Characterization of a neuronal κB-binding factor distinct from NF-κB

Molecular Brain Research

Volumn 67, Issue 2, 1999, Pages 303-315

  Moerman, Andrèa M ^a   Mao, Xianrong ^a   Lucas, Mandy M ^a   Barger, Steven W ^a,b  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b Geriatric Res Educ Clinical Center   (United States)

Author keywords

Electrophoretic mobility shift assay; NF B; Rel; Transcription factor; UV crosslinking

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TRANSCRIPTION FACTOR; DNA BINDING PROTEIN; GLUTAMIC ACID; I KAPPA B; I KAPPA B BETA; NERVE PROTEIN;

ANIMAL CELL; ARTICLE; BRAIN; CROSS LINKING; DNA PROBE; ELECTROPHORETIC MOBILITY; GENETIC TRANSCRIPTION; NERVE CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; ANIMAL; BINDING COMPETITION; CELL CULTURE; CHEMISTRY; CYTOLOGY; DIMERIZATION; DRUG EFFECT; GLIA; ISOLATION AND PURIFICATION; METABOLISM; NERVE CELL; OLIGONUCLEOTIDE PROBE; PHYSIOLOGY; RAT; SPRAGUE DAWLEY RAT; ULTRAVIOLET RADIATION;

ANIMALS; BINDING, COMPETITIVE; CELLS, CULTURED; DIMERIZATION; DNA-BINDING PROTEINS; GLUTAMIC ACID; I-KAPPA B PROTEINS; NERVE TISSUE PROTEINS; NEUROGLIA; NEURONS; NF-KAPPA B; OLIGONUCLEOTIDE PROBES; RATS; RATS, SPRAGUE-DAWLEY; ULTRAVIOLET RAYS;

EID: 0033586686     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(99)00091-1     Document Type: Article

References (39)

1. Baeuerle P.A., Baichwal V.R. NF-κB as a frequent target for immunosuppressive and anti-inflammatory molecules. Adv. Immunol. 65:1997;111-137.
2. Baeuerle P.A., Baltimore D. Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-κB transcription factor. Cell. 53:1988;211-217.
3. Bakalkin G.Y., Yakovleva T., Terenius L. NF-κB-like factors in the murine brain. Developmentally-regulated and tissue-specific expression. Mol. Brain Res. 20:1993;137-146.
4. Bakalkin G.Y., Yakovleva T., Terenius L. Prodynorphin gene expression relates to NF-κB factors. Mol. Brain Res. 24:1994;301-312.
5. Baldwin A.S. Jr. The NF-κB and IκB proteins: new discoveries and insights. Ann. Rev. Immunol. 14:1996;649-683.
6. Barger S.W., Fiscus R.R., Ruth P., Hofmann F., Mattson M.P. The role of cyclic GMP in the regulation of neuronal calcium and survival by secreted forms of β-amyloid precursor. J. Neurochem. 64:1995;2087-2096.
7. Barger S.W., Harmon A.D. Microglial activation by secreted Alzheimer amyloid precursor protein and modulation by apolipoprotein E. Nature. 388:1997;878-881.
8. 2+ accumulation. Proc. Natl. Acad. Sci. USA. 92:1995;9328-9332.
9. Barger S.W., Mattson M.P. Induction of neuroprotective κB-dependent transcription by secreted form of the Alzheimer's β-amyloid precursor. Mol. Brain Res. 40:1996;116-126.
10. Barger S.W., Mattson M.P. Participation of gene expression in the protection against amyloid β-peptide toxicity by the β-amyloid precursor protein. Ann. NY Acad. Sci. 777:1996;303-308.
11. Cauley K., Verma I.M. κB enhancer-binding complexes that do not contain NF-κB are developmentally regulated in mammalian brain. Proc. Natl. Acad. Sci. USA. 91:1994;390-394.
12. Corradin S.B., Mauel J., Donini S.D., Quattrocchi E., Ricciardi-Castagnoli P. Inducible nitric oxide synthase activity of cloned murine microglial cells. Glia. 7:1993;255-262.
13. Diehl J.A., Hannink M. Identification of a C/EBP-Rel complex in avian lymphoid cells. Mol Cell Biol. 14:1994;6635-6646.
14. Drew P.D., Franzoso G., Becker K.G., Bours V., Carlson L.M., Siebenlist U., Ozato K. NFκB and interferon regulatory factor 1 physically interact and synergistically induce major histocompatibility class I gene expression. J. Interferon Cytokine Res. 15:1995;1037-1045.
15. Grilli M., Goffi F., Memo M., Spano P. Interleukin-1β and glutamate activate the NF-κB/Rel binding site from the regulatory region of the amyloid precursor protein gene in primary neuronal cultures. J. Biol. Chem. 271:1996;15002-15007.
16. Guerrini L., Blasi F., Denis-Donini S. Synaptic activation of NF-κB by glutamate in cerebellar granule neurons in vitro. Proc. Natl. Acad. Sci. USA. 92:1995;9077-9081.
17. Guerrini L., Molteni A., Wirth T., Kistler B., Blasi F. Glutamate-dependent activation of NF-κB during mouse cerebellum development. J. Neurosci. 17:1997;6057-6063.
18. Hunter T., Karin M. The regulation of transcription by phosphorylation. Cell. 70:1992;375-387.
19. Kaltschmidt B., Uherek M., Volk B., Baeuerle P.A., Kaltschmidt C. Transcription factor NF-κB is activated in primary neurons by amyloid peptides and in neurons surrounding early plaques from patients with Alzheimer's disease. Proc. Natl. Acad. Sci. USA. 94:1997;2642-2647.
20. Kaltschmidt C., Kaltschmidt B., Baeuerle P.A. Stimulation of ionotropic glutamate receptors activates transcription factor NF-κB in primary neurons. Proc. Natl. Acad. Sci. USA. 92:1995;9618-9622.
21. Kaltschmidt C., Kaltschmidt B., Neumann H., Wekerle H., Baeuerle P.A. Constitutive NF-κB activity in neurons. Mol Cell Biol. 14:1994;3981-3992.
22. Korner M., Rattner A., Mauxion F., Sen R., Citri Y. A brain-specific transcription activator. Neuron. 3:1989;563-572.
23. Kunsch C., Ruben S.M., Rosen C.A. Selection of optimal κB/Rel DNA-binding motifs: interaction of both subunits of NF-κB with DNA is required for transcriptional activation. Mol. Cell. Biol. 12:1992;4412-4421.
24. Mao X., Barger S.W. Neuroprotection by dehydroepiandrosterone-sulfate: involvement of an NFκB-like factor. NeuroReport. 9:1998;759-763.
25. Mao X., Moerman A.M., Chang L.W., Barger S.W. Toxic glutamate treatment diminishes a κB-binding factor activity in rat primary neurons. Soc. Neurosci. Abstr. 24:1998;424.12.
26. Meberg P.J., Kinny W.R., Valcourt E.G., Routtenberg A. Gene expression of the transcription factor NF-κB in hippocampus: regulation by synaptic activity. Mol. Brain Res. 38:1996;179-190.
27. Merola M., Blanchard B., Tovey M.G. The κB enhancer of the human interleukin-6 promoter is necessary and sufficient to confer an IL-1β and TNFα response in transfected human cell lines: requirement for members of the C/EBP family for activity. J. Interferon Cytokine Res. 16:1996;783-798.
28. Moerman A.M., Mao X., Barger S.W. Characterization of a κB-binding transcription factor in neurons: distinction from NFκB. Soc. Neurosci. Abstr. 24:1998;1068.
29. Pleasure S.J., Page C., Lee V.M. Pure, postmitotic, polarized human neurons derived from NTera 2 cells provide a system for expressing exogenous proteins in terminally differentiated neurons. J. Neurosci. 12:1992;1802-1815.
30. Rattner A., Korner M., Walker M.D., Citri Y. NF-κB activates the HIV promoter in neurons. EMBO J. 12:1993;4261-4267.
31. Schmid R.M., Liptay S., Betts J.C., Nabel G.J. Structural and functional analysis of NF-κB. Determinants of DNA binding specificity and protein interaction. J. Biol. Chem. 269:1994;32162-32167.
32. Schousboe A., Sonnewald U., Civenni G., Gegelashvili G. Role of astrocytes in glutamate homeostasis. Implications for excitotoxicity. Adv. Exp. Med. Biol. 429:1997;195-206.
33. Selinfreund R.H., Barger S.W., Pledger W.J., Van Eldik L.J. The neurotrophic protein S100β stimulates glial cell proliferation. Proc. Natl. Acad. Sci. USA. 88:1991;3554-3558.
34. Sha W.C., Liou H., Tuomanen E.I., Baltimore D. Targeted disruption of the p50 subunit of NF-κB leads to multifocal defects in immune responses. Cell. 80:1995;321-330.
35. Stein B., Cogswell P.C., Baldwin A.S. Jr. Functional and physical associations between NF-κB and C/EBP family members: a Rel domain-bZIP interaction. Mol. Cell. Biol. 13:1993;3964-3974.
36. Thompson J.E., Phillips R.J., Erdjument-Bromage H., Tempst P., Ghosh S. IκB-β regulates the persistent response in a biphasic activation of NF-κB. Cell. 80:1995;573-582.
37. Togashi H., Sasaki M., Frohman E., Taira E., Ratan R.R., Dawson T.M., Dawson V.A. Neuronal (type I) nitric oxide synthase regulates nuclear factor κB activity and immunologic (type II) nitric oxide synthase expression. Proc. Natl. Acad. Sci. USA. 94:1997;2676-2680.
38. Toledano M.B., Ghosh D., Trinh F., Leonard W.J. N-terminal DNA-binding domains contribute to differential DNA-binding specificities of NF-κB p50 and p65. Mol. Cell. Biol. 13:1993;852-860.
39. Zhang Z., Fuller G.M. The competitive binding of STAT3 and NF-κB on an overlapping DNA binding site. Biochem. Biophys. Res. Commun. 237:1997;90-94.