메뉴 건너뛰기




Volumn 8, Issue 6, 1999, Pages 1332-1341

A novel recombinant single-chain hepatitis C virus NS3-NS4A protein with improved helicase activity

Author keywords

Helicase; Hepatitis C; NS3; NS4A; Recombinant

Indexed keywords

HELICASE; RECOMBINANT PROTEIN;

EID: 0033059980     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.8.6.1332     Document Type: Article
Times cited : (52)

References (53)
  • 1
    • 0029948642 scopus 로고    scopus 로고
    • Cytolysis of tumor cells expressing the Neu/erbB-2, erbB-3, and erbB-4 receptors by genetically targeted naive T lymphocytes
    • Altenschmidt U, Kahl R, Moritz D, Schnierle BS, Gerstmayer B, Wels W, Groner B. 1996. Cytolysis of tumor cells expressing the Neu/erbB-2, erbB-3, and erbB-4 receptors by genetically targeted naive T lymphocytes. Clin Cancer Res 2:1001-1008.
    • (1996) Clin Cancer Res , vol.2 , pp. 1001-1008
    • Altenschmidt, U.1    Kahl, R.2    Moritz, D.3    Schnierle, B.S.4    Gerstmayer, B.5    Wels, W.6    Groner, B.7
  • 2
    • 0024377134 scopus 로고
    • Detection of antibody to hepatitis C virus in prospectively followed transfusion recipients with acute and chronic non-A, non-B hepatitis
    • Alter HJ, Purcell RH, Shih JW, Melpolder JC, Houghton M, Choo QL, Kuo G. 1989. Detection of antibody to hepatitis C virus in prospectively followed transfusion recipients with acute and chronic non-A, non-B hepatitis. N Engl J Med 321:1494-1500.
    • (1989) N Engl J Med , vol.321 , pp. 1494-1500
    • Alter, H.J.1    Purcell, R.H.2    Shih, J.W.3    Melpolder, J.C.4    Houghton, M.5    Choo, Q.L.6    Kuo, G.7
  • 3
    • 0028016286 scopus 로고
    • The epidemiology of viral hepatitis in the United States
    • Alter MJ, Mast EE. 1994. The epidemiology of viral hepatitis in the United States. Gastroenterol Clin North Am 23:437-455.
    • (1994) Gastroenterol Clin North Am , vol.23 , pp. 437-455
    • Alter, M.J.1    Mast, E.E.2
  • 5
    • 0024509701 scopus 로고
    • Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome
    • Choo QL, Kuo G, Weiner AJ, Overby LR, Bradley DW, Houghton M. 1989. Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome. Science 244:359-362.
    • (1989) Science , vol.244 , pp. 359-362
    • Choo, Q.L.1    Kuo, G.2    Weiner, A.J.3    Overby, L.R.4    Bradley, D.W.5    Houghton, M.6
  • 6
    • 0028851296 scopus 로고
    • An amino-terminal domain of the hepatitis C virus NS3 protease is essential for interaction with NS4A
    • Failla C, Tomei L, De Francesco R. 1995. An amino-terminal domain of the hepatitis C virus NS3 protease is essential for interaction with NS4A. J Virol 69:1769-1777.
    • (1995) J Virol , vol.69 , pp. 1769-1777
    • Failla, C.1    Tomei, L.2    De Francesco, R.3
  • 7
    • 1842294626 scopus 로고    scopus 로고
    • The motif V of plum pox potyvirus CI RNA helicase is involved in NTP hydrolysis and is essential for virus RNA replication
    • Fernandez A, Guo HS, Saenz P, Simon-Buela L, Gomez de Cedron M, Garcia JA. 1997. The motif V of plum pox potyvirus CI RNA helicase is involved in NTP hydrolysis and is essential for virus RNA replication. Nucleic Acids Res 25:4474-4480.
    • (1997) Nucleic Acids Res , vol.25 , pp. 4474-4480
    • Fernandez, A.1    Guo, H.S.2    Saenz, P.3    Simon-Buela, L.4    Gomez De Cedron, M.5    Garcia, J.A.6
  • 8
    • 0032531091 scopus 로고    scopus 로고
    • Chimeric receptors providing both primary and costimulatory signaling in T cells from a single gene product
    • Finney HM, Lawson AD, Bebbington CR, Weir AN. 1998. Chimeric receptors providing both primary and costimulatory signaling in T cells from a single gene product. J Immunol 161:2791-2797.
    • (1998) J Immunol , vol.161 , pp. 2791-2797
    • Finney, H.M.1    Lawson, A.D.2    Bebbington, C.R.3    Weir, A.N.4
  • 10
    • 0023705613 scopus 로고
    • A novel super-family of nucleoside triphosphate-binding motif containing proteins which are probably involved in duplex unwinding in DNA and RNA replication and recombination
    • Gorbalenya AE, Koonin EV, Donchenko AP, Blinov VM. 1988. A novel super-family of nucleoside triphosphate-binding motif containing proteins which are probably involved in duplex unwinding in DNA and RNA replication and recombination. FEBS Lett 235:16-24.
    • (1988) FEBS Lett , vol.235 , pp. 16-24
    • Gorbalenya, A.E.1    Koonin, E.V.2    Donchenko, A.P.3    Blinov, V.M.4
  • 11
    • 0027476809 scopus 로고
    • Expression and identification of hepatitis C virus polyprotein cleavage products
    • Grakoui A, Wychowski C, Lin C, Feinstone SM, Rice CM. 1993. Expression and identification of hepatitis C virus polyprotein cleavage products. J Virol 67:1385-1395.
    • (1993) J Virol , vol.67 , pp. 1385-1395
    • Grakoui, A.1    Wychowski, C.2    Lin, C.3    Feinstone, S.M.4    Rice, C.M.5
  • 12
    • 0029861759 scopus 로고    scopus 로고
    • Vaccinia virions lacking the RNA helicase nucleoside triphosphate phosphohydrolase II are defective in early transcription
    • Gross CH, Shuman S. 1996. Vaccinia virions lacking the RNA helicase nucleoside triphosphate phosphohydrolase II are defective in early transcription. J Virol 70:8549-8557.
    • (1996) J Virol , vol.70 , pp. 8549-8557
    • Gross, C.H.1    Shuman, S.2
  • 13
    • 0031901334 scopus 로고    scopus 로고
    • The nucleoside triphosphatase and helicase activities of vaccinia virus NPH-II are essential for virus replication
    • Gross CH, Shuman S. 1998. The nucleoside triphosphatase and helicase activities of vaccinia virus NPH-II are essential for virus replication. J Virol 72:4729-4736.
    • (1998) J Virol , vol.72 , pp. 4729-4736
    • Gross, C.H.1    Shuman, S.2
  • 14
    • 0001601499 scopus 로고
    • NTPase activity of hepatitis C virus NS3 protein expressed in insect cells
    • Gwack Y, Kim DW, Han JH, Choe J. 1995. NTPase activity of hepatitis C virus NS3 protein expressed in insect cells. Mol Cells 5:171-175.
    • (1995) Mol Cells , vol.5 , pp. 171-175
    • Gwack, Y.1    Kim, D.W.2    Han, J.H.3    Choe, J.4
  • 15
    • 0030583249 scopus 로고    scopus 로고
    • Characterization of RNA binding activity and RNA helicase activity of the hepatitis C virus NS3 protein
    • Gwack Y, Kim DW, Han JH, Choe J. 1996. Characterization of RNA binding activity and RNA helicase activity of the hepatitis C virus NS3 protein. Biochem Biophys Res Commun 225:654-659.
    • (1996) Biochem Biophys Res Commun , vol.225 , pp. 654-659
    • Gwack, Y.1    Kim, D.W.2    Han, J.H.3    Choe, J.4
  • 16
    • 0030735535 scopus 로고    scopus 로고
    • DNA helicase activity of the hepatitis C virus nonstructural protein 3
    • Gwack Y, Kim DW, Han JH, Choe J. 1997. DNA helicase activity of the hepatitis C virus nonstructural protein 3. Eur J Biochem 250:47-54.
    • (1997) Eur J Biochem , vol.250 , pp. 47-54
    • Gwack, Y.1    Kim, D.W.2    Han, J.H.3    Choe, J.4
  • 17
    • 0027026780 scopus 로고
    • Comparative molecular biology of flaviviruses and hepatitis C virus
    • Heinz FX. 1992. Comparative molecular biology of flaviviruses and hepatitis C virus. Arch Virol Suppl 4:163-171.
    • (1992) Arch Virol Suppl , vol.4 , pp. 163-171
    • Heinz, F.X.1
  • 18
    • 0028884176 scopus 로고
    • Expression, isolation, and characterization of the hepatitis C virus ATPase/RNA helicase
    • Jin L, Peterson DL. 1995. Expression, isolation, and characterization of the hepatitis C virus ATPase/RNA helicase. Arch Biochem Biophys 323:47-53.
    • (1995) Arch Biochem Biophys , vol.323 , pp. 47-53
    • Jin, L.1    Peterson, D.L.2
  • 19
    • 0028817781 scopus 로고
    • C-terminal domain of the hepatitis C virus NS3 protein contains an RNA helicase activity
    • Kim DW, Gwack Y, Han JH, Choe J. 1995. C-terminal domain of the hepatitis C virus NS3 protein contains an RNA helicase activity. Biochem Biophys Res Commun 215:160-166.
    • (1995) Biochem Biophys Res Commun , vol.215 , pp. 160-166
    • Kim, D.W.1    Gwack, Y.2    Han, J.H.3    Choe, J.4
  • 20
    • 0342872087 scopus 로고    scopus 로고
    • Towards defining a minimal functional domain for NTPase and RNA helicase activities of the hepatitis C virus NS3 protein
    • Kim DW, Gwack Y, Han JH, Choe J. 1997a. Towards defining a minimal functional domain for NTPase and RNA helicase activities of the hepatitis C virus NS3 protein. Virus Res 49:17-25.
    • (1997) Virus Res , vol.49 , pp. 17-25
    • Kim, D.W.1    Gwack, Y.2    Han, J.H.3    Choe, J.4
  • 21
    • 0013627747 scopus 로고    scopus 로고
    • Mutational analysis of the hepatitis C virus RNA helicase
    • Kim DW, Kim J, Gwack Y, Han JH, Choe J. 1997b. Mutational analysis of the hepatitis C virus RNA helicase. J Virol 71:9400-9409.
    • (1997) J Virol , vol.71 , pp. 9400-9409
    • Kim, D.W.1    Kim, J.2    Gwack, Y.3    Han, J.H.4    Choe, J.5
  • 23
    • 0030198933 scopus 로고    scopus 로고
    • In vitro studies on the activation of the hepatitis C virus NS3 proteinase by the NS4A cofactor
    • Koch JO, Lohmann V, Herian U, Bartenschlager R. 1996. In vitro studies on the activation of the hepatitis C virus NS3 proteinase by the NS4A cofactor. Virology 221:54-66.
    • (1996) Virology , vol.221 , pp. 54-66
    • Koch, J.O.1    Lohmann, V.2    Herian, U.3    Bartenschlager, R.4
  • 24
    • 0027504136 scopus 로고
    • Evolution and taxonomy of positive-strand RNA viruses: Implications of comparative analysis of amino acid sequences
    • Published erratum appears in Crit Rev Biochem Mol Biol. 1993. 28(6):546
    • Koonin EV, Dolja VV. 1993. Evolution and taxonomy of positive-strand RNA viruses: Implications of comparative analysis of amino acid sequences. Crit Rev Biochem Mol Biol 28:375-430. [Published erratum appears in Crit Rev Biochem Mol Biol. 1993. 28(6):546.]
    • (1993) Crit Rev Biochem Mol Biol , vol.28 , pp. 375-430
    • Koonin, E.V.1    Dolja, V.V.2
  • 25
    • 0031911760 scopus 로고    scopus 로고
    • Comparisons between the structures of HCV and Rep helicases reveal structural similarities between SF1 and SF2 super-families of helicases
    • Korolev S, Yao N, Lohman TM, Weber PC, Waksman G. 1998. Comparisons between the structures of HCV and Rep helicases reveal structural similarities between SF1 and SF2 super-families of helicases. Protein Sci 7:605-610.
    • (1998) Protein Sci , vol.7 , pp. 605-610
    • Korolev, S.1    Yao, N.2    Lohman, T.M.3    Weber, P.C.4    Waksman, G.5
  • 27
    • 0027979233 scopus 로고
    • Properties of purified recombinant poliovirus protein 3aB as substrate for viral proteinases and as cofactor for RNA polymerase 3Dpol
    • Lama J, Paul AV, Harris KS, Wimmer E. 1994. Properties of purified recombinant poliovirus protein 3aB as substrate for viral proteinases and as cofactor for RNA polymerase 3Dpol. J Biol Chem 269:66-70.
    • (1994) J Biol Chem , vol.269 , pp. 66-70
    • Lama, J.1    Paul, A.V.2    Harris, K.S.3    Wimmer, E.4
  • 28
    • 0030871616 scopus 로고    scopus 로고
    • Mechanistic role of an NS4A peptide cofactor with the truncated NS3 protease of hepatitis C virus: Elucidation of the NS4A stimulatory effect via kinetic analysis and inhibitor mapping
    • Landro JA, Raybuck SA, Luong YPC, O'Malley ET, Harbeson SL, Morgenstern KA, Rao G, Livingston DJ. 1997. Mechanistic role of an NS4A peptide cofactor with the truncated NS3 protease of hepatitis C virus: Elucidation of the NS4A stimulatory effect via kinetic analysis and inhibitor mapping. Biochemistry 36:9340-9348.
    • (1997) Biochemistry , vol.36 , pp. 9340-9348
    • Landro, J.A.1    Raybuck, S.A.2    Luong, Y.P.C.3    O'Malley, E.T.4    Harbeson, S.L.5    Morgenstern, K.A.6    Rao, G.7    Livingston, D.J.8
  • 29
    • 0029094449 scopus 로고
    • The hepatitis C virus NS3 serine proteinase and NS4A cofactor: Establishment of a cell-free trans-processing assay
    • Lin C, Rice CM. 1995. The hepatitis C virus NS3 serine proteinase and NS4A cofactor: Establishment of a cell-free trans-processing assay. Proc Natl Acad Sci USA 92:7622-7626.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 7622-7626
    • Lin, C.1    Rice, C.M.2
  • 30
    • 0029813908 scopus 로고    scopus 로고
    • Processing pathways of the hepatitis C virus proteins
    • Lohmann V, Koch JO, Bartenschlager R. 1996. Processing pathways of the hepatitis C virus proteins. J Hepatol 24:11-19.
    • (1996) J Hepatol , vol.24 , pp. 11-19
    • Lohmann, V.1    Koch, J.O.2    Bartenschlager, R.3
  • 31
    • 0027265676 scopus 로고
    • Molecular classification of hepatitis C virus
    • Mizokami M, Ohba K. 1993. Molecular classification of hepatitis C virus. Gastroenterol Jpn 28(Suppl 5):42-44.
    • (1993) Gastroenterol Jpn , vol.28 , Issue.SUPPL. 5 , pp. 42-44
    • Mizokami, M.1    Ohba, K.2
  • 32
    • 0031000887 scopus 로고    scopus 로고
    • Polynucleotide modulation of the protease, nucleoside triphosphatase, and helicase activities of a hepatitis C virus NS3-NS4A complex isolated from transfected COS cells
    • Morgenstern KA, Landro JA, Hsiao K, Lin C, Gu Y, Su MS, Thomson JA. 1997. Polynucleotide modulation of the protease, nucleoside triphosphatase, and helicase activities of a hepatitis C virus NS3-NS4A complex isolated from transfected COS cells. J Virol 71:3767-3775.
    • (1997) J Virol , vol.71 , pp. 3767-3775
    • Morgenstern, K.A.1    Landro, J.A.2    Hsiao, K.3    Lin, C.4    Gu, Y.5    Su, M.S.6    Thomson, J.A.7
  • 33
    • 0031726451 scopus 로고    scopus 로고
    • Production and characterization of a bivalent single chain Fv/alkaline phosphatase conjugate specific for the hemocyanin of the scorpion Androctonus australis
    • Mousli M, Goyffon M, Billiald P. 1998. Production and characterization of a bivalent single chain Fv/alkaline phosphatase conjugate specific for the hemocyanin of the scorpion Androctonus australis [In Process Citation]. Biochim Biophys Acta 1425:348-360.
    • (1998) Biochim Biophys Acta , vol.1425 , pp. 348-360
    • Mousli, M.1    Goyffon, M.2    Billiald, P.3
  • 34
    • 0030997669 scopus 로고    scopus 로고
    • Nuclear localization of the NS3 protein of hepatitis C virus and factors affecting the localization
    • Muramatsu S, Ishido S, Fujita T, Itoh M, Hotta H. 1997. Nuclear localization of the NS3 protein of hepatitis C virus and factors affecting the localization. J Virol 77:4954-4961.
    • (1997) J Virol , vol.77 , pp. 4954-4961
    • Muramatsu, S.1    Ishido, S.2    Fujita, T.3    Itoh, M.4    Hotta, H.5
  • 35
    • 0030024527 scopus 로고    scopus 로고
    • Evolutionary relationship of hepatitis C, pesti-, flavi-, plantviruses, and newly discovered GB hepatitis agents
    • Ohba K, Mizokami M, Lau JY, Orito E, Ikeo K, Gojobori T. 1996. Evolutionary relationship of hepatitis C, pesti-, flavi-, plantviruses, and newly discovered GB hepatitis agents. FEBS Lett 378:232-234.
    • (1996) FEBS Lett , vol.378 , pp. 232-234
    • Ohba, K.1    Mizokami, M.2    Lau, J.Y.3    Orito, E.4    Ikeo, K.5    Gojobori, T.6
  • 36
    • 0032501714 scopus 로고    scopus 로고
    • Randomised, double-blind, placebo-controlled trial of interferon alpha-2b with and without ribavirin for chronic hepatitis C. The Swedish Study Group
    • Reichard O, Norkrans G, Fryden A, Braconier JH, Sonnerborg A, Weiland O. 1998. Randomised, double-blind, placebo-controlled trial of interferon alpha-2b with and without ribavirin for chronic hepatitis C. The Swedish Study Group [see comments]. Lancet 351:83-87.
    • (1998) Lancet , vol.351 , pp. 83-87
    • Reichard, O.1    Norkrans, G.2    Fryden, A.3    Braconier, J.H.4    Sonnerborg, A.5    Weiland, O.6
  • 39
    • 0029655995 scopus 로고    scopus 로고
    • Identification of the sequence on NS4A required for enhanced cleavage of the NS5A/5B site by hepatitis C virus NS3 protease
    • Shimizu Y, Yamaji K, Masuho Y, Yokota T, Inoue H, Sudo K, Satoh S, Shimotohno K. 1996. Identification of the sequence on NS4A required for enhanced cleavage of the NS5A/5B site by hepatitis C virus NS3 protease. J Virol 70:127-132.
    • (1996) J Virol , vol.70 , pp. 127-132
    • Shimizu, Y.1    Yamaji, K.2    Masuho, Y.3    Yokota, T.4    Inoue, H.5    Sudo, K.6    Satoh, S.7    Shimotohno, K.8
  • 41
    • 0029959532 scopus 로고    scopus 로고
    • Virology of hepatitis C virus
    • Simmonds P. 1996. Virology of hepatitis C virus. Clin Ther 18(Suppl B):9-36.
    • (1996) Clin Ther , vol.18 , Issue.SUPPL. B , pp. 9-36
    • Simmonds, P.1
  • 42
    • 0027199917 scopus 로고
    • Hepatitis C virus NS3 protein polynucleotide-stimulated nucleoside triphosphatase and comparison with the related pestivirus and flavivirus enzymes
    • Suzich JA, Tamura JK, Palmer-Hill F, Warrener P, Grakoui A, Rice CM, Feinstone SM, Collett MS. 1993. Hepatitis C virus NS3 protein polynucleotide-stimulated nucleoside triphosphatase and comparison with the related pestivirus and flavivirus enzymes. J Virol 67:6152-6158.
    • (1993) J Virol , vol.67 , pp. 6152-6158
    • Suzich, J.A.1    Tamura, J.K.2    Palmer-Hill, F.3    Warrener, P.4    Grakoui, A.5    Rice, C.M.6    Feinstone, S.M.7    Collett, M.S.8
  • 43
    • 0029970903 scopus 로고    scopus 로고
    • The helicase activity associated with hepatitis C virus nonstructural protein 3 (NS3)
    • Tai CL, Chi WK, Chen DS, Hwang LH. 1996. The helicase activity associated with hepatitis C virus nonstructural protein 3 (NS3). J Virol 70:8477-8484.
    • (1996) J Virol , vol.70 , pp. 8477-8484
    • Tai, C.L.1    Chi, W.K.2    Chen, D.S.3    Hwang, L.H.4
  • 45
    • 0028089750 scopus 로고
    • Hepatitis C virus polyprotein processing: Kinetics and mutagenic analysis of serine proteinase-dependent cleavage
    • Tanji Y, Hijikata M, Hirowatari Y, Shimotohno K. 1994. Hepatitis C virus polyprotein processing: Kinetics and mutagenic analysis of serine proteinase-dependent cleavage. J Virol 68:8418-8422.
    • (1994) J Virol , vol.68 , pp. 8418-8422
    • Tanji, Y.1    Hijikata, M.2    Hirowatari, Y.3    Shimotohno, K.4
  • 46
    • 0028831056 scopus 로고
    • Hepatitis C virus-encoded nonstructural protein NS4A has versatile functions in viral protein processing
    • Tanji Y, Hijikata M, Satoh S, Kaneko T, Shimotohno K. 1995. Hepatitis C virus-encoded nonstructural protein NS4A has versatile functions in viral protein processing. J Virol 69:1575-1581.
    • (1995) J Virol , vol.69 , pp. 1575-1581
    • Tanji, Y.1    Hijikata, M.2    Satoh, S.3    Kaneko, T.4    Shimotohno, K.5
  • 47
    • 0031789165 scopus 로고    scopus 로고
    • Construction, expression and characterization of a novel fully activated recombinant single-chain hepatitis C virus protease
    • Taremi SS, Beyer B, Maher M, Yao N, Prosise W, Weber PC, Malcolm BA. 1998. Construction, expression and characterization of a novel fully activated recombinant single-chain hepatitis C virus protease. Protein Sci 7:1-7
    • (1998) Protein Sci , vol.7 , pp. 1-7
    • Taremi, S.S.1    Beyer, B.2    Maher, M.3    Yao, N.4    Prosise, W.5    Weber, P.C.6    Malcolm, B.A.7
  • 48
    • 0029940111 scopus 로고    scopus 로고
    • A central hydrophobic domain of the hepatitis C virus NS4A protein is necessary and sufficient for the activation of the NS3 protease
    • Tomei L, Failla C, Vitale RL, Bianchi E, De Francesco R. 1996. A central hydrophobic domain of the hepatitis C virus NS4A protein is necessary and sufficient for the activation of the NS3 protease. J Gen Virol 77:1065-1070.
    • (1996) J Gen Virol , vol.77 , pp. 1065-1070
    • Tomei, L.1    Failla, C.2    Vitale, R.L.3    Bianchi, E.4    De Francesco, R.5
  • 49
    • 0000154691 scopus 로고    scopus 로고
    • WHO concerns on hepatitis C
    • WHO Press Release. 1998. WHO concerns on hepatitis C. Lancet 351:1415.
    • (1998) Lancet , vol.351 , pp. 1415
  • 51
    • 0029044382 scopus 로고
    • Interaction between the 5'-terminal cloverleaf and 3AB/3CDpro of poliovirus is essential for RNA replication
    • Xiang W, Harris KS, Alexander L, Wimmer E. 1995. Interaction between the 5'-terminal cloverleaf and 3AB/3CDpro of poliovirus is essential for RNA replication. J Virol 69:3658-3667.
    • (1995) J Virol , vol.69 , pp. 3658-3667
    • Xiang, W.1    Harris, K.S.2    Alexander, L.3    Wimmer, E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.