Herbal remedies for asthma treatment: Between myth and reality

Drugs of Today

Volumn 38, Issue 4, 2002, Pages 265-303

  Szelenyi, Istvan ^a   Brune, Kay ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANETHOLE; AZELASTINE; BAKUMONDOTO; BELLADONNA ALKALOID; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BROMHEXINE; CANNABIS; CHAMOMILE; CURCUMIN; DEXTROMETHORPHAN; DLH 721; GLUCOCORTICOID; HERBACEOUS AGENT; MAO BUSHI SAISHIN TO; OXATOMIDE; PEPPERMINT; PREDNISOLONE; QING FEI TANG; RYO KAN KYOMI SIN GE NIN TO; SAI REI TO; SAIBOKU TO; SANGUINARINE; SHO SEIRYU TO; STEROID; STRAMONIUM; TRIKATU; UNCLASSIFIED DRUG; UNINDEXED DRUG; WU HU TANG; XIAO CHAI HU TANG; PLANT MEDICINAL PRODUCT;

ADHATODA VASICA; ALBIZZIA LEBBECK; ALTERNATIVE MEDICINE; AMMI VISNAGA; ANDROGRAPHIS PANICULATA; ASTHMA; BERBERIS VULGARIS; BOSWELLIA SERRATA; CEDRUS DEODARA; CHAMAEMILUM NOBILE; CLERODENDRUM PETASITES; CLINICAL TRIAL; CODONOPSIS PILOSULA; COFFEE; COLEUS FORSKOHLII; CURCUMA LONGA; DATURA STRAMONIUM; DRUG EFFICACY; DRUG SAFETY; EPHEDRA SINICA; ERIODICTYON GLUTINOSUM; EUCALYPTUS GLOBULUS; EUPHRASIA OFFICINALIS; FENNEL; GALPHIMIA GLAUCA; GARLIC; HERB; HERBAL MEDICINE; HUMAN; NONHUMAN; ONION; PEPPER; PINEAPPLE; REVIEW; SIDE EFFECT; SUPPLEMENTATION; TEA; ANIMAL; CHEMISTRY; CLASSIFICATION; INDIA; JAPAN; MEDICINAL PLANT; PHYTOTHERAPY;

ANIMAL; ASTHMA; DRUGS, CHINESE HERBAL; HUMAN; INDIA; JAPAN; PHYTOTHERAPY; PLANT PREPARATIONS; PLANTS, MEDICINAL; ANIMALS; HUMANS;

EID: 0036228457     PISSN: 16993993     EISSN: 16994019     Source Type: Journal    
DOI: 10.1358/dot.2002.38.4.668337     Document Type: Review

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180. An immunomodulatory polysaccharide-rich substance from the fruit juice of Morinda citrifolia (noni) with antitumour activity
181. Stimulation of ultraviolet-induced apoptosis of human fibroblast UVr-1 cells by tyrosine kinase inhibitors
182. High-performance liquid chromatographic determination with photodiode array detection of ellagic acid in fresh and processed fruits
183. A novel non-peptide endothelin antagonist isolated from bayberry, Myrica cerifera
184. Antiallergic activity of arbortristosides from Nycanthus arbortristis
185. Bronchial asthma: Information on phytotherapy with essential fatty acids. Interactions between essential fatty acids and steroid hormones
186. Inhibitory effects of traditional Chinese medicine Shimotsu-to and its included crude fractions on adjuvant-induced chronic inflammation of mice
187. Peony tincture in the complex treatment of allergic dermatoses
188. Passionflower in the treatment of generalized anxiety: A pilot double-blind randomized controlled trial with oxazepam
189. Pharmacological effects of zisu and baisu
190. Inhibitory effect of mast cell-mediated immediate-type allergic reactions in rats by Perilla frutescens
191. Effect of oral treatment of Perilla frutescens and its constituents on type-1 allergy in mice
192. Effects of perilla seed oil supplementation on leukotriene generation by leucocytes in patients with asthma associated with lipometabolism
193. Effects of dietary supplementation with n-3 fatty acids compared with n-6 fatty acids on bronchial asthma
194. Gastro-protective effects by extracts of Petasites hybridus: The role of inhibition of peptido-leukotriene synthesis
195. Identification and characterization of inhibitors of peptido-leukotriene-synthesis from Petasites hybridus
196. Differential inhibition of inflammatory effector functions by petasin, isopetasin and neopetasin in human eosinophils
197. Role of petasin in the potential anti-inflammatory activity of a plant extract of petasites hybridus
198. Effects of extracts and of individual components from Petasites on prostaglandin synthesis in cultured skin fibroblasts and on leucotriene synthesis in isolated human peripheral leucocytes
199. Relaxant effects of petasins in isolated guinea pig trachea and their structure-activity relationships
200. Mechanisms of relaxant action of S-petasin and S-isopetasin, sesquiterpenes of Petasites formosanus, in isolated guinea pig trachea
201. Study on clinical properties and mechanisms of action of Petasites in bronchial asthma and chronic obstructive bronchitis
202. Petasites hybridus
203. Petasites hybridus: A tool for interdisciplinary research in phytotherapy
204. Pyrrolizidine alkaloids in Petasites hybridus L. and P. albus L
205. Method for the reduction of pyrrolizidine alkaloids from medicinal plant extracts
206. Picrorhiza kurroa
207. Picroliv, picroside-I and kutkoside from Picrorhiza kurroa are scavengers of superoxide anions
208. Effect of DSCG and P. kurroa root powder on sensitivity of guinea pigs to histamine and sympathomimetic amines
209. Anti-allergic and anti-anaphylactic activity of picroliv - A standardised iridoid glycoside fraction of Picrorhiza kurroa
210. Picroliv - A natural product protects cells and regulates the gene expression during hypoxia/reoxygenation
211. Metabolic activation of natural phenols into selective oxidative burst agonists by activated human neutrophils
212. Metabolic activation of phenols by stimulated neutrophils: A concept for a selective type of anti-inflammatory drug
213. Glucocorticoid-induced apoptotic pathways in eosinophils: Comparison with glucocorticoid-sensitive leukemia cells
214. Apocynin and 1400 W prevents airway hyperresponsiveness during allergic reactions in mice
215. Antiasthmatic effects of Picrorhiza kurroa: Androsin prevents allergen- and PAF-induced bronchial obstruction in guinea pigs
216. Clinical trials on Picrorhiza kurroa
217. Study of Picrorhiza kurroa (PK 300) in cases of bronchial asthma
218. Pulmonary function tests in bronchial asthma (study during symptom free period before and after a bronchodilator)
219. A preliminary clinical trial of Picrorrhiza kurroa in bronchial asthma
220. Preliminary report of use of Picrorrhiza kurroa root in bronchial asthma
221. Picrorrhiza kurroa in bronchial asthma
222. Effect of various phytotherapeutic expectorants on mucociliary transport
223. Antioxidant activity and biologic properties of a procyanidin-rich extract from pine (Pinus maritima) bark, pycnogenol
224. Pycnogenol inhibits tumor necrosis factor-α-induced nuclear factor kB activation and adhesion molecule expression in human vascular endothelial cells
225. Anti-inflammatory activity of piperine
226. Inhibition of lipid peroxidation by piperine during experimental inflammation in rats
227. Comparative anti-nociceptive, anti-inflammatory and toxicity profile of nimesulide vs nimesulide and piperine combination
228. Efficacy of piper iongum in childhood asthma
229. Amrita Bindu - A salt-spice-herbal health food supplement for the prevention of nitrosamine induced depletion of antioxidants
230. On the anti-inflammatory and anti-phospholipase A(2) activity of extracts from lanostane-rich species
231. Effect of the basidiomycete Poria cocos on experimental dermatitis and other inflammatory conditions
232. 3-β-p-hydroxybenzoyldehydrotumulosic acid from Poria cocos, and its anti-inflammatory effect
233. Suppression of tumor necrosis factor-alpha, interleukin-1 beta, interleukin-6 and granulocyte-monocyte colony stimulating factor secretion from human monocytes by an extract of Poria cocos
234. Antioxidant activity of qizhu tang
235. Characterization of gamma-iinolenic acid in Ribes seed
236. Comparative effects of total flavonoids extracted from Ribes nigrum leaves, rutin and isoquercitrin on biosynthesis and release of prostaglandins in the ex vivo rabbit heart
237. Anti-inflammatory evaluation of a hydroalcoholic extract of black currant leaves (Ribes nigrum)
238. Pharmacology of rosemary (Rosmarinus officinalis Linn.) and its therapeutic potentials
239. Antioxidant capacities and phenolics levels of French wines from different varieties and vintages
240. Influence of cyclooxygenase and lipoxygenase inhibitors on oxidative stress-induced lung injury
241. Caffeic acid is a selective inhibitor for leukotriene biosynthesis
242. Effects of catecholamines on eicosanoid synthesis with special reference to prostanoid/leukotriene ratio
243. New lipoxygenase inhibitors isolated from Chinese plants. Development of new anti-allergic drugs
244. Studies on the activities of tannins and related compounds, X. Effects of caffeetannins and related compounds on arachidonate metabolism in human polymorphonuclear leukocytes
245. Allergic contact dermatitis from rosemary (Rosmarinus officinalis L.)
246. Potent anti-inflammatory activities of hydroalcoholic extract from aerial parts of Stachys inflata on rats
247. Sanguinarine (pseudochelerythrine) is a potent inhibitor of NF-κB activation, IκBa phosphorylation, and degradation
248. Influence of natural and synthetic compounds on cell surface expression of cell adhesion molecules, ICAM-1 and VCAM-1
249. Inhibitory effects of Oriental herbal medicines on IL-8 induction in lipopolysaccharide-activated rat macrophages
250. Inhibition of inducible nitric oxide synthesis by the herbal preparation Padma 28 in macrophage cell line
251. Inhibitory effect of sesquiterpene lactones from Saussurea lappa on tumor necrosis factor-alpha production in murine macrophage-like cells
252. In vitro anti-inflammatory effects of cynaropicrin, a sesquiterpene lactone, from Saussurea lappa
253. Inhibition of LPS-induced NO production and NF-κB activation by a sesquiterpene from Saussurea lappa
254. Effect of gomisin A (TJN-101) on the arachidonic acid cascade in macrophages
255. Scavenging effects on active oxygen radicals by schizandrins with different structures and configurations
256. Gomisin A inhibits tumor promotion by 12-O-tetradecanoylphorbol-13-acetate in two-stage carcinogenesis in mouse skin
257. Effect of Schizonepeta tenuifolia extract on mast cell-mediated immediate-type hypersensitivity in rats
258. Animal experiments on the allergenicity of d-limonene - The citrus solvent
259. Contact allergy to oxidized d-limonene among dermatitis patients
260. Asthmatic symptoms and volatile organic compounds, formaldehyde, and carbon dioxide in dwellings
261. Inhibitory effect of baicalein, a flavonoid in Scutellaria Root, on eotaxin production by human dermal fibroblasts
262. Pharmacological actions of baicalin and baicalein. 3. Action on experimental asthma
263. Inhibition of hypersensitivity reactions by soluble derivatives of baicalein
264. Anti-inflammatory properties and inhibition of leukotriene C4 biosynthesis in vitro by flavonoid baicalein from Scutellaria baicalensis georgy roots
265. The anti-inflammatory activity of Scutellaria rivularis extracts and its active components, baicalin, baicalein and wogonin
266. Effect of Solanum xanthocarpum and Clerodendron serratum on histamine release from tissues
267. A pilot study on the clinical efficacy of Solanum xanthocarpum and Solanum trilobatum in bronchial asthma
268. Studies on antioxidative activity of some C-glycosylflavones
269. Extract of feverfew inhibits prostaglandin biosynthesis
270. The effect of an aqueous extract of Tanacetum parthenium L. on arachidonic acid metabolism by rat peritoneal leucocytes
271. The anti-inflammatory natural product parthenolide from the medicinal herb feverfew directly binds to and inhibits IκB kinase
272. 5-Hydroxytryptamine-inhibiting property of fever-few: Role of parthenolide content
273. Antispasmodic activity of Thymus vulgaris extract on the isolated guinea-pig trachea: Discrimination between drug and ethanol effects
274. Labiatae allergy: Systemic reactions due to ingestion of oregano and thyme
275. Occupational airborne contact dermatitis caused by thyme dust
276. Trigonella foenum graecum (fenugreek) seed extract as an antineoplastic agent
277. Anti-inflammatory and antipyretic effects of Trigonella foenum-graecum leaves extract in the rat
278. Hypoglycaemic effect of aqueous extract of the leaves of Trigonella foenum-graecum in healthy volunteers
279. Allergy to fenugreek (Trigonella foenum graecum)
280. L-652,469 - A dual receptor antagonist of platelet activating factor and dihydropyridines from Tussilago farfara L
281. A new bisabolene epoxide from Tussilago farfara, and inhibition of nitric oxide synthesis in LPS-activated macrophages
282. Evaluation of tussilagone: A cardiovascular-respiratory stimulant isolated from Chinese herbal medicine
283. Measurement of MEFV in 66 cases of asthma in the convalescent stage and after treatment with Chinese herbs
284. Experimental study on the mode of action of Tylophora asthmatica in bronchial asthma
285. Pharmacological investigations of tylophorine, the major alkaloid of Tylophora indica
286. Effect of tylophorine, a major alkaloid of Tylophora indica, on immunopathological and inflammatory reactions
287. The possible site of anti-asthmatic action of Tylophora asthmatica on pituitary-adrenal axis in albino rats
288. Physical, chemical and biological assay of Tylophora indica mother tincture - A comparative study
289. Immunomodulating agents of plant origin. I: Preliminary screening
290. The possible site of anti-asthmatic action of Tylophora asthmatica on pituitary-adrenal axis in albino rats
291. A crossover double-blind study on Tylophora indica in the treatment of asthma and allergic rhinitis
292. Effect of T. indica on bronchial tolerance to inhalation challenge with specific allergens
293. Treatment of asthma with an alcoholic extract of Tylophora indica: A cross-over, double-blind study
294. Tylophora indica in bronchial asthma (a controlled comparison with a standard antiasthmatic drug)
295. Tylophora indica in bronchial asthma - A double blind study
296. Physiological studies with Tylophora asthmatica in bronchial asthma
297. Antiallergic activity of tylogenin, a novel steroidal compound from Tylophora sylvatica
298. Plant metabolites. New compounds and anti-inflammatory activity of Uncaria tomentosa
299. Antiinflammatory actions of cat's claw: The role of NF-κB
300. Cat's claw inhibits TNFalpha production and scavenges free radicals: Role in cytoprotection
301. Randomized, double-blind study of freeze-dried Urtica dioica in the treatment of allergic rhinitis
302. Ex-vivo in-vitro inhibition of lipopolysaccharide stimulated tumor necrosis factor-alpha and interleukin-1 beta secretion in human whole blood by extractum urticae dioicae foliorum
303. Allergy in the Mediterranean area. II: Cross-allergenicity among Urticaceae pollens (Parietaria and Urtica)
304. Protective antiallergic effects of a new coumarin compound (BM 15.100) in experimental asthma
305. Effect of Ruscus extract and hesperidin methylchalcone on hypoxia-induced activation of endothelial cells
306. The effect of flavonoid treatment on the glycation and antioxidant status in Type 1 diabetic patients
307. Studies on the mast cell stabilising activity of Vitex negundo Linn
308. Inhibition of antigen and compound 48/80 induced contractions of guinea pig trachea by the ethanolic axtract of the leaves of Vitex negundo Linn
309. Phenolic antioxidants from herbs and spices
310. Bioactive saponins and glycosides. X. On the constituents of zizyphi spinosi semen, the seeds of Zizyphus jujuba Mill. var. spinosa Hu (1): Structures and histamine release-inhibitory effect of jujubosides A 1 and C and acetyljujuboside B
311. Effect of the Chinese herbal medicine, Bakumondo-to, on airway hyperresponsiveness induced by ozone exposure in guinea-pigs
312. A pilot phase II study of combination therapy with oxatomide, an antihistamine, plus dextromethoraphan and bakumondo-to, an herbal drug, in patients with postinfectious persistent cough
313. Potentiation of beta-adrenergic function by saiboku-to and bakumondo-to in canine bronchial smooth muscle
314. Effect of DLH-721A and DLH-721B (polyherbal formulations) on rat mesenteric mast cell degranulation
315. Anti-inflammatory effects of mao-bushi-saishin-to in mice and rats
316. I-ephedrine is a major constituent of MaoBushi-Saishin-To, one of the formulas of Chinese medicine, which shows immediate inhibition after oral administration of passive cutaneous anaphylaxis in rats
317. Anti-type I allergic mechanisms of mao-bushisaishin-to in mice
318. Seasonal variations of nasal resistance in allergic rhinitis and environmental pollen counts. II: Efficacy of preseasonal therapy
319. Effects of qing-fei-tang on the airway inflammation and clearance
320. Modulation of human basophil growth in vitro by xiaoqing-long-tang (syo-seiryu-to), chai-pu-tang (saiboku-to), qing-fei-tang (seihai-to), baicalein and ketotifen
321. Effects of qing fei tang (TJ-90) on aspiration pneumonia in mice
322. Effects of ryo-kan-kyomi-sin-ge-ninto extract on degranulation of and histamine release from rat mast cells
323. Effect of Saiboku-to, a blended Chinese traditional medicine, on type I hypersensitivity reactions, particularly on experimentally-caused asthma
324. Effects of an oriental herbal medicine, "Saiboku-to", and its constituent herbs on Compound 48/80-induced histamine release from peritoneal mast cells in rats
325. Inhibitory effects of lignans and flavonoids in saiboku-to, a herbal medicine for bronchial asthma, on the release of leukotrienes from human polymorphonuclear leukocytes
326. Effects of absorbed components of saiboku-to on the release of leukotrienes from polymorphonuclear leukocytes of patients with bronchial asthma
327. Effects of saiboku-to on the survival of human eosinophils
328. Effect of saiboku-to, an antiasthmatic herbal medicine, on nitric oxide generation from cultured canine airway epithelial cells
329. Potentiation of beta-adrenergic function by saiboku-to and bakumondo-to in canine bronchial smooth muscle
330. A strategy for discovering biologically active compounds with high probability in traditional Chinese herb remedies: An application of saiboku-to in bronchial asthma
331. Impact of free magnolol excretions in asthmatic patients who responded well to saiboku-to, a Chinese herbal medicine
332. A novel 11β-hydroxysteroid dehydrogenase inhibitor contained in saiboku-to, a herbal remedy for steroid-dependent bronchial asthma
333. Different effects of traditional Chinese medicines containing similar herbal constituents on prednisolone pharmacokinetics
334. Magnolol inhibits leukotriene synthesis in rat basophilic leukemia-2H3 cells
335. The inhibitory effect of magnolol on cutaneous permeability in mice is probably mediated by a nonselective vascular hyporeactivity to mediators
336. Pharmacological effects of urinary products obtained after treatment with saiboku-to, a herbal medicine for bronchial asthma, on type IV allergic reaction
337. Effects of saiboku-to on dual-phase bronchoconstriction in asthmatic guinea pigs
338. Effect of saiboku-to (TJ-96) on bronchial asthma
339. A multicenter clinical trial of TJ-96 in patients with steroid-dependent bronchial asthma. A comparison of groups allocated by the envelope method
340. Inhibitory effect of Kampo-medicines: Saiboku-to, syouseryu-to, sairei-to on Dermatophagoides farinae antigen-induced IL2 responsiveness in lymphocytes from patients with bronchial asthma and their comparison
341. Effects of the herbal medicine "Sai-rei-to" on in vitro interferon-gamma production of peripheral blood mononuclear cells
342. Saireito (a Chinese herbal drug) decreases inhibitory effect of prednisolone and accelerates the recovery of rat hypothalamic-pituitaryadrenal axis
343. Semi-quantitative analysis of cytokine mRNA expression induced by the herbal medicine Sho-saiko-to (TJ-9) using a Gel Doc system
344. The ex vivo effect of the herbal medicine sho-saiko-to on histamine release from rat mast cells
345. The effect of Chinese herbal medicine, xiao-qing-long tang (XQLT), on allergen-induced bronchial inflammation in mite-sensitized mice
346. Effects of Sho-seiryu-to on experimental allergic rhinitis in guinea pigs
347. 1 receptors and muscarinic cholinergic system in the brain
348. Further pharmacological study on Sho-seiryu-to as an antiallergic
349. An ayurvedic formulation 'Trikatu' and its constituents
350. Anti-allergic effect of an aqueous extract of wu-hu-tang
351. Herbal medicinal products for asthma: A systematic review
352. Natural treatment of perennial allergic rhinitis
353. Studies on the efficacy of unconventional therapies. Problems and designs
354. Serious plant poisonings in Switzerland 1966-1994. Case analysis from the Swiss Toxicology Information Center
355. Herb-drug interactions
356. Surfing the Net - Information on the World Wide Web for persons with arthritis: Patient empowerment or patient deceit?