Patented small molecule inhibitors of HIV-1 integrase: A 10-year saga

Expert Opinion on Therapeutic Patents

Volumn 12, Issue 5, 2002, Pages 709-724

  Neamati, Nouri ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Diketoacids; Drug discovery; HIV 1 integrase; Inhibitor design; Natural products; S 1360

Indexed keywords

1 [5 (4 FLUOROBENZYL) 2 FURYL] 3 (1,2,4 TRIAZOL 3 YL) 1,3 PROPANEDIONE; ANTIBODY; ANTIRETROVIRUS AGENT; BIS(AMIDINOBENZIMIDAZOLE) DERIVATIVE; BIS(AMINOBENZIMIDAZOLYL)ALKANE DERIVATIVE; CHICORIC ACID DERIVATIVE; CURCUMIN DERIVATIVE; DIKETOACID DERIVATIVE; DIOXOHEX 2 ENOIC ACID DERIVATIVE; INDOLOQUINOXALINE; INTEGRASE; INTEGRASE INHIBITOR; LAMIVUDINE; LEXITROPSIN DERIVATIVE; MERCAPTOSALICYLHYDRAZIDE DERIVATIVE; NATURAL PRODUCT; NELFINAVIR; NEVIRAPINE; OLIGONUCLEOTIDE; PENTAMIDINE DERIVATIVE; POLYPEPTIDE; SALICYLHYDRAZIDE DERIVATIVE; SESQUITERPENOID DERIVATIVE; TETRACYCLIC AROMATIC KETONE DERIVATIVE; THIAZEPINE DERIVATIVE; THIAZOLOTHIAZEPINE DERIVATIVE; TOMACRAZINE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VIRUS ENZYME; ZIDOVUDINE;

ANTIVIRAL ACTIVITY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG DESIGN; DRUG EFFICACY; DRUG POTENTIATION; DRUG STRUCTURE; DRUG TARGETING; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; NONHUMAN; PATENT; REVIEW; VIRUS INHIBITION;

EID: 0036107683     PISSN: 13543776     EISSN: None     Source Type: Journal    
DOI: 10.1517/13543776.12.5.709     Document Type: Review

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