ORC- and Cdc6-dependent complexes at active and inactive chromosomal replication origins in Saccharomyces cerevisiae

EMBO Journal

Volumn 15, Issue 23, 1996, Pages 6671-6679

  Santocanale, Corrado ^a   Diffley, John F X ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

ARS; Genomic footprinting; Origin interference; Origin recognition complex; Replicator

Indexed keywords

CELL CYCLE PROTEIN;

ARTICLE; CHROMATIN; CHROMOSOME REPLICATION; CONTROLLED STUDY; DNA FOOTPRINTING; DNA REPLICATION ORIGIN; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; SACCHAROMYCES CEREVISIAE;

SACCHAROMYCES CEREVISIAE; SACCHAROMYCETALES;

EID: 0029831706     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1996.tb01057.x     Document Type: Article

References (53)

1. Bell, S.P. and Stillman, B. (1992) Nucleotide dependent recognition of chromosomal origins of DNA replication by a multi-protein complex. Nature, 357, 128-134.
2. Bell, S.P., Kobayashi, R. and Stillman, B. (1993) Yeast origin recognition complex functions in transcription silencing and DNA replication. Science, 262, 1844-1849.
3. Bouton, A.H. and Smith, M.M. (1986) Fine-structure analysis of the DNA sequence requirements for autonomous replication of Saccharomyces cerevisiae plasmids. Mol. Cell. Biol., 6, 2354-2363.
4. Brewer, B.J. and Fangman, W.L. (1993) Initiation at closely spaced replication origins in a yeast chromosome. Science, 262, 1728-1731.
5. Brewer, B.J. and Fangman, W.L. (1994) Initiation preference at a yeast origin of replication. Proc. Natl Acad. Sci. USA, 91, 3418-3422.
6. Cocker, J.H., Piatti, S., Santocanale, C, Nasmyth, K. and Diffley, J.F.X. (1996) An essential role for the Cdc6 protein in forming the prereplicative complexes of budding yeast. Nature, 379, 180-182.
7. Crevel, G. and Cotterill, S. (1991) DNA replication in cell-free-extracts from Drosophila melanogaster. EMBO J., 10, 4361-4369.
8. Dahmann, C., Diffley, J.F.X. and Nasmyth, K.A. (1995) S-phase-promoting cyclin-dependent kinases prevent re-replication by inhibiting the transition of origins to a pre-replicative state. Curr. Biol., 5, 1257-1269.
9. Dalton, S. and Whitbread, L. (1995) Cell-cycle-regulated nuclear import and export of Cdc47, a protein essential for initiation of DNA-replication in budding yeast. Proc. Natl Acad. Sco. USA, 92, 2514-2518.
10. DePamphilis, M.L., Martinez-Salas, E., Cupo, D.Y., Hendrickson, E.A., Fritze, C.E., Folk, W.R. and Heine, U. (1988) Initiation of polyomavirus and SV40 DNA replication, and the requirements for DNA replication during mammalian development. In Stillman, B. and Kelly, T. (eds), Eukaryotic DNA Replication. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, Vol. 6, pp. 165-175.
11. Dershowitz, A. and Newlon, C.S. (1993) The effect on chromosome stability of deleting replication origins. Mol Cell. Biol. 13, 391-398.
12. Diffley, J.F.X. (1995) The initiation of DNA replication in the budding yeast cell division cycle. Yeast, 11, 1651-1670.
13. Diffley, J.F.X. and Cocker, J.H. (1992) Protein-DNA interactions at a yeast replication origin. Nature, 357, 169-172.
14. Diffley, J.F.X. and Stillman, B. (1988) Purification of a yeast protein that binds to origins of DNA replication and a transcriptional silencer. Proc. Natl Acad. Sci. USA, 85, 2120-2124.
15. Diffley, J.F.X., Cocker, J.H., Dowell, S.J. and Rowley, A. (1994) Two steps in the assembly of complexes at yeast replication origins in vivo. Cell, 78, 303-316.
16. Dowell, S.J., Romanowski, P. and Diffley, J.F.X. (1994) Interaction of Dbf4, the Cdc7 protein kinase regulatory subunit, with yeast replication origins in vivo. Science, 265, 1243-1246.
17. Dubey, D.D., Davis, L.R., Greenfeder, S.A., Ong, L.Y., Zhu, J.G., Broach, J.R., Newlon, C.S. and Huberman, J.A. (1991) Evidence suggesting that the ARS elements associated with silencers of the yeast mating-type locus HML do not function as chromosomal DNA replication origins. Mol. Cell. Biol., 11, 5346-5355.
18. Fangman, W.L. and Brewer, B.J. (1992) A question of time-replication origins of eukaryotic chromosomes. Cell, 71, 363-366.
19. Foss, M., McNally, F.J., Laurenson, P. and Rine, J. (1993) Origin recognition complex (ORC) in transcriptional silencing and DNA replication in S.cerevisiae. Science, 262, 1838-1844.
20. Fox, C.A., Loo, S., Dillin, A. and Rine, J. (1995) The origin recognition complex has essential functions in transcriptional silencing and chromosomal replication. Genes Dev., 9, 911-924.
21. Greenfeder, S.A. and Newlon, C.S (1992) A replication map of a 61-kb circular derivative of Saccharomyces cerevisiae chromosome III. Mol. Biol. Cell., 3, 999-1013.
22. Harland, R. (1981) Initiation of DNA replication in eukaryotic chromosomes. Trends Biochem. Sci., 6, 71-74.
23. Hartwell, L.H. and Smith, D. (1985) Altered fidelity of mitotic chromosome transmission in cell cycle mutants of S.cerevisiae. Genetics, 110, 381-395.
24. Hennessy, K.M., Clark, C.D. and Botstein, D. (1990) Subcellular localization of yeast CDC46 varies with the cell cycle. Genes Dev., 4, 2252-2263.
25. Hieter, P., Mann, C., Snyder, M. and Davis, R.W. (1985) Mitotic stability of yeast chromosomes: a colony color assay that measures nondisjunction and chromosome loss. Cell. 40, 381-392.
26. Hogan, E. and Koshland, D. (1992) Addition of extra origins of replication to a minichromosome suppresses its mitotic loss in cdc6 and cdc14 mutants of Saccharomyces cerevisiae. Propc. Natl Acad. Sci. USA, 89, 3098-3102.
27. Huberman, J.A. and Riggs, A.D. (1966) Autoradiography of chromosomal DNA fibers from Chinese hamster cells. Proc. Natl Acad. Sci. USA, 55, 599-606.
28. Hyrien, O. and Mechali, M (1992) Plasmid replication in Xenopus eggs and egg extracts - a 2D gel-electrophoretic analysis. Nucleic Acids Res., 20, 1463-1469.
29. Hyrien, O. and Mechali, M. (1993) Chromosomal replication initiates and terminates at random sequences but at regular intervals in the ribosomal DNA of Xenopus early embryos. EMBO J., 12, 4511-4520.
30. Hyrien, O., Maric, C. and Mechali, M. (1995) Transition in specification of embryonic metozoan DNA replication origins. Science, 270, 994-997.
31. Klar, A.J., Strathern, J.N. and Abraham, J.A. (1984) Involvement of double-strand chromosomal breaks for mating-type switching in Saccharomyces cerevisiae. Cold Spring Harbor Symp. Quant. Biol., 49, 77-88.
32. Kostriken, R., Strathern, J.N., Klar, A.J., Hicks, J.B. and Heffron, F. (1983) A site-specific endonuclease essential for mating-type switching in Saccharomyces cerevisiae. Cell, 35, 167-174.
33. Laurenson, P. and Rine, J. (1992) Silencers, silencing and heritable transcriptional states. Microbiol. Rev., 56, 543-560.
34. Liang, C., Weinreich, M. and Stillman, B. (1995) ORC and Cdc6p interact and determine the frequency of initiation of DNA replication in the genome. Cell, 81, 667-676.
35. Loo, S. and Rine, J. (1994) Silencers and domains of generalized repression. Science, 264, 1768-1771.
36. Loo, S., Fox, C.A., Rine, J., Kobayashi, R., Stillman, B. and Bell, S. (1995) The origin recognition complex in silencing, cell-cycle progression, and DNA-replication. Mol. Biol. Cell, 6, 741-756.
37. Mahbubani, H.M., Paull, T., Elder, J.K. and Blow, J.J. (1992) DNA replication initiates at multiple sites on plasmid DNA in Xenopus egg extracts. Nucleic Acids Res., 20, 1457-1462.
38. Marahrens, Y. and Stillman, B. (1992) A yeast chromosomal origin of DNA replication defined by multiple functional elements. Science, 255, 817-823.
39. Marahrens, Y. and Stillman, B. (1994) Replicator dominance in a eukaryotic chromosome, EMBO J., 13, 3395-3400.
40. Martinez Salas, E., Cupo, D.Y. and DePamphilis, M.L. (1988) The need for enhancers is acquired upon formation of a diploid nucleus during early mouse development. Genes Dev., 2, 1115-1126.
41. Mechali, M. and Kearsey, S. (1984) Lack of specific sequence requirement for DNA replication in Xenopus eggs compared with high sequence specificity in yeast. Cell, 38, 55-64.
42. Micklem, G., Rowley, A., Harwood, J., Nasmyth, K. and Diffley, J.F.X. (1993) Yeast origin recognition complex is involved in DNA replication and transcriptional silencing. Nature, 366, 87-89.
43. Newlon, C.S. et al. (1991) Analysis of a circular derivative of Saccharomyces cerevisiae chromosome III: a physical map and identification and location of ARS elements. Genetics, 129, 343-357.
44. Newlon, C.S., Collins, I., Dershowitz, A., Deshpande, A.M., Greenfeder, S.A., Ong, L.Y. and Theis, J.F. (1993) Analysis of replication origin function on chromosome III of Saccharomyces cerevisiae. Cold Spring Harbor Symp. Quant. Biol., 58, 415-423.
45. Palmer, R.E., Hogan, E. and Koshland, D. (1990) Mitotic transmission of artificial chromosomes in cdc mutants of the yeast, Saccharomyces cerevisiae. Genetics, 125, 763-774.
46. Piatti, S., Bohm, T., Cocker, J.H., Diffley, J.F.X. and Nasmyth, K. (1996) Activation of S-phase promoting CDKs in late G1 defines a 'point of no return' after which Cdc6 synthesis cannot promote DNA replication in yeast. Genes Dev., 10, 1516-1531.
47. Rao, H. and Stillman, B (1995) The origin recognition complex interacts with a bipartite DNA binding site within yeast replicators. Proc. Natl Acad. Sci. USA, 92, 2224-2228.
48. Rowley, A., Cocker, J.H., Harwood, J. and Diffley, J.F.X. (1995) Initiation complex assembly at budding yeast replication origins begins with the recognition of a bipartite sequence by limiting amounts of the initiator, ORC. EMBO J., 14, 2631-2641.
49. Schnell, R. and Rine, J. (1986) A position effect on the expression of a tRNA gene mediated by the SIR genes in Sacchammyces cerevisiae. Mol. Cell Biol., 6, 494-501.
50. Sikorski, R.S. and Hieter, P. (1989) A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Sacchammyces cerevisiae. Genetics, 122, 19-27.
51. Strathern, J.N., Klar, A.J., Hicks, J.B., Abraham, J.A., Ivy, J.M., Nasmyth, K.A. and McGill, C. (1982) Homothallic switching of yeast mating type cassettes is initiated by a double-stranded cut in the MAT locus. Cell, 31, 183-192.
52. Sugawara, N., Ivanov, E.L., Fishman Lobell, J., Ray, B.L., Wu, X. and Haber, J.E. (1995) DNA structure-dependent requirements for yeast RAD genes in gene conversion. Nature, 373, 84-86.
53. Yan, H., Merchant, A.M. and Tye, B.-K. (1993) Cell cycle-regulated nuclear localisation of MCM2 and MCM3, which are required for the initiation of DNA synthesis at chromosomal replication origins in yeast. Genes Dev., 7, 2149-2160.