Mammalian nuclei become licensed for DNA replication during late telophase

Journal of Cell Science

Volumn 115, Issue 1, 2002, Pages 51-59

  Dimitrova, Daniela S ^a   Prokhorova, Tatyana A ^a   Blow, J Julian ^a   Todorov, Ivan T ^a   Gilbert, David M ^a  

^a UNIVERSITY AT BUFFALO   (United States)

Author keywords

Cell cycle; Mammalian nuclei; Mcm proteins; ODP; Replication licensing

Indexed keywords

CELL EXTRACT; DIHYDROFOLATE REDUCTASE; DNA; MINICHROMOSOME MAINTENANCE PROTEIN; PROTEIN INHIBITOR;

ANIMAL CELL; ARTICLE; CELL CYCLE G1 PHASE; CELL NUCLEUS; CELL NUCLEUS MEMBRANE; CELL SYNCHRONIZATION; CHO CELL; CHROMATIN; CONTROLLED STUDY; DNA REPLICATION; DNA REPLICATION ORIGIN; GENE LOCUS; MAMMAL; METAPHASE; NONHUMAN; OOCYTE; PERMEABILITY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEPLETION; TELOPHASE; XENOPUS;

ANIMALS; BLOTTING, WESTERN; CELL CYCLE PROTEINS; CELL EXTRACTS; CELL FRACTIONATION; CELL NUCLEUS; CHO CELLS; CHROMATIN; CRICETINAE; DNA REPLICATION; DNA-BINDING PROTEINS; FEMALE; G1 PHASE; MAMMALS; NUCLEAR PROTEINS; OVUM; REPLICATION ORIGIN; TELOPHASE; TETRAHYDROFOLATE DEHYDROGENASE; XENOPUS;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS; MAMMALIA;

EID: 0036150951     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (47)

1. Genetic dissection of a mammalian replicator in the human β-globin locus
2. Purification of an MCM-containing complex as a component of the DNA replication licensing system
3. Characterization of the Xenopus replication licensing system
4. The Xenopus Cdc6 protein is essential for the initiation of a single round of DNA replication in cell-free extracts
5. Evidence for different MCM subcomplexes with differential binding to chromatin in Xenopus
6. A protein kinase-dependent block to reinitiation of DNA replication in G2 phase in mammalian cells
7. Identification of two residues in MCM5 critical for the assembly of MCM complexes and Stat1-mediated transcription activation in response to IFN-gamma
8. Regulation of mammalian replication origin usage in Xenopus egg extract
9. The spatial position and replication timing of chromosomal domains are both established in early G1 phase
10. Temporally coordinated assembly and disassembly of replication factories in the absence of DNA synthesis
11. Mcm2, but not RPA, is a component of the mammalian early G1-phase prereplication complex
12. Fine mapping of a replication origin of human DNA
13. Site-specific initiation of DNA replication in Xenopus egg extract requires nuclear structure
14. Xenopus lamin B3 has a direct role in the assembly of a replication competent nucleus: Evidence from cell-free egg extracts
15. Regulation of chromosome replication
16. Licensing of DNA replication by a multi-protein complex of MCM/P1 proteins in Xenopus eggs
17. Emerging mechanisms of eukaryotic DNA replication initiation
18. Selective activation of pre-replication complexes in vitro at specific sites in mammalian nuclei
19. Cell cycle regulation of the replication licensing system: Involvement of a Cdk-dependent inhibitor
20. Stepwise regulated chromatin assembly of MCM2-7 proteins
21. XCDT1 is required for the assembly of pre-replicative complexes in Xenopus laevis
22. Geminin, an inhibitor of DNA replication, is degraded during mitosis
23. Chromatin association of human origin recognition complex, cdc6, and minichromosome maintenance proteins during the cell cycle: Assembly of prereplication complexes in late mitosis
24. Methotrexate-resistant Chinese hamster ovary cells have amplified a 135-kilobase-pair region that includes the dihydrofolate reductase gene
25. Selective instability of Orc1 protein accounts for the absence of functional origin recognition complexes during the M-G1 transition in mammals
26. The Cdt1 protein is required to license DNA for replication in fission yeast
27. CDK inactivation is the only essential function of the APC/C and the mitotic exit network proteins for origin resetting during mitosis
28. Association of fission yeast Orp1 and Mcm6 proteins with chromosomal replication origins
29. Sequential MCM/P1 subcomplex assembly is required to form a heterohexamer with replication licensing activity
30. The Xenopus origin recognition complex is essential for DNA replication and MCM binding to chromatin
31. Chromatin proteins involved in the initiation of DNA replication
32. Interaction between the origin recognition complex and the replication licensing system in Xenopus
33. Changes in association of the Xenopus origin recognition complex with chromatin on licensing of replication origins
34. ORC- and Cdc6-dependent complexes at active and inactive chromosomal replication origins in Saccharomyces cerevisiae
35. Repression of origin assembly in metaphase depends on inhibition of RLF-B/Cdt1 by geminin
36. Loading of an Mcm protein onto DNA replication origins is regulated by Cdc6p and CDKs
37. The RLF-M component of the replication licensing system forms complexes containing all six MCM/P1 polypeptides
38. BM28, a human member of the MCM2-3-5 family, is displaced from chromatin during DNA replication
39. MCM proteins in DNA replication
40. Evidence for sequential action of cdc7 and cdk2 protein kinases during initiation of DNA replication in Xenopus egg extracts
41. Inhibition of eukaryotic DNA replication by geminin binding to Cdt1
42. A distinct G1 step required to specify the Chinese hamster DHFR replication origin
43. MCM proteins are associated with RNA polymerase II holoenzyme
44. Biochemical analysis of the intrinsic Mcm4-Mcm6-Mcm7 DNA helicase activity
45. Analysis of mammalian origin specification in ORC-depleted Xenopus egg extracts
46. Ser727-dependent recruitment of MCM5 by Stat1alpha in IFN-gamma-induced transcriptional activation
47. Assembly of a complex containing Cdc45p, replication protein A, and Mcm2p at replication origins controlled by S-phase cyclin-dependent kinases and Cdc7p-Dbf4p kinase