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Volumn 4, Issue 2, 2002, Pages 154-161

Rapid parallel synthesis of polymer-bound enones utilizing microwave-assisted solid-phase chemistry

Author keywords

[No Author keywords available]

Indexed keywords

KETONE; POLYMER;

EID: 0036512885     PISSN: 15204766     EISSN: None     Source Type: Journal    
DOI: 10.1021/cc010043r     Document Type: Article
Times cited : (92)

References (64)
  • 1
    • 0003572870 scopus 로고    scopus 로고
    • Principles and Practices; Marcel Dekker: New York
    • Sucholeiki, I. High-Throughput Synthesis. Principles and Practices; Marcel Dekker: New York, 2001.
    • (2001) High-throughput Synthesis
    • Sucholeiki, I.1
  • 3
    • 0000318227 scopus 로고
    • Enhanced coupling efficiency in solid-phase peptide synthesis by microwave irradiation
    • Yu, H.-M.; Chen, S.-T.; Wang, K.-T. Enhanced Coupling Efficiency in Solid-Phase Peptide Synthesis by Microwave Irradiation. J. Org. Chem. 1992, 57, 4781-4784.
    • (1992) J. Org. Chem. , vol.57 , pp. 4781-4784
    • Yu, H.-M.1    Chen, S.-T.2    Wang, K.-T.3
  • 4
    • 0007404508 scopus 로고    scopus 로고
    • Rapid microwave-assisted Suzuki coupling on solid-phase
    • Larhed, M.; Lindeberg, G.; Hallberg, A. Rapid Microwave-Assisted Suzuki Coupling on Solid-Phase. Tetrahedron Lett. 1996, 37, 8219-8222.
    • (1996) Tetrahedron Lett. , vol.37 , pp. 8219-8222
    • Larhed, M.1    Lindeberg, G.2    Hallberg, A.3
  • 5
    • 0033553530 scopus 로고    scopus 로고
    • Microwave-assisted solid-phase Ugi four-component condensations
    • Hoel, A. M. L.; Nielsen, J. Microwave-Assisted Solid-Phase Ugi Four-Component Condensations. Tetrahedron Lett. 1999, 40, 3941-3944.
    • (1999) Tetrahedron Lett. , vol.40 , pp. 3941-3944
    • Hoel, A.M.L.1    Nielsen, J.2
  • 6
    • 0032942433 scopus 로고    scopus 로고
    • Wang resin bound addition reactions under microwave irradiation
    • Yu, A.-M.; Zhang, Z.-P.; Yang, H.-Z.; Thang, C.-Y.; Liu, Z. Wang Resin Bound Addition Reactions under Microwave Irradiation. Synth. Commun. 1999, 29, 1595-1599.
    • (1999) Synth. Commun. , vol.29 , pp. 1595-1599
    • Yu, A.-M.1    Zhang, Z.-P.2    Yang, H.-Z.3    Thang, C.-Y.4    Liu, Z.5
  • 7
    • 0032848529 scopus 로고    scopus 로고
    • Solid phase-solid state synthesis of N-alkyl imides from anhydrides
    • Chandrasekhar, S.; Padmaja, M. B.; Raza, A. Solid Phase-Solid State Synthesis of N-Alkyl Imides from Anhydrides. Synlett 1999, 1597-1599.
    • (1999) Synlett , pp. 1597-1599
    • Chandrasekhar, S.1    Padmaja, M.B.2    Raza, A.3
  • 8
    • 0033605298 scopus 로고    scopus 로고
    • Solid supported aryl/heteroaryl C-N cross-coupling reactions
    • Combs, A. P.; Saubern, S.; Rafalski, M.; Lam, P. Y. S. Solid Supported Aryl/Heteroaryl C-N Cross-Coupling Reactions. Tetrahedron Lett. 1999, 40, 1623-1626.
    • (1999) Tetrahedron Lett. , vol.40 , pp. 1623-1626
    • Combs, A.P.1    Saubern, S.2    Rafalski, M.3    Lam, P.Y.S.4
  • 9
    • 0034700858 scopus 로고    scopus 로고
    • The preparation of resin bound nitroalkenes and some applications in high pressure promoted cycloadditions
    • Kuster, G.; Scheeren, H. W. The Preparation of Resin Bound Nitroalkenes and Some Applications in High Pressure Promoted Cycloadditions. Tetrahedron Lett. 2000, 41, 515-519.
    • (2000) Tetrahedron Lett. , vol.41 , pp. 515-519
    • Kuster, G.1    Scheeren, H.W.2
  • 10
    • 0034680614 scopus 로고    scopus 로고
    • Fast microwave-assisted preparation of aryl and vinyl nitriles and the corresponding tetrazoles from organo-halides
    • Alterman, M.; Hallberg, A. Fast Microwave-Assisted Preparation of Aryl and Vinyl Nitriles and the Corresponding Tetrazoles from Organo-halides. J. Org. Chem. 2000, 65, 7984-7989.
    • (2000) J. Org. Chem. , vol.65 , pp. 7984-7989
    • Alterman, M.1    Hallberg, A.2
  • 11
    • 0034222020 scopus 로고    scopus 로고
    • Spatially addressed synthesis of amino-and amino-oxy-substituted 1,3,5-triazine arrays on polymeric membranes
    • Scharn, D.; Wenschuh, H.; Reineke, U.; Schneider-Mergener, J.; Germeroth, L. Spatially Addressed Synthesis of Amino-and Amino-Oxy-Substituted 1,3,5-Triazine Arrays on Polymeric Membranes. J. Comb. Chem. 2000, 2, 361-369.
    • (2000) J. Comb. Chem. , vol.2 , pp. 361-369
    • Scharn, D.1    Wenschuh, H.2    Reineke, U.3    Schneider-Mergener, J.4    Germeroth, L.5
  • 12
    • 0035971845 scopus 로고    scopus 로고
    • The effect of microwave irradiation on carbodiimide-mediated esterifications on solid support
    • Stadler, A.; Kappe, C. O. The Effect of Microwave Irradiation on Carbodiimide-Mediated Esterifications on Solid Support. Tetrahedron 2001, 57, 3915-3920.
    • (2001) Tetrahedron , vol.57 , pp. 3915-3920
    • Stadler, A.1    Kappe, C.O.2
  • 13
    • 0006039686 scopus 로고    scopus 로고
    • Rapid parallel synthesis utilizing microwave irradiation
    • Sucholeiki, I., Ed.; Marcel Dekker: New York
    • Glass, B. M.; Combs, A. P. Rapid Parallel Synthesis Utilizing Microwave Irradiation. In High-Throughput Synthesis. Principles and Practices; Sucholeiki, I., Ed.; Marcel Dekker: New York, 2001; pp 123-128.
    • (2001) High-throughput Synthesis. Principles and Practices , pp. 123-128
    • Glass, B.M.1    Combs, A.P.2
  • 14
    • 0035118462 scopus 로고    scopus 로고
    • High speed couplings and cleavages in microwave heated, solid-phase reactions at high temperatures
    • Stadler, A.; Kappe, C. O. High Speed Couplings and Cleavages in Microwave Heated, Solid-Phase Reactions at High Temperatures. Eur. J. Org. Chem. 2001, 919-925.
    • (2001) Eur. J. Org. Chem. , pp. 919-925
    • Stadler, A.1    Kappe, C.O.2
  • 15
    • 1542710212 scopus 로고    scopus 로고
    • Solid-phase three-component domino reactions: Combinatorial approach to substituted 3,4-dihydro-2H-pyrans
    • Tietze, L. F.; Hippe, T.; Steinmetz, A. Solid-Phase Three-Component Domino Reactions: Combinatorial Approach to Substituted 3,4-Dihydro-2H-pyrans. Synlett 1996, 1043-1044.
    • (1996) Synlett , pp. 1043-1044
    • Tietze, L.F.1    Hippe, T.2    Steinmetz, A.3
  • 16
    • 0001791986 scopus 로고    scopus 로고
    • A general and expedient method for the solid-phase synthesis of structurally diverse 1-phenylpyrazolone derivatives
    • Tietze, L. F.; Steinmetz, A. A General and Expedient Method for the Solid-Phase Synthesis of Structurally Diverse 1-Phenylpyrazolone Derivatives. Synlett 1996, 667-668.
    • (1996) Synlett , pp. 667-668
    • Tietze, L.F.1    Steinmetz, A.2
  • 17
    • 0002295046 scopus 로고    scopus 로고
    • Palladium-catalyzed allylic substitution on solid support
    • Tietze, L. F.; Hippe, T.; Steinmetz, A. Palladium-Catalyzed Allylic Substitution on Solid Support. Chem. Commun. 1998, 793-794.
    • (1998) Chem. Commun. , pp. 793-794
    • Tietze, L.F.1    Hippe, T.2    Steinmetz, A.3
  • 18
    • 0032704349 scopus 로고    scopus 로고
    • Solid-phase synthesis of pyrrolo[3,4-b]pyridines and related pyridine-fused heterocycles
    • Bhandari, A.; Li, B.; Gallop, M. A. Solid-Phase Synthesis of Pyrrolo[3,4-b]pyridines and Related Pyridine-Fused Heterocycles. Synthesis 1999, 1951-1960.
    • (1999) Synthesis , pp. 1951-1960
    • Bhandari, A.1    Li, B.2    Gallop, M.A.3
  • 19
    • 0000257350 scopus 로고    scopus 로고
    • Solid-phase synthesis of highly functionalized 2,2′-bipyridines
    • Tadesse, S.; Bhandari, A.; Gallop, M. A. Solid-Phase Synthesis of Highly Functionalized 2,2′-Bipyridines. J. Comb. Chem. 1999, 1, 184-187.
    • (1999) J. Comb. Chem. , vol.1 , pp. 184-187
    • Tadesse, S.1    Bhandari, A.2    Gallop, M.A.3
  • 21
    • 0141856793 scopus 로고    scopus 로고
    • A solid phase approach to quinolones using the DIVERSOMER technology
    • MacDonald, A. A.; DeWitt, S. H.; Hogan, E. M.; Ramage, R. A Solid Phase Approach to Quinolones using the DIVERSOMER Technology. Tetrahedron Lett. 1996, 37, 4815-4818.
    • (1996) Tetrahedron Lett. , vol.37 , pp. 4815-4818
    • Macdonald, A.A.1    DeWitt, S.H.2    Hogan, E.M.3    Ramage, R.4
  • 22
    • 0030200397 scopus 로고    scopus 로고
    • Approaches to combinatorial synthesis of heterocycles: Solid phase synthesis of pyridines and pyrido[2,3-d]pyrimidines
    • Gordeev, M. F.; Patel, D. V.; Wu, J.; Gordon, E. M. Approaches to Combinatorial Synthesis of Heterocycles: Solid Phase Synthesis of Pyridines and Pyrido[2,3-d]pyrimidines. Tetrahedron Lett. 1996, 37, 4643-4646.
    • (1996) Tetrahedron Lett. , vol.37 , pp. 4643-4646
    • Gordeev, M.F.1    Patel, D.V.2    Wu, J.3    Gordon, E.M.4
  • 24
    • 0031579941 scopus 로고    scopus 로고
    • Solid-phase synthesis of polymer-bound β-ketoesters and their application in the synthesis of structurally diverse pyrazolones
    • Tietze, L. F.; Steinmetz, A.; Balkenhohl, F. Solid-Phase Synthesis of Polymer-Bound β-Ketoesters and Their Application in the Synthesis of Structurally Diverse Pyrazolones. Bioorg. Med. Chem. Lett. 1997, 7, 1303-1306.
    • (1997) Bioorg. Med. Chem. Lett. , vol.7 , pp. 1303-1306
    • Tietze, L.F.1    Steinmetz, A.2    Balkenhohl, F.3
  • 25
    • 0034621975 scopus 로고    scopus 로고
    • Solid-phase synthesis of 4-aryl-1,4-dihydropyridines via the hantzsch three component condensation
    • Breitenbucher, J. G.; Figliozzi, G. Solid-Phase Synthesis of 4-Aryl-1,4-dihydropyridines via the Hantzsch Three Component Condensation. Tetrahedron Lett. 2000, 41, 4311-4315.
    • (2000) Tetrahedron Lett. , vol.41 , pp. 4311-4315
    • Breitenbucher, J.G.1    Figliozzi, G.2
  • 26
    • 0031735308 scopus 로고    scopus 로고
    • Ketenes in soluble polymer bound synthesis: Preparation of succinamides and 4-pyridones
    • For an example involving soluble polymers, see the following. Far, A. R.; Tidwell, T. T. Ketenes in Soluble Polymer Bound Synthesis: Preparation of Succinamides and 4-Pyridones. J. Org. Chem. 1998, 63, 8636-8637.
    • (1998) J. Org. Chem. , vol.63 , pp. 8636-8637
    • Far, A.R.1    Tidwell, T.T.2
  • 27
    • 33748225668 scopus 로고    scopus 로고
    • Stereoselective solid-phase synthesis of cyclopentane and cyclohexane derivatives by two-component domino reactions: Generation of combinatorial libraries
    • Tietze, L. F.; Steinmetz, A. Stereoselective Solid-Phase Synthesis of Cyclopentane and Cyclohexane Derivatives by Two-Component Domino Reactions: Generation of Combinatorial Libraries. Angew. Chem., Int. Ed. Engl. 1996, 35, 651-652.
    • (1996) Angew. Chem., Int. Ed. Engl. , vol.35 , pp. 651-652
    • Tietze, L.F.1    Steinmetz, A.2
  • 29
    • 0033516523 scopus 로고    scopus 로고
    • Solid phase synthesis of dihydropyrimidinones and pyrimidinone carboxylic acids from malonic acid resin
    • Hamper, B. C.; Gan, K. Z.; Owen, T. J. Solid Phase Synthesis of Dihydropyrimidinones and Pyrimidinone Carboxylic Acids from Malonic Acid Resin. Tetrahedron Lett. 1999, 40, 4973-4976.
    • (1999) Tetrahedron Lett. , vol.40 , pp. 4973-4976
    • Hamper, B.C.1    Gan, K.Z.2    Owen, T.J.3
  • 30
    • 0642316448 scopus 로고    scopus 로고
    • Solid-phase synthesis of dihydropyrimidine combinatorial libraries by the atwal modification of the biginelli reaction
    • Abstracts of Papers, New Orleans, LA, American Chemical Society: Washington, DC, 1996; ORGN 122
    • Robinett, L. D.; Yager, K. M.; Phelan, J. C. Solid-Phase Synthesis of Dihydropyrimidine Combinatorial Libraries by the Atwal Modification of the Biginelli Reaction. Abstracts of Papers, 211th National Meeting of the American Chemical Society, New Orleans, LA, 1996; American Chemical Society: Washington, DC, 1996; ORGN 122.
    • (1996) 211th National Meeting of the American Chemical Society
    • Robinett, L.D.1    Yager, K.M.2    Phelan, J.C.3
  • 33
    • 0032480960 scopus 로고    scopus 로고
    • A measure of solvent effects on swelling of resins for solid phase organic synthesis
    • Santini, R.; Griffith, M. C.; Qi, M. A Measure of Solvent Effects on Swelling of Resins for Solid Phase Organic Synthesis. Tetrahedron Lett. 1998, 39, 8951-8954.
    • (1998) Tetrahedron Lett. , vol.39 , pp. 8951-8954
    • Santini, R.1    Griffith, M.C.2    Qi, M.3
  • 35
    • 0001294103 scopus 로고    scopus 로고
    • Chemoselectivity in the reaction of acetylketene and acetimidoylketene: Confirmation of theoretical predictions
    • Birney, D. M.; Xu, X.; Ham, S.; Huang, X. Chemoselectivity in the Reaction of Acetylketene and Acetimidoylketene: Confirmation of Theoretical Predictions. J. Org. Chem. 1997, 62, 7114-7120.
    • (1997) J. Org. Chem. , vol.62 , pp. 7114-7120
    • Birney, D.M.1    Xu, X.2    Ham, S.3    Huang, X.4
  • 36
    • 0025265328 scopus 로고
    • The transacetoacetylation reaction: Mechanistic implications
    • Witzeman, J. S. The Transacetoacetylation Reaction: Mechanistic Implications. Tetrahedron Lett. 1990, 31, 1401-1404.
    • (1990) Tetrahedron Lett. , vol.31 , pp. 1401-1404
    • Witzeman, J.S.1
  • 37
    • 33751499568 scopus 로고
    • Transacetoacetylation with tert-butyl acetoacetate: Synthetic applications
    • Witzeman, J. S.; Nottingham, W. D. Transacetoacetylation with tert-Butyl Acetoacetate: Synthetic Applications. J. Org. Chem. 1991, 56, 1713-1718.
    • (1991) J. Org. Chem. , vol.56 , pp. 1713-1718
    • Witzeman, J.S.1    Nottingham, W.D.2
  • 38
    • 33751499075 scopus 로고
    • Direct observation of α-oxo ketenes formed from 1,3-dioxin-4-ones and the enols of β-keto esters
    • Freiermuth, B.; Wentrup, C. Direct Observation of α-Oxo Ketenes Formed from 1,3-Dioxin-4-ones and the Enols of β-Keto Esters. J. Org. Chem. 1991, 56, 2286-2289.
    • (1991) J. Org. Chem. , vol.56 , pp. 2286-2289
    • Freiermuth, B.1    Wentrup, C.2
  • 39
    • 0033605396 scopus 로고    scopus 로고
    • Microwave-mediated derivatization of poly(styrene-co-allyl)alcohol, a key step for the polymer-assisted synthesis of heterocycles
    • For an example of a microwave-assisted acetoacetylation involving soluble polymers, see the following. Vanden Eynde, J. J.; Rutot, D. Microwave-Mediated Derivatization of Poly(styrene-co-allyl)alcohol, a Key Step for the Polymer-Assisted Synthesis of Heterocycles. Tetrahedron 1999, 55, 2687-2694.
    • (1999) Tetrahedron , vol.55 , pp. 2687-2694
    • Vanden Eynde, J.J.1    Rutot, D.2
  • 40
    • 0542421518 scopus 로고    scopus 로고
    • Monitoring the progress and the yield of solid-phase organic reactions directly on resin supports
    • Yan, B. Monitoring the Progress and the Yield of Solid-Phase Organic Reactions Directly on Resin Supports. Acc. Chem. Res. 1998, 31, 621-630.
    • (1998) Acc. Chem. Res. , vol.31 , pp. 621-630
    • Yan, B.1
  • 41
    • 0000789435 scopus 로고    scopus 로고
    • Kinetic comparison of amide formation on various cross-linked polystyrene resins
    • Li, W. B.; Xiao, X. Y.; Czarnik, A. W. Kinetic Comparison of Amide Formation on Various Cross-Linked Polystyrene Resins. J. Comb. Chem. 1999, 1, 127-129.
    • (1999) J. Comb. Chem. , vol.1 , pp. 127-129
    • Li, W.B.1    Xiao, X.Y.2    Czarnik, A.W.3
  • 42
    • 0001755220 scopus 로고    scopus 로고
    • Effects of polymer supports on the kinetics of solid-phase organic reactions: A comparison of polystyrene-and tentagel-based resins
    • Li, W.; Yan, B. Effects of Polymer Supports on the Kinetics of Solid-Phase Organic Reactions: A Comparison of Polystyrene-and TentaGel-Based Resins. J. Org. Chem. 1998, 63, 4092-4097.
    • (1998) J. Org. Chem. , vol.63 , pp. 4092-4097
    • Li, W.1    Yan, B.2
  • 43
    • 0031152153 scopus 로고    scopus 로고
    • New methods for analyzing compounds on polymeric supports
    • Gallop, M. A.; Fitch, W. L. New Methods for Analyzing Compounds on Polymeric Supports. Curr. Opin. Chem. Biol. 1997, 7, 94-100.
    • (1997) Curr. Opin. Chem. Biol. , vol.7 , pp. 94-100
    • Gallop, M.A.1    Fitch, W.L.2
  • 44
    • 0002904707 scopus 로고    scopus 로고
    • On-bead quantitation of resin bound functional groups using analogue techniques with vibrational spectroscopy
    • Pivonka, D. E. On-Bead Quantitation of Resin Bound Functional Groups Using Analogue Techniques with Vibrational Spectroscopy. J. Comb. Chem. 2000, 2, 33-38.
    • (2000) J. Comb. Chem. , vol.2 , pp. 33-38
    • Pivonka, D.E.1
  • 45
    • 0000683556 scopus 로고    scopus 로고
    • Photoacoustic FTIR spectroscopy, a nondestructive method for sensitive analysis of solid-phase organic chemistry
    • Gosselin, F.; DiRenzo, M.; Ellis, T. H.; Lubell, W. D. Photoacoustic FTIR Spectroscopy, a Nondestructive Method for Sensitive Analysis of Solid-Phase Organic Chemistry. J. Org. Chem. 1996, 61, 7980-7981.
    • (1996) J. Org. Chem. , vol.61 , pp. 7980-7981
    • Gosselin, F.1    DiRenzo, M.2    Ellis, T.H.3    Lubell, W.D.4
  • 46
    • 0002436796 scopus 로고    scopus 로고
    • Combination of single bead FTIR and chemometrics in combinatorial chemistry: Application of the multivariate calibration method in monitoring solid-phase organic synthesis
    • Yan, B.; Yan, H. B. Combination of Single Bead FTIR and Chemometrics in Combinatorial Chemistry: Application of the Multivariate Calibration Method in Monitoring Solid-Phase Organic Synthesis. J. Comb. Chem. 2001, 3, 78-84.
    • (2001) J. Comb. Chem. , vol.3 , pp. 78-84
    • Yan, B.1    Yan, H.B.2
  • 47
    • 0034452798 scopus 로고    scopus 로고
    • Infrared spectroscopy in solid-phase synthesis
    • de Miguel, Y. R.; Shearer, A. S. Infrared Spectroscopy in Solid-Phase Synthesis. Biotechnol. Bioeng. 2000, 71, 119-129.
    • (2000) Biotechnol. Bioeng. , vol.71 , pp. 119-129
    • De Miguel, Y.R.1    Shearer, A.S.2
  • 48
    • 0028789375 scopus 로고
    • Carbon-carbon bond formation on solid support: Synthesis of monoacyl piperazines by knoevenagel-type condensation reactions
    • Zaragoza, F. Carbon-Carbon Bond Formation on Solid Support: Synthesis of Monoacyl Piperazines by Knoevenagel-Type Condensation Reactions. Tetrahedron Lett. 1995, 36, 8677-8678.
    • (1995) Tetrahedron Lett. , vol.36 , pp. 8677-8678
    • Zaragoza, F.1
  • 49
    • 0000201762 scopus 로고
    • The knoevenagel condensation
    • Trost, B. M., Fleming, I., Eds.; Pergamon Press: Oxford
    • Tietze, L. F.; Beifuss, U. The Knoevenagel Condensation. Comprehensive Organic Synthesis; Trost, B. M., Fleming, I., Eds.; Pergamon Press: Oxford, 1991; Vol. 2, pp 341-390.
    • (1991) Comprehensive Organic Synthesis , vol.2 , pp. 341-390
    • Tietze, L.F.1    Beifuss, U.2
  • 50
    • 0000248247 scopus 로고
    • The knoevenagel condensation
    • Jones, G. The Knoevenagel Condensation. Org. React. 1967, 15, 204-599.
    • (1967) Org. React. , vol.15 , pp. 204-599
    • Jones, G.1
  • 51
    • 85012413822 scopus 로고
    • Wiley-Interscience: New York, London, Sydney, Toronto
    • Fieser, L. F.; Fieser, M. Reagents for Organic Synthesis; Wiley-Interscience: New York, London, Sydney, Toronto, 1977; Vol. 6, p 158.
    • (1977) Reagents for Organic Synthesis , vol.6 , pp. 158
    • Fieser, L.F.1    Fieser, M.2
  • 52
    • 0000909376 scopus 로고    scopus 로고
    • Catalytic activity of proton sponge - Application to knoevenagel condensation-reactions
    • Rodriguez, I.; Sastre, G.; Corma, A.; Iborra, S. Catalytic Activity of Proton Sponge - Application to Knoevenagel Condensation-Reactions. J. Catal. 1999, 183, 14-23.
    • (1999) J. Catal. , vol.183 , pp. 14-23
    • Rodriguez, I.1    Sastre, G.2    Corma, A.3    Iborra, S.4
  • 53
    • 0025091871 scopus 로고
    • Design of an antithrombotic antihypertensive agent (Wy-27569). Synthesis and evaluation of a series of 2-heteroaryl-substituted dihydropyridines
    • Archibald, J. L.; Bradley, G.; Opalko, A.; Ward, T. J.; White, J. C.; Ennis, C.; Shepperson, N. B. Design of an Antithrombotic Antihypertensive Agent (Wy-27569). Synthesis and Evaluation of a Series of 2-Heteroaryl-Substituted Dihydropyridines. J. Med. Chem. 1990, 33, 646-652.
    • (1990) J. Med. Chem. , vol.33 , pp. 646-652
    • Archibald, J.L.1    Bradley, G.2    Opalko, A.3    Ward, T.J.4    White, J.C.5    Ennis, C.6    Shepperson, N.B.7
  • 54
    • 0041581143 scopus 로고
    • John Wiley and Sons, Inc.: New York, Chichester, Brisbane, Toronto
    • Fieser, L. F.; Fieser, M. Reagents for Organic Synthesis; John Wiley and Sons, Inc.: New York, Chichester, Brisbane, Toronto, 1967; Vol. 1, pp 1024-1027.
    • (1967) Reagents for Organic Synthesis , vol.1 , pp. 1024-1027
    • Fieser, L.F.1    Fieser, M.2
  • 55
    • 0030756775 scopus 로고    scopus 로고
    • Solid phase synthesis of 2-aminobutadienes using a piperazine linker
    • For another solid-phase synthesis of enones 3, see the following. Hird, N. W.; Irie, K.; Nagai, K. Solid Phase Synthesis of 2-Aminobutadienes Using a Piperazine Linker. Tetrahedron Lett. 1997, 38, 7111-7114.
    • (1997) Tetrahedron Lett. , vol.38 , pp. 7111-7114
    • Hird, N.W.1    Irie, K.2    Nagai, K.3
  • 56
    • 0035813242 scopus 로고    scopus 로고
    • A tentative rationalization of microwave effects in organic synthesis according to the reaction medium, and mechanistic considerations
    • For a recent review, see the following. Perreux, L.; Loupy, A. A Tentative Rationalization of Microwave Effects in Organic Synthesis According to the Reaction Medium, and Mechanistic Considerations. Tetrahedron 2001, 57, 9199-9223.
    • (2001) Tetrahedron , vol.57 , pp. 9199-9223
    • Perreux, L.1    Loupy, A.2
  • 57
    • 0035341584 scopus 로고    scopus 로고
    • Microwave-assisted high-speed chemistry: A new technique in drug discovery
    • For recent reviews on this theme, see the following. (a) Larhed, M.; Hallberg, A. Microwave-Assisted High-Speed Chemistry: A New Technique in Drug Discovery. Drug Discovery Today 2001, 6, 406-416.
    • (2001) Drug Discovery Today , vol.6 , pp. 406-416
    • Larhed, M.1    Hallberg, A.2
  • 58
    • 0036603599 scopus 로고    scopus 로고
    • High-speed combinatorial synthesis utilizing microwave irradiation
    • in press
    • (b) Kappe, C. O. High-Speed Combinatorial Synthesis Utilizing Microwave Irradiation. Curr. Opin. Chem. Biol., in press.
    • Curr. Opin. Chem. Biol.
    • Kappe, C.O.1
  • 59
    • 0041461964 scopus 로고    scopus 로고
    • Increasing rates of reaction: Microwave-assisted organic synthesis for combinatorial chemistry
    • (c) Lew, A.; Krutzik, P. O.; Hart, M. E.; Chamberlin, A. R. Increasing Rates of Reaction: Microwave-Assisted Organic Synthesis for Combinatorial Chemistry. J. Comb. Chem. 2002, 4, XXXX-XXXX.
    • (2002) J. Comb. Chem. , vol.4
    • Lew, A.1    Krutzik, P.O.2    Hart, M.E.3    Chamberlin, A.R.4
  • 61
    • 0009995308 scopus 로고    scopus 로고
    • Parallelsynthesen im mikrowellenfeld (parallel syntheses in microwave fields)
    • January
    • For a brief description, see the following. Nüchter, M.; Lautenschläger, W.; Ondruschka, B.; Tied, A. Parallelsynthesen im Mikrowellenfeld (Parallel Syntheses in Microwave Fields). LaborPraxis 2001, 25 (January), 28-31.
    • (2001) Laborpraxis , vol.25 , pp. 28-31
    • Nüchter, M.1    Lautenschläger, W.2    Ondruschka, B.3    Tied, A.4
  • 62
    • 0001260317 scopus 로고    scopus 로고
    • Automated library generation using sequential microwave-assisted chemistry. Application toward the biginelli multicomponent condensation
    • Stadler, A.; Kappe, C. O. Automated Library Generation Using Sequential Microwave-Assisted Chemistry. Application toward the Biginelli Multicomponent Condensation. J. Comb. Chem. 2001, 3, 624-630.
    • (2001) J. Comb. Chem. , vol.3 , pp. 624-630
    • Stadler, A.1    Kappe, C.O.2
  • 63
    • 0035353145 scopus 로고    scopus 로고
    • Speeding up solid-phase chemistry by microwave irradiation: A tool for high-throughput synthesis
    • Kappe, C. O. Speeding Up Solid-Phase Chemistry by Microwave Irradiation: A Tool for High-Throughput Synthesis. Am. Lab. 2001, 33 (10), 13-19.
    • (2001) Am. Lab. , vol.33 , Issue.10 , pp. 13-19
    • Kappe, C.O.1
  • 64
    • 0041581145 scopus 로고    scopus 로고
    • Milestone, Inc., 160B Shelton Road, Monroe, CT 06468. Phone: +1-203/261-6175. Fax: 1 1-203/261-6592. Web site: http://www.milestonesci.com/. E-mail: mwave@ milestonesci.com
    • Milestone, Inc., 160B Shelton Road, Monroe, CT 06468. Phone: +1-203/261-6175. Fax: 1 1-203/261-6592. Web site: http://www.milestonesci.com/. E-mail: mwave@ milestonesci.com.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.