Contribution of NF-κB and p53 in the glutamate-induced apoptosis

International Journal of Developmental Neuroscience

Volumn 18, Issue 4-5, 2000, Pages 447-454

  Uberti, Daniela ^a   Grilli, Mariagrazia ^a   Memo, Maurizio ^a  

^a UNIVERSITY OF BRESCIA   (Italy)

Author keywords

Aging; Cerebellar neurons; Cyclin dependent kinase; Excitotoxicity; Glutamate; Neurodegenerative diseases; Tumour suppressor gene

Indexed keywords

CYCLIN DEPENDENT KINASE; GLUTAMIC ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NEUROTOXIN; PROTEIN P53; CYTOKINE; GLUTAMATE RECEPTOR; OXYGEN RADICAL;

AGING; ANIMAL; APOPTOSIS; ARTICLE; CELL CULTURE; CEREBELLUM; CHEMICALLY INDUCED DISORDER; CYTOLOGY; DNA DAMAGE; DRUG EFFECT; ENZYMOLOGY; METABOLISM; NERVE CELL; NERVE DEGENERATION; PHYSIOLOGY; RAT; SPRAGUE DAWLEY RAT; TUMOR SUPPRESSOR GENE; ANIMAL CELL; CELL CYCLE; CONTROLLED STUDY; DEGENERATIVE DISEASE; GRANULE CELL; IMMUNOREACTIVITY; NONHUMAN; PRIORITY JOURNAL; REVIEW;

AGING; ANIMALS; APOPTOSIS; CELLS, CULTURED; CEREBELLUM; CYCLIN-DEPENDENT KINASES; DNA DAMAGE; GENES, TUMOR SUPPRESSOR; GLUTAMIC ACID; NERVE DEGENERATION; NEURONS; NEUROTOXINS; NF-KAPPA B; RATS; RATS, SPRAGUE-DAWLEY; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0034214879     PISSN: 07365748     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0736-5748(00)00018-6     Document Type: Article

References (65)

1. Abbadie C., Kabrun N., Bouali F., Smardova J., Stehelin D., Vandenbender B., Enrietto P.J. High levels of c-rel expression are associated with programmed cell death in the developing avian embryo and in bone marrow cells in vitro. Cell. 75:1993;899-912.
2. Atwood W.J., Tornatore C.S., Traub R., Conant K., Drew P.D., Major E.O. Stimulation of HIV type 1 gene expression and induction of NF-kappa B (p50/p65)-binding activity in tumor necrosis factor alpha-treated human fetal glial cells. AIDS Res. Hum. Retroviruses. 1:1994;1207-1211.
3. Baichwal M., Baeuerle P.A. Activate NF-kappa B or die? Curr. Biol. 7:1997;94-96.
4. Belloni, M., Uberti, D., Rizzini, C. and Memo, M., Kainic acid activation of the DNA mismatch repair protein MSH2 in rat brain, 1999, 94, 1323-1331.
5. Belloni M., Uberti D., Rizzini C., Jiricny J., Memo M. Induction of two DNA mismatch reair proteins, MSH2 and MSH6, in differentiated human neuroblastoma SH-SY5Y cells exposed to doxorubicin. J. Neurochem. 72:1999;974-979.
6. Birge S.J. Hormones and the aging brain. Geriatrics. 53:(1):1998;S28-S30.
7. Chen J., Nagayama T., Jin K., Stetler R.A., Zhu R.L., Graham S.H., Simon R.P. Induction of caspase-3-like protease may mediate delayed neuronal death in the hippocampus after transient cerebral ischemia. J. Neurosci. 18:1998;4914-4928.
8. Choi D.W. Glutamate neurotoxicity and diseases of the neurons system. Neuron. 1:1988;623-634.
9. Chopp M., Li Y., Zhang Z.G., Freytag S.O. p53 expression in brain after middle cerebral artery occlusion in the rat. Biochem. Biophys. Res. Commun. 182:1992;1201-1207.
10. Clarke P.G., Posada A., Primi M.P., Castagne V. Neuronal death in the central nervous system during development. Biomed. Pharmacother. 52:1998;356-362.
11. Clemens J.A., Stephenson D.T., Yin T., Smalstig E.R., Panetta J.A., Little S. Drug-induced neuroprotection from global ischemia is associated with prevention of persistent but not transient activation of nuclear factor-κB in rats. Stroke. 29:1998;677-682.
12. Dollard S.C., James H.J., Sharer L.R., Epstein L.G., Gelbard H.A., Dewourst S. Activation of nuclear factor-kappa B in brains from children with HIV-1 encephalitis. Neuropathol. Appl. Neurobiol. 21:1995;518-528.
13. Eizenberg O., Faber-Elman A., Gottlier E., Oren M., Rotter V., Schwartz M. p53 plays a regulatory role in differentiation and apoptosis of central nervous system-associated cells. Mol. Cell Biol. 16:1996;5178-5185.
14. El-Deiry W.S., Tokino T., Veculescu V.E., Levy D.B., Parsons R., Trent J.M., Lin D., Mecer W.E., Kinzler K.W., Vogelstein B. WAF1, a potent mediator of p53 tumor suppression. Cell. 75:1993;817-825.
15. Enokido Y., Araki T., Tanaka K., Hatanaka H. Involvement of p53 in DNA strand break-induced apoptosis in postmitotic CNS neurons. Eur. J. Neurosci. 8:1996;1812-1821.
16. Ferger B., Spratt C., Teismann P., Seitz G., Kuschinsky K. Effects of cytisine on hydroxyl radicals in vitro and MPTP-induced dopamine depletion in vivo. Eur. J. Pharmacol. 360:1999;155-163.
17. Grilli M., Goffi F., Memo M., Spano P.F. Interleukin-1 and glutamate activate the NF-κB/Rel binding site from the regulatory region of the amyloid precursor protein gene in primary neuronal cultures. J. Biol. Chem. 271:1996;15002-15007.
18. Grilli M., Pizzi M., Memo M., Spano P.F. Neuroprotection by salicylate through blockade of NF-κB activation. Science. 274:1996;1383-1385.
19. Grilli M., Memo M. NF-κB/Rel proteins: a point of convergence of signalling pathways relevant in neuronal function and dysfunction. Biochem. Pharmacol. 57:1999;1-7.
20. Grilli M., Memo M. Possible role of NF-κB and p53 in glutamate-induced pro-apoptotic neuronal pathway. Cell Death and Diff. 6:1999;22-27.
21. Grimm S., Bauer M.K., Baeuerle P.A., Shulze-Osthoff B. Bcl-2 down-regulates the activity of transcription factor NF-kappa B induced upon apoptosis. J. Cell Biol. 134:1996;12-23.
22. Gunn-Moore F.J., Tavare J.M. Apoptosis of cerebellar granule cells induced by serum withdrawal, glutamate or beta-amyloid, is independent of Jun kinase or p38 mitogen activated protein kinase activation. Neurosci. Lett. 250:1998;53-56.
23. Hirata H., Cadet J.L. Methamphetamine-induced serotonin neurotoxicity is attenuated in p53-knockout mice. Brain Res. 768:1997;345-348.
24. Hunot S., Brugg B., Ricard D., Michel P.P., Muriel M.P., Ruberg M., Faucheux B.A., Agid Y., Hirsh E.C. Nuclear translocation of NF-κB is increased in dopaminergic neurons of patients with Parkinson disease. Proc. Natl. Acad. Sci., USA. 94:1997;7531-7536.
25. Kaltshmidt C., Kaltshmidt B., Lannes-Vieira J., Kreutzberg G.W., Wekerle H., Bauerle P.A., Gehrmann J. Transcription factor NF-κB is activated in microglia during experimental autoimmune encephalomyelitis. J. Neuroimmunol. 55:1994;99-106.
26. Kaltschmidt B., Uherek M., Volk B., Baeuerle P.A., Kaltschmidt C. Transcription factor NF-κB is activated in primary neurons by amyloid peptides and in neurons surrounding early plaques from patients with Alzheimer disease. Proc. Natl. Acad. Sci., USA. 94:1997;2642-2647.
27. Kessler J.A., Ludham W.H., Freidin M.M., Hall D.H., Michaelson M.D., Spray D.C., Dougherty M., Batter D.K. Cytokine-induced programmed cell death of cultured sympathetic neurons. Neuron. 11:1993;1123-1132.
28. Kihara S., Shiraishi T., Nakagawa S., Toda K., Tabuchi K. Visualization of DNA double strand breaks in the gerbil hippocampal CA1 following transient ischemia. Neurosci. Lett. 175:1994;133-136.
29. Kobayashi T., Ruan S., Jabbur J.R., Consoli U., Clodi K., Shiku H., Owen-Schaub L.B., Andreeff M., Reed J.C., Zhang W. Differential p53 phosphorylation and activation of apoptosis-promoting genes Bax and Gas/APO-1 by irradiation and ara-C treatment. Cell Death and Diff. 5:1998;584-591.
30. Lane D.P. Cancer. p53, guardian of the genome. Nature. 358:1992;15-16.
31. LeBel C.P., Bondy S.C. Oxidative damage and cerebral aging. Prog. Neurobiol. 38:(6):1992;1-9.
32. Li Y., Chopp M., Zhang Z.G., Zaloga C., Neiwenhuis L., Gautam S. p53-immunoreactive protein and p53 mRNA expression after transient middle cerebral artery occlusion in rats. Stroke. 25:1994;849-855.
33. Lieberthal W., Triaca V., Koh J.S., Pagano P.J., Levine J.S. Role of superoxide in apoptosis induced by growth factor withdrawal. Am. J. Physiol. 275:1998;F691-F702.
34. Lin K.I., Lee S.H., Narayanan R., Baraban J.M., Mardwick J.M., Ratan R.R. Thiol agents and Bcl-2 identify an alphavirus-induced apoptotic pathway that requires activation of the transcription factor NF-kappa B. J. Cell. Biol. 131:1995;1149-1161.
35. Loo D.T., Bradford S., Helmrich A., Barnes D.W. Bcl-2 inhibits cell death of serum-free mouse embryo cells caused by epidermal growth factor deprivation. Cell. Biol. Toxicol. 14:1998;375-382.
36. MacGibbon G.A., Cooper G.J., Dragunow M. Acute application of human amylin, unlike beta-amyloid peptides, kills undifferentiated PC12 cells by apoptosis. Neuroreport. 8:1997;3945-3950.
37. McGeer P.L., McGeer E.G. Mechanisms of cell death in Alzheimer disease. J. Neural. Transm. 54:1998;159-166. (Suppl. 1).
38. Mize R.R., Holdefer R.N., Nabors L.B. Quantitative immunocytochemistry using an image analyzer. I. Hardware evaluation, image processing and data analysis. J. Neurosci. Methods. 6:1988;1-24.
39. Morrison R.S., Wenzel H.J., Kinoshita Y., Robbins C.A., Donehower L.A., Schwartzkroin P.A. Loss of the p53 tumor suppressor gene protects neurons from kainate-induced cell death. J. Neurosci. 16:1996;1337-1345.
40. Nicotera P., Ankarcrona M., Bonfoco E., Orrenius S., Lipton S.A. Neuronal necrosis and apoptosis: two distinct events induced by exposure to glutamate or oxidative stress. Adv. Neurol. 72:1997;95-101.
41. Palombo F., Hughes M., Jiricny J., Truong O., Hsuan J. Mismatch repair and cancer. Nature. 367:1994;417-418.
42. Quin Z.H., Wang Y., Nakai M., Chase T. Nuclear factor-kappa B contributes to excitotoxin-induced apoptosis in rat striatum. Mol. Pharmacol. 53:1998;33-42.
43. Rabbitt P. The aging of the brain. Nature. 297:1982;21-22.
44. Sakhi S., Bruce A., Sun N., Tocco G., Baudry M., Schreiber S.S. p53 induction is associated with neuronal damage in the central nervous system. Proc. Natl. Acad. Sci., USA. 89:1994;12028-12032.
45. Scherer S., Welter C., Zang K.D., Dooley S. Specific in vitro binding of p53 to the promoter region of the human mismatch repair hMSH2. Biochem. Biophys. Res. Commun. 221:1996;722-728.
46. Smale G., Nichols N.R., Brady D.R., Finch C.E., Horton W.E. Jr. Evidence for apoptotic cell death in Alzheimer's disease. Exp. Neurol. 133:1995;225-230.
47. Talley A.K., Dewurst S., Perry S.W., Dollard S.C., Gummuluru S., Fine S.M., New D., Epstein L.G., Gendelman B.E., Gelbard H.A. Tumor necrosis factor alpha-induced apoptosis in human neuronal cells: protection by the antioxidant N-acetylcysteine and the genes bcl-2 and crm-A. Mol. Cell Biol. 15:1995;2359-2366.
48. Tong L., Perez-Polo R. Transcription factor DNA binding activity in PC12 cells undergoing apoptosis after glucose deprivation. Neurosci. Lett. 191:1995;137-140.
49. Tong L., Perez-Polo R. Brain-derived neurotrophic factor (BDNF) protects cultured rat cerebellar granule neurons against glucose deprivation-induced apoptosis. J. Neural. Transm. 105:1998;905-914.
50. Uberti D., Belloni M., Grilli M., Spano P.F., Memo M. Induction of tumour suppressor phosphoprotein p53 in the apoptosis of cultured rat cerebellar neurons triggered by excitatory aminoacids. Eur. J. Neurosci. 10:1998;245-256.
51. Uberti, D., Yavin, E., Gil, S., Goldfinger, N. and Rotter, V., Hydrogen peroxide induces nuclear translocation of p53 and apoptosis in cells of oligodendro glia origin. Mol. Brain. Res., 1999, 65, 167-175.
52. Uker D.S. Death by suicide: one way to go in mammalian cellular development? New Biol. 3:1991;103-109.
53. Velez-Pardo C., Jimenez Del Rio M., Lopera F. Familial Alzheimer's disease: oxidative stress, beta-amyloid, presenilins, and cell death. Gen. Pharmacol. 31:1998;675-681.
54. Vogelstein B., Kinzier K.W. p53 function and dysfunction. Cell. 70:1992;523-526.
55. Ziv I., Barzilai A., Offen D., Stein R., Achiron A., Melamed E. Dopamine-induced, genotoxic activation of programmed cell death. A role in nigrostriatal neuronal degeneration in Parkinson's disease? Adv. Neurol. 69:1996;229-233.
56. 2-induced apoptosis in human neuronal cells. Biochem. Biophys. Res. Commun. 235:1997;845-848.
57. Whittemore E.R., Loo D.T., Cotman C.V. Exposure to hydrogen peroxide induces cell death via apoptosis in cultured rat cortical neurons. Neuroreport. 5:1994;1485-1488.
58. Wu H., Lozano G. NF-κB activation of p53. A potential mechanism for suppressing cell growth in response to stress. J. Biol. Chem. 269:1994;20067-20074.
59. Wyllie A.H. The genetic regulation of apoptosis. Curr. Opin. Genet. and Dev. 5:1995;97-104.
60. Yan S.D., Yan S.F., Chen X., Fu J., Chen M., Kuppusamy P., Smith M.A., Perry G., Godman G.C., Nawroth P., Zweier J.L., Stern D. Non-enzymatically glycated tau in Alzheimer's disease induces neuronal oxidant stress resulting in cytokine gene expression and release of amyloid-peptide. Nat. Med. 1:1995;693-699.
61. Yan S.D., Chen X., Fu J., Chen M., Zhu H., Roher A., Slattery T., Zhao L., Nagashima M., Morser J., Migheli A., Nawroth P., Stern D., Schmidt A.M. RAGE and amyloid-peptide neurotoxicity in Alzheimer's disease. Nature. 382:1996;685-691.
62. Yang K., Mu X.S., Hayes R.L. Increased cortical nuclear factor-kappa B (NF-kappa B) DNA binding activity after traumatic brain injury in rats. Neurosci. Letts. 19:1995;101-104.
63. Yin, M.-J., Yamamoto, Y. and Gayon, R. B., The anti-inflammatory agents aspirin and salicylate inhibit the activity of I B Kinase. Nature, 1998, 396, 77-80.
64. Xiang H., Hochman D.W., Saya H., Fujiwara T., Schwartzkroin P.A., Morrison R.S. Evidence for p53-mediated modulation of neuronal viability. J. Neurosci. 16:1996;6753-6765.
65. Xiang H., Kinoshita Y., Knudson C.M., Korsmeyer S.J., Schwartzkroin P.A., Morrison R.S. Bax involvement in p53-mediated apoptosis. J. Neurosci. 18:1998;1363-1373.