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Volumn 29, Issue 1 SUPPL. 4, 2002, Pages 15-26

Overview of rationale and clinical trials with signal transduction inhibitors in lung cancer

Author keywords

[No Author keywords available]

Indexed keywords

4 (3 BROMOANILINO) 6,7 DIMETHOXYQUINAZOLINE; 4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; 6 (4 HYDROXYPHENYL) 4 (ALPHA METHYLBENZYLAMINO) 7H PYRROLO[2,3 D]PYRIMIDINE; CANERTINIB; CELL PROTEIN; ERLOTINIB; GEFITINIB; GUANOSINE TRIPHOSPHATASE; N [4 (3 BROMOANILINO) 6 QUINAZOLINYL]ACRYLAMIDE; PELITINIB; PHOSPHOTYROSINE; PROTEIN TYROSINE KINASE; SU 5259; TRANSCRIPTION FACTOR; TYROSINE KINASE RECEPTOR; UNCLASSIFIED DRUG;

EID: 0036121207     PISSN: 00937754     EISSN: None     Source Type: Journal    
DOI: 10.1053/sonc.2002.31524     Document Type: Article
Times cited : (38)

References (94)
  • 1
    • 0034614490 scopus 로고    scopus 로고
    • Signaling - 2000 and beyond
    • (2000) Cell , vol.100 , pp. 113-127
    • Hunter, T.1
  • 6
    • 0027204266 scopus 로고
    • Transforming growth factor-α, Shope fibroma growth factor, and vaccinia growth factor can replace myxoma growth factor in the induction of myxomatosis in rabbits
    • (1993) Virology , vol.192 , pp. 701-709
    • Opgenorth, A.1    Nation, N.2    Graham, K.3
  • 11
    • 0027159063 scopus 로고
    • Differential expression of the epidermal growth factor receptor and its ligands in primary non-small cell lung cancers and adjacent benign lung
    • (1993) Cancer Res , vol.53 , pp. 2379-2385
    • Rusch, V.1    Baselga, J.2    Cordon-Cardo, C.3
  • 12
    • 0031907022 scopus 로고    scopus 로고
    • Evaluation of epidermal growth factor-related growth factors and receptors and of neoangiogenesis in completely resected stage I-IIIA non-small-cell lung cancer: Amphiregulin and microvessel count are independent prognostic indicators of survival
    • (1998) Clin Cancer Res , vol.4 , pp. 241-249
    • Fontanini, G.1    De Laurentiis, M.2    Vignati, S.3
  • 13
    • 0027232422 scopus 로고
    • The relationship of quantitative epidermal growth factor receptor expression in non-small cell lung cancer to long term survival
    • (1993) Br J Cancer , vol.68 , pp. 162-165
    • Veale, D.1    Kerr, N.2    Gibson, G.J.3
  • 15
  • 16
    • 0031409362 scopus 로고    scopus 로고
    • Epidermal growth factor receptor inhibition by a monoclonal antibody as anticancer therapy
    • (1997) Clin Cancer Res , vol.3 , pp. 2703-2707
    • Mendelsohn, J.1
  • 17
    • 0028116305 scopus 로고
    • Antibody-induced epidermal growth factor receptor dimerization mediates inhibition of autocrine proliferation of A431 squamous carcinoma cells
    • (1994) J Biol Chem , vol.269 , pp. 27595-27602
    • Fan, Z.1    Lu, Y.2    Wu, X.3
  • 19
    • 0031817827 scopus 로고    scopus 로고
    • EGFR blockade by tyrosine kinase inhibitor or monoclonal antibody inhibits growth, directs terminal differentiation, and induces apoptosis in human squamous cell carcinoma HN5
    • (1998) lnt J Oncol , vol.13 , pp. 335-342
    • Modjahedi, H.1    Affleck, K.2    Stubberfield, C.3
  • 22
    • 0023279387 scopus 로고
    • Tumor growth modulation by a monoclonal antibody to the epidermal growth factor receptor: Immunologically mediated and effector cell-independent effects
    • (1987) Cancer Res , vol.47 , pp. 3692-3696
    • Rodeck, U.1    Herlyn, M.2    Herlyn, D.3
  • 23
    • 0026426157 scopus 로고
    • Phase I and imaging trial of indium 111-labeled anti-epidermal growth factor receptor monoclonal antibody 225 in patients with squamous lung carcinoma
    • (1991) J Natl Cancer Inst , vol.83 , pp. 97-104
    • Divgi, C.R.1    Welt, S.2    Kris, M.3
  • 31
    • 0034611617 scopus 로고    scopus 로고
    • Tyrosine kinase inhibitors. 17. Irreversible inhibitors of the epidermal growth factor receptor: 4-(phenylamino)quinazoline and 4-(phenylamino) pyrido
    • (2000) J Med Chem , vol.43 , pp. 1380-1397
    • Smaill, J.B.1    Rewcastle, G.W.2    Loo, J.A.3
  • 36
    • 0031981553 scopus 로고    scopus 로고
    • A potent protein-tyrosine kinase inhibitor which selectively blocks proliferation of epidermal growth factor receptor-expressing tumor cells in vitro and in vivo
    • (1998) Int J Cancer , vol.76 , pp. 154-163
    • Lydon, N.B.1    Mett, H.2    Mueller, M.3
  • 39
    • 0033372557 scopus 로고    scopus 로고
    • Combination of EGFR, HER-2/neu, and HER- 3 is a stronger predictor for the outcome of oral squamous cell carcinoma than any individual family member
    • (1999) Clin Cancer Res , vol.5 , pp. 4164-4174
    • Xia, W.1    Lau, Y.K.2    Zhang, H.Z.3
  • 42
    • 0000240853 scopus 로고    scopus 로고
    • Continuous administration of ZD1839 (Iressa), a novel oral epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), in patients with five selected tumor types: Evidence of activity and good tolerability
    • abstr 686
    • (2000) Proc Am Soc Clin Oncol , vol.19
    • Baselga, J.1    Herbst, R.2    LoRusso, P.3
  • 43
    • 0002200965 scopus 로고    scopus 로고
    • Intermittent oral ZD1839 (Iressa), a novel epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), shows evidence of good tolerability and activity: Final results from a phase I study
    • abstr 5E
    • (2000) Proc Am Soc Clin Oncol , vol.19
    • Ferry, D.1    Hammond, L.2    Ranson, M.3
  • 47
    • 12044258694 scopus 로고
    • Prognostic impact of mutated K-ras gene in surgically resected non-small cell lung cancer patients
    • (1993) Oncogene , vol.8 , pp. 2407-2412
    • Rosell, R.1    Li, S.2    Skacel, Z.3
  • 52
    • 0033214457 scopus 로고    scopus 로고
    • Antitumor efficacy of a novel class of non-thiol-containing peptidomimetic inhibitors of farnesyltransferase and geranylgeranyltransferase I: Combination therapy with the cytotoxic agents cisplatin, Taxol, and gemcitabine
    • (1999) Cancer Res , vol.59 , pp. 4919-4926
    • Sun, J.1    Blaskovich, M.A.2    Knowles, D.3
  • 54
    • 0030952552 scopus 로고    scopus 로고
    • Inhibition of the prenylation of K-Ras, but not H- or N-Ras, is highly resistant to CAAX peptidomimetics and requires both a farnesyltransferase and a geranylgeranyltransferase I inhibitor in human tumor cell lines
    • (1997) Oncogene , vol.15 , pp. 1283-1288
    • Lerner, E.C.1    Zhang, T.T.2    Knowles, D.B.3
  • 55
  • 59
    • 0032546264 scopus 로고    scopus 로고
    • Both farnesyltransferase and geranylgeranyltransferase I inhibitors are required for inhibition of oncogenic K-Ras prenylation but each alone is sufficient to suppress human tumor growth in nude mouse xenografts
    • (1998) Oncogene , vol.16 , pp. 1467-1473
    • Sun, J.1    Qian, Y.2    Hamilton, A.D.3
  • 61
    • 0033546419 scopus 로고    scopus 로고
    • Four human ras homologs differ in their abilities to activate Raf-1, induce transformation, and stimulate cell motility
    • (1999) J Biol Chem , vol.274 , pp. 17164-17170
    • Voice, J.K.1    Klemke, R.L.2    Le, A.3
  • 67
    • 0033860183 scopus 로고    scopus 로고
    • RhoB alteration is necessary for apoptotic and antineoplastic responses to farnesyltransferase inhibitors
    • (2000) Mol Cell Biol , vol.20 , pp. 6105-6113
    • Liu, A.X.1    Du, W.2    Liu, J.P.3
  • 70
    • 0034674417 scopus 로고    scopus 로고
    • Both farnesylated and geranylgeranylated RhoB inhibit malignant transformation and suppress human tumor growth in nude mice
    • (2000) J Biol Chem , vol.275 , pp. 17974-17978
    • Chen, Z.1    Sun, J.2    Pradines, A.3
  • 73
    • 14344254868 scopus 로고    scopus 로고
    • Antitumor activity of SCH66336, an orally bioavailable tricyclic inhibitor of farnesyl protein transferase, in human tumor xenograft models and Wap-ras transgenic mice
    • (1998) Cancer Res , vol.58 , pp. 4947-4956
    • Liu, M.1    Bryant, M.S.2    Chen, J.3
  • 81
  • 82
    • 0027418615 scopus 로고
    • Recombinant human stem cell factor mediates chemotaxis of small-cell lung cancer cell lines aberrantly expressing the c-kit protooncogene
    • (1993) Cancer Res , vol.53 , pp. 1709-1714
    • Sekido, Y.1    Takahashi, T.2    Ueda, R.3
  • 84
    • 0028020385 scopus 로고
    • Lysophosphatidic acid-depleted serum, hepatocyte growth factor, and stem cell growth factor stimulate colony growth of small cell lung cancer cells through a calcium-independent pathway
    • (1994) Cancer Res , vol.54 , pp. 6143-6147
    • Seckl, M.J.1    Seufferlein, T.2    Rozengurt, E.3
  • 88
    • 0031454003 scopus 로고    scopus 로고
    • CGP 57148, a tyrosine kinase inhibitor, inhibits the growth of cells expressing BCR-ABL, TEL-ABL, and TEL-PDGFR fusion proteins
    • (1997) Blood , vol.90 , pp. 4947-4952
    • Carroll, M.1    Ohno-Jones, S.2    Tamura, S.3
  • 90
    • 15444350807 scopus 로고    scopus 로고
    • Selective inhibition of cell proliferation and BCR-ABL phosphorylation in acute lymphoblastic leukemia cells expressing Mr 190,000 BCK-ABL protein by a tyrosine kinase inhibitor (CGP-57148)
    • (1998) Clin Cancer Res , vol.4 , pp. 1661-1672
    • Beran, M.1    Cao, X.2    Estrov, Z.3
  • 91


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.