14 The future of genetic case-control studies

Advances in Genetics

Volumn 42, Issue , 2001, Pages 191-212

  Schork, Nicholas J ^a,b,c   Fallin, Dani ^d   Thiel, Bonnie ^a   Xu, Xiping ^b   Broeckel, Ulrich ^e   Jacob, Howard J ^e   Cohen, Daniel ^f  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c JACKSON LABORATORY   (United States)

^d CASE WESTERN RESERVE UNIVERSITY   (United States)

^e MEDICAL COLLEGE OF WISCONSIN   (United States)

^f Genset SA Paris   (France)

Author keywords

[No Author keywords available]

Indexed keywords

MICROSATELLITE DNA;

BIOLOGICAL MODEL; CASE CONTROL STUDY; CHI SQUARE DISTRIBUTION; CLUSTER ANALYSIS; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC HETEROGENEITY; GENETIC LINKAGE; GENETICS; HAPLOTYPE; HUMAN; KIDNEY FAILURE; OUTCOME ASSESSMENT; PHENOTYPE; POPULATION GENETICS; REVIEW; STATISTICAL MODEL;

CASE-CONTROL STUDIES; CHI-SQUARE DISTRIBUTION; CLUSTER ANALYSIS; GENE FREQUENCY; GENETIC HETEROGENEITY; GENETICS, POPULATION; HAPLOTYPES; HUMANS; KIDNEY FAILURE; LINKAGE (GENETICS); LINKAGE DISEQUILIBRIUM; MICROSATELLITE REPEATS; MODELS, GENETIC; MODELS, STATISTICAL; OUTCOME ASSESSMENT (HEALTH CARE); PHENOTYPE;

EID: 0035220161     PISSN: 00652660     EISSN: None     Source Type: Book Series    
DOI: 10.1016/s0065-2660(01)42023-2     Document Type: Review

References (46)

1. A. Arkin J. Ross Statistical construction of chemical reaction mechanisms from measured time-series J. Phys. Chem. 99 1995 970 999
2. A. Arkin P. Shen A test case of correlation metric construction of a reaction pathway from measurements Science 277 1997 1275 1279
3. A.M. Beebe S. Mauze Serial backcross mapping of multiple loci associated with resistance to Leishmania major in mice Immunity 6 1997 551 557
4. N.J. Camp Genomewide transmission/disequilibrium testing: Consideration of the genotype relative risks at disease loci Ame. J. Hum. Gene. 61 1997 1424 1430
5. L.L. Cavalli-Sforza P. Menozzi The History and Geography of Human Genes 1994 Princeton University Press Princeton, NJ
6. A.G. Clark K.M. Weiss Haplotype structure and population-genetics inferences from nucleotide-sequence variation in human lipoprotein lipase Am. J. Hum. Gene. 63 1998 595 612
7. E.S. Collins M.S. Geyer Variations on a theme: Cataloging human DNA sequence variation Science 278 1997 1580 1581
8. E.S. Collins A. Patrinos New goals for the U.S. Human Genome Projects: 1998–2003 Science 282 1998 682 689
9. D. Curtis Genetic dissection of complex traits (letter) Na. Genet. 12 1996 356 358
10. J.L. DeRisi V.R. Iyer Exploring the metabolic and genetic control of gene expression on a genomic scale Science 278 1997 680 686
11. B. Devlin N. Risch A comparison of linkage disequilibrium measures for fine-scale mapping Genomics 29 1995 311 322
12. J.M. Drazen C.N. Yandava Pharmacogenetic association between ALOX5 promoter genotype and the response to anti-asthma treatment Na. Gene. 22 1999 168 170
13. W.J. Ewens R.S. Spielman The transmission/disequilibrium test: History, subdivision, and admixture Am. J. Hum. Gene. 57 1995 455 464
14. L. Excoffier M. Slatkin Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population Mol. Biol. Evol. 12 1995 921 927
15. D. Fallin N.J. Schork The accuracy of haplotype frequency estimation involving biallelic markers and genotypic data 2000 Submitted
16. D. Fallin D. Cohen The power of testing estimated haplotype frequency differences between cases and controls 2000 (In preparation.)
17. E. Feingold P.O. Brown Gaussian models for genetic linkage analysis using complete high resolution maps of identity-by-descent Am. J. Hum. Gene. 53 1993 234 251
18. S. Fields The future is function Na. Gene. 15 1997 325 327
19. P. Good Permutation Tests 1994 Springer-Verlag New York
20. J. Hästbacka A. de la Chapelle Linkage disequilibrium mapping in isolated founder populations: Diastrophic dysplasia in Finland Nat. Gene. 2 1992 204 211
21. M.E. Hawley K.K. Kidd HAPLO: A program using the EM algorithm to estimate the frequencies of multi-site haplotypes J. Hered. 86 1995 409 411
22. L.B. Jorde W.S. Watkins Linkage disequlibrium predicts physical distance in the adenomatous polyposis coli region Am. J. Hum. Gene. 54 1994 884 898
23. M. Laan S. Paabo Demographic history and linkage disequilibrium in human populations Nat. Gene. 17 1997 435 438
24. E.S. Lander The new genomics: Global views of biology Science 274 1996 536 539
25. E. Lander L. Kruglyak Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results Nat. Gene. 11 1995 241 247
26. E.S. Lander N.J. Schork Genetic dissection of complex traits Science 265 1994 2037 2048
27. J.C. Long R.C. Williams An E-M algorithm and testing strategy for multiple locus haplotypes Am. J. Hum. Gene. 56 1995 799 810
28. P.M. McKeigue Mapping genes that underline ethnic differences in disease risk: Methods for detecting linkage in admixed populations, by conditioning on parental admixture Am. J. Hum. Gene. 63 1998 241 251
29. N.E. Morton Significance levels in complex inheritance Am. J. Hum. Gene. 62 1998 690 697
30. J.L. Mountain L.L. Cavalli-Sforza Multilocus genotypes, a tree of individuals, and human evolutionary history Am. J. Hum. Gene. 61 1997 701 715
31. M. Nei Estimation of average heterozygosity and genetic distance from a small number of individuals Genetics 89 1978 583 590
32. J. Neter W. Wasserman Applied Linear Statistical Models 1985 Irwin Homewood, IL
33. J.K. Pritchard N.A. Rosenberg Use of unlinked markers to detect population stratification in association studies Am. J. Hum. Gene. 65 1999 220 228
34. E.G. Puffenberger E.R. Kauffman Identity-by-descent and association mapping of a recessive gene for Hirschprung disease on human chromosome 13q22 Hum. Mot. Gene. 3 1994 1217 1225
35. B. Rannala J.L. Mountain Detecting immigration by using multilocus genotypes Proc. Nail. Acad. Sci. USA 94 1997 9197 9201
36. N. Risch K. Merikangas The future of genetic studies of complex human diseases Science 273 1996 1516 1517
37. D.J. Schaid C. Rowland Use of parents, sibs, and unrelated controls for detection of associations between genetic markers and disease Am. J. Hum. Gene. 63 1988 1492 1506
38. J.J. Schlesselman Case-Control Studies 1982 Oxford University Press New York
39. N.J. Schork D. Fallin Wither association? 2000 (In preparation.)
40. M.D. Shriver M.W. Smith Ethnic affiliation estimation by use of population-specific DNA markers Am. J. Hum. Gene. 60 1997 957 964
41. R.S. Spielman R.E. McGinnis Transmission test for linkage disequilibrium: The insulin gene region and insulin dependent diabetes mellitus (IDDM) Am. J. Hum. Gene. 52 1993 506 516
42. J. Stephens D. Briscoe Mapping by admixture linkage disequilibrium in human populations: Limits and guidelines Am. J. Hum. Genet. 55 1994 809 824
43. J.T. Terwilliger K.M. Weiss Linkage disequilibrium mapping of complex disease: Fantasy of reality? Curr. Opin. Biotechno. 9 1998 578 594
44. S.A. Tishkoff E. Dietzsch Global patterns of linkage disequilibrium at the CD4 locus and modern human origins Science 271 1996 1380 1387
45. D.E. Weeks E. Sobel Computer programs for multilocus haplotyping of general pedigrees Am. J. Hum. Gene. 56 1995 1506 1507
46. J.S. Witte R.C. Elston Genetic dissection of complex traits (letter) Nat. Gene. 12 1996 355 358