Changes in association of the Xenopus origin recognition complex with chromatin on licensing of replication origins

Journal of Cell Science

Volumn 112, Issue 12, 1999, Pages 2011-2018

  Rowles, Alison ^a,c   Tada, Shusuke ^a,b   Blow, J Julian ^a,b  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

^c GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Cdc6; DNA replication; Licensing factor; ORC; RLF

Indexed keywords

CYCLIN DEPENDENT KINASE; DNA BINDING PROTEIN; SODIUM CHLORIDE;

ARTICLE; CELL FREE SYSTEM; CHROMATIN; CONTROLLED STUDY; DNA REPLICATION; DNA REPLICATION ORIGIN; INTERPHASE; METAPHASE; NONHUMAN; PRIORITY JOURNAL; XENOPUS;

ANIMALS; CELL CYCLE; CELL-FREE SYSTEM; CHROMATIN; CHROMOSOMAL PROTEINS, NON-HISTONE; CYCLIN-DEPENDENT KINASES; DNA REPLICATION; XENOPUS; XENOPUS PROTEINS;

EID: 0032770221     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Bell, S. P. and Stillman, B. (1992). ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex. Nature 357, 128-134.
2. Blow, J. J. and Laskey, R. A. (1986). Initiation of DNA replication in nuclei and purified DNA by a cell-free extract of Xenopus eggs. Cell 47, 577-587.
3. Blow, J. J. and Laskey, R. A. (1988). A role for the nuclear envelope in controlling DNA replication within the cell cycle. Nature 332, 546-548.
4. Blow, J. J. and Nurse, P. (1990). A cdc2-like protein is involved in the initiation of DNA replication in Xenopus egg extracts. Cell 62, 855-862.
5. Blow, J. J. (1993). Preventing re-replication of DNA in a single cell cycle: evidence for a replication licensing factor. J. Cell Biol. 122, 993-1002.
6. Broek, D., Bartlett, R., Crawford, K. and Nurse, P. (1991). Involvement of p34cdc2 in establishing the dependency of S phase on mitosis. Nature 349, 388-393.
7. Burkhart, R., Schulte, D., Hu, D., Musahl, C., Gohring, F. and Knippers, R. (1995). Interactions of human nuclear proteins P1Mcm3 and P1Cdc46. Eur. J. Biochem. 228, 431-438.
8. Chong, J. P. J., Mahbubani, M. H., Khoo, C.-Y. and Blow, J. J. (1995). Purification of an Mcm-containing complex as a component of the DNA replication licensing system. Nature 375, 418-421.
9. Chong, J. P., Thömmes, P., Rowles, A., Mahbubani, H. M. and Blow, J. J. (1997). Characterization of the Xenopus replication licensing system. Meth. Enzymol. 283, 549-564.
10. Coleman, T. R., Carpenter, P. B. and Dunphy, W. G. (1996). The Xenopus Cdc6 protein is essential for the initiation of a single round of DNA replication in cell-free extracts. Cell 87, 53-63.
11. Diffley, J. F. and Cocker, J. H. (1992). Protein-DNA interactions at a yeast replication origin. Nature 357, 169-172.
12. Diffley, J. F., Cocker, J. H., Dowell, S. J. and Rowley, A. (1994). Two steps in the assembly of complexes at yeast replication origins in vivo. Cell 78, 303-316.
13. Diffley, J. F. (1996). Once and only once upon a time: specifying and regulating origins of DNA replication in eukaryotic cells. Genes Dev. 10, 2819-2830.
14. Donovan, S., Harwood, J., Drury, L. S. and Diffley, J. F. (1997). Cdc6p-dependent loading of Mem proteins onto pre-replicative chromatin in budding yeast. Proc. Nat. Acad. Sci. USA 94, 5611-5616.
15. 2-M transitions are controlled by different cdc2 proteins in higher eukaryotes. Cell 66, 731-742.
16. Grallert, B. and Nurse, P. (1996). The ORC1 homolog orp1 in fission yeast plays a key role in regulating onset of S phase. Genes Dev. 10, 2644-2654.
17. Hua, X. H., Yan, H. and Newport, J. (1997). A role for Cdk2 kinase in negatively regulating DNA replication during S phase of the cell cycle. J. Cell Biol. 137, 183-192.
18. Hua, X. H. and Newport, J. (1998). Identification of a preinitiation step in DNA replication that is independent of origin recognition complex and cdc6, but dependent on cdk2. J. Cell Biol. 140, 271-281.
19. Hyrien, O. and Méchali, M. (1993). Chromosomal replication initiates and terminates at random sequences but at regular intervals in the ribosomal DNA of Xenopus early embryos. EMBO J. 12, 4511-4520.
20. CIPI. J. Cell Biol. 130, 755-769.
21. Kubota, Y. and Takisawa, H. (1993). Determination of initiation of DNA replication before and after nuclear formation in Xenopus egg cell free extracts. J. Cell Biol. 123, 1321-1331.
22. Kubota, Y., Mimura, S., Nishimoto, S., Takisawa, H. and Nojima, H. (1995). Identification of the yeast MCM3-related protein as a component of Xenopus DNA replication licensing factor. Cell 81, 601-609.
23. Kubota, Y., Mimura, S., Nishimoto, S., Masuda, T., Nojima, H. and Takisawa, H. (1997). Licensing of DNA replication by a multi-protein complex of MCM/P1 proteins in Xenopus eggs. EMBO J. 16, 3320-3331.
24. Lei, M., Kawasaki, Y. and Tye, B. K. (1996). Physical interactions among Mcm proteins and effects of Mem dosage on DNA replication in Saccharomyces cerevisiae. Mol. Cell Biol. 16, 5081-5090.
25. Liang, C. and Stillman, B. (1997). Persistent initiation of DNA replication and chromatin-bound MCM proteins during the cell cycle in cdc6 mutants. Genes Dev. 11, 3375-3386.
26. Madine, M. A., Khoo, C.-Y., Mills, A. D. and Laskey, R. A. (1995) MCM3 complex required for cell cycle regulation of DNA replication in vertebrate cells. Nature 375, 421-424.
27. Mahbubani, H. M., Paull, T., Elder, J. K. and Blow, J. J. (1992). DNA replication initiates at multiple sites on plasmid DNA in Xenopus egg extracts. Nucl. Acids Res. 20, 1457-1462.
28. Mahbubani, H. M., Chong, J. P., Chevalier, S., Thömmes, P. and Blow, J. J. (1997). Cell cycle regulation of the replication licensing system: involvement of a Cdk-dependent inhibitor. J. Cell Biol. 136, 125-135.
29. Mimura, S. and Takisawa, H. (1998). Xenopus Cdc45-dependent loading of DNA polymerase α onto chromatin under the control of S-phase cdk. EMBO J. 17, 5699-5707.
30. Nishitani, H. and Nurse, P. (1995). p65cdc18 plays a major role controlling the initiation of DNA replication in fission yeast. Cell 83, 397-405.
31. 1 defines a 'point of no return' after which Cdc6 synthesis cannot promote DNA replication in yeast. Genes Dev. 10, 1516-1531.
32. Romanowski, P., Madine, M. A., Rowles, A., Blow, J. J. and Laskey, R. A. (1996). The Xenopus origin recognition complex is essential for DNA replication and MCM binding to chromatin. Curr. Biol. 6, 1416-1425.
33. Rowles, A., Chong, J. P., Brown, L., Howell, M., Evan, G. I. and Blow, J. J. (1996). Interaction between the origin recognition complex and the replication licensing system in Xenopus. Cell 87, 287-296.
34. Saha, P., Chen, J., Kelly, C. T., Lawlis, S. J., Hou, Z.-H., Hendricks, M., Parvin, J. D. and Dutta, A. (1998). Human CDC6/Cdc18 associates with Orc1 and Cyclin-cdk and is selectively eliminated from the nucleus at the onset of S phase. Mol. Cell. Biol. 18, 2758-2767.
35. Strausfeld, U. P., Howell, M., Rempel, R., Maller, J. L., Hunt, T. and Blow, J. J. (1994). Cip1 blocks the initiation of DNA replication in Xenopus extracts by inhibition of cyclin-dependent kinases. Curr. Biol. 4, 876-883.
36. Strausfeld, U. P., Howell, M., Descombes, P., Chevalier, S., Rempel, R. E., Adamczewski, J., Maller, J. L., Hunt, T. and Blow, J. J. (1996). Both cyclin A and cyclin E have S-phase promoting (SPF) activity in Xenopus egg extracts. J. Cell Sci. 109, 1555-1563.
37. Tada, S. and Blow, J. (1998). The replication licensing system. Biol. Chem. 379, 941-949.
38. Tada, S., Chong, J. P. J., Mahbubani, H. M. and Blow, J. J. (1999). The RLF-B component of the replication licensing system is distinct from Cdc6 and functions after Cdc6 binds to chromatin. Curr. Biol. 9, 211-214.
39. Thömmes, P., Kubota, Y., Takisawa, H. and Blow, J. J. (1997). The RLF-M component of the replication licensing system forms complexes containing all six MCM/P1 polypeptides. EMBO J. 16, 3312-3319.
40. Zou, L. and Stillman, B. (1998). Formation of a preinitialion complex by S-phase cyclin CDK-dependent loading of Cdc45p onto chromatin. Science 280, 593-596.