Unliganded epidermal growth factor receptor dimerization induced by direct interaction of quinazolines with the ATP binding site

Journal of Biological Chemistry

Volumn 272, Issue 37, 1997, Pages 23247-23254

  Arteaga, Carlos L ^a,b,f   Ramsey, Timothy T ^c   Shawver, Laura K ^d   Guyer, Cheryl A ^e  

^a VANDERBILT INGRAM CANCER CENTER   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^d SUGEN INC   (United States)

^e VANDERBILT UNIVERSITY   (United States)

^f VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; EPIDERMAL GROWTH FACTOR RECEPTOR; PROTEIN TYROSINE KINASE; QUINAZOLINE DERIVATIVE;

ARTICLE; BINDING SITE; DIMERIZATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DOMAIN; RECEPTOR BINDING; SIGNAL TRANSDUCTION;

ADENOSINE; ADENOSINE TRIPHOSPHATE; ADENYLYL IMIDODIPHOSPHATE; BINDING SITES; CARRIER PROTEINS; DIMERIZATION; ENZYME INHIBITORS; GLYCOPROTEINS; HUMANS; LIGANDS; NEUREGULIN-1; NITRILES; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN CONFORMATION; QUINAZOLINES; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, ERBB-2; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED; TYRPHOSTINS;

EID: 0030801361     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.37.23247     Document Type: Article

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