-
1
-
-
0029055551
-
Isolation of high-affinity RNA ligands to HIV1 integrase from a random pool
-
Allen P, Worland S & Gold L (1995) Isolation of high-affinity RNA ligands to HIV1 integrase from a random pool. Virology 209: 327-336.
-
(1995)
Virology
, vol.209
, pp. 327-336
-
-
Allen, P.1
Worland, S.2
Gold, L.3
-
2
-
-
0028863151
-
Multimerization determinants reside in both the catalytic core and C terminus of avian sarcoma virus integrase
-
Andrake MD & Skalka AM (1995) Multimerization determinants reside in both the catalytic core and C terminus of avian sarcoma virus integrase. Journal of Biological Chemistry 270: 29299-23006.
-
(1995)
Journal of Biological Chemistry
, vol.270
, pp. 29299-123006
-
-
Andrake, M.D.1
Skalka, A.M.2
-
4
-
-
0030922072
-
A metal-induced conformational change and activation of HIV-1 integrase
-
Asante-Appiah E & Skalka AM (1997) A metal-induced conformational change and activation of HIV-1 integrase. Journal of Biological Chemistry 272: 16196-16205.
-
(1997)
Journal of Biological Chemistry
, vol.272
, pp. 16196-16205
-
-
Asante-Appiah, E.1
Skalka, A.M.2
-
5
-
-
0031028292
-
Functional identification of nucleotides conferring substrate specificity to retroviral integrase reactions
-
Balakrishnan M & Jonsson CB (1997) Functional identification of nucleotides conferring substrate specificity to retroviral integrase reactions. Journal of Virology 71: 1025-1035.
-
(1997)
Journal of Virology
, vol.71
, pp. 1025-1035
-
-
Balakrishnan, M.1
Jonsson, C.B.2
-
6
-
-
0030003130
-
Inhibition of human immunodeficiency virus type 1 integrase by the Fab fragment of a specific monoclonal antibody suggests that different multimerization states are required for different enzymatic functions
-
Barsov EV, Huber WE, Marcotrigiano J, Clark PK, Clark AD, Arnold E & Hughes SH (1996) Inhibition of human immunodeficiency virus type 1 integrase by the Fab fragment of a specific monoclonal antibody suggests that different multimerization states are required for different enzymatic functions. Journal of Virology 70: 4484-4494.
-
(1996)
Journal of Virology
, vol.70
, pp. 4484-4494
-
-
Barsov, E.V.1
Huber, W.E.2
Marcotrigiano, J.3
Clark, P.K.4
Clark, A.D.5
Arnold, E.6
Hughes, S.H.7
-
7
-
-
0027231782
-
Structure of DNA polymerase I Klenow fragment bound to duplex DNA
-
Beese LS, Derbyshire V & Steitz TA (1993) Structure of DNA polymerase I Klenow fragment bound to duplex DNA. Science 260: 352-355.
-
(1993)
Science
, vol.260
, pp. 352-355
-
-
Beese, L.S.1
Derbyshire, V.2
Steitz, T.A.3
-
8
-
-
0026590931
-
HIV-1 integrase: High-level production and screening assay for the endonucleolytic activity
-
Billich A, Schauer M, Frank S, Rosenwirth B & Billich S (1992) HIV-1 integrase: high-level production and screening assay for the endonucleolytic activity. Antiviral Chemistry and Chemotherapy 3: 113-119.
-
(1992)
Antiviral Chemistry and Chemotherapy
, vol.3
, pp. 113-119
-
-
Billich, A.1
Schauer, M.2
Frank, S.3
Rosenwirth, B.4
Billich, S.5
-
10
-
-
0030219760
-
Target-sequence preferences of HIV-1 integration complexes in vitro
-
Bor YC, Miller MD, Bushman FD & Orgel LE (1996) Target-sequence preferences of HIV-1 integration complexes in vitro. Virology 222: 283-288.
-
(1996)
Virology
, vol.222
, pp. 283-288
-
-
Bor, Y.C.1
Miller, M.D.2
Bushman, F.D.3
Orgel, L.E.4
-
11
-
-
0029008475
-
Impairment of Moloney murine leukemia virus integration in a cell line underexpressing DNA topoisomerase II
-
Bouillé P, Subra F, Goulaouic H, Carteau S & Auclair C (1995) Impairment of Moloney murine leukemia virus integration in a cell line underexpressing DNA topoisomerase II. Cancer Research 55: 3211-3217.
-
(1995)
Cancer Research
, vol.55
, pp. 3211-3217
-
-
Bouillé, P.1
Subra, F.2
Goulaouic, H.3
Carteau, S.4
Auclair, C.5
-
12
-
-
0029990185
-
Alternate strand DNA triple helix-mediated inhibition of HIV-1 U5 long terminal repeat integration in vitro
-
Bouziane M, Cherny DI, Mouscadet J-F & Auclair C (1996) Alternate strand DNA triple helix-mediated inhibition of HIV-1 U5 long terminal repeat integration in vitro. Journal of Biological Chemistry 271: 10359-10364.
-
(1996)
Journal of Biological Chemistry
, vol.271
, pp. 10359-10364
-
-
Bouziane, M.1
Cherny, D.I.2
Mouscadet, J.-F.3
Auclair, C.4
-
15
-
-
0030566832
-
The catalytic domain of human immunodeficiency virus integrase: Ordered active site in the F185H mutant
-
Bujacz G, Alexandratos J, Qing ZL, Clement-Mella C & Wlodawer A (1996a) The catalytic domain of human immunodeficiency virus integrase: ordered active site in the F185H mutant. FEBS Letters 398: 175-178.
-
(1996)
FEBS Letters
, vol.398
, pp. 175-178
-
-
Bujacz, G.1
Alexandratos, J.2
Qing, Z.L.3
Clement-Mella, C.4
Wlodawer, A.5
-
16
-
-
0029643858
-
The catalytic domain of avian sarcoma virus integrase: Conformation of the active-site residues in the presence of divalent cations
-
Bujacz G, Jaskolski M, Alexandratos J, Wlodawer A, Merkel G, Katz RA & Skalka AM (1996b) The catalytic domain of avian sarcoma virus integrase: conformation of the active-site residues in the presence of divalent cations. Current Biology 4: 89-96.
-
(1996)
Current Biology
, vol.4
, pp. 89-96
-
-
Bujacz, G.1
Jaskolski, M.2
Alexandratos, J.3
Wlodawer, A.4
Merkel, G.5
Katz, R.A.6
Skalka, A.M.7
-
17
-
-
0030746054
-
Binding of different divalent cations to the active site of avian sarcoma virus integrase and their effects on enzymatic activity
-
in press
-
Bujacz G, Alexandratos J, Wlodawer A, Merkel G, Andrake M, Katz RA & Skalka AM (1997) Binding of different divalent cations to the active site of avian sarcoma virus integrase and their effects on enzymatic activity. Journal of Biological Chemistry (in press).
-
(1997)
Journal of Biological Chemistry
-
-
Bujacz, G.1
Alexandratos, J.2
Wlodawer, A.3
Merkel, G.4
Andrake, M.5
Katz, R.A.6
Skalka, A.M.7
-
18
-
-
0030031403
-
Phosphorylation-dependent human immunodeficiency virus type 1 infection and nuclear targeting of viral DNA
-
Bukrinskaya AG, Ghorpade A, Heinzinger NK, Smithgall TE, Lewis RE & Stevenson M (1996) Phosphorylation-dependent human immunodeficiency virus type 1 infection and nuclear targeting of viral DNA. Proceedings of the National Academy of Sciences, USA 93: 367-371.
-
(1996)
Proceedings of the National Academy of Sciences, USA
, vol.93
, pp. 367-371
-
-
Bukrinskaya, A.G.1
Ghorpade, A.2
Heinzinger, N.K.3
Smithgall, T.E.4
Lewis, R.E.5
Stevenson, M.6
-
19
-
-
0026770379
-
Active nuclear import of human immunodeficiency virus type 1 preintegration complexes
-
Bukrinsky MI, Sharova N, Dempsey MP, Stanwick TL, Bukrinskaya AG, Haggerty S & Stevenson M (1992) Active nuclear import of human immunodeficiency virus type 1 preintegration complexes. Proceedings of the National Academy of Sciences, USA 89: 6580-6584.
-
(1992)
Proceedings of the National Academy of Sciences, USA
, vol.89
, pp. 6580-6584
-
-
Bukrinsky, M.I.1
Sharova, N.2
Dempsey, M.P.3
Stanwick, T.L.4
Bukrinskaya, A.G.5
Haggerty, S.6
Stevenson, M.7
-
20
-
-
0027199982
-
Association of integrase, matrix, and reverse transcriptase antigens of human immunodeficiency virus type 1 with viral nucleic acids following acute infection
-
Bukrinsky MI, Sharova N, McDonald TL, Pushkarskaya T, Tarpley WG & Stevenson M (1993a) Association of integrase, matrix, and reverse transcriptase antigens of human immunodeficiency virus type 1 with viral nucleic acids following acute infection. Proceedings of the National Academy of Sciences, USA 90: 6125-6129.
-
(1993)
Proceedings of the National Academy of Sciences, USA
, vol.90
, pp. 6125-6129
-
-
Bukrinsky, M.I.1
Sharova, N.2
McDonald, T.L.3
Pushkarskaya, T.4
Tarpley, W.G.5
Stevenson, M.6
-
21
-
-
0027376309
-
A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells
-
Bukrinsky MI, Haggerty S, Dempsey MP, Sharova N, Adzhubel A, Spitz L, Lewis P, Goldfarb D, Emerman M & Stevenson M (1993b) A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells. Nature 365: 666-669.
-
(1993)
Nature
, vol.365
, pp. 666-669
-
-
Bukrinsky, M.I.1
Haggerty, S.2
Dempsey, M.P.3
Sharova, N.4
Adzhubel, A.5
Spitz, L.6
Lewis, P.7
Goldfarb, D.8
Emerman, M.9
Stevenson, M.10
-
22
-
-
0026655897
-
Structural implications of spectroscopic characterization of a putative zinc finger peptide from HIV-1 integrase
-
Burke CJ, Sanyal G, Bruner MW, Ryan JA, LaFemina RL, Robbins HL, Zeft AS, Russell Middaugh C & Cordingley MG (1992) Structural implications of spectroscopic characterization of a putative zinc finger peptide from HIV-1 integrase. Journal of Biological Chemistry 267: 9639-9644.
-
(1992)
Journal of Biological Chemistry
, vol.267
, pp. 9639-9644
-
-
Burke, C.J.1
Sanyal, G.2
Bruner, M.W.3
Ryan, J.A.4
LaFemina, R.L.5
Robbins, H.L.6
Zeft, A.S.7
Russell Middaugh, C.8
Cordingley, M.G.9
-
23
-
-
0028824133
-
Hydroxylated aromatic inhibitors of HIV-1 integrase
-
Burke TR, Fesen M, Mazumder A, YungJ, Wang J, Carothers AM, Grunberger D, Driscoll J & Pommier Y (1995) Hydroxylated aromatic inhibitors of HIV-1 integrase. Journal of Medicinal Chemistry 38: 4171-4178.
-
(1995)
Journal of Medicinal Chemistry
, vol.38
, pp. 4171-4178
-
-
Burke, T.R.1
Fesen, M.2
Mazumder, A.3
Yung, J.4
Wang, J.5
Carothers, A.M.6
Grunberger, D.7
Driscoll, J.8
Pommier, Y.9
-
24
-
-
0026034790
-
Activities of human immunodeficiency virus (HIV) integration protein in vitro: Specific cleavage and integration of HIV DNA
-
Bushman FD & Craigie R (1991) Activities of human immunodeficiency virus (HIV) integration protein in vitro: specific cleavage and integration of HIV DNA. Proceedings of the National Academy of Sciences, USA 88: 1339-1343.
-
(1991)
Proceedings of the National Academy of Sciences, USA
, vol.88
, pp. 1339-1343
-
-
Bushman, F.D.1
Craigie, R.2
-
25
-
-
0026568640
-
Integration of human immunodeficiency virus DNA: Adduct interference analysis of required DNA sites
-
Bushman FD & Craigie R (1992) Integration of human immunodeficiency virus DNA: adduct interference analysis of required DNA sites. Proceedings of the National Academy of Sciences, USA 89: 3458-3462.
-
(1992)
Proceedings of the National Academy of Sciences, USA
, vol.89
, pp. 3458-3462
-
-
Bushman, F.D.1
Craigie, R.2
-
26
-
-
0025133394
-
Retroviral DNA integration directed by HIV integration protein in vitro
-
Bushman FD, Fujiwara T & Craigie R (1990) Retroviral DNA integration directed by HIV integration protein in vitro. Science 249: 1555-1558.
-
(1990)
Science
, vol.249
, pp. 1555-1558
-
-
Bushman, F.D.1
Fujiwara, T.2
Craigie, R.3
-
27
-
-
0027456715
-
Domains of the integrase protein of human immunodeficiency virus type 1 responsible for polynucleotidyl transfer and zinc binding
-
Bushman FD, Engelman A, Palmer I, Wingfield P & Craigie R (1993) Domains of the integrase protein of human immunodeficiency virus type 1 responsible for polynucleotidyl transfer and zinc binding. Proceedings of the National Academy of Sciences, USA 90: 3428-3432.
-
(1993)
Proceedings of the National Academy of Sciences, USA
, vol.90
, pp. 3428-3432
-
-
Bushman, F.D.1
Engelman, A.2
Palmer, I.3
Wingfield, P.4
Craigie, R.5
-
28
-
-
0028225959
-
Human immunodeficiency virus type 1 integrase: Effect on viral replication of mutation at highly conserved residues
-
Cannon PM, Wilson W, Byles E, Kingsman SM & Kingsman AJK (1994) Human immunodeficiency virus type 1 integrase: effect on viral replication of mutation at highly conserved residues. Journal of Virology 68: 4768-4775.
-
(1994)
Journal of Virology
, vol.68
, pp. 4768-4775
-
-
Cannon, P.M.1
Wilson, W.2
Byles, E.3
Kingsman, S.M.4
Kingsman, A.J.K.5
-
29
-
-
0029655459
-
Conserved sequences in the carboxyl terminus of integrase that are essential for human immunodeficiency virus type 1 replication
-
Cannon PM, Byles ED, Kingsman SM & Kingsman AJ (1996) Conserved sequences in the carboxyl terminus of integrase that are essential for human immunodeficiency virus type 1 replication. Journal of Virology 70: 651-657.
-
(1996)
Journal of Virology
, vol.70
, pp. 651-657
-
-
Cannon, P.M.1
Byles, E.D.2
Kingsman, S.M.3
Kingsman, A.J.4
-
30
-
-
0027227754
-
Effect of topoisomerase inhibitors on the in vitro HIV DNA integration reaction
-
Carteau S, Mouscadet J-F, Goulaouic H, Subra F & Auclair C (1993a) Effect of topoisomerase inhibitors on the in vitro HIV DNA integration reaction. Biochemical and Biophysical Research Communications 192: 1409-1414.
-
(1993)
Biochemical and Biophysical Research Communications
, vol.192
, pp. 1409-1414
-
-
Carteau, S.1
Mouscadet, J.-F.2
Goulaouic, H.3
Subra, F.4
Auclair, C.5
-
31
-
-
0027222149
-
Inhibitory effect of the polyanionic drug suramin on the in vitro HIV DNA integration reaction
-
Carteau S, Mouscadet J-F, Goulaouic H, Subra F & Auclair C (1993b) Inhibitory effect of the polyanionic drug suramin on the in vitro HIV DNA integration reaction. Archives of Biochemistry and Biophysics 305: 606-610.
-
(1993)
Archives of Biochemistry and Biophysics
, vol.305
, pp. 606-610
-
-
Carteau, S.1
Mouscadet, J.-F.2
Goulaouic, H.3
Subra, F.4
Auclair, C.5
-
32
-
-
0028303604
-
Inhibition of the in vitro integration of Moloney murine leukemia virus DNA by the DNA minor groove binder netropsin
-
Carteau S, Mouscadet JF, Goulaouic H, Subra F & Auclair C (1994) Inhibition of the in vitro integration of Moloney murine leukemia virus DNA by the DNA minor groove binder netropsin. Biochemical Pharmacology 47: 1821-1826.
-
(1994)
Biochemical Pharmacology
, vol.47
, pp. 1821-1826
-
-
Carteau, S.1
Mouscadet, J.F.2
Goulaouic, H.3
Subra, F.4
Auclair, C.5
-
34
-
-
0027971617
-
Juxtaposition of two viral DNa ends in a bimolecular disintegration reaction mediated by multimers of human immunodeficiency virus type 1 or murine leukemia virus integrase
-
Chow SA & Brown PO (1994) Juxtaposition of two viral DNA ends in a bimolecular disintegration reaction mediated by multimers of human immunodeficiency virus type 1 or murine leukemia virus integrase. Journal of Virology 68: 7869-7878.
-
(1994)
Journal of Virology
, vol.68
, pp. 7869-7878
-
-
Chow, S.A.1
Brown, P.O.2
-
35
-
-
0026549933
-
Reversal of integration and DNA splicing mediated by integrase of human immunodeficiency virus
-
Chow SA, Vincent KA, Ellison V & Brown PO (1992) Reversal of integration and DNA splicing mediated by integrase of human immunodeficiency virus. Science 255: 723-726.
-
(1992)
Science
, vol.255
, pp. 723-726
-
-
Chow, S.A.1
Vincent, K.A.2
Ellison, V.3
Brown, P.O.4
-
37
-
-
0026659014
-
Inhibition of HIV-1 integration protein by aurintricarboxylic acid monomers, monomer analogs, and polymer fractions
-
Cushman M & Sherman P (1992) Inhibition of HIV-1 integration protein by aurintricarboxylic acid monomers, monomer analogs, and polymer fractions. Biochemical and Biophysical Research Communications 185: 85-90.
-
(1992)
Biochemical and Biophysical Research Communications
, vol.185
, pp. 85-90
-
-
Cushman, M.1
Sherman, P.2
-
38
-
-
0029065930
-
Cosalane analogues with enhanced potencies as inhibitors of HIV-1 protease and integrase
-
Cushman M, Golebiewski WM, Pommier Y, Mazumder A, Reymen D, De Clercq E, Graham L & Rice WG (1995) Cosalane analogues with enhanced potencies as inhibitors of HIV-1 protease and integrase. Journal of Medicinal Chemistry 38: 443-452.
-
(1995)
Journal of Medicinal Chemistry
, vol.38
, pp. 443-452
-
-
Cushman, M.1
Golebiewski, W.M.2
Pommier, Y.3
Mazumder, A.4
Reymen, D.5
De Clercq, E.6
Graham, L.7
Rice, W.G.8
-
40
-
-
0027489647
-
Influence of substrate structure on disintegration activity of Moloney murine leukemia virus integrase
-
Donzella GA, Jonsson CB & Roth MJ (1993) Influence of substrate structure on disintegration activity of Moloney murine leukemia virus integrase. Journal of Virology 67: 7077-7087.
-
(1993)
Journal of Virology
, vol.67
, pp. 7077-7087
-
-
Donzella, G.A.1
Jonsson, C.B.2
Roth, M.J.3
-
41
-
-
0006430045
-
Identification of the antiviral nucleoside drug binding site of HIV-1 integrase by proteolytic peptide mapping
-
Drake R, Neamati N, Sunthankar P, Mazumder A & Pommier Y (1997) Identification of the antiviral nucleoside drug binding site of HIV-1 integrase by proteolytic peptide mapping. Antiviral Research 34: A42.
-
(1997)
Antiviral Research
, vol.34
-
-
Drake, R.1
Neamati, N.2
Sunthankar, P.3
Mazumder, A.4
Pommier, Y.5
-
42
-
-
0026740842
-
Identification of amino acid residues critical for endonuclease and integration activities of HIV-1 protein in vitro
-
Drelich M, Wilhelm R & Mous J (1992) Identification of amino acid residues critical for endonuclease and integration activities of HIV-1 protein in vitro. Virology 188: 459-468.
-
(1992)
Virology
, vol.188
, pp. 459-468
-
-
Drelich, M.1
Wilhelm, R.2
Mous, J.3
-
43
-
-
0028584269
-
Crystal structure of the catalytic domain of HIV-1 integrase: Similarity of other polynucleotide transferases
-
Dyda F, Hickman AB, Jenkins TM, Engelman A, Craigie R & Davies DR (1994) Crystal structure of the catalytic domain of HIV-1 integrase: similarity of other polynucleotide transferases. Science 266: 1981-1986.
-
(1994)
Science
, vol.266
, pp. 1981-1986
-
-
Dyda, F.1
Hickman, A.B.2
Jenkins, T.M.3
Engelman, A.4
Craigie, R.5
Davies, D.R.6
-
44
-
-
0030041593
-
(-)-Arctigenin as a lead structure for inhibitors of human immunodeficiency virus type-1 integrase
-
Eich E, Petz H, Kaloga M, Schulz J, Fesen MR, Mazumder A & Pommier Y (1996) (-)-Arctigenin as a lead structure for inhibitors of human immunodeficiency virus type-1 integrase. Journal of Medicinal Chemistry 39: 86-95.
-
(1996)
Journal of Medicinal Chemistry
, vol.39
, pp. 86-95
-
-
Eich, E.1
Petz, H.2
Kaloga, M.3
Schulz, J.4
Fesen, M.R.5
Mazumder, A.6
Pommier, Y.7
-
45
-
-
0029145047
-
The DNA-binding domain of HIV-1 integrase has an SH3-like fold
-
Eijkelenboom AP, Lutzke RA, Boelens R, Plasterk RH, Kaptein R & Hard K (1995) The DNA-binding domain of HIV-1 integrase has an SH3-like fold. Nature Structural Biology 2: 807-810.
-
(1995)
Nature Structural Biology
, vol.2
, pp. 807-810
-
-
Eijkelenboom, A.P.1
Lutzke, R.A.2
Boelens, R.3
Plasterk, R.H.4
Kaptein, R.5
Hard, K.6
-
46
-
-
0028239062
-
A stable complex between integrase and viral DNA ends mediates human immunodeficiency virus integration in vitro
-
Ellison V & Brown PO (1994) A stable complex between integrase and viral DNA ends mediates human immunodeficiency virus integration in vitro. Proceedings of the National Academy of Sciences, USA 91: 7316-7320.
-
(1994)
Proceedings of the National Academy of Sciences, USA
, vol.91
, pp. 7316-7320
-
-
Ellison, V.1
Brown, P.O.2
-
47
-
-
0025337327
-
Human immunodeficiency in a cell-free system
-
Ellison V, Abrams H, Roe T, Lifson J & Brown P (1990) Human immunodeficiency in a cell-free system. Journal of Virology 64: 2711-2715.
-
(1990)
Journal of Virology
, vol.64
, pp. 2711-2715
-
-
Ellison, V.1
Abrams, H.2
Roe, T.3
Lifson, J.4
Brown, P.5
-
48
-
-
0026649557
-
Identification of conserved amino acid residues critical for human immunodeficiency virus type I integrase function in vino
-
Engelman A & Craigie R (1992) Identification of conserved amino acid residues critical for human immunodeficiency virus type I integrase function in vino. Journal of Virology 66: 6361-6169.
-
(1992)
Journal of Virology
, vol.66
, pp. 6361-16169
-
-
Engelman, A.1
Craigie, R.2
-
49
-
-
0029083428
-
Efficient magnesium-dependent human immunodeficiency virus type 1 integrase activity
-
Engelman A & Craigie R (1995) Efficient magnesium-dependent human immunodeficiency virus type 1 integrase activity. Journal of Virology 69: 5908-5911.
-
(1995)
Journal of Virology
, vol.69
, pp. 5908-5911
-
-
Engelman, A.1
Craigie, R.2
-
50
-
-
0026330796
-
HIV-1 DNA integration: Mechanism of viral DNA cleavage and DNA strand transfer
-
Engelman A, Mizuuchi K & Craigie R (1991) HIV-1 DNA integration: mechanism of viral DNA cleavage and DNA strand transfer. Cell 67: 1211-1221.
-
(1991)
Cell
, vol.67
, pp. 1211-1221
-
-
Engelman, A.1
Mizuuchi, K.2
Craigie, R.3
-
51
-
-
0027179694
-
Identification of discrete functional domains of HIV-1 integrase and their organization within an active multimeric complex
-
Engelman A, Bushman FD & Craigie R (1993) Identification of discrete functional domains of HIV-1 integrase and their organization within an active multimeric complex. EMBO Journal 12: 3269-3275.
-
(1993)
EMBO Journal
, vol.12
, pp. 3269-3275
-
-
Engelman, A.1
Bushman, F.D.2
Craigie, R.3
-
52
-
-
0028067324
-
The core and carboxyl-terminal domains of the integrase protein of human immunodeficiency virus type 1 each contribute to nonspecific DNA binding
-
Engelman A, Hickman AB & Craigie R (1994) The core and carboxyl-terminal domains of the integrase protein of human immunodeficiency virus type 1 each contribute to nonspecific DNA binding. Journal of Virology 68: 5911-5917.
-
(1994)
Journal of Virology
, vol.68
, pp. 5911-5917
-
-
Engelman, A.1
Hickman, A.B.2
Craigie, R.3
-
53
-
-
0028915128
-
Multiple effects of mutations in human immunodeficiency virus type 1 integrase on viral replication
-
Engelman A, Englund G, Orenstein JM, Martin MA & Craigie R (1995) Multiple effects of mutations in human immunodeficiency virus type 1 integrase on viral replication. Journal of Virology 69: 2729-2736.
-
(1995)
Journal of Virology
, vol.69
, pp. 2729-2736
-
-
Engelman, A.1
Englund, G.2
Orenstein, J.M.3
Martin, M.A.4
Craigie, R.5
-
54
-
-
0030988998
-
Structure-based mutagenesis of the catalytic domain of human immunodeficiency virus type 1 integrase
-
Engelman A, Liu Y, Chen H, Farzan M & Dyda F (1997) Structure-based mutagenesis of the catalytic domain of human immunodeficiency virus type 1 integrase. Journal of Virology 71: 3507-3514.
-
(1997)
Journal of Virology
, vol.71
, pp. 3507-3514
-
-
Engelman, A.1
Liu, Y.2
Chen, H.3
Farzan, M.4
Dyda, F.5
-
55
-
-
0025968854
-
Determination of viral proteins present in the human immunodeficiency virus type 1 preintegration complex
-
Farnet CM & Haseltine WA (1991) Determination of viral proteins present in the human immunodeficiency virus type 1 preintegration complex. Journal of Virology 65: 1910-1915.
-
(1991)
Journal of Virology
, vol.65
, pp. 1910-1915
-
-
Farnet, C.M.1
Haseltine, W.A.2
-
56
-
-
0029845980
-
Differential inhibition of HIV-1 preintegration complexes and purified integrase protein by small molecules
-
Farnet CM, Wang B, Lipford JR & Bushman FD (1996a) Differential inhibition of HIV-1 preintegration complexes and purified integrase protein by small molecules. Proceedings of the National Academy of Sciences, USA 93: 9742-9747.
-
(1996)
Proceedings of the National Academy of Sciences, USA
, vol.93
, pp. 9742-9747
-
-
Farnet, C.M.1
Wang, B.2
Lipford, J.R.3
Bushman, F.D.4
-
57
-
-
0001996953
-
HIV cDNA integration: Molecular biology and inhibitor development
-
Farnet CM & Bushman FD (1996b) HIV cDNA integration: molecular biology and inhibitor development. AIDS 10 (supplement A) 53-511.
-
(1996)
AIDS
, vol.10
, Issue.SUPPL. A
, pp. 53-511
-
-
Farnet, C.M.1
Bushman, F.D.2
-
58
-
-
0025053617
-
Functional similarities between retroviruses and the IS3 family of bacterial insertion sequences?
-
Fayet O, Ramond P, Polard P, Prère MF & Chandler M (1990) Functional similarities between retroviruses and the IS3 family of bacterial insertion sequences? Molecular Microbiology 4: 1771-1777.
-
(1990)
Molecular Microbiology
, vol.4
, pp. 1771-1777
-
-
Fayet, O.1
Ramond, P.2
Polard, P.3
Prère, M.F.4
Chandler, M.5
-
59
-
-
0027457192
-
Inhibitors of human immunodeficiency virus integrase
-
Fesen MR, Kohn KW, Leteurtre F & Pommier Y (1993) Inhibitors of human immunodeficiency virus integrase. Proceedings of the National Academy of Sciences, USA 90: 2399-2403.
-
(1993)
Proceedings of the National Academy of Sciences, USA
, vol.90
, pp. 2399-2403
-
-
Fesen, M.R.1
Kohn, K.W.2
Leteurtre, F.3
Pommier, Y.4
-
60
-
-
0028070994
-
Inhibition of HIV-1 integrase by flavones, caffeic acid phenethyl ester (CAPE) and related compounds
-
Fesen MR, Pommier Y, Leteurtre F, Hiroguchi S, Yung J & Kohn KW (1994) Inhibition of HIV-1 integrase by flavones, caffeic acid phenethyl ester (CAPE) and related compounds. Biochemical Pharmacology 48: 595-608.
-
(1994)
Biochemical Pharmacology
, vol.48
, pp. 595-608
-
-
Fesen, M.R.1
Pommier, Y.2
Leteurtre, F.3
Hiroguchi, S.4
Yung, J.5
Kohn, K.W.6
-
61
-
-
0026760582
-
Concerted integration of viral DNA termini by purified avian mveloblastosis virus integrase
-
Fitzgerald ML, Vora AC, Zeh WG & Grandgenett DP (1992) Concerted integration of viral DNA termini by purified avian mveloblastosis virus integrase. Journal of Virology 66: 6257-6263.
-
(1992)
Journal of Virology
, vol.66
, pp. 6257-6263
-
-
Fitzgerald, M.L.1
Vora, A.C.2
Zeh, W.G.3
Grandgenett, D.P.4
-
62
-
-
0029917395
-
Nuclear import and cell cycle arrest functions of the HIV-1 Vpr protein are encoded by two separate genes in HIV-2/SIV(SM)
-
Fletcher TM, Brichacek B, Sharova N, Newman MA, Stivahtis G, Sharp PM, Emerman M, Hahn BH & Stevenson M (1996) Nuclear import and cell cycle arrest functions of the HIV-1 Vpr protein are encoded by two separate genes in HIV-2/SIV(SM). EMBO Journal 15: 6155-6165.
-
(1996)
EMBO Journal
, vol.15
, pp. 6155-6165
-
-
Fletcher, T.M.1
Brichacek, B.2
Sharova, N.3
Newman, M.A.4
Stivahtis, G.5
Sharp, P.M.6
Emerman, M.7
Hahn, B.H.8
Stevenson, M.9
-
63
-
-
0028839344
-
HIV nuclear import is governed by the phophotyrosine-mediated binding of the matrix to the core domain of integrase
-
Gallay P, Swingler S, Song J, Bushman F & Trono D (1995) HIV nuclear import is governed by the phophotyrosine-mediated binding of the matrix to the core domain of integrase. Cell 83: 569-576.
-
(1995)
Cell
, vol.83
, pp. 569-576
-
-
Gallay, P.1
Swingler, S.2
Song, J.3
Bushman, F.4
Trono, D.5
-
64
-
-
0027102597
-
Genetic of retroviral integration
-
Goff SP (1992) Genetic of retroviral integration. Annual Review of Genetics 26: 527-544.
-
(1992)
Annual Review of Genetics
, vol.26
, pp. 527-544
-
-
Goff, S.P.1
-
65
-
-
0029094543
-
Concerted integration of retrovirus-like DNA by human immunodeficiency virus type 1 integrase
-
Goodarzi G, Im G-J, Brackmann K & Grandgenett D (1995) Concerted integration of retrovirus-like DNA by human immunodeficiency virus type 1 integrase. Journal of Virology 69: 1090-1097.
-
(1995)
Journal of Virology
, vol.69
, pp. 1090-1097
-
-
Goodarzi, G.1
Im, G.-J.2
Brackmann, K.3
Grandgenett, D.4
-
66
-
-
0030908147
-
Host site selection for concerted integration by human immunodeficiency virus type 1 virions in vitro
-
Goodarzi G, Chiu R, Brackmann K, Kohn KW, Pommier Y & Grandgenett DP (1997) Host site selection for concerted integration by human immunodeficiency virus type 1 virions in vitro. Virology 231: 210-217.
-
(1997)
Virology
, vol.231
, pp. 210-217
-
-
Goodarzi, G.1
Chiu, R.2
Brackmann, K.3
Kohn, K.W.4
Pommier, Y.5
Grandgenett, D.P.6
-
68
-
-
0028145716
-
Viral long terminal repeat substrate binding characteristics of the human immunodeficiency virus type 1 integrase
-
Hazuda DJ, Wolfe AL, Hastings JC, Robbins HL, Graham PL, LaFemina RL & Emini EA (1994a) Viral long terminal repeat substrate binding characteristics of the human immunodeficiency virus type 1 integrase. Journal of Biological Chemistry 269: 3999-4004.
-
(1994)
Journal of Biological Chemistry
, vol.269
, pp. 3999-4004
-
-
Hazuda, D.J.1
Wolfe, A.L.2
Hastings, J.C.3
Robbins, H.L.4
Graham, P.L.5
LaFemina, R.L.6
Emini, E.A.7
-
70
-
-
0031060473
-
Equivalent inhibition of half-site and full-site retroviral strand transfer reactions by structurally diverse compounds
-
Hazuda D, Felock P, Hastings J, Pramanik B, Wolfe A, Goodarzi G, Vora A, Brackmann K & Grandgenett D (1997) Equivalent inhibition of half-site and full-site retroviral strand transfer reactions by structurally diverse compounds. Journal of Virology 71: 807-811.
-
(1997)
Journal of Virology
, vol.71
, pp. 807-811
-
-
Hazuda, D.1
Felock, P.2
Hastings, J.3
Pramanik, B.4
Wolfe, A.5
Goodarzi, G.6
Vora, A.7
Brackmann, K.8
Grandgenett, D.9
-
71
-
-
0030933554
-
Discovery of human immunodeficiency virus type 1 integrase inhibitors by pharmacophore searching
-
Hong H, Neamati N, Wang S, Nicklaus M, Mazumder A, Zhao H, Burke TR, Pommier Y & Milne GWA (1997) Discovery of human immunodeficiency virus type 1 integrase inhibitors by pharmacophore searching. Journal of Medicinal Chemistry 40: 930-936.
-
(1997)
Journal of Medicinal Chemistry
, vol.40
, pp. 930-936
-
-
Hong, H.1
Neamati, N.2
Wang, S.3
Nicklaus, M.4
Mazumder, A.5
Zhao, H.6
Burke, T.R.7
Pommier, Y.8
Gwa, M.9
-
72
-
-
0029980485
-
A soluble active mutant of HIV-1 integrase: Involvement of both the core and carboxyl-terminal domains in multimerization
-
Jenkins TM, Engelman A, Ghirlando R & Craigie R (1996) A soluble active mutant of HIV-1 integrase: involvement of both the core and carboxyl-terminal domains in multimerization. Journal of Biological Chemistry 271: 7712-7718.
-
(1996)
Journal of Biological Chemistry
, vol.271
, pp. 7712-7718
-
-
Jenkins, T.M.1
Engelman, A.2
Ghirlando, R.3
Craigie, R.4
-
73
-
-
0027404102
-
Characterization of the forward and reverse integration reactions of the Moloney murine leukemia virus integrase protein purified from Escherichia coli
-
Jonsson CB, Donzella GA & Roth MJ (1993) Characterization of the forward and reverse integration reactions of the Moloney murine leukemia virus integrase protein purified from Escherichia coli. Journal of Biological Chemistry 268: 1462-1469.
-
(1993)
Journal of Biological Chemistry
, vol.268
, pp. 1462-1469
-
-
Jonsson, C.B.1
Donzella, G.A.2
Roth, M.J.3
-
74
-
-
1842302312
-
Protein-protein interactions of HIV-1 IN: INI-1 (IN Interactor-1), a novel human gene with sequence similarity to yeast transcription factor SNF5
-
Kalpana GV & Goff SP (1994) Protein-protein interactions of HIV-1 IN: INI-1 (IN Interactor-1), a novel human gene with sequence similarity to yeast transcription factor SNF5. Journal of Cellular Biochemistry 18B: 27.
-
(1994)
Journal of Cellular Biochemistry
, vol.18 B
, pp. 27
-
-
Kalpana, G.V.1
Goff, S.P.2
-
75
-
-
0028566214
-
Binding and stimulation of HIV-1 integrase by a human homolog of yeast transcription factor SNF5
-
Kalpana GV, Marmon S, Wang W, Crabtree GR & Goff SP (1994) Binding and stimulation of HIV-1 integrase by a human homolog of yeast transcription factor SNF5. Science 266: 2002-2006.
-
(1994)
Science
, vol.266
, pp. 2002-2006
-
-
Kalpana, G.V.1
Marmon, S.2
Wang, W.3
Crabtree, G.R.4
Goff, S.P.5
-
76
-
-
0029861955
-
Influence of subterminal viral DNA nucleotide on differential susceptibility to cleavage by human immunodeficiency virus type 1 and visna virus integrases
-
Katzman M & Sudol M (1996) Influence of subterminal viral DNA nucleotide on differential susceptibility to cleavage by human immunodeficiency virus type 1 and visna virus integrases. Journal of Virology 70: 9069-9073.
-
(1996)
Journal of Virology
, vol.70
, pp. 9069-9073
-
-
Katzman, M.1
Sudol, M.2
-
77
-
-
0024431589
-
The avian retroviral integration protein cleaves the terminal sequences of linear viral DNA at the in vivo sites of integration
-
Katzman M, Katz RA, Skalka AM & Leis J (1989) The avian retroviral integration protein cleaves the terminal sequences of linear viral DNA at the in vivo sites of integration. Journal of Virology 63: 5319-5327.
-
(1989)
Journal of Virology
, vol.63
, pp. 5319-5327
-
-
Katzman, M.1
Katz, R.A.2
Skalka, A.M.3
Leis, J.4
-
78
-
-
0026035178
-
Retroviral integrase domains: DNA binding and the recognition of LTR sequences
-
Erratum 19: 1358
-
Khan E, Mack JP, Katz RA, Kulkosky J & Skalka AM (1991) Retroviral integrase domains: DNA binding and the recognition of LTR sequences. Nucleic Acids Research 19: 851-860; Erratum 19: 1358.
-
(1991)
Nucleic Acids Research
, vol.19
, pp. 851-860
-
-
Khan, E.1
Mack, J.P.2
Katz, R.A.3
Kulkosky, J.4
Skalka, A.M.5
-
80
-
-
0028790504
-
Enhanced and coordinated processing of synapsed viral DNA ends by retroviral integrases in vitro
-
Kukolj G & Skalka AM (1995) Enhanced and coordinated processing of synapsed viral DNA ends by retroviral integrases in vitro. Genes and Development 9: 2556-2567.
-
(1995)
Genes and Development
, vol.9
, pp. 2556-2567
-
-
Kukolj, G.1
Skalka, A.M.2
-
81
-
-
0031060369
-
Subcellular localization of avian sarcoma virus and human immunodeficiency virus type 1 integrases
-
Kukolj G, Jones KS & Skalka AM (1997) Subcellular localization of avian sarcoma virus and human immunodeficiency virus type 1 integrases. Journal of Virology 71: 843-847.
-
(1997)
Journal of Virology
, vol.71
, pp. 843-847
-
-
Kukolj, G.1
Jones, K.S.2
Skalka, A.M.3
-
83
-
-
0026719238
-
Residues critical for retroviral integrative recombination in a region that is highly conserved among retroviral/retrotransposon integrases and bacterial insertion sequence transposases
-
Kulkosky J, Jones KS, Katz RA, Mack JP & Skalka AM (1992) Residues critical for retroviral integrative recombination in a region that is highly conserved among retroviral/retrotransposon integrases and bacterial insertion sequence transposases. Molecular and Cellular Biology 12: 2331-2338.
-
(1992)
Molecular and Cellular Biology
, vol.12
, pp. 2331-2338
-
-
Kulkosky, J.1
Jones, K.S.2
Katz, R.A.3
Mack, J.P.4
Skalka, A.M.5
-
84
-
-
0026072804
-
Substrate specificity of recombinant human immunodeficiency virus integrase protein
-
LaFemina RL, Callahan PL & Cordingley MG (1991) Substrate specificity of recombinant human immunodeficiency virus integrase protein. Journal of Virology 65: 5624-5630.
-
(1991)
Journal of Virology
, vol.65
, pp. 5624-5630
-
-
LaFemina, R.L.1
Callahan, P.L.2
Cordingley, M.G.3
-
85
-
-
0026459411
-
Requirement of active human immunodeficiency virus type 1 integrase enzyme for productive infection of human T-lymphoid cells
-
LaFemina RL, Schneider CL, Robbins HL, Callahan PL, LeGrow K, Roth E, Schleif WA & Emmi EA (1992) Requirement of active human immunodeficiency virus type 1 integrase enzyme for productive infection of human T-lymphoid cells. Journal of Virology 66: 7414-7419.
-
(1992)
Journal of Virology
, vol.66
, pp. 7414-7419
-
-
LaFemina, R.L.1
Schneider, C.L.2
Robbins, H.L.3
Callahan, P.L.4
LeGrow, K.5
Roth, E.6
Schleif, W.A.7
Emmi, E.A.8
-
86
-
-
0028798026
-
Inhibition of human immunodeficiency virus integrase by bis-catechols
-
LaFemina RL, Graham PL, LeGrow K, Hastings JC, Wolfe A, Young SD, Emini EA & Hazuda D (1995) Inhibition of human immunodeficiency virus integrase by bis-catechols. Antimicrobial Agents and Chemotherapy 39: 320-324.
-
(1995)
Antimicrobial Agents and Chemotherapy
, vol.39
, pp. 320-324
-
-
LaFemina, R.L.1
Graham, P.L.2
LeGrow, K.3
Hastings, J.C.4
Wolfe, A.5
Young, S.D.6
Emini, E.A.7
Hazuda, D.8
-
87
-
-
0027258736
-
Interactions between HIV-1 nucleocapsid protein and viral DNA may have important functions in the viral life cycle
-
Lapadat-Tapolsky M, De Rocquigny H, Van Gent D, Roques B, Plasterk R & Darlix J-L (1993) Interactions between HIV-1 nucleocapsid protein and viral DNA may have important functions in the viral life cycle. Nucleic Acids Research 21: 831-839.
-
(1993)
Nucleic Acids Research
, vol.21
, pp. 831-839
-
-
Lapadat-Tapolsky, M.1
De Rocquigny, H.2
Van Gent, D.3
Roques, B.4
Plasterk, R.5
Darlix, J.-L.6
-
88
-
-
0026537415
-
Both substrate and target oligonucleotide sequences affect in vitro integration mediated by human immunodeficiency virus type 1 integrase protein produced in Saccharomyces cerevisiae
-
Leavitt AD, Rose RB & Varmus HE (1992) Both substrate and target oligonucleotide sequences affect in vitro integration mediated by human immunodeficiency virus type 1 integrase protein produced in Saccharomyces cerevisiae. Journal of Virology 66: 2359-2368.
-
(1992)
Journal of Virology
, vol.66
, pp. 2359-2368
-
-
Leavitt, A.D.1
Rose, R.B.2
Varmus, H.E.3
-
89
-
-
0027470432
-
Site-directed mutagenesis of HIV-1 integrase demonstrates differential effects on integrase functions in vitro
-
Leavitt AD, Shiue L & Varmus HE (1993) Site-directed mutagenesis of HIV-1 integrase demonstrates differential effects on integrase functions in vitro. Journal of Biological Chemistry 268: 2113-2119.
-
(1993)
Journal of Biological Chemistry
, vol.268
, pp. 2113-2119
-
-
Leavitt, A.D.1
Shiue, L.2
Varmus, H.E.3
-
90
-
-
0028077096
-
Protection of retroviral DNa from autointegration: Involvement of a cellular factor
-
Lee MS & Craigie R (1994) Protection of retroviral DNA from autointegration: involvement of a cellular factor. Proceedings of the National Academy of Sciences, USA 91: 9823-9827.
-
(1994)
Proceedings of the National Academy of Sciences, USA
, vol.91
, pp. 9823-9827
-
-
Lee, M.S.1
Craigie, R.2
-
91
-
-
0029670473
-
Zinc stimulates Mg2+-dependent 3′-processing activity of human immunodeficiency virus type 1 integrase in vitro
-
Lee SP & Han MK (1996) Zinc stimulates Mg2+-dependent 3′-processing activity of human immunodeficiency virus type 1 integrase in vitro. Biochemistry 35: 3837-3844.
-
(1996)
Biochemistry
, vol.35
, pp. 3837-3844
-
-
Lee, S.P.1
Han, M.K.2
-
92
-
-
0028984923
-
Characterization of Mg2+-dependent 3′-processing activity for human immunodeficiency virus typel integrase in vitro: Real-time kinetic studies using fluorescence resonance energy transfer
-
Lee SP, Kim HG, Censullo ML & Han MK (1995a) Characterization of Mg2+-dependent 3′-processing activity for human immunodeficiency virus typel integrase in vitro: real-time kinetic studies using fluorescence resonance energy transfer. Biochemistry 34: 10205-10214.
-
(1995)
Biochemistry
, vol.34
, pp. 10205-10214
-
-
Lee, S.P.1
Kim, H.G.2
Censullo, M.L.3
Han, M.K.4
-
93
-
-
0029091789
-
Substrate-length-dependent activities of human immunodeficiency type 1 integrase in vitro: Differential DNA binding affinities associated with different lengths of substrates
-
Lee SP, Censullo ML, Kim HG & Han MK (1995b) Substrate-length-dependent activities of human immunodeficiency type 1 integrase in vitro: differential DNA binding affinities associated with different lengths of substrates. Biochemistry 34: 10215-10223.
-
(1995)
Biochemistry
, vol.34
, pp. 10215-10223
-
-
Lee, S.P.1
Censullo, M.L.2
Kim, H.G.3
Han, M.K.4
-
94
-
-
0030614408
-
Zn2+ promotes the self-association of human immunodeficiency virus type-1 integrase in vitro
-
Lee SP, Xiao J, Knutson JR, Lewis MS & Han MK (1997) Zn2+ promotes the self-association of human immunodeficiency virus type-1 integrase in vitro. Biochemistry 36: 173-180.
-
(1997)
Biochemistry
, vol.36
, pp. 173-180
-
-
Lee, S.P.1
Xiao, J.2
Knutson, J.R.3
Lewis, M.S.4
Han, M.K.5
-
95
-
-
0028981211
-
Inhibition of the integrase immunodeficiencv virus (HIV) type 1 by anti-HIV plant proteins MAP30 and GAP31
-
Lee-Huang S, Huang PL, Huang PL, Bourinbaiar AS, Chen H-C & Kung H-F (1995) Inhibition of the integrase immunodeficiencv virus (HIV) type 1 by anti-HIV plant proteins MAP30 and GAP31. Proceedings of the National Academy of Sciences, USA 92: 8818-8822.
-
(1995)
Proceedings of the National Academy of Sciences, USA
, vol.92
, pp. 8818-8822
-
-
Lee-Huang, S.1
Huang, P.L.2
Huang, P.L.3
Bourinbaiar, A.S.4
Chen, H.-C.5
Kung, H.-F.6
-
96
-
-
10344256143
-
Intracellular expression of single-chain variable fragments to inhibit early stages of the viral life cycle by targeting human immunodeficiency virus type 1 integrase
-
Lew-Mintz P, Duan L, Zhang H, Hu B, Dornadula G, Zhu M, Kulkosky J, Bizub-Bender D, Skalka AM & Pomerantz RJ (1996) Intracellular expression of single-chain variable fragments to inhibit early stages of the viral life cycle by targeting human immunodeficiency virus type 1 integrase. Journal of Virology 70: 8821-8832.
-
(1996)
Journal of Virology
, vol.70
, pp. 8821-8832
-
-
Lew-Mintz, P.1
Duan, L.2
Zhang, H.3
Hu, B.4
Dornadula, G.5
Zhu, M.6
Kulkosky, J.7
Bizub-Bender, D.8
Skalka, A.M.9
Pomerantz, R.J.10
-
97
-
-
0028171531
-
Nucleotide binding bv the HIV-1 integrase protein in vitro
-
Lipford JR, Worland ST & Farnet CM (1994) Nucleotide binding bv the HIV-1 integrase protein in vitro. Journal of AIDS 7: 1215-1223.
-
(1994)
Journal of AIDS
, vol.7
, pp. 1215-1223
-
-
Lipford, J.R.1
Worland, S.T.2
Farnet, C.M.3
-
98
-
-
0029116747
-
Solution structure of the DNA binding domain of HIV-1 integrase
-
Lodi PJ, Ernst JA, Kuszewski J, Hickman AB, Engelman A, Craigie R, Clore GM & Gronenborn AM (1995) Solution structure of the DNA binding domain of HIV-1 integrase. Biochemistry 34: 9826-9833.
-
(1995)
Biochemistry
, vol.34
, pp. 9826-9833
-
-
Lodi, P.J.1
Ernst, J.A.2
Kuszewski, J.3
Hickman, A.B.4
Engelman, A.5
Craigie, R.6
Clore, G.M.7
Gronenborn, A.M.8
-
99
-
-
0028034050
-
Characterization of the minimal DNA-binding domain of the HIV integrase protein
-
Lutzke RAP, Vink C & Plasterk RHA (1994) Characterization of the minimal DNA-binding domain of the HIV integrase protein. Nucleic Acids Research 22: 4125-4131.
-
(1994)
Nucleic Acids Research
, vol.22
, pp. 4125-4131
-
-
Rap, L.1
Vink, C.2
Plasterk, R.H.A.3
-
100
-
-
0029557124
-
Identification of a hexapeptide inhibitor of the human immunodeficiency virus integrase protein by using a combinatorial chemical library
-
Lutzke RAP, Eppens NA, Weber PA, Houghten RA & Plasterk RHA (1995) Identification of a hexapeptide inhibitor of the human immunodeficiency virus integrase protein by using a combinatorial chemical library. Proceedings of the National Academy of Sciences, USA 92: 11456-11460.
-
(1995)
Proceedings of the National Academy of Sciences, USA
, vol.92
, pp. 11456-11460
-
-
Lutzke, R.A.P.1
Eppens, N.A.2
Weber, P.A.3
Houghten, R.A.4
Plasterk, R.H.A.5
-
101
-
-
0029166510
-
Processing of deoxyuridine mismatches and abasic sites by human immunodeficiency virus type I integrase
-
Mazumder A & Pommier Y (1995) Processing of deoxyuridine mismatches and abasic sites by human immunodeficiency virus type I integrase. Nucleic Acids Research 23: 2865-2871.
-
(1995)
Nucleic Acids Research
, vol.23
, pp. 2865-2871
-
-
Mazumder, A.1
Pommier, Y.2
-
102
-
-
0028352363
-
Intermolecular disintegration and intramolecular strand transfer activities of wild-type and mutant HIV-1 integrase
-
Mazumder A, Engelman A, Craigie R, Fesen M & Pommier Y (1994a) Intermolecular disintegration and intramolecular strand transfer activities of wild-type and mutant HIV-1 integrase. Nucleic Acids Research 22: 1037-1043.
-
(1994)
Nucleic Acids Research
, vol.22
, pp. 1037-1043
-
-
Mazumder, A.1
Engelman, A.2
Craigie, R.3
Fesen, M.4
Pommier, Y.5
-
103
-
-
0028020102
-
Methylphosphonodiester substitution near the conserved CA dinucleotide in the HIV LTR alters both the extent of 3′-processing and choice of nucleophile by HIV-1 integrase
-
Mazumder A, Gupta M & Pommier Y (1994b) Methylphosphonodiester substitution near the conserved CA dinucleotide in the HIV LTR alters both the extent of 3′-processing and choice of nucleophile by HIV-1 integrase. Nucleic Acids Research 22: 4441-4448.
-
(1994)
Nucleic Acids Research
, vol.22
, pp. 4441-4448
-
-
Mazumder, A.1
Gupta, M.2
Pommier, Y.3
-
104
-
-
0028242724
-
Inhibition of human immunodeficiency virus type 1 integrase by 3′-azido-3′-deoxythymidylate
-
Mazumder A, Cooney D, Agbaria R, Gupta M & Pommier Y (1994c) Inhibition of human immunodeficiency virus type 1 integrase by 3′-azido-3′-deoxythymidylate. Proceedings of the National Academy of Sciences, USA 91: 5771-5775.
-
(1994)
Proceedings of the National Academy of Sciences, USA
, vol.91
, pp. 5771-5775
-
-
Mazumder, A.1
Cooney, D.2
Agbaria, R.3
Gupta, M.4
Pommier, Y.5
-
105
-
-
0029062402
-
Inhibition of human immunodeficiency virus type 1 integrase by a hydrophobic cation: The phenanthrolinecuprous complex
-
Mazumder A, Gupta M, Perrin DM, Sigman DS, Rabinovitz M & Pommier Y (1995a) Inhibition of human immunodeficiency virus type 1 integrase by a hydrophobic cation: the phenanthrolinecuprous complex. AIDS Research and Human Retroviruses 11: 115-125.
-
(1995)
AIDS Research and Human Retroviruses
, vol.11
, pp. 115-125
-
-
Mazumder, A.1
Gupta, M.2
Perrin, D.M.3
Sigman, D.S.4
Rabinovitz, M.5
Pommier, Y.6
-
106
-
-
0028820595
-
Effects of tyrphostins, protein kinase inhibitors, on human immunodeficiency virus type 1 integrase
-
Mazumder A, Gazit A, Levitzki A, Nicklaus M, Yung J, Kohlhagen G & Pommier Y (1995b) Effects of tyrphostins, protein kinase inhibitors, on human immunodeficiency virus type 1 integrase. Biochemistry 34: 15111-15121.
-
(1995)
Biochemistry
, vol.34
, pp. 15111-15121
-
-
Mazumder, A.1
Gazit, A.2
Levitzki, A.3
Nicklaus, M.4
Yung, J.5
Kohlhagen, G.6
Pommier, Y.7
-
107
-
-
0028928463
-
Inhibition of human immunodeficiency virus type-1 integrase by curcumin
-
Mazumder A, Raghavan K, Weinstein J, Kohn KW & Pommier Y (1995c) Inhibition of human immunodeficiency virus type-1 integrase by curcumin. Biochemical Pharmacology 49: 1165-1170.
-
(1995)
Biochemical Pharmacology
, vol.49
, pp. 1165-1170
-
-
Mazumder, A.1
Raghavan, K.2
Weinstein, J.3
Kohn, K.W.4
Pommier, Y.5
-
108
-
-
0029964978
-
Inhibition of human immunodeficiency virus type 1 integrase by guanosine quartet structures
-
Mazumder A, Neamati N, Ojwang JO, Sunder S, Rando RF & Pommier Y (1996a) Inhibition of human immunodeficiency virus type 1 integrase by guanosine quartet structures. Biochemistry 43: 13762-13771.
-
(1996)
Biochemistry
, vol.43
, pp. 13762-13771
-
-
Mazumder, A.1
Neamati, N.2
Ojwang, J.O.3
Sunder, S.4
Rando, R.F.5
Pommier, Y.6
-
109
-
-
0029864507
-
Chemical trapping of ternary complexes of human immunodeficiency virus type 1 integrase, divalent metal, and DNA substrates containing an abasic site
-
Mazumder A, Neamati N, Pilon A, Sunder S & Pommier Y (1996b) Chemical trapping of ternary complexes of human immunodeficiency virus type 1 integrase, divalent metal, and DNA substrates containing an abasic site. Journal of Biological Chemistry 271: 27330-27338.
-
(1996)
Journal of Biological Chemistry
, vol.271
, pp. 27330-27338
-
-
Mazumder, A.1
Neamati, N.2
Pilon, A.3
Sunder, S.4
Pommier, Y.5
-
110
-
-
0029871472
-
Effects of nucleotide analogs on human immunodeficiency virus type 1 integrase
-
Mazumder A, Neamati N, Sommadossi J-P, Gosselin G, Schinazi R, Imbach J-L & Pommier Y (1996c) Effects of nucleotide analogs on human immunodeficiency virus type 1 integrase. Molecular Pharmacology 49: 621-628.
-
(1996)
Molecular Pharmacology
, vol.49
, pp. 621-628
-
-
Mazumder, A.1
Neamati, N.2
Sommadossi, J.-P.3
Gosselin, G.4
Schinazi, R.5
Imbach, J.-L.6
Pommier, Y.7
-
111
-
-
15844424316
-
Antiretroviral agent as inhibitors of both human immunodeficiency virus type 1 integrase and protease
-
Mazumder A, Wang S, Neamati N, Nicklaus M, Sunder S, Chen J, Milne G, Rice WG, Burke TR & Pommier Y (1996d) Antiretroviral agent as inhibitors of both human immunodeficiency virus type 1 integrase and protease. Journal of Medicinal Chemistry 39: 2472-2481.
-
(1996)
Journal of Medicinal Chemistry
, vol.39
, pp. 2472-2481
-
-
Mazumder, A.1
Wang, S.2
Neamati, N.3
Nicklaus, M.4
Sunder, S.5
Chen, J.6
Milne, G.7
Rice, W.G.8
Burke, T.R.9
Pommier, Y.10
-
112
-
-
1842285050
-
Retroviral integrase: A novel target in antiviral drug development: basic in vitro assays with the purified enzyme
-
Edited by D Kinchington and R Schinazi. Totowa, NJ: Humana Press (in press)
-
Mazumder A, Neamati N, Sunder S, Owen J & Pommier Y (1997a) Retroviral integrase: a novel target in antiviral drug development: basic in vitro assays with the purified enzyme. In Methods in Cellular and Molecular Biology: Antiviral Evaluation. Edited by D Kinchington and R Schinazi. Totowa, NJ: Humana Press (in press).
-
(1997)
Methods in Cellular and Molecular Biology: Antiviral Evaluation
-
-
Mazumder, A.1
Neamati, N.2
Sunder, S.3
Owen, J.4
Pommier, Y.5
-
113
-
-
0030902155
-
Probing interactions between viral DNA and human immunodeficiency virus type 1 integrase using dinucleotides
-
Mazumder A, Uchida H, Neamati N, Sunder S, Jaworska-Maslanka M, Wickstrom E, Zeng F, Jones RA, Mandes RF, Chenault HK & Pommier Y (1997b) Probing interactions between viral DNA and human immunodeficiency virus type 1 integrase using dinucleotides. Molecular Pharmacology 51: 567-575.
-
(1997)
Molecular Pharmacology
, vol.51
, pp. 567-575
-
-
Mazumder, A.1
Uchida, H.2
Neamati, N.3
Sunder, S.4
Jaworska-Maslanka, M.5
Wickstrom, E.6
Zeng, F.7
Jones, R.A.8
Mandes, R.F.9
Chenault, H.K.10
Pommier, Y.11
-
114
-
-
0030972160
-
Human immunodeficiency virus type 1 preintegration complexes: Studies of organization and composition
-
Miller MD, Farnet CM & Bushman FD (1997) Human immunodeficiency virus type 1 preintegration complexes: studies of organization and composition. Journal of Virology 71: 5382-5390.
-
(1997)
Journal of Virology
, vol.71
, pp. 5382-5390
-
-
Miller, M.D.1
Farnet, C.M.2
Bushman, F.D.3
-
115
-
-
0026799383
-
Polynucleotidyl transfer reactions in transpositional DNA recombination
-
Mizuuchi K (1992) Polynucleotidyl transfer reactions in transpositional DNA recombination. Cell 267: 21273-21276.
-
(1992)
Cell
, vol.267
, pp. 21273-21276
-
-
Mizuuchi, K.1
-
116
-
-
0028142815
-
Triplex-mediated inhibition of HIV DNA integration in vitro
-
Mouscadet J-F, Carteau S, Goulaouic H, Subra F & Auclair C (1994a) Triplex-mediated inhibition of HIV DNA integration in vitro. Journal of Biological Chemistry 269: 21634-21638.
-
(1994)
Journal of Biological Chemistry
, vol.269
, pp. 21634-21638
-
-
Mouscadet, J.-F.1
Carteau, S.2
Goulaouic, H.3
Subra, F.4
Auclair, C.5
-
117
-
-
0028288222
-
Triple helix formation with short oligonucleotide-intercalator conjugates matching the HIV-1 U3 LTR end sequence
-
Mouscadet J-F, Ketterlé C, Goulaouic H, Carteau S, Subra F, Le Bret M & Auclair C (1994b) Triple helix formation with short oligonucleotide-intercalator conjugates matching the HIV-1 U3 LTR end sequence. Biochemistry 33: 4187-4196.
-
(1994)
Biochemistry
, vol.33
, pp. 4187-4196
-
-
Mouscadet, J.-F.1
Ketterlé, C.2
Goulaouic, H.3
Carteau, S.4
Subra, F.5
Le Bret, M.6
Auclair, C.7
-
118
-
-
0027136287
-
Rapid solution assays for retroviral integration reactions and their use in kinetic analyses of wild-type and mutant Rous sarcoma virus integrases
-
Müller B, Jones KS, Merkel GW & Skalka AM (1993) Rapid solution assays for retroviral integration reactions and their use in kinetic analyses of wild-type and mutant Rous sarcoma virus integrases. Proceedings of the National Academy of Sciences, USA 90: 11633-11637.
-
(1993)
Proceedings of the National Academy of Sciences, USA
, vol.90
, pp. 11633-11637
-
-
Müller, B.1
Jones, K.S.2
Merkel, G.W.3
Skalka, A.M.4
-
119
-
-
0028067639
-
DNA bending creates favored sites for retroviral integration: An explanation for preferred insertion sites in nucleosomes
-
Müller H-P & Varmus HE (1994) DNA bending creates favored sites for retroviral integration: an explanation for preferred insertion sites in nucleosomes. EMBO Journal 13: 4704-4714.
-
(1994)
EMBO Journal
, vol.13
, pp. 4704-4714
-
-
Müller, H.-P.1
Varmus, H.E.2
-
120
-
-
0026652466
-
A mutation at one end of Moloney murine leukemia virus DNA blocks cleavage of both ends by the viral integrase in vivo
-
Murphy JE & Goff SP (1992) A mutation at one end of Moloney murine leukemia virus DNA blocks cleavage of both ends by the viral integrase in vivo. Journal of Virology 66: 5092-5095.
-
(1992)
Journal of Virology
, vol.66
, pp. 5092-5095
-
-
Murphy, J.E.1
Goff, S.P.2
-
121
-
-
0029810902
-
Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-κB
-
Natarajan K, Singh S, Burke TR, Grunberger D & Aggarwal BB (1996) Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-κB. Proceedings of the National Academy of Sciences, USA 93: 9090-9095.
-
(1996)
Proceedings of the National Academy of Sciences, USA
, vol.93
, pp. 9090-9095
-
-
Natarajan, K.1
Singh, S.2
Burke, T.R.3
Grunberger, D.4
Aggarwal, B.B.5
-
122
-
-
0030855938
-
Design and discovery of HIV-1 integrase inhibitors
-
Neamati N, Sunder S & Pommier Y (1997a) Design and discovery of HIV-1 integrase inhibitors. Drug Discovery Today 2: 487-498..
-
(1997)
Drug Discovery Today
, vol.2
, pp. 487-498
-
-
Neamati, N.1
Sunder, S.2
Pommier, Y.3
-
123
-
-
0031046693
-
Diarylsulfones, a novel class of HIV-1 integrase inhibitors
-
Neamati N, Mazumder A, Zhao H, Sunder S, Burke TR, Schultz RJ & Pommier Y (1997b) Diarylsulfones, a novel class of HIV-1 integrase inhibitors. Antimicrobial Agents and Chemotherapy 41: 385-393.
-
(1997)
Antimicrobial Agents and Chemotherapy
, vol.41
, pp. 385-393
-
-
Neamati, N.1
Mazumder, A.2
Zhao, H.3
Sunder, S.4
Burke, T.R.5
Schultz, R.J.6
Pommier, Y.7
-
124
-
-
0030891930
-
Depside and depsidones as inhibitors of HIV-1 integrase: Discovery of novel inhibitors through 3D database searching
-
Neamati N, Hong H, Mazumder A, Wang S, Sunder S, Nicklaus MC, Milne GWA, Proska B & Pommier Y (1997c) Depside and depsidones as inhibitors of HIV-1 integrase: discovery of novel inhibitors through 3D database searching. Journal of Medicinal Chemistry 40: 942-951.
-
(1997)
Journal of Medicinal Chemistry
, vol.40
, pp. 942-951
-
-
Neamati, N.1
Hong, H.2
Mazumder, A.3
Wang, S.4
Sunder, S.5
Nicklaus, M.C.6
Milne, G.W.A.7
Proska, B.8
Pommier, Y.9
-
125
-
-
0030891601
-
HIV-1 integrase pharmacophore: Discovery of inhibitors through 3D database searching
-
Nicklaus M, Neamati N, Hong H, Mazumder A, Sunder Y, Chen J, Milne GWA & Pommier Y (1997) HIV-1 integrase pharmacophore: discovery of inhibitors through 3D database searching. Journal of Medicinal Chemistry 40: 920-929.
-
(1997)
Journal of Medicinal Chemistry
, vol.40
, pp. 920-929
-
-
Nicklaus, M.1
Neamati, N.2
Hong, H.3
Mazumder, A.4
Sunder, Y.5
Chen, J.6
Milne, G.W.A.7
Pommier, Y.8
-
126
-
-
0029670765
-
Monoclonal antibodies against human immunodeficiency virus type 1 integrase: Epitope mapping and differential effects on integrase activities in vitro
-
Nilsen BM, Haugan IR, Berg K, Olsen L, Brown PO & Helland DE (1996) Monoclonal antibodies against human immunodeficiency virus type 1 integrase: epitope mapping and differential effects on integrase activities in vitro. Journal of Virology 70: 1580-1587.
-
(1996)
Journal of Virology
, vol.70
, pp. 1580-1587
-
-
Nilsen, B.M.1
Haugan, I.R.2
Berg, K.3
Olsen, L.4
Brown, P.O.5
Helland, D.E.6
-
127
-
-
0028824505
-
T30177, an oligonucleotide stabilized by an intramolecular guanosine octet, is a potent inhibitor of laboratory strains and clinical isolates of human immunodeficiency virus type 1
-
Ojwang JO, Buckheit RW, Pommier Y, Mazumder A, de Vreese K, Esté IA Reymen D, Pallansch LA, Lackman-Smith C, Wallace TL, De Clercq E, McGrath MS & Rando RF (1995) T30177, an oligonucleotide stabilized by an intramolecular guanosine octet, is a potent inhibitor of laboratory strains and clinical isolates of human immunodeficiency virus type 1. Antimicrobial Agents and Chemotherapy 39: 2426-2435.
-
(1995)
Antimicrobial Agents and Chemotherapy
, vol.39
, pp. 2426-2435
-
-
Ojwang, J.O.1
Buckheit, R.W.2
Pommier, Y.3
Mazumder, A.4
De Vreese, K.5
Esté, I.A.6
Reymen, D.7
Pallansch, L.A.8
Lackman-Smith, C.9
Wallace, T.L.10
De Clercq, E.11
McGrath, M.S.12
Rando, R.F.13
-
128
-
-
0029870911
-
A molecular mechanics and dynamics study of alternate triple-helices involving the integrase-binding site of the HIV-1 virus and oligonucleotides having a 3′-3′ internucleotide junction
-
Ouali M, Bouziane M, Ketterle C, Gabarro-Arpa J, Auclair C & Le Bret M (1996) A molecular mechanics and dynamics study of alternate triple-helices involving the integrase-binding site of the HIV-1 virus and oligonucleotides having a 3′-3′ internucleotide junction. Journal of Biomolecular Structure and Dynamics 13: 835-853.
-
(1996)
Journal of Biomolecular Structure and Dynamics
, vol.13
, pp. 835-853
-
-
Ouali, M.1
Bouziane, M.2
Ketterle, C.3
Gabarro-Arpa, J.4
Auclair, C.5
Le Bret, M.6
-
129
-
-
0030026836
-
The metal ion-induced cooperative binding of HIV-1 integrase to DNa exhibits a marked preference for Mn(II) rather than Mg(II)
-
Pemberton IK, Buckle M & Buc H (1996) The metal ion-induced cooperative binding of HIV-1 integrase to DNA exhibits a marked preference for Mn(II) rather than Mg(II). Journal of Biological Chemistry 271: 1498-1506.
-
(1996)
Journal of Biological Chemistry
, vol.271
, pp. 1498-1506
-
-
Pemberton, I.K.1
Buckle, M.2
Buc, H.3
-
130
-
-
0000420523
-
DNA topoisomerase II inhibitors
-
Edited by BA Teicher. Totowa, NJ: Humana Press
-
Pommier Y (1997) DNA topoisomerase II inhibitors. In Cancer Therapeutics: Experimental and Clinical Agents. Edited by BA Teicher. Totowa, NJ: Humana Press, pp. 153-174.
-
(1997)
Cancer Therapeutics: Experimental and Clinical Agents
, pp. 153-174
-
-
Pommier, Y.1
-
131
-
-
0028264042
-
Human immunodeficiency virus integrase directs integration to sites of severe DNA distortion within the nucleosome core
-
Pruss D, Bushman FD & Wolffe AP (1994a) Human immunodeficiency virus integrase directs integration to sites of severe DNA distortion within the nucleosome core. Proceedings of the National Academy of Sciences, USA 91: 5913-5917.
-
(1994)
Proceedings of the National Academy of Sciences, USA
, vol.91
, pp. 5913-5917
-
-
Pruss, D.1
Bushman, F.D.2
Wolffe, A.P.3
-
132
-
-
0028125005
-
The influence of DNA and nucleosome structure on integration events directed by HIV integrase
-
Pruss D, Reeves R, Bushman FD & Wolffe AP (1994b) The influence of DNA and nucleosome structure on integration events directed by HIV integrase. Journal of Biological Chemistry 269: 25031-25041.
-
(1994)
Journal of Biological Chemistry
, vol.269
, pp. 25031-25041
-
-
Pruss, D.1
Reeves, R.2
Bushman, F.D.3
Wolffe, A.P.4
-
133
-
-
0026696624
-
Nucleosomes, DNA-binding proteins, and DNA sequence modulate retroviral integration target site selection
-
Pryciak PM & Varmus HE (1992) Nucleosomes, DNA-binding proteins, and DNA sequence modulate retroviral integration target site selection. Cell 69: 769-780.
-
(1992)
Cell
, vol.69
, pp. 769-780
-
-
Pryciak, P.M.1
Varmus, H.E.2
-
134
-
-
0026567862
-
Retroviral integration into minichromosomes in vitro
-
Pryciak PM, Sil A & Varmus HE (1992) Retroviral integration into minichromosomes in vitro. EMBO Journal 11: 291-303.
-
(1992)
EMBO Journal
, vol.11
, pp. 291-303
-
-
Pryciak, P.M.1
Sil, A.2
Varmus, H.E.3
-
135
-
-
0029122532
-
Sequences in the human immunodeficiency virus type 1 U3 region required for in vivo and in vitro integration
-
Reicin AS, Kalpana G, Paik S, Marmon S & Goff S (1995) Sequences in the human immunodeficiency virus type 1 U3 region required for in vivo and in vitro integration. Journal of Virology 69: 5904-5907.
-
(1995)
Journal of Virology
, vol.69
, pp. 5904-5907
-
-
Reicin, A.S.1
Kalpana, G.2
Paik, S.3
Marmon, S.4
Goff, S.5
-
137
-
-
10244260392
-
Dicaffeoylquinic acid inhibitors of human immunodeficiency virus integrase: Inhibition of the core catalytic domain of human immunodeficiency virus integrase
-
Robinson WE, Cordeiro M, Abdel-Malek S, Jia Q, Chow SA, Reinecke MG & Mitchell WM (1996a) Dicaffeoylquinic acid inhibitors of human immunodeficiency virus integrase: inhibition of the core catalytic domain of human immunodeficiency virus integrase. Molecular Pharmacology 50: 846-855.
-
(1996)
Molecular Pharmacology
, vol.50
, pp. 846-855
-
-
Robinson, W.E.1
Cordeiro, M.2
Abdel-Malek, S.3
Jia, Q.4
Chow, S.A.5
Reinecke, M.G.6
Mitchell, W.M.7
-
138
-
-
2642685126
-
Inhibitors of HIV-1 replication that inhibit HIV integrase
-
Robinson WE, Reinecke MG, Abdel-Malek S, Jia Q & Chow SA (1996b) Inhibitors of HIV-1 replication that inhibit HIV integrase. Proceedings of the National Academy of Sciences, USA 93: 6326-6331.
-
(1996)
Proceedings of the National Academy of Sciences, USA
, vol.93
, pp. 6326-6331
-
-
Robinson, W.E.1
Reinecke, M.G.2
Abdel-Malek, S.3
Jia, Q.4
Chow, S.A.5
-
139
-
-
0027158091
-
Integration of murine leukemia virus DNA depends on mitosis
-
Roe T, Reynolds TC, Yu G & Brown PO (1993) Integration of murine leukemia virus DNA depends on mitosis. EMBO Journal 12: 2099-2108.
-
(1993)
EMBO Journal
, vol.12
, pp. 2099-2108
-
-
Roe, T.1
Reynolds, T.C.2
Yu, G.3
Brown, P.O.4
-
140
-
-
0031032592
-
3′-End processing and kinetics of 5′-end joining during retroviral integration in vivo
-
Roe T, Chow SA & Brown PO (1997) 3′-End processing and kinetics of 5′-end joining during retroviral integration in vivo. Journal of Virology 71: 1334-1340.
-
(1997)
Journal of Virology
, vol.71
, pp. 1334-1340
-
-
Roe, T.1
Chow, S.A.2
Brown, P.O.3
-
141
-
-
0026634793
-
The N-terminal region of HIV-1 integrase is required for integration activity, but not for DNA-binding
-
Schauer M & Billich A (1992) The N-terminal region of HIV-1 integrase is required for integration activity, but not for DNA-binding. Biochemical and Biophysical Research Communications 185: 874-880.
-
(1992)
Biochemical and Biophysical Research Communications
, vol.185
, pp. 874-880
-
-
Schauer, M.1
Billich, A.2
-
142
-
-
0018069786
-
Virus-coded origin of a 32,000-dalton protein from avian retrovirus cores: Structural relatedness of p32 and the beta polypeptide of the avian retrovirus DNa polymerase
-
Schiff RD & Grandgenett DP (1978) Virus-coded origin of a 32,000-dalton protein from avian retrovirus cores: structural relatedness of p32 and the beta polypeptide of the avian retrovirus DNA polymerase. Journal of Virology 28: 279-291.
-
(1978)
Journal of Virology
, vol.28
, pp. 279-291
-
-
Schiff, R.D.1
Grandgenett, D.P.2
-
144
-
-
0025366844
-
Human immunodeficiency virus integration protein expressed in Escherichia coli possesses selective DNA cleaving activity
-
Sherman PA & Fyfe JA (1990) Human immunodeficiency virus integration protein expressed in Escherichia coli possesses selective DNA cleaving activity. Proceedings of the National Academy of Sciences, USA 87: 5119-5123.
-
(1990)
Proceedings of the National Academy of Sciences, USA
, vol.87
, pp. 5119-5123
-
-
Sherman, P.A.1
Fyfe, J.A.2
-
145
-
-
0026693410
-
Human immunodeficiency virus type 1 integration protein: DNA sequence requirements for cleaving and joining reactions
-
Sherman PA, Dickson ML & Fyfe JA (1992) Human immunodeficiency virus type 1 integration protein: DNA sequence requirements for cleaving and joining reactions. Journal of Virology 66: 3593-3601.
-
(1992)
Journal of Virology
, vol.66
, pp. 3593-3601
-
-
Sherman, P.A.1
Dickson, M.L.2
Fyfe, J.A.3
-
146
-
-
0024292602
-
Highly preferred targets for retrovirus integration
-
Shih C-C, Stoye JF & Coffin JM (1988) Highly preferred targets for retrovirus integration. Cell 53: 531-538.
-
(1988)
Cell
, vol.53
, pp. 531-538
-
-
Shih, C.-C.1
Stoye, J.F.2
Coffin, J.M.3
-
147
-
-
0028006533
-
Genetic analysis of the human immunodeficiency virus type 1 integrase protein
-
Shin C-C, Taddeo WA, Haseltine WA & Farnet CM (1994) Genetic analysis of the human immunodeficiency virus type 1 integrase protein. Journal of Virology 68: 1633-1642.
-
(1994)
Journal of Virology
, vol.68
, pp. 1633-1642
-
-
Shin, C.-C.1
Taddeo, W.A.2
Haseltine, W.A.3
Farnet, C.M.4
-
148
-
-
0029743107
-
A synthetic peptide from the human immunodeficiency virus type-1 integrase exhibits coiled-coil properties and interferes with the in vitro integration activity of the enzyme. Correlated biochemical and spectroscopic results
-
Sourgen F, Maroun RG, Frere V, Bouziane M, Auclair C, Troalen F & Fermandjian S (1996) A synthetic peptide from the human immunodeficiency virus type-1 integrase exhibits coiled-coil properties and interferes with the in vitro integration activity of the enzyme. Correlated biochemical and spectroscopic results. European Journal of Biochemistry 240: 765-773.
-
(1996)
European Journal of Biochemistry
, vol.240
, pp. 765-773
-
-
Sourgen, F.1
Maroun, R.G.2
Frere, V.3
Bouziane, M.4
Auclair, C.5
Troalen, F.6
Fermandjian, S.7
-
149
-
-
0028846457
-
Erbstatin analogue methyl 2,5-dihydroxycinnamate cross-links proteins and is cytotoxic to normal and neoplastic epithelial cells by a mechanism independent of tyrosine kinase inhibition
-
Stanwell C, Burke TR & Yuspa SH (1995) Erbstatin analogue methyl 2,5-dihydroxycinnamate cross-links proteins and is cytotoxic to normal and neoplastic epithelial cells by a mechanism independent of tyrosine kinase inhibition. Cancer Research 55: 4950-4956.
-
(1995)
Cancer Research
, vol.55
, pp. 4950-4956
-
-
Stanwell, C.1
Burke, T.R.2
Yuspa, S.H.3
-
151
-
-
0029838374
-
Sequence analysis of the human DNA flanking sites of human immunodeficiency virus type 1 integration
-
Stevens SW & Griffith JD (1996) Sequence analysis of the human DNA flanking sites of human immunodeficiency virus type 1 integration. Journal of Virology 70: 6459-6462.
-
(1996)
Journal of Virology
, vol.70
, pp. 6459-6462
-
-
Stevens, S.W.1
Griffith, J.D.2
-
152
-
-
0028131189
-
Identification of factors that govern HIV-1 replication in non-dividing cells
-
Stevenson M (1994) Identification of factors that govern HIV-1 replication in non-dividing cells. AIDS Research and Human Retroviruses 10: S11-S15.
-
(1994)
AIDS Research and Human Retroviruses
, vol.10
-
-
Stevenson, M.1
-
153
-
-
0025238945
-
HIV-1 replication is controlled at the level of T cell activation and proviral integration
-
Stevenson M, Stanwick TL, Dempsey MP & Lamonica CA (1990) HIV-1 replication is controlled at the level of T cell activation and proviral integration. EMBO Journal 9: 1551-1560.
-
(1990)
EMBO Journal
, vol.9
, pp. 1551-1560
-
-
Stevenson, M.1
Stanwick, T.L.2
Dempsey, M.P.3
Lamonica, C.A.4
-
154
-
-
0029861757
-
Reversion of a human immunodeficiency virus type 1 integrase mutant at a second site restores enzyme function and virus infectivity
-
Taddeo B, Carlini F, Verani P & Engelman A (1996) Reversion of a human immunodeficiency virus type 1 integrase mutant at a second site restores enzyme function and virus infectivity. Journal of Virology 12: 8277-8284.
-
(1996)
Journal of Virology
, vol.12
, pp. 8277-8284
-
-
Taddeo, B.1
Carlini, F.2
Verani, P.3
Engelman, A.4
-
155
-
-
0028089732
-
DNA substrate requirements for different activities of the human immunodeficiency virus type 1 integrase protein
-
van den Ent FMI, Vink C & Plasterk RHA (1994) DNA substrate requirements for different activities of the human immunodeficiency virus type 1 integrase protein. Journal of Virology 68: 7825-7832.
-
(1994)
Journal of Virology
, vol.68
, pp. 7825-7832
-
-
Van Den Ent, F.M.I.1
Vink, C.2
Plasterk, R.H.A.3
-
156
-
-
0025775488
-
DNA binding properties of the integrase proteins of human immunodeficiency viruses types 1 and 2
-
van Gent DC, Elgersma Y, Bolk MW, Vink C & Plasterk RHA (1991) DNA binding properties of the integrase proteins of human immunodeficiency viruses types 1 and 2. Nucleic Acids Research 19: 3821-3827.
-
(1991)
Nucleic Acids Research
, vol.19
, pp. 3821-3827
-
-
Van Gent, D.C.1
Elgersma, Y.2
Bolk, M.W.3
Vink, C.4
Plasterk, R.H.A.5
-
159
-
-
0023038804
-
Acceptor sites for retroviral integrations map near DNase I-hypersensitive sites in chromatin
-
Vijaya S, Steffen DL & Robinson HL (1986) Acceptor sites for retroviral integrations map near DNase I-hypersensitive sites in chromatin. Journal of Virology 60: 665-697.
-
(1986)
Journal of Virology
, vol.60
, pp. 665-697
-
-
Vijaya, S.1
Steffen, D.L.2
Robinson, H.L.3
-
160
-
-
0027508068
-
The human immunodeficiency virus integrase protein
-
Vink C & Plasterk RHA (1993) The human immunodeficiency virus integrase protein. Trends in Genetics 9: 433-437.
-
(1993)
Trends in Genetics
, vol.9
, pp. 433-437
-
-
Vink, C.1
Plasterk, R.H.A.2
-
161
-
-
0026348879
-
Site-specific hydrolysis and alcoholysis of human immunodeficiency virus DNA termini mediated by the viral integrase protein
-
Vink C, Yeheskiely E, van der Marel GA, van Boom JH & Plasterk RHA (1991a) Site-specific hydrolysis and alcoholysis of human immunodeficiency virus DNA termini mediated by the viral integrase protein. Nucleic Acids Research 19: 6691-6698.
-
(1991)
Nucleic Acids Research
, vol.19
, pp. 6691-6698
-
-
Vink, C.1
Yeheskiely, E.2
Van Der Marel, G.A.3
Van Boom, J.H.4
Plasterk, R.H.A.5
-
162
-
-
0026095906
-
Human immunodeficiency virus integrase protein requires a subterminal position for its viral DNa recognition sequence for efficient cleavage
-
Vink C, van Gent DC, Elgersma Y & Plasterk RHA (1991b) Human immunodeficiency virus integrase protein requires a subterminal position for its viral DNA recognition sequence for efficient cleavage. Journal of Virology 65: 4636-4644.
-
(1991)
Journal of Virology
, vol.65
, pp. 4636-4644
-
-
Vink, C.1
Van Gent, D.C.2
Elgersma, Y.3
Plasterk, R.H.A.4
-
163
-
-
0027210608
-
Identification of the catalytic and DNA-binding region of the human immunodeficiency virus type I integrase protein
-
Vink C, Oude Groeninger AAM & Plasterk RHA (1993) Identification of the catalytic and DNA-binding region of the human immunodeficiency virus type I integrase protein. Nucleic Acids Research 21: 1419-1425.
-
(1993)
Nucleic Acids Research
, vol.21
, pp. 1419-1425
-
-
Vink, C.1
Oude Groeninger, A.A.M.2
Plasterk, R.H.A.3
-
164
-
-
0028125329
-
Formation of a stable complex between the human immunodeficiency virus integrase protein and viral DNA
-
Vink C, Lutzke RAP & Plasterk RHA (1994a) Formation of a stable complex between the human immunodeficiency virus integrase protein and viral DNA. Nucleic Acids Research 22: 4103-4110.
-
(1994)
Nucleic Acids Research
, vol.22
, pp. 4103-4110
-
-
Vink, C.1
Lutzke, R.A.P.2
Plasterk, R.H.A.3
-
165
-
-
0028238134
-
A high-throughput, non-radioactive microtiter plate assay for activity of the human immunodeficiency virus integrase protein
-
Vink C, Banks M, Bethell R & Plasterk RHA (1994b) A high-throughput, non-radioactive microtiter plate assay for activity of the human immunodeficiency virus integrase protein. Nucleic Acids Research 22: 2176-2177.
-
(1994)
Nucleic Acids Research
, vol.22
, pp. 2176-2177
-
-
Vink, C.1
Banks, M.2
Bethell, R.3
Plasterk, R.H.A.4
-
166
-
-
0028234528
-
The nuclear localization signal of the matrix protein of human immunodeficiency virus type 1 allow the establishment of infection in macrophages and quiescent T lymphocytes
-
von Schwedler U, Kornbluth RS & Trono D (1994) The nuclear localization signal of the matrix protein of human immunodeficiency virus type 1 allow the establishment of infection in macrophages and quiescent T lymphocytes. Proceedings of the National Academy of Sciences, USA 91: 6992-6996.
-
(1994)
Proceedings of the National Academy of Sciences, USA
, vol.91
, pp. 6992-6996
-
-
Von Schwedler, U.1
Kornbluth, R.S.2
Trono, D.3
-
167
-
-
0028784884
-
Assembly and catalytic properties of retrovirus integrase-DNA complexes capable of efficiently performing concerted integration
-
Vora AC & Grandgenett DP (1995) Assembly and catalytic properties of retrovirus integrase-DNA complexes capable of efficiently performing concerted integration. Journal of Virology 69: 7483-7488.
-
(1995)
Journal of Virology
, vol.69
, pp. 7483-7488
-
-
Vora, A.C.1
Grandgenett, D.P.2
-
168
-
-
10144228410
-
Purification and biochemical heterogeneity of the mammalian SWI-SNF complex
-
Wang W, Cote J, Xue Y, Zhou S, Khavari PA, Biggar SR, Muchardt C, Kalpana GV, Goff SP, Yaniv M, Workman JL & Crabtree GR (1996) Purification and biochemical heterogeneity of the mammalian SWI-SNF complex. EMBO Journal 15: 5370-5382.
-
(1996)
EMBO Journal
, vol.15
, pp. 5370-5382
-
-
Wang, W.1
Cote, J.2
Xue, Y.3
Zhou, S.4
Khavari, P.A.5
Biggar, S.R.6
Muchardt, C.7
Kalpana, G.V.8
Goff, S.P.9
Yaniv, M.10
Workman, J.L.11
Crabtree, G.R.12
-
169
-
-
0028924020
-
Human immunodeficiency virus type 1 integrase: Effects of mutations on viral ability to integrate, direct viral gene expression from unintegrated viral DNA templates, and sustain viral propagation in primary cells
-
Wiskerchen M & Muesing MA (1995a) Human immunodeficiency virus type 1 integrase: effects of mutations on viral ability to integrate, direct viral gene expression from unintegrated viral DNA templates, and sustain viral propagation in primary cells. Journal of Virology 69: 376-386.
-
(1995)
Journal of Virology
, vol.69
, pp. 376-386
-
-
Wiskerchen, M.1
Muesing, M.A.2
-
170
-
-
0028936208
-
Identification and characterization of a temperature-sensitive mutant of human immunodeficiency virus type 1 by alanine scanning mutagenesis of the integrase gene
-
Wiskerchen M & Muesing MA (1995b) Identification and characterization of a temperature-sensitive mutant of human immunodeficiency virus type 1 by alanine scanning mutagenesis of the integrase gene. Journal of Virology 69: 597-601.
-
(1995)
Journal of Virology
, vol.69
, pp. 597-601
-
-
Wiskerchen, M.1
Muesing, M.A.2
-
173
-
-
0027205243
-
Characterization of a DNa binding domain in the C-terminus of HIV-1 integrase by deletion mutagenesis
-
Woerner AM & Marcus-Sekura CJ (1993) Characterization of a DNA binding domain in the C-terminus of HIV-1 integrase by deletion mutagenesis. Nucleic Acids Research 21: 3507-3511.
-
(1993)
Nucleic Acids Research
, vol.21
, pp. 3507-3511
-
-
Woerner, A.M.1
Marcus-Sekura, C.J.2
-
174
-
-
0029643952
-
Recombining the structures of HIV integrase, RuvC and RNase H
-
Yang W & Steitz TA (1995) Recombining the structures of HIV integrase, RuvC and RNase H. Current Biology 3: 131-134.
-
(1995)
Current Biology
, vol.3
, pp. 131-134
-
-
Yang, W.1
Steitz, T.A.2
-
175
-
-
0028908038
-
Different roles of bases within the integration signal sequence of human immunodeficiency virus type 1 in vitro
-
Yoshinaga T & Fujiwara T (1995) Different roles of bases within the integration signal sequence of human immunodeficiency virus type 1 in vitro. Journal of Virology 69: 3233-3236.
-
(1995)
Journal of Virology
, vol.69
, pp. 3233-3236
-
-
Yoshinaga, T.1
Fujiwara, T.2
-
176
-
-
0028087997
-
Detection and characterization of a functional complex of human immunodeficiency virus type 1 intergrase and its substance by UV cross-linking
-
Yoshinaga T, Kimura-Ohtani Y & Fujiwara T (1994) Detection and characterization of a functional complex of human immunodeficiency virus type 1 intergrase and its substance by UV cross-linking. Journal of Virology 68: 5690-5697.
-
(1994)
Journal of Virology
, vol.68
, pp. 5690-5697
-
-
Yoshinaga, T.1
Kimura-Ohtani, Y.2
Fujiwara, T.3
-
177
-
-
0031013534
-
Coumarin-based inhibitors of HIV integrase
-
Zhao H, Neamati N, Hong H, Mazumder A, Wang S, Sunder S, Milne GWA, Pommier Y & Burke Jr TR (1996) Coumarin-based inhibitors of HIV integrase. Journal of Medicinal Chemistry 40: 242-249.
-
(1996)
Journal of Medicinal Chemistry
, vol.40
, pp. 242-249
-
-
Zhao, H.1
Neamati, N.2
Hong, H.3
Mazumder, A.4
Wang, S.5
Sunder, S.6
Milne, G.W.A.7
Pommier, Y.8
Burke Jr., T.R.9
-
178
-
-
0030946320
-
Hydrazide-containing inhibitors of HIV-1 integrase
-
in press
-
Zhao H, Neamati N, Sunder S, Hong H, Wang S, Milne GWA, Pommier Y & Burke T (1997a) Hydrazide-containing inhibitors of HIV-1 integrase. Journal of Medicinal Chemistry (in press).
-
(1997)
Journal of Medicinal Chemistry
-
-
Zhao, H.1
Neamati, N.2
Sunder, S.3
Hong, H.4
Wang, S.5
Milne, G.W.A.6
Pommier, Y.7
Burke, T.8
-
179
-
-
0030936836
-
Arylamide inhibitors of HIV-1 integrase
-
Zhao H, Neamati N, Mazumder A, Sunder S, Pommier Y & Burke T (1997b) Arylamide inhibitors of HIV-1 integrase. Journal of Medicinal Chemistry 40: 1186-1194.
-
(1997)
Journal of Medicinal Chemistry
, vol.40
, pp. 1186-1194
-
-
Zhao, H.1
Neamati, N.2
Mazumder, A.3
Sunder, S.4
Pommier, Y.5
Burke, T.6
-
180
-
-
0030478950
-
Zinc folds the N-terminal domain of HIV-1 integrase, promotes multimerization, and enhances catalytic activity
-
Zheng R, Jenkins TM & Craigie R (1996) Zinc folds the N-terminal domain of HIV-1 integrase, promotes multimerization, and enhances catalytic activity. Proceedings of the National Academy of Sciences, USA 93: 13659-13664.
-
(1996)
Proceedings of the National Academy of Sciences, USA
, vol.93
, pp. 13659-13664
-
-
Zheng, R.1
Jenkins, T.M.2
Craigie, R.3
|