BCR signal through α4 is involved in S6 kinase activation and required for B cell maturation including isotype switching and V region somatic hypermutation

International Immunology

Volumn 14, Issue 2, 2002, Pages 177-187

  Inui, Seiji ^a   Maeda, Kazuhiko ^a   Hua, Ding Rong ^a   Yamashita, Takeshi ^a   Yamamoto, Hideyuki ^a   Miyamoto, Eishichi ^a   Aizawa, Shinichi ^b   Sakaguchi, Nobuo ^a  

^a KUMAMOTO UNIV SCHOOL OF MEDICINE   (Japan)

^b KUMAMOTO UNIVERSITY   (Japan)

Author keywords

Class switch; Gene knockout mouse; Germinal center; S6 kinase; V region somatic hypermutation

Indexed keywords

B LYMPHOCYTE RECEPTOR; BINDING PROTEIN; CD19 ANTIGEN; CD40 ANTIGEN; IMMUNOGLOBULIN CLASS; IMMUNOGLOBULIN M; IMMUNOGLOBULIN RECEPTOR; INTERLEUKIN 4; LIPOPOLYSACCHARIDE; MONOCLONAL ANTIBODY; RAPAMYCIN; S6 KINASE; T LYMPHOCYTE ANTIGEN;

ANIMAL CELL; ANTIBODY RESPONSE; ANTIGEN SPECIFICITY; ARTICLE; B LYMPHOCYTE ACTIVATION; CELL MATURATION; CONTROLLED STUDY; ENZYME ACTIVATION; FEMALE; GERMINAL CENTER; LYMPHOCYTE COUNT; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE PROLIFERATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 0036165407     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/14.2.177     Document Type: Article

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