Baculoviruses and apoptosis: The good, the bad, and the ugly

Cell Death and Differentiation

Volumn 8, Issue 2, 2001, Pages 137-143

  Clem, R J ^a  

^a KANSAS STATE UNIVERSITY   (United States)

Author keywords

Apoptosis; Baculovirus; Caspase; Iap; Insect immunity; P35

Indexed keywords

CASPASE INHIBITOR; INHIBITOR OF APOPTOSIS PROTEIN; PROTEIN P35; VIRUS PROTEIN;

ANIMAL CELL; APOPTOSIS; BACULOVIRUS; CONTROLLED STUDY; CYTOKINESIS; GENETIC ANALYSIS; GENETIC CODE; GENETIC CONSERVATION; HOST CELL; HOST RESISTANCE; HUMAN; HUMAN CELL; INSECT; MULTIGENE FAMILY; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; REVIEW; STRAIN DIFFERENCE; VIRAL GENETICS; VIRUS CELL INTERACTION; VIRUS GENE; VIRUS PATHOGENESIS; VIRUS REPLICATION; VIRUS STRAIN; YEAST;

ANIMALS; APOPTOSIS; BACULOVIRIDAE; CASPASES; CYTOKINES; HOST-PARASITE RELATIONS; INHIBITOR OF APOPTOSIS PROTEINS; INSECTS; MUTATION; VIRAL PROTEINS; VIRUS DISEASES; VIRUS REPLICATION;

ANIMALIA; INSECTA; UNIDENTIFIED BACULOVIRUS;

EID: 0035092810     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4400821     Document Type: Review

References (50)

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3. Control of programmed cell death by the baculovirus genes p35 and iap
4. The roles of eighteen baculovirus late expression factor genes in transcription and DNA replication
5. Induction of apoptosis by baculovirus transactivator IE1
6. The baculovirus PE38 protein augments apoptosis induced by transactivator IE1
7. Functional domains of the p10 protein of Autographa californica nuclear polyhedrosis virus
8. The adenovirus death protein (E3-11.6K) is required at very late stages of infection for efficient cell lysis and release of adenovirus from infected cells
9. Divergent transcription of early 35 and 94-kilodalton protein genes encoded by the Hind-III K genome fragment of the baculovirus Autographa californica nuclear polyhedrosis virus
10. Inhibition of ICE family proteases by baculovirus antiapoptotic protein p35
11. Inhibition of the Caenorhabditis elegans cell-death protease CED-3 by a CED-3 cleavage site in baculovirus p35 protein
12. Apoptotic suppression by baculovirus P35 involves cleavage by and inhibition of a virus-induced CED-3/ICE-like protease
13. Crystal structure of baculovirus P35: Role of a novel reactive site loop in apoptotic caspase inhibition
14. Caspase inhibition by baculovirus P35 requires interaction between the reactive site loop and the beta-sheet core
15. Identification and characterization of the p35 gene of Bombyx mori nuclear polyhedrosis virus that prevents virus-induced apoptosis
16. Isolation of an apoptosis suppressor gene of the Spodoptera littoralis nucleopolyhedrovirus
17. The Drosophila caspase DRONC cleaves following glutamate or aspartate and is regulated by DIAP1, HID, and GRIM
18. The Drosophila caspase DRONC is regulated by DIAP1
19. Caspase inhibitor P35 and inhibitor of apoptosis Op-IAP block in vivo proteolytic activation of an effector caspase at different steps
20. An apopstosis-inhibiting baculovirus gene with a zinc finger-like motif
21. Anti-apoptotic genes of baculoviruses
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24. An exegesis of IAPs: Salvation and surprises from BIR motifs
25. A mutational analysis of the baculovirus inhibitor of apoptosis Op-IAP
26. A single BIR domain of XIAP sufficient for inhibiting caspases
27. IAP family proteins-suppressors of apoptosis
28. Induction of apoptosis by Drosophila reaper, hid and grim through inhibition of IAP function
29. The Drosophila caspase inhibitor DIAP1 is essential for cell survival and is negatively regulated by HID
30. Baculovirus inhibitor of apoptosis functions at or upstream of the apoptotic suppressor P35 to prevent programmed cell death
31. Baculovirus inhibitors of apoptosis (IAPs) block activation of Sf-caspase-1
32. Evolutionary conservation of apoptosis mechanisms: Lepidopteran and baculoviral inhibitor of apoptosis proteins are inhibitors of mammalian caspase-9
33. The BIR motifs mediate dominant interference and oligomerization of inhibitor of apoptosis Op-IAP
34. Anti- and pro-apoptotic activities of baculovirus and Drosophila IAPs in an insect cell line
35. Baculovirus-based genetic screen for antiapoptotic genes identifies a novel IAP
36. Conservation of baculovirus inhibitor of apoptosis repeat proteins (BIRPs) in viruses, nematodes, vertebrates and yeasts
37. Caenorhabditis elegans inhibitor of apoptosis protein (IAP) homologue BIR-1 plays a conserved role in cytokinesis
38. Cell division regulation by BIR1, a member of the inhibitor of apoptosis family in yeast
39. Role for yeast inhibitor of apoptosis (IAP)-like proteins in cell division
40. Participation of Bir1p, a member of the inhibitor of apoptosis family, in yeast chromosome segregation events
41. Control of apoptosis and mitotic spindle checkpoint by survivin
42. A novel cysteine-rich sequence motif
43. RING domains: Master builders of molecular scaffolds?
44. One RING to rule a superfamily of E3 ubiquitin ligases
45. Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli
46. The inhibitor of apoptosis, cIAP2, functions as a ubiquitin-protein ligase and promotes in vitro monoubiquitination of caspases 3 and 7
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48. Apoptosis reduces both the in vitro replication and the in vivo infectivity of a baculovirus
49. Site-specific mutagenesis of the 35-kilodalton protein gene encoded by Autographa californica nuclear polyhedrosis virus: Cell line-specific effects on virus replication
50. Influence of infection route on the infectivity of baculovirus mutants lacking the apoptosis-inhibiting gene p35 and the adjacent gene p94