메뉴 건너뛰기




Volumn 7, Issue 10, 1996, Pages 1281-1306

Gene therapy for aids using retroviral mediated gene transfer to deliver hiv-1 antisense tar and transdominant rev protein genes to syngeneic lymphocytes in hiv-1 infected identical twins

Author keywords

[No Author keywords available]

Indexed keywords

REV PROTEIN;

EID: 0030594579     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/hum.1996.7.10-1281     Document Type: Article
Times cited : (63)

References (49)
  • 1
    • 0025713040 scopus 로고
    • Estimates of HJV-1 prevalence and projected AIDS cases: Summary of a workshop October 31-November 1, 1989
    • Estimates of HJV-1 prevalence and projected AIDS cases: summary of a workshop October 31-November 1, 1989. MMWR 39:110-119(1990).
    • (1990) MMWR , vol.39 , pp. 110-119
  • 2
    • 0021261510 scopus 로고
    • Frequent detection and isolation of cytopathic retrovirus (HTLV-ni) from patients with AIDS and at risk for AIDS
    • Gallo RC, Salahuddin SZ, Popovic M, et al. Frequent detection and isolation of cytopathic retrovirus (HTLV-ni) from patients with AIDS and at risk for AIDS. Science 224:500 (1984).
    • (1984) Science , vol.224 , pp. 500
    • Gallo, R.C.1    Sz Salahuddin2    Popovic, M.3
  • 3
    • 0020596551 scopus 로고
    • Isolation of a Tlymphotropic retrovirus from a patients at risk for acquired immune deficiency syndrome
    • Barre-Sinoussi F, Nugeyre M, Dauguet C, et al. Isolation of a Tlymphotropic retrovirus from a patients at risk for acquired immune deficiency syndrome. Science 220:868 (1983).
    • (1983) Science , vol.220 , pp. 868
    • Barre-Sinoussi, F.1    Nugeyre, M.2    Dauguet, C.3
  • 4
    • 0021237243 scopus 로고
    • Isolation, and continuous production of cytopathic retrovirus (HTLV-Hf) from patients with AIDS and pre-AIDS
    • Popovic M, Sarngadbaron MO, Read E, Gallo RC. Detection, isolation, and continuous production of cytopathic retrovirus (HTLV-Hf) from patients with AIDS and pre-AIDS. Science 224:497 (1984).
    • (1984) Science , vol.224 , pp. 497
    • Popovic, M.1    Sarngadbaron, M.O.2    Read, E.3    Detection, G.R.C.4
  • 5
    • 0023868337 scopus 로고
    • Epidemiology of HTV-1 infection and AIDS in the United States
    • Curran JW, Jaffe HW, Hardy AM. Epidemiology of HTV-1 infection and AIDS in the United States. Science 239:610 (1988).
    • (1988) Science , vol.239 , pp. 610
    • Curran, J.W.1    Jaffe, H.W.2    Hardy, A.M.3
  • 7
    • 0023268502 scopus 로고
    • The efficacy of azidothymidine in the treatment of patients with AIDS and ATDS-related complex
    • Fischl MA, Richman DD, Grieco MH, et al. The efficacy of azidothymidine in the treatment of patients with AIDS and ATDS-related complex. N Engl J Med 317:185-191 (1987).
    • (1987) N Engl J Med , vol.317 , pp. 185-191
    • Fischl, M.A.1    Richman, D.D.2    Grieco, M.H.3
  • 8
    • 0025238899 scopus 로고
    • Zidovudine in asymptomatic human immunodeficiency virus infection
    • Volberding PA, Lagakos SW, Koch MA, et al. Zidovudine in asymptomatic human immunodeficiency virus infection. N Engl J Med 322:941-949 (1990).
    • (1990) N Engl J Med , vol.322 , pp. 941-949
    • Volberding, P.A.1    Lagakos, S.W.2    Koch, M.A.3
  • 9
    • 0025314920 scopus 로고
    • The safety and efficacy of zidovudine (AZT) in the treatment of subjects with mildly symptomatic human immunodeficiency virus type 1 (HTV) infection
    • Fischl MA, Richman DD, Hansen N, et al. The safety and efficacy of zidovudine (AZT) in the treatment of subjects with mildly symptomatic human immunodeficiency virus type 1 (HTV) infection. Ann Intern Med 112:727-737 (1990).
    • (1990) Ann Intern Med , vol.112 , pp. 727-737
    • Fischl, M.A.1    Richman, D.D.2    Hansen, N.3
  • 10
    • 0025233777 scopus 로고
    • Early treatment for HTV: The time has come
    • Friedland GH. Early treatment for HTV: the time has come. N Engl i Med 322:1000-1002 (1990).
    • (1990) N Engl I Med , vol.322 , pp. 1000-1002
    • Friedland, G.H.1
  • 11
    • 0025353175 scopus 로고
    • Zidovudine for early human immunodeficiency virus (HTV) infection: Who, when, and how?
    • Ruedy J, Schlechter M, Montaner JSG. Zidovudine for early human immunodeficiency virus (HTV) infection: Who, when, and how? Ann Intern Med 112:721-723 (1990).
    • (1990) Ann Intern Med , vol.112 , pp. 721-723
    • Ruedy, J.1    Schlechter, M.2    Montaner, J.S.G.3
  • 12
    • 0026515454 scopus 로고
    • Combination therapy for HTV-1 infection: Getting closer
    • Fauci AS. Combination therapy for HTV-1 infection: getting closer. Ann Intern Med 116:85-86 (1992).
    • (1992) Ann Intern Med , vol.116 , pp. 85-86
    • Fauci, A.S.1
  • 13
    • 0024466565 scopus 로고
    • Prolonged zidovudine therapy in patients with AIDS and advanced AIDS-related complex. AZT Collaborative Working Group
    • Fischl MA, Richman DD, Causey DM, et al. Prolonged zidovudine therapy in patients with AIDS and advanced AIDS-related complex. AZT Collaborative Working Group. JAMA 262:2405-2410 (1989).
    • (1989) JAMA , vol.262 , pp. 2405-2410
    • Fischl, M.A.1    Richman, D.D.2    Causey, D.M.3
  • 14
    • 0024805742 scopus 로고
    • Quantitation of human immunodeficiency virus type 1 in the blood of infected persons
    • Ho DD, Moudgil T, Alam M. Quantitation of human immunodeficiency virus type 1 in the blood of infected persons. N Engl J Med 321:1621-1625 (1989).
    • (1989) N Engl J Med , vol.321 , pp. 1621-1625
    • Ho, D.D.1    Moudgil, T.2    Alam, M.3
  • 15
    • 0023266214 scopus 로고
    • The toxicity of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex: A double-blind, placebo-controlled trial
    • Richman DD, Fischl MA, Grieco MH, et al. The toxicity of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex: a double-blind, placebo-controlled trial. N Engl J Med 317:192-197 (1987).
    • (1987) N Engl J Med , vol.317 , pp. 192-197
    • Richman, D.D.1    Fischl, M.A.2    Grieco, M.H.3
  • 16
    • 0024508058 scopus 로고
    • HTV-1 with reduced sensitivity to zidovudine (AZT) isolated during prolonged therapy
    • Larder BA, Darby G, Richman DD. HTV-1 with reduced sensitivity to zidovudine (AZT) isolated during prolonged therapy. Science 243:1731-1734(1989).
    • (1989) Science , vol.243 , pp. 1731-1734
    • Larder, B.A.1    Darby, G.2    Richman, D.D.3
  • 17
    • 0018350673 scopus 로고
    • Bone marrow transplantation for severe combined immunodeficiency disease
    • Kenny AB, Hitzig WH. Bone marrow transplantation for severe combined immunodeficiency disease. Reported from 1968 to 1977. EUT J Pediatr 131:155-177 (1979).
    • (1979) Reported from 1968 to 1977. EUT J Pediatr , vol.131 , pp. 155-177
    • Kenny, A.B.1    Hitzig, W.H.2
  • 18
    • 0023573880 scopus 로고
    • Bone marrow transplantation in the treatment of primary immunodeficiencies
    • Vossen JM. Bone marrow transplantation in the treatment of primary immunodeficiencies. Ann Clin Res 19:285-292 (1987).
    • (1987) Ann Clin Res , vol.19 , pp. 285-292
    • Vossen, J.M.1
  • 19
    • 0017642631 scopus 로고
    • Severe combined immunodeficiency disease. Characterization of the disease and results of transplantation
    • Boron MM, Rimm AA. Severe combined immunodeficiency disease. Characterization of the disease and results of transplantation. JAMA 238:591-600 (1977).
    • (1977) JAMA , vol.238 , pp. 591-600
    • Boron, M.M.1    Rimm, A.A.2
  • 20
    • 0023796245 scopus 로고
    • Anti-retroviral effects of interferonalpha in AIDS-associated Kaposi's sarcoma
    • Lane HC, Kovacs JA, Feinberg J. Anti-retroviral effects of interferonalpha in AIDS-associated Kaposi's sarcoma. Lancet 2:1218-1222 (1988).
    • (1988) Lancet , vol.2 , pp. 1218-1222
    • Lane, H.C.1    Kovacs, J.A.2    Feinberg, J.3
  • 21
    • 0020578618 scopus 로고
    • Interleukin-2 enhances the depressed natural killer and cytomegalovirus-specific cytotoxic activities of lymphocytes from patients with the acquired immunodeficiency syndrome
    • Rook AH, Masur H, Lane HC, et al. Interleukin-2 enhances the depressed natural killer and cytomegalovirus-specific cytotoxic activities of lymphocytes from patients with the acquired immunodeficiency syndrome. J Clin Invest 72:398-403 (1987).
    • (1987) J Clin Invest , vol.72 , pp. 398-403
    • Rook, A.H.1    Masur, H.2    Lane, H.C.3
  • 22
    • 0021612611 scopus 로고
    • Partial immune reconstitution in a patient with the acquired immunodeficiency syndrome
    • Lane HC, Masur H, Longo D, et al. Partial immune reconstitution in a patient with the acquired immunodeficiency syndrome. N Engl J Med 311:1099-1103 (1984).
    • (1984) N Engl J Med , vol.311 , pp. 1099-1103
    • Lane, H.C.1    Masur, H.2    Longo, D.3
  • 23
    • 19144366661 scopus 로고
    • Bone marrow transplantation from identical twins in the treatment of AIDS and Kaposi's sarcoma
    • Mitsuyasu R, Volberding P, Groopman J, et al. Bone marrow transplantation from identical twins in the treatment of AIDS and Kaposi's sarcoma [Abstract]. J Cell Biochem 8A:22 (1987).
    • (1987) J Cell Biochem , vol.8 , pp. 22
    • Mitsuyasu, R.1    Volberding, P.2    Groopman, J.3
  • 25
    • 0020678205 scopus 로고
    • Lymphocyte transfusion in case of acquired immunodeficiency syndrome [Letter]
    • Davis KC, Hayward A, Ozturk G, et al. Lymphocyte transfusion in case of acquired immunodeficiency syndrome [Letter]. Lancet 1:599-600 (1983).
    • (1983) Lancet , vol.1 , pp. 599-600
    • Davis, K.C.1    Hayward, A.2    Ozturk, G.3
  • 26
    • 0023368487 scopus 로고
    • Clinical and immunological restoration in patients with AIDS after marrow transplantation, using lymphocyte transfusions from the marrow donor
    • Vilmer E, Rhodes-Feuillette A, Rabian C, et al. Clinical and immunological restoration in patients with AIDS after marrow transplantation, using lymphocyte transfusions from the marrow donor. Transplantation 44:25-29 (1987).
    • (1987) Transplantation , vol.44 , pp. 25-29
    • Vilmer, E.1    Rhodes-Feuillette, A.2    Rabian, C.3
  • 27
    • 0023920372 scopus 로고
    • Syngeneic leukocytes together with suramin failed to improve immunodeficiency in a case of transfusion-associated AIDS after syngeneic bone marrow transplantation
    • Verdonck LF, de Gast GC, Lange JM, et al. Syngeneic leukocytes together with suramin failed to improve immunodeficiency in a case of transfusion-associated AIDS after syngeneic bone marrow transplantation. Blood 71:666-671 (1988).
    • (1988) Blood , vol.71 , pp. 666-671
    • Verdonck, L.F.1    De Gast, G.C.2    Lange, J.M.3
  • 28
    • 0025011944 scopus 로고
    • Syngeneic bone marrow transplantation and adoptive transfer of peripheral blood lymphocytes combined with zidovudine in human immunodeficiency virus (HTV) infection
    • Lane HC, Zunich KM, Wilson W, et al. Syngeneic bone marrow transplantation and adoptive transfer of peripheral blood lymphocytes combined with zidovudine in human immunodeficiency virus (HTV) infection. Ann Intern Med 113:512-519 (1990).
    • (1990) Ann Intern Med , vol.113 , pp. 512-519
    • Lane, H.C.1    Zunich, K.M.2    Wilson, W.3
  • 31
    • 0024382709 scopus 로고
    • Functional dissection of the HTV-1 Rev trans-activator: Derivation of a trans-dominant represser of Rev function
    • Malim, M.H., Bohnlein, S., Hauber, J., and Cullen, B.R. 1989. Functional dissection of the HTV-1 Rev trans-activator: derivation of a trans-dominant represser of Rev function. Cell 58:205-214.
    • (1989) Cell , vol.58 , pp. 205-214
    • Malim, M.H.1    Bohnlein, S.2    Hauber, J.3    Cullen, B.R.4
  • 33
    • 0028148012 scopus 로고
    • A molecular genetic intervention for AIDS-Effects of a transdominant negative form of Rev
    • Nabel, G.J., Fox, B.A., Post, L., Thompson, C.B., and Woffendin, C. 1994. A molecular genetic intervention for AIDS-Effects of a transdominant negative form of Rev. Hum. Gene Ther. 5:79-92.
    • (1994) Hum. Gene Ther. , vol.5 , pp. 79-92
    • Nabel, G.J.1    Fox, B.A.2    Post, L.3    Thompson, C.B.4    Woffendin, C.5
  • 34
    • 0027981916 scopus 로고
    • Evidence that HTV-1 Rev directly promotes the nuclear export of unspliced RNA
    • Fisher, U., Meyer, S., Teufel, M., Heckel, C., Luhrmann, R., and Rautmann, G. 1994. Evidence that HTV-1 Rev directly promotes the nuclear export of unspliced RNA. The EMBO J. 13 (17):4105-4112.
    • (1994) The EMBO J. , vol.13 , Issue.17 , pp. 4105-4112
    • Fisher, U.1    Meyer, S.2    Teufel, M.3    Heckel, C.4    Luhrmann, R.5    Rautmann, G.6
  • 35
    • 0026608633 scopus 로고
    • Transdominant inhibition of human immunodeficiency virus type 1 Rev occurs through formation of inactive protein complexes
    • Hope, T.J., Klein, N.P., Elder, M.E., & Parslow, T.G. 1992. Transdominant inhibition of human immunodeficiency virus type 1 Rev occurs through formation of inactive protein complexes. J. Virol. 66:1849-1855.
    • (1992) J. Virol. , vol.66 , pp. 1849-1855
    • Hope, T.J.1    Klein, N.P.2    Elder, M.E.3    Parslow, T.G.4
  • 38
    • 0025344596 scopus 로고
    • Tat protein of HIV-1 stimulates growth of cells derived from Kaposi's sarcoma lesions of AIDS patients
    • Ensoli, B., Barillari, G., Salahuddin, S.Z., Gaüo, R.C., and WongStaal, F. 1990. Tat protein of HIV-1 stimulates growth of cells derived from Kaposi's sarcoma lesions of AIDS patients. Nature 344:84-86.
    • (1990) Nature , vol.344 , pp. 84-86
    • Ensoli, B.1    Barillari, G.2    Salahuddin, S.Z.3    Gaüo, R.C.4    Wongstaal, F.5
  • 39
    • 0025867199 scopus 로고
    • Human immunodeficiency virus induction of malignant transformation in human B lymphocytes
    • Laurence, J., and Astrin, S.M. 1991. Human immunodeficiency virus induction of malignant transformation in human B lymphocytes. Proc. Natl. Acad. Sei. U.S.A. 88:7635-7639.
    • (1991) Proc. Natl. Acad. Sei. U.S.A. , vol.88 , pp. 7635-7639
    • Laurence, J.1    Astrin, S.M.2
  • 41
    • 0026706196 scopus 로고
    • Human immuno-deficiency virus-infected monocyte-derived macrophages express surface GP120 and fuse with CD4 lymphoid cells in vitro: A possible mechanism of T lymphocyte depletion in vivo
    • Crowe, S.M., Mills, J., Elbeik, T., et al: 1992. Human immuno-deficiency virus-infected monocyte-derived macrophages express surface GP120 and fuse with CD4 lymphoid cells in vitro: A possible mechanism of T lymphocyte depletion in vivo. Clin Immunol Immunopathol 65:143-151.
    • (1992) Clin Immunol Immunopathol , vol.65 , pp. 143-151
    • Crowe, S.M.1    Mills, J.2    Elbeik, T.3
  • 42
    • 0026784923 scopus 로고
    • Crosslinking CD4 by human immunodeficiency virus gp!20 primes T cells for activation-induced apoptosis
    • Banda, N.K., Bernier, J., Kurahara, D.K., et al: 1992. Crosslinking CD4 by human immunodeficiency virus gp!20 primes T cells for activation-induced apoptosis. J. Exp. Med. 176: 1099-1106.
    • (1992) J. Exp. Med. , vol.176 , pp. 1099-1106
    • Banda, N.K.1    Bernier, J.2    Kurahara, D.K.3
  • 43
    • 0027447509 scopus 로고
    • FflV-1 envelope protein-induced neuronal damage and retardation of behavioral development hi rat neonates
    • HiU, J.M., Mervis, R.F., Avidor, R., et al: 1993. fflV-1 envelope protein-induced neuronal damage and retardation of behavioral development hi rat neonates. Brain Res 603:222-233.
    • (1993) Brain Res , vol.603 , pp. 222-233
    • Hiu, J.M.1    Mervis, R.F.2    Avidor, R.3
  • 44
    • 0024988334 scopus 로고
    • Gene transfer into humans-immunotherapy of patients with advanced melanoma, using tumor-infillraling lymphocytes modified by retroviral gene iransduction
    • Rosenberg SA, Aebersold P, Cornelia K, el al. Gene transfer into humans-immunotherapy of patients with advanced melanoma, using tumor-infillraling lymphocytes modified by retroviral gene iransduction. New Engl J Med 323:570-578 (1990).
    • (1990) New Engl J Med , vol.323 , pp. 570-578
    • Rosenberg, S.A.1    Aebersold, P.2    Cornelia, K.3
  • 45
    • 0026101660 scopus 로고
    • Large scale séparation of peripheral blood monocytes: Influence of elutriation medium and storage conditions on inflammatory mediator release
    • Abrahamsen TG, Carter CS, Rubin M, et al. Large scale séparation of peripheral blood monocytes: Influence of elutriation medium and storage conditions on inflammatory mediator release. J Clin Apheresis 6:48-53, 1991.
    • (1991) J Clin Apheresis , vol.6 , pp. 48-53
    • Abrahamsen, T.G.1    Carter, C.S.2    Rubin, M.3
  • 46
    • 0023918549 scopus 로고
    • Technical aspecls of lymphokine-activated killer production
    • Carter CS, Leilman SF, Cullis H, el al. Technical aspecls of lymphokine-activated killer production. J Clin Apheresis 4:113-117, 1988.
    • (1988) J Clin Apheresis , vol.4 , pp. 113-117
    • Carter, C.S.1    Leilman, S.F.2    Cullis, H.3
  • 47
    • 0023764189 scopus 로고
    • A simplified automated procedure for generation of lymphokine-activated killer cells for use in clinical trials
    • Aebersold P, Carter CS, Hyatl C, el al. A simplified automated procedure for generation of lymphokine-activated killer cells for use in clinical trials. J Immunol Methods 112:1-7, 1988.
    • (1988) J Immunol Methods , vol.112 , pp. 1-7
    • Aebersold, P.1    Carter, C.S.2    Hyatl, C.3
  • 48
    • 0023278405 scopus 로고
    • Developmenl of an automated closed system for generation of human lymphokineactivated killer (LAK) cells for use in adoptive immunotherapy
    • Muul LM, Nason-Burchenal K, Carter CS, el al. Developmenl of an automated closed system for generation of human lymphokineactivated killer (LAK) cells for use in adoptive immunotherapy. J Immunol Methods 101:171-181, 1987.
    • (1987) J Immunol Methods , vol.101 , pp. 171-181
    • Muul, L.M.1    Nason-Burchenal, K.2    Carter, C.S.3
  • 49
    • 0023228499 scopus 로고
    • Use of a continuous-flow cell separator in density gradient isolation of lymphocytes
    • Carter CS, Leilman SF, Cullis H, el al. Use of a continuous-flow cell separator in density gradient isolation of lymphocytes. Transfusion 27:362-365, 1987.
    • (1987) Transfusion , vol.27 , pp. 362-365
    • Carter, C.S.1    Leilman, S.F.2    Cullis, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.