Lack of association of 3 functional gene variants with hypertension in African Americans

Hypertension

Volumn 35, Issue 6, 2000, Pages 1297-1300

  Larson, Nicole ^a   Hutchinson, Richard ^b   Boerwinkle, Eric ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

Author keywords

Blacks; Blood pressure; Genes; Hypertension, genetic

Indexed keywords

ADULT; ARTICLE; FEMALE; GENE MUTATION; GENETIC VARIABILITY; GENOME; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; NEGRO; PRIORITY JOURNAL; REGRESSION ANALYSIS;

EID: 0034131317     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.35.6.1297     Document Type: Article

References (23)

1. Kaplan N. Clinical Hypertension. 7th ed. Baltimore, Md: Williams & Wilkins; 1998.
2. Cooper R, Rotimi C. Hypertension in blacks. Am J Hypertens. 1997;10: 804-812.
3. Cope N, Hall H. Risk factors associated with the health status of black women in the United States. In: Jones W, Rice M, editors. Health Care Issues in Black America: Policies, Problems and Prospects. Westport, Conn: Greenwood Press; 1987:44.
4. Kurtz T, Spence M. Genetics of essential hypertension. Am J Med. 1993;94:77-84.
5. Ward R. Familial aggregation and genetic epidemiology of blood pressure. In: Laragh J, Brenner B, eds. Hypertension: Pathophysiology, Diagnosis and Management. New York, NY: Raven Press Ltd; 1995:67-87.
6. Krushkal J, Ferrell R, Mockrin S, Turner S, Sing C, Boerwinkle E. Genome-wide linkage analyses of systolic blood pressure using highly discordant siblings. Circulation. 1999;99:1407-1410.
7. Inoue I, Nakajima T, Williams C, Quackenbush J, Puryear R, Powers M, Cheng T, Ludwig E, Sharma A, Hata A, Jeunemaitre X, Lalouel J. A nucleotide substitution in the promoter of human angiotensinogen is associated with essential hypertension and affects basal transcription in vitro. J Clin Invest. 1997;99:1786-1797.
8. Casari G, Barlassina C, Cusi D, Zagato L, Muirhead R, Righetti M, Nembri P, Amar K, Gatti M, Macciardi F, Binelli G, Bianchi G. Association of the a-adducin locus with essential hypertension. Hypertension. 1995;25:320-326.
9. Siffert W, Rosskopf D, Siffert G, Busch S, Moritz A, Erbel R, Sharma A, Ritz E, Wichmann H, Jakobs K, Horsthemke B. Association of a human G-protein beta3 subunit variant with hypertension. Nat Genet. 1998;18:45-48.
10. 3-subunit gene and lower renin and elevated diastolic blood pressure levels. Hypertension 1998; 32:510-513.
11. Iiri T, Bourne H. G proteins propel surprise. Nat Genet. 1998;18:8-10.
12. ARIC Investigators. The Atherosclerosis Risk in Communities (ARIC) Study: design and objectives. Am J Epidemiol. 1989;129:687-702.
13. Jeunemaitre X, Inoue I, Williams C, Charru A, Tichet J, Powers M, Sharma A, Gimenez-. Roqueplo A, Hata A, Corvol P, Lalouel J. Haplotypes of angiotensinogen in essential hypertension. Am J Hum Genet. 1997;60:1448-1460.
14. Hegele R, Harris S, Hanley A, Sun F, Connelly P, Zinman B. -6A promoter variation of angiotensinogen and blood pressure variation in Canadian Oji-Cree. J Hum Genet. 1998;43:37-41.
15. Manunta P, Barlassina C, Bianchi G. Adducin in essential hypertension. FEBS Lett. 1998;430:41-44.
16. Manunta P, Cusi D, Barlassina C, Righetti M, Lanzani C, D'Amico M, Buzzi L, Citterio L, Stella P, Rivera R, Bianchi G. Alpha-adducin polymorphisms and renal sodium handling in essential hypertensive patients. Kidney Int. 1998;53:1471-1478.
17. Cusi D, Barlassina C, Azzani T, Casari G, Citterio L, Devoto M, Glorioso N, Lanzani C, Manunta P, Righetti M, Rivera R, Stella P, Troffa C, Zagato L, Bianchi G. Polymorphisms of alpha-adducin, and salt sensitivity in patients with essential hypertension. Lancet. 1997;349:1353-1357.
18. Iwai N, Tamaki S, Nakamura Y, Kinoshita M. Polymorphism of a-adducin and hypertension. Lancet. 1997;350:369.
19. Tamaki S, Iwai N, Tsujita Y, Nakamura Y, Kinoshita M. Polymorphism of alpha-adducin in Japanese patients with essential hypertension. Hypertens Res. 1998;21:29-32.
20. Kato N, Sugiyama Y, Nabika T, Morita H, Kurihara H, Yazaki Y, Yamori Y. Lack of association between the a-adducin locus and essential hypertension in the Japanese population. Hypertension. 1998;31:730-733.
21. Ishikawa K, Katsuya T, Sato N, Nakata Y, Takami S, Takiuehi S, Fu Y, Higaki J, Ogihara T. No Association between alpha-adducin 460 polymorphism and essential hypertension in a Japanese population. Am J Hypertens. 1998;11:502-506.
22. 3-subunit gene variant and blood pressure variation in Canadian Oji-Cree. Hypertension. 1998;32:688-692.
23. 3-subunit gene (GNB3) variant in causation of essential hypertension. Hypertension. 1998;32:1094-1097.