secondary cell death in vivo. J Neurosci 18:4656-4662.
    • (1998) J Neurosci , vol.18 , pp. 4656-4662
    • Kcrrner, P.1    Klocker, N.2    Labes, M.3    Bähr, M.4
  • 27
    • 0030709339 scopus 로고    scopus 로고
    • In vivo neurotrophic effects of GDNF on axotomized retinal ganglion cells
    • K locker N. Braunling F, Isenmann S, Bähr M (1997) In vivo neurotrophic effects of GDNF on axotomized retinal ganglion cells. Neuro-Report 8:3439-3442.
    • (1997) Neuro-Report , vol.8 , pp. 3439-3442
    • Klocker, N.1    Braunling, F.2    Isenmann, S.3    Bähr, M.4
  • 28
    • 0032078286 scopus 로고    scopus 로고
    • Effects of GDNF on retinal ganglion cell survival following axotomy
    • Koeberle PD, Ball AK (1998) Effects of GDNF on retinal ganglion cell survival following axotomy. Vision Res 38:1505-1515.
    • (1998) Vision Res , vol.38 , pp. 1505-1515
    • Koeberle, P.D.1    Ball, A.K.2
  • 29
    • 0030808984 scopus 로고    scopus 로고
    • Apoptosis induced by withdrawal of trophic factors is mediated by p38 mitogen-activated protein kinasc
    • Kummer JL, Rao PK. Heidenreich KA (1997) Apoptosis induced by withdrawal of trophic factors is mediated by p38 mitogen-activated protein kinasc. J Biol Chem 272:20490-20494.
    • (1997) J Biol Chem , vol.272 , pp. 20490-20494
    • Kummer, J.L.1    Rao, P.K.2    Heidenreich, K.A.3
  • 32
    • 0021365377 scopus 로고
    • Monoclonal antibody to Thy-1 enhances regeneration of processes by rat retinal ganglion cells in culture
    • Lcifer D. Lipton SA, Barnstable CJ, Masland RH (1984) Monoclonal antibody to Thy-1 enhances regeneration of processes by rat retinal ganglion cells in culture. Science 224:303-306.
    • (1984) Science , vol.224 , pp. 303-306
    • Lcifer, D.1    Lipton, S.A.2    Barnstable, C.J.3    Masland, R.H.4
  • 33
    • 0030581626 scopus 로고    scopus 로고
    • The primary structure of p38 gamma: A new member of p38 group of MAP kinases
    • Li Z, Jiang Y, Ulevitch RJ, Ran J (1996) The primary structure of p38 gamma: a new member of p38 group of MAP kinases. Biochem Biophys Res Commun 228:334-340.
    • (1996) Biochem Biophys Res Commun , vol.228 , pp. 334-340
    • Li, Z.1    Jiang, Y.2    Ulevitch, R.J.3    Ran, J.4
  • 34
    • 84948011844 scopus 로고
    • The toxic effect of sodium 1-glutamate on the inner layers of the retina
    • Lucas DR. Newhousc JP (1957) The toxic effect of sodium 1-glutamate on the inner layers of the retina. Arch Ophthalmol 58:193-201.
    • (1957) Arch Ophthalmol , vol.58 , pp. 193-201
    • Lucas, D.R.1    Newhousc, J.P.2
  • 35
    • 0027522462 scopus 로고
    • Intravitreal injections of neurotrophic factors support the survival of axotomized retinal ganglion cells in adult rats in vivo
    • Mey J, Thanos S (1993) Intravitreal injections of neurotrophic factors support the survival of axotomized retinal ganglion cells in adult rats in vivo. Brain Res 602:304-317.
    • (1993) Brain Res , vol.602 , pp. 304-317
    • Mey, J.1    Thanos, S.2
  • 36
    • 0033525762 scopus 로고    scopus 로고
    • Glutamate receptor signaling interplay modulates stress-sensitive mitogen-activated protein kinases and neuronal cell death
    • Mukherjec PK, DeCoster MA, Campbell FZ, Davis RJ, Bazan NG (1999) Glutamate receptor signaling interplay modulates stress-sensitive mitogen-activated protein kinases and neuronal cell death. J Biol Chem 274:6493-6498.
    • (1999) J Biol Chem , vol.274 , pp. 6493-6498
    • Mukherjec, P.K.1    DeCoster, M.A.2    Campbell, F.Z.3    Davis, R.J.4    Bazan, N.G.5
  • 37
    • 0029979673 scopus 로고    scopus 로고
    • Effects of axotomy and intraocular administration of NT-4, NT-3, and brain-derived neurotrophic factor on the survival of adult rat retinal ganglion cells. A quantitative in vivo study
    • Peinado-Ramon P, Salvador M. Villegas-Perez MP, Vidal-Sanz M (1996) Effects of axotomy and intraocular administration of NT-4, NT-3, and brain-derived neurotrophic factor on the survival of adult rat retinal ganglion cells. A quantitative in vivo study. Invest Ophthalmol Vis Sci 37:489-500.
    • (1996) Invest Ophthalmol Vis Sci , vol.37 , pp. 489-500
    • Peinado-Ramon, P.1    Salvador, M.2    Villegas-Perez, M.P.3    Vidal-Sanz, M.4
  • 38
    • 0019420573 scopus 로고
    • Evidence for an amacrine cell system in the ganglion cell layer of the rat retina
    • Perry VH (1981) Evidence for an amacrine cell system in the ganglion cell layer of the rat retina. Neuroscicnce 6:931-944.
    • (1981) Neuroscicnce , vol.6 , pp. 931-944
    • Perry, V.H.1
  • 39
    • 0020524994 scopus 로고
    • Postnatal changes in retinal ganglion cell and optic axon populations in the pigmented rat
    • Perry VH, Henderson Z, Linden R (1983) Postnatal changes in retinal ganglion cell and optic axon populations in the pigmented rat. J Comp Neurol 219:356-368.
    • (1983) J Comp Neurol , vol.219 , pp. 356-368
    • Perry, V.H.1    Henderson, Z.2    Linden, R.3
  • 40
    • 0028935270 scopus 로고
    • Pro-inflammatory cytokincs and environmental stress cause p38 mitogen- Activated protein kinase activation by dual phosphorylation on tyrosine and threonine
    • Raingcaud J, Gupta S, Rogers JS. Dickens M, Han J, Ulevitch RJ, Davis RJ (1995) Pro-inflammatory cytokincs and environmental stress cause p38 mitogen- activated protein kinase activation by dual phosphorylation on tyrosine and threonine. J Biol Chem 270:7420-7426.
    • (1995) J Biol Chem , vol.270 , pp. 7420-7426
    • Raingcaud, J.1    Gupta, S.2    Rogers, J.S.3    Dickens, M.4    Han, J.5    Ulevitch, R.J.6    Davis, R.J.7
  • 41
    • 0028022750 scopus 로고
    • A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinasc-2 and phosphorylation of the small heat shock proteins
    • Rouse J, Cohen P, Trigon S, Morange M, Alonso-Llamazares A, Zamanillo D, Hunt T, Ncbrcda AR (1994) A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinasc-2 and phosphorylation of the small heat shock proteins. Cell 78:1027-1037.
    • (1994) Cell , vol.78 , pp. 1027-1037
    • Rouse, J.1    Cohen, P.2    Trigon, S.3    Morange, M.4    Alonso-Llamazares, A.5    Zamanillo, D.6    Hunt, T.7    Ncbrcda, A.R.8
  • 42
    • 0029783969 scopus 로고    scopus 로고
    • Factors affecting the survival of cat retinal ganglion cells after optic nerve injury
    • Russelakis-Carneiro M, Silveira LC, Perry VH (1996) Factors affecting the survival of cat retinal ganglion cells after optic nerve injury. J Neurocytol 25:393-402.
    • (1996) J Neurocytol , vol.25 , pp. 393-402
    • Russelakis-Carneiro, M.1    Silveira, L.C.2    Perry, V.H.3
  • 43
    • 0027464886 scopus 로고
    • Treatment of the adult retina with microglia-suppressing factors retards axotomy-induccd neuronal degradation and enhances axonal regeneration in vivo and in vitro
    • Thanos S, Mey J. Wild M (1993) Treatment of the adult retina with microglia-suppressing factors retards axotomy-induccd neuronal degradation and enhances axonal regeneration in vivo and in vitro. J Neurosci 13:455-466.
    • (1993) J Neurosci , vol.13 , pp. 455-466
    • Thanos, S.1    Mey, J.2    Wild, M.3
  • 44
    • 0026670221 scopus 로고
    • Specific transcellular staining of microglia in the adult rat after traumatic degeneration of carhocyaninc-fillcd retinal ganglion cells
    • Thanos S, Pavlidis C, Mey J, Thiel HJ (1992) Specific transcellular staining of microglia in the adult rat after traumatic degeneration of carhocyaninc-fillcd retinal ganglion cells, Exp Eye Res 55:101-117.
    • (1992) Exp Eye Res , vol.55 , pp. 101-117
    • Thanos, S.1    Pavlidis, C.2    Mey, J.3    Thiel, H.J.4
  • 45
    • 0023857355 scopus 로고
    • Influences of peripheral nerve grafts on the survival and regrowth of axotomized retinal ganglion cells in adult rats
    • Villcgas-Perez MP, Vidal-Sanz M, Bray GM, Aguayo AJ (1988) Influences of peripheral nerve grafts on the survival and regrowth of axotomized retinal ganglion cells in adult rats. J Neurosci 8:265-280.
    • (1988) J Neurosci , vol.8 , pp. 265-280
    • Villcgas-Perez, M.P.1    Vidal-Sanz, M.2    Bray, G.M.3    Aguayo, A.J.4
  • 46
    • 0027463379 scopus 로고
    • Rapid and protracted phases of retinal ganglion cell loss follow axotomy in the optic nerve of adult rats
    • Villegas-Perez MP, Vidal-Sanz M. Rasminsky M, Bray GM, Aguayo AJ (1993) Rapid and protracted phases of retinal ganglion cell loss follow axotomy in the optic nerve of adult rats. J Neurohiol 24:23-36.
    • (1993) J Neurohiol , vol.24 , pp. 23-36
    • Villegas-Perez, M.P.1    Vidal-Sanz, M.2    Rasminsky, M.3    Bray, G.M.4    Aguayo, A.J.5
  • 47
    • 0031959242 scopus 로고    scopus 로고
    • Neurotransmitter regulation of MAP kinasc signaling in striatal neurons in primary culture
    • Vincent SR, Sehhen M, Dumuis A. Bockacrt J (1998) Neurotransmitter regulation of MAP kinasc signaling in striatal neurons in primary culture. Synapse 29:29-36.
    • (1998) Synapse , vol.29 , pp. 29-36
    • Vincent, S.R.1    Sehhen, M.2    Dumuis, A.3    Bockacrt, J.4
  • 49
    • 0032776942 scopus 로고    scopus 로고
    • An experimental basis for implicating cxcitotoxicity in glaucomatous optic neuropathy
    • Vorwerk CK. Gorla MS, Dreyer EB (1999b) An experimental basis for implicating cxcitotoxicity in glaucomatous optic neuropathy. Surv Ophthalmol S142-S150.
    • (1999) Surv Ophthalmol
    • Vorwerk, C.K.1    Gorla, M.S.2    Dreyer, E.B.3
  • 53
    • 0032943670 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic factor (GDNF) promotes the survival of axotomized retinal ganglion cells in adult rats: Comparison to and combination with brain-derived neurotrophic factor (BDNF)
    • Yan Q, Wang J, Matheson CR, Urich JL (1999) Glial cell line-derived neurotrophic factor (GDNF) promotes the survival of axotomized retinal ganglion cells in adult rats: comparison to and combination with brain-derived neurotrophic factor (BDNF). J Neurobiol 38:382-390.
    • (1999) J Neurobiol , vol.38 , pp. 382-390
    • Yan, Q.1    Wang, J.2    Matheson, C.R.3    Urich, J.L.4
  • 54
    • 0031789649 scopus 로고    scopus 로고
    • Elevation of intraocular glutamate levels in rats with partial lesion of the optic nerve
    • Yolcs E. Schwanz M (1998) Elevation of intraocular glutamate levels in rats with partial lesion of the optic nerve, Arch Ophthalmol 116:906-910.
    • (1998) Arch Ophthalmol , vol.116 , pp. 906-910
    • Yolcs, E.1    Schwanz, M.2
  • 55
    • 0030866842 scopus 로고    scopus 로고
    • NMDA-reccptor antagonist protects neurons from secondary degeneration after partial optic nerve crush
    • Yolcs E, Muller S, Schwartz M (1997) NMDA-reccptor antagonist protects neurons from secondary degeneration after partial optic nerve crush. J Ncurotrauma 14:665-675.
    • (1997) J Ncurotrauma , vol.14 , pp. 665-675
    • Yolcs, E.1    Muller, S.2    Schwartz, M.3


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