Inhibition of carcinogenesis by tea

Annual Review of Pharmacology and Toxicology

Volumn 42, Issue , 2002, Pages 25-54

  Yang, Chung S ^a   Maliakal, Pius ^a   Meng, Xiaofeng ^a  

^a RUTGERS UNIVERSITY   (United States)

Author keywords

Cancer; Catechins; Chemoprevention; Dietary

Indexed keywords

ANTIOXIDANT; BLACK TEA EXTRACT; EPICATECHIN; EPICATECHIN GALLATE; EPIGALLOCATECHIN; EPIGALLOCATECHIN GALLATE; POLYPHENOL DERIVATIVE; THEAFLAVIN; THEAFLAVIN 3,3' DIGALLATE;

ANGIOGENESIS; ANTIOXIDANT ACTIVITY; APOPTOSIS; CANCER INHIBITION; CANCER INVASION; CANCER PREVENTION; CELL PROLIFERATION; CELL TRANSFORMATION; CHEMOPROPHYLAXIS; COLON; DOSE RESPONSE; DRUG ACTIVITY; DRUG BIOAVAILABILITY; DRUG MECHANISM; DRUG TRANSFORMATION; ESOPHAGUS; HUMAN; LUNG; MAMMARY GLAND; MOUSE; MOUTH CAVITY; NONHUMAN; PANCREAS; PRIORITY JOURNAL; RAT; REVIEW; SIGNAL TRANSDUCTION; SKIN; SMALL INTESTINE; STOMACH; TEA;

ANGIOGENESIS INHIBITORS; ANIMALS; ANTICARCINOGENIC AGENTS; ANTIOXIDANTS; APOPTOSIS; CATECHIN; CELL CYCLE; FLAVONOIDS; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASES; NEOPLASMS; NF-KAPPA B; PHENOLS; POLYMERS; TEA;

ANIMALIA; CAMELLIA SINENSIS;

EID: 0036169416     PISSN: 03621642     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.pharmtox.42.082101.154309     Document Type: Review

References (118)

1. Tea and cancer: A review
2. Tea and cancer prevention
3. Tea in chemoprevention of cancer: Epidemiologic and experimental stuides
4. Tea and tea polyphenols in cancer prevention
5. Green tea composition, consumption, and polyphenol chemistry
6. The chemistry of tea flavonoids
7. Antioxidants in tea
8. Implications of the mechanisms of action of tea polyphenols as antioxidants in vitro for chemoprevention in humans
9. Scavenging mechanisms of (-)-epigallocatechin gallate and (-)-epicatechin gallate on peroxyl radicals and formation of superoxide during the inhibitory action
10. Antioxidant chemistry of green tea catechins. Identification of products of the reaction of (-)-epigallocatechin gallate with peroxyl radicals
11. Antioxidant chemistry of green tea catechins. New oxidation products of (-)-epigallocatechin gallate and (-)-epigallocatechin from their reactions with peroxyl radicals
12. Comparison of the effects of black and green tea on in vitro lipoprotein oxidation in human serum
13. Inhibition of radical reaction of apolipoprotein B-100 and α-tocopherol in human plasma by green tea catechins
14. Inhibitory effect of tea flavonoids on the ability of cells to oxidize low density lipoprotein
15. Effects of tea consumption on nutrition and health
16. Bioavailability of flavonoids from tea
17. Inhibition of carcinogenesis by tea: Bioavailability of tea polyphenols and mechanisms of actions
18. Accumulation of (-)-epicatechin metabolites in rat plasma after oral administration and distribution of conjugation enzymes in rat tissues
19. Dietary flavonoids as antioxidants in vivo: Conjugated metabolites of (-)-epicatechin and quercetin participate in antioxidative defense in blood plasma
20. Methylation of tea catechins by rat liver homogenates
21. Identification of (-)-epicatechin metabolites and their metabolic fate in the rat
22. O-Methylation of tea polyphenols catalyzed by human placental cytosolic catechol-O-methyltransferase
23. Identification of biliary metabolites of (-)-epigallocatechin gallate in rats
24. 3H]epigallocatechin gallate and its metabolic fate in rats after intravenous administration
25. Epicatechin and catechin are O-methylated and glucuronidated in the small intestine
26. Formation and identification of 4′-O-methyl-(-)-epigallocatechin in humans
27. Catechin metabolites after intake of green tea infusions
28. Structural identification of two metabolites of catechins and their kinetics in human urine and blood after tea ingestion
29. Analysis of urinary metabolites of tea catechins by liquid chromatography/electrospray ionization mass spectrometry
30. Plasma and tissue levels of tea catechins in rats and mice during chronic consumption of green tea polyphenols
31. Absorption, distribution, and elimination of tea polyphenols in rats
32. Absorption and distribution of tea catechin, (-)-epigallocatechin-3-gallate, in the rat
33. 3H](-)-epigallocatechin gallate, a cancer preventive tea polyphenol, in mouse tissue
34. Blood and urine levels of tea catechins after ingestion of different amounts of green tea by human volunteers
35. Phase I pharmacokinetic study of tea polyphenols following single-dose administration of epigallocatechin gallate and polyphenon E
36. Anticarcinogenic effects of (-)-epigallocatechin gallate
37. Prevention of photocarcinogenesis by topical administration of pure epigallocatechin gallate isolated from green tea
38. Protection against induction of mouse skin papillomas with low and high risk of conversion to malignancy by green tea polyphenols
39. Chemopreventive effects of black tea polyphenols in mouse skin model of carcinogenesis
40. Protection by tea against UV-A + B-induced skin cancers in hairless mice
41. Inhibitory effect of black tea on the growth of established skin tumors in mice: Effects on tumor size, apoptosis, mitosis and bromodeoxyuridine incorporation into DNA
42. Effects of tea, decaffeinated tea, and caffeine on UVB light induced complete carcinogenesis in SKH-1 mice: Demonstration of caffeine as a biologically important constituent of tea
43. Effects of oral administration of tea, decaffeinated tea, and caffeine on the formation and growth of tumors in high-risk SKH-1 mice previously treated with ultraviolet B light
44. Inhibitory effects of orally administered green tea, black tea and caffeine on skin carcinogenesis in mice previously treated with UVB (high risk mice): Relationship to decreased tissue fat
45. Characterization of early pulmonary hyperproliferation, tumor progression and their inhibition by black tea in a 4-(methylnitrosamino)-1-(3-pyridyl)-1 butanone (NNK)-induced lung tumorigenesis model with A/J mice
46. Black tea constituents, theaflavins, inhibit 4-(methylnitrosamino)-1-(3-pyridyl)-1 butanone (NNK)-induced lung tumorigenesis in A/J mice
47. Inhibition of spontaneous formation of lung tumors and rhabdomyosarcomas in A/J mice by black and green tea
48. Inhibition of lung carcinogenesis by black tea in Fischer rats treated with a tobaccospecific carcinogen: Caffeine as an important constituent
49. Inhibition of tobacco-specific nitrosamine-induced lung tumorigenesis in A/J mice by green tea and its major polyphenol as antioxidants
50. Inhibitory effect of green tea extract on the carcinogenesis induced by asbestos plus benzo(a)pyrene in rat
51. (-)-Epigallocatechin gallate can prevent cisplatin-induced lung tumorigenesis in A/J mice
52. The effects of phenethyl isothiocyanate. N-acetylcysteine and green tea on tobacco smoke-induced lung tumors in strain A/J mice
53. Tea preparations protect against DMBA-induced oral carcinogenesis in hamsters
54. Effects of theaflavins on N-nitrosomethylbenzylamine-induced esophageal tumorige nesis
55. Inhibition of N-methyl-N′-nitro-N-nitrosoguanidine-induced carcinogenesis by (-)-epigallocatechin gallate in the rat glandular stomach
56. Inhibitory effects and toxicity of green tea polyphenols for gastrointestinal carcinogenesis
57. Combination cancer chemoprevention with green tea extract and sulindac shown in intestinal tumor formation in Min mice
58. Effects of black tea, green tea and wine extracts on intestinal carcinogenesis induced by azoxymethane in F344 rats
59. Effect of tea extracts, polyphenols, and epigallocatechin gallate on azoxymethane-induced colon cancer
60. Effect of black tea on azoxymethane-induced colon cancer
61. Chemoprevention of mammary tumor virus-induced and chemical carcinogen-induced rodent mammary tumors by natural plant products
62. Chemopreventive effects of green and black tea on pulmonary and hepatic carcinogenesis
63. Inhibitory effects of tea catechins, black tea extract and oolong tea extract on hepatocarcinogenesis in rat
64. Inhibitory effects of 1-O-hexyl-2,3,5-trimethylhydroquinone (HTHQ), green tea catechins and other antioxidants on 2-amino-6-methyldipyrido[1,2-a:3′,2′-d]imidazole (Glu-P-1)-induced rat hepatocarcinogenesis and dose-dependent inhibition by HTHQ of lesion induction by Glu-P-1 or 2-amino-3,8-dim ethylimidazo [4,5-f] quinoxaline (MelQx)
65. Phenolics: Blocking agents for heterocyclic amine-induced carcinogenesis
66. Inhibition of urinary bladder tumors induced by N-butyl-N-(4-hydroxybutyl)-nitrosamine in rats by green tea
67. Inhibitory effect of green tea extract on the process of pancreatic carcinogenesis induced by N-nitrosobis-(2-oxypropyl) amine (BOP) and on tumor promotion after transplantation of N-nitrosobis-(2-hydroxypropyl)amine (BHP)-induced pancreatic cancer in Syrian hamsters
68. Inhibitory effects of beta-carotene, palm carotene, and green tea polyphenols on pancreatic carcinogenesis initiated by Nmitorsobis(2-oxopropyl)amine in Syrian golden hamsters
69. Tea, or tea and milk, inhibit mammary gland and colon carcinogenesis in rats
70. Inhibition of mammary gland carcinogenesis by green tea catechins and other naturally occurring antioxidants in female Sprague-Dawley rats pretreated with 7,12,dimethylbenz(a)anthracene
71. Post-initiation inhibitory effects of green tea catechins on 7,12-dimethylbenz[a]anthracene-induced mammary gland carcinogenesis in female Sprague-Dawley rats
72. Effects of green tea catechins on the progression or late promotion stage of mammary gland carcinogenesis in female Sprague-Dawley rats pretreated with 7, 12-dimethylbenz(a)anthracene
73. Black tea and mammary gland carcinogenesis by 7,12-dimethylbenz[a] anthracene in rats fed control or high fat diets
74. Effects of green tea catechins in a rat multiorgan carcinogenesis model
75. Tea as a potential chemopreventive agent in PhIP carcinogenesis: Effects of green tea and black tea on PhIP-DNA adduct formation in female F-344 rats
76. Anti-tumor activity of tea catechins
77. Effect of (-)-epigallocatechin gallate, the main constituent of green tea, on lung metastasis with mouse B16 melanoma cell lines
78. Inhibitory effects of green tea infusion on in vitro invasion and in vivo metastasis of mouse lung carcinoma cells
79. Green tea and its major components ameliorate immune dysfunction in mice bearing Lewis lung carcinoma and treated with the carcinogen NNK
80. Growth inhibition and regression of human prostate and breast tumors in athymic mice by tea epigallocatechin gallate
81. Cancer rates among drinkers of black tea
82. Green tea and cancer in humans: A review of the literature
83. Tea and cancer prevention: An evaluation of the epidemiologic literature
84. Green tea and the risk of gastric cancer in Japan
85. Reduced risk of esophageal cancer associated with green tea consumption
86. Protective effect of green tea on the risks of chronic gastritis and stomach cancer
87. Lead article: Cancer-preventive effects of drinking green tea among a Japanese population
88. Consumption of black tea and cancer risk: A prospective cohort study
89. Growth inhibition of human cancer cell lines by tea polyphenols
90. Inhibition of aberrant proliferation and induction of apoptosis in preneoplastic human mammary epithelial cells by natural phytochemicals
91. Inhibition of tumor promoter-induced AP-1 activation and cell transformation by tea polyphenols, (-)-epigallocatechin gallate and theaflavins
92. Inhibition of activator protein 1 activity and cell growth by purified green tea and black tea polyphenols in H-ras-transformed cells: Structure-activity relationship and mechanisms involved
93. Mechanisms of inhibition of the ras-MAP kinase signaling pathway in 30.7b ras 12 cells by tea polyphenols (-)-epigallocatechin-3-gallate and theaflavin-3,3′-digallate
94. Inhibition of ultraviolet B-induced c-fos gene expression and p38 mitogen-activated protein kinase activation by (-)-epigallocatechin gallate in a human keratinocyte cell line
95. Cancer chemoprevention by tea polyphenols through mitotic signal transduction blockade
96. Green tea polyphenol epigallocatechin-3-gallate differentially modulates nuclear factor kappaB in cancer cells versus normal cells
97. Mechanisms of growth inhibition of human lung cancer cell line, PC-9, by tea polyphenols
98. Green tea constituent epigallocatechin-3-gallate and induction of apoptosis and cell cycle arrest in human carcinoma cells
99. Mechanism of cancer chemopreventive activity of green tea
100. Inhibition of growth and induction of apoptosis in human cancer cell lines by tea polyphenols
101. 2 production in transformed and non-transformed human bronchial cell lines: Possible mechanisms of cell growth inhibition and apoptosis induction
102. Involvement of caspase-3 in epigallocatechin-3-gallate-mediated apoptosis of human chondrosarcoma cells
103. Suppression of lipopolysaccharide-induced nuclear factor-kappa B acctivity by theaflavin-3,3′-digallate from Hacb tea and other polyphenols through down-regulation of lappa B kinose activity in macrophages
104. Inhibition of cyclin-dependent kinases 2 and 4 activities as well as induction of Cdk inhibitors p21 and p27 during growth arrest of human breast carcinoma cells by (-)-epigallocatechin-3-gallate
105. Cell cycle dysregulation by green tea polyphenol epigallocatechin-3-gallate
106. Growth inhibition, cell-cycle dysregulation, and induction of apoptosis by green tea constituent (-)-epigallocatechin-3 -gallate in androgen-sensitive and androgen-insensitive human prostate carcinoma cells
107. Growth factor-dependent induction of p21(CIP1) by the green tea polyphenol, epigallocatechin gallate
108. Suppression of extracellular signals and cell proliferation by the black tea polyphenol, theaflavin-3,3′-digallate
109. Suppression of extracellular signals and cell proliferation through EGF receptor binding by (-)-epigallocatechin gallate in human A431 epidermoid carcinoma cells
110. Green tea compounds inhibit tyrosine phosphorylation of PDGF beta-receptor and transformation of A172 human glioblastoma
111. Tea polyphenols down-regulate the expression of the androgen receptor in LNCaP prostate cancer cells
112. Effects of tea polyphenols on the invasion and matrix metalloproteinases activities of human fibrosarcoma HT1080 cells
113. Matrix metalloproteinase inhibition by green tea catechins
114. Suppression of adhesion and invasion of hepatoma cells in culture by tea compounds through antioxidative activity
115. Angiogenesis inhibited by drinking tea
116. Stimulatory effect of oral administration of green tea or caffeine on UVB-induced increases in epidermal wild-type p53, p21(WAF1/C1P1) and apoptotic sunburn cells in SKH-1 mice
117. Effect of purified green and black tea polypehnols on cyclooxygenase and lipoxygenase-dependent metabolism of arachidonic acid in the human colon mucosa and colon tumor tissues
118. Ingestion of green tea rapidly decreases prostaglandin E2 levels in rectal mucosa in humans