메뉴 건너뛰기




Volumn 39, Issue 13, 1996, Pages 2472-2481

Antiretroviral agents as inhibitors of both human immunodeficiency virus type 1 integrase and protease

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYCOUMARIN; ANTIVIRUS AGENT; DNA TOPOISOMERASE; INTEGRASE; NSC 117027; NSC 158393; PROTEINASE INHIBITOR; UNCLASSIFIED DRUG; VIRUS DNA; VIRUS ENZYME;

EID: 15844424316     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm960074e     Document Type: Article
Times cited : (174)

References (29)
  • 1
    • 0029011730 scopus 로고
    • Toward improved anti-HIV chemotherapy: Therapeutic strategies for intervention with HIV infections
    • De Clercq, E. Toward improved anti-HIV chemotherapy: therapeutic strategies for intervention with HIV infections. J. Med. Chem. 1995, 38, 2491-2517.
    • (1995) J. Med. Chem. , vol.38 , pp. 2491-2517
    • De Clercq, E.1
  • 2
    • 0028820595 scopus 로고
    • Effects of Tyrphostins, Protein Kinase Inhibitors, on Human Immunodeficiency Virus Type 1 Integrase
    • Mazumder, A.; Gazit, A.; Levitzki, A.; Nicklaus, M.; Yung, J.; Kohlhagen, G.; Pommier, Y. Effects of Tyrphostins, Protein Kinase Inhibitors, on Human Immunodeficiency Virus Type 1 Integrase. Biochemistry 1995, 34, 15111-15122.
    • (1995) Biochemistry , vol.34 , pp. 15111-15122
    • Mazumder, A.1    Gazit, A.2    Levitzki, A.3    Nicklaus, M.4    Yung, J.5    Kohlhagen, G.6    Pommier, Y.7
  • 4
    • 0027222149 scopus 로고
    • Inhibitory effect of the polyanionic drug suramin on the in vitro HIV DNA integration reaction
    • Carteau, S.; Mouscadet, J. F.; Goulaouic, H.; Subra, F.; Auclair, C. Inhibitory effect of the polyanionic drug suramin on the in vitro HIV DNA integration reaction. Arch. Biochem. Biophys. 1993, 305, 606-610.
    • (1993) Arch. Biochem. Biophys. , vol.305 , pp. 606-610
    • Carteau, S.1    Mouscadet, J.F.2    Goulaouic, H.3    Subra, F.4    Auclair, C.5
  • 5
    • 0028242724 scopus 로고
    • Inhibition of human immunodeficiency virus type 1 integrase by 3′-azido-3′-deoxythymidylate
    • Mazumder, A.; Cooney, D.; Agbaria, R.; Gupta, M.; Pommier, Y. Inhibition of human immunodeficiency virus type 1 integrase by 3′-azido-3′-deoxythymidylate Proc. Natl. Acad. Sci. U.S.A. 1994, 91, 5771-5775.
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 5771-5775
    • Mazumder, A.1    Cooney, D.2    Agbaria, R.3    Gupta, M.4    Pommier, Y.5
  • 7
    • 0028924020 scopus 로고
    • Human immunodeficiency virus type 1 integrase: Effects of mutations on viral ability to integrate, direct viral gene expression from unintegrated viral DNA templates, and sustain viral propagation in primary cells
    • Wiskerchen, M. A.; Muesing, M. A. Human immunodeficiency virus type 1 integrase: effects of mutations on viral ability to integrate, direct viral gene expression from unintegrated viral DNA templates, and sustain viral propagation in primary cells. J. Virol. 1995, 69, 376-386.
    • (1995) J. Virol. , vol.69 , pp. 376-386
    • Wiskerchen, M.A.1    Muesing, M.A.2
  • 8
    • 0028915128 scopus 로고
    • Multiple effects of mutations in human immunodeficiency virus type 1 integrase on viral replication
    • Engelman, A.; Englund, G.; Orenstein, J. M.; Martin, M. A.; Craigie, R. Multiple effects of mutations in human immunodeficiency virus type 1 integrase on viral replication. J. Virol. 1995, 69, 2729-2736.
    • (1995) J. Virol. , vol.69 , pp. 2729-2736
    • Engelman, A.1    Englund, G.2    Orenstein, J.M.3    Martin, M.A.4    Craigie, R.5
  • 9
    • 0025011051 scopus 로고
    • The avian retroviral in protein is both necessary and sufficient for integrative recombination in vitro
    • Katz, R. A.; Merkel, G.; Kulkosky, J.; Leis, J.; Skalka, A. M. The avian retroviral IN protein is both necessary and sufficient for integrative recombination in vitro. Cell 1990, 63, 87-95.
    • (1990) Cell , vol.63 , pp. 87-95
    • Katz, R.A.1    Merkel, G.2    Kulkosky, J.3    Leis, J.4    Skalka, A.M.5
  • 10
    • 0025031786 scopus 로고
    • The in protein of Moloney murine leukemia virus processes the viral DNA ends and accomplishes their integration in vitro
    • Craigie, R.; Fujiwara, T.; Bushman, F. The IN protein of Moloney murine leukemia virus processes the viral DNA ends and accomplishes their integration in vitro. Cell 1990, 62, 829-837.
    • (1990) Cell , vol.62 , pp. 829-837
    • Craigie, R.1    Fujiwara, T.2    Bushman, F.3
  • 12
    • 0027508068 scopus 로고
    • The human immunodeficiency virus integrase protein
    • Vink, C.; Plasterk, R. H. A. The human immunodeficiency virus integrase protein. Trends Genet. 1993, 9, 433-437.
    • (1993) Trends Genet. , vol.9 , pp. 433-437
    • Vink, C.1    Plasterk, R.H.A.2
  • 13
    • 0026330796 scopus 로고
    • HIV-1 DNA integration: Mechanism of viral DNA cleavage and DNA strand transfer
    • Engelman, A.; Mizuuchi, K.; Craigie, R. HIV-1 DNA integration: mechanism of viral DNA cleavage and DNA strand transfer. Cell 1991, 67, 1211-21.
    • (1991) Cell , vol.67 , pp. 1211-1221
    • Engelman, A.1    Mizuuchi, K.2    Craigie, R.3
  • 14
    • 0027456715 scopus 로고
    • Domains of the integrase protein of human immunodeficiency virus type 1 responsible for polynucleotidyl transfer and zinc binding
    • Bushman, F. D.; Engelman, A.; Palmer, I.; Wingfield, P.; Craigie, R. Domains of the integrase protein of human immunodeficiency virus type 1 responsible for polynucleotidyl transfer and zinc binding. Proc. Natl. Acad. Sci. U.S.A. 1993, 90, 3428-3432.
    • (1993) Proc. Natl. Acad. Sci. U.S.A. , vol.90 , pp. 3428-3432
    • Bushman, F.D.1    Engelman, A.2    Palmer, I.3    Wingfield, P.4    Craigie, R.5
  • 15
    • 0026549933 scopus 로고
    • Reversal of integration and DNA splicing mediated by integrase of human immunodeficiency virus
    • Chow, S. A.; Vincent, K. A.; Ellison, V.; Brown, P. O. Reversal of integration and DNA splicing mediated by integrase of human immunodeficiency virus. Science 1992, 255, 723-726.
    • (1992) Science , vol.255 , pp. 723-726
    • Chow, S.A.1    Vincent, K.A.2    Ellison, V.3    Brown, P.O.4
  • 16
    • 0029081258 scopus 로고
    • Interaction of an alkylating camptothecin derivative with a DNA base at topoisomerase I-DNA cleavage sites
    • Pommier, Y.; Kohlhagen, G.; Kohn, K. W.; Leteurtre, F.; Wani, M. C.; Wall, M. E. Interaction of an alkylating camptothecin derivative with a DNA base at topoisomerase I-DNA cleavage sites. Proc. Natl. Acad. Sci. U.S.A. 1995, 92, 8861-8865.
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 8861-8865
    • Pommier, Y.1    Kohlhagen, G.2    Kohn, K.W.3    Leteurtre, F.4    Wani, M.C.5    Wall, M.E.6
  • 17
    • 0026348879 scopus 로고
    • Site-specific hydrolysis and alcoholysis of human immunodeficiency virus DNA termini mediated by the viral integrase protein
    • Vink, C.; Yeheskiely, E.; van der Marel, G. A.; van Boom, J. H.; Plasterk, R. H. Site-specific hydrolysis and alcoholysis of human immunodeficiency virus DNA termini mediated by the viral integrase protein. Nucl. Acids Res. 1991, 19, 6691-8.
    • (1991) Nucl. Acids Res. , vol.19 , pp. 6691-6698
    • Vink, C.1    Yeheskiely, E.2    Van Der Marel, G.A.3    Van Boom, J.H.4    Plasterk, R.H.5
  • 18
    • 0026719238 scopus 로고
    • Residues critical for retroviral integrative recombination in a region that is highly conserved among retroviral/retrotransposon integrases and bacterial insertion sequence transposases
    • Kulkosky, J.; Jones, K. S.; Katz, R. A.; Mack, J. P.; Skalka, A. M. Residues critical for retroviral integrative recombination in a region that is highly conserved among retroviral/retrotransposon integrases and bacterial insertion sequence transposases. Mol. Cell Biol. 1992, 12, 2331-2338.
    • (1992) Mol. Cell Biol. , vol.12 , pp. 2331-2338
    • Kulkosky, J.1    Jones, K.S.2    Katz, R.A.3    Mack, J.P.4    Skalka, A.M.5
  • 19
    • 0028067324 scopus 로고
    • The core and carboxyl-terminal domains of the integrase protein of human immunodeficiency virus type 1 each contribute to nonspecific DNA binding
    • Engelman, A.; Hickman, A. B.; Craigie, R. The core and carboxyl-terminal domains of the integrase protein of human immunodeficiency virus type 1 each contribute to nonspecific DNA binding. J. Virol. 1994, 68, 5911-5917.
    • (1994) J. Virol. , vol.68 , pp. 5911-5917
    • Engelman, A.1    Hickman, A.B.2    Craigie, R.3
  • 22
    • 0026649557 scopus 로고
    • Identification of conserved amino acid residues critical for human immunodeficiency virus type 1 integrase function in vitro
    • Engelman, A.; Craigie, R. Identification of conserved amino acid residues critical for human immunodeficiency virus type 1 integrase function in vitro. J. Virol. 1992, 66, 6361-6369.
    • (1992) J. Virol. , vol.66 , pp. 6361-6369
    • Engelman, A.1    Craigie, R.2
  • 23
    • 0026019625 scopus 로고
    • Structural basis for the 3′-5′ exonuclease activity of Escherichia coli DNA polymerase I: A two metal ion mechanism
    • Beese, L. S.; Steitz, T. A. Structural basis for the 3′-5′ exonuclease activity of Escherichia coli DNA polymerase I: a two metal ion mechanism. EMBO J. 1991, 10, 25-33.
    • (1991) EMBO J. , vol.10 , pp. 25-33
    • Beese, L.S.1    Steitz, T.A.2
  • 24
    • 0028070994 scopus 로고
    • Inhibition of HIV-1 integrase by flavones, caffeic acid phenethyl ester (CAPE) and related compounds
    • Fesen, M.; Pommier, Y.; Leteurtre, F.; Hiroguchi, S.; Yung, J.; Kohn, K. W. Inhibition of HIV-1 integrase by flavones, caffeic acid phenethyl ester (CAPE) and related compounds. Biochem. Pharmacol. 1994, 48, 595-608.
    • (1994) Biochem. Pharmacol. , vol.48 , pp. 595-608
    • Fesen, M.1    Pommier, Y.2    Leteurtre, F.3    Hiroguchi, S.4    Yung, J.5    Kohn, K.W.6
  • 26
    • 0029062402 scopus 로고
    • Inhibition of human immunodeficiency virus type 1 integrase by a hydrophobic cation: The phenanthroline-cuprous complex
    • Mazumder, A.; Gupta, M.; Perrin, D. M.; Sigman, D. S.; Rabinovitz, M.; Pommier, Y. Inhibition of human immunodeficiency virus type 1 integrase by a hydrophobic cation: the phenanthroline-cuprous complex. AIDS Res. Hum. Retroviruses 1995, 11, 115-125.
    • (1995) AIDS Res. Hum. Retroviruses , vol.11 , pp. 115-125
    • Mazumder, A.1    Gupta, M.2    Perrin, D.M.3    Sigman, D.S.4    Rabinovitz, M.5    Pommier, Y.6
  • 28
    • 0027430147 scopus 로고
    • Inhibition of the protease of human immunodeficiency virus blocks replication and infectivity of the virus in chronically infected macrophages
    • Perno, C. F.; Bergamini, A.; Pesce, C. D.; Milanese, G.; Capozzi, M.; Aquaro, S.; Thaisrivangs, S.; et al. Inhibition of the protease of human immunodeficiency virus blocks replication and infectivity of the virus in chronically infected macrophages. J. Infect. Dis. 1993, 168, 1148-1156.
    • (1993) J. Infect. Dis. , vol.168 , pp. 1148-1156
    • Perno, C.F.1    Bergamini, A.2    Pesce, C.D.3    Milanese, G.4    Capozzi, M.5    Aquaro, S.6    Thaisrivangs, S.7
  • 29
    • 0024578841 scopus 로고
    • New soluble-formazan assay for HIV-1 cytopathic effects: Application to high-flux screening of synthetic and natural products for AIDS-antiviral activity
    • Weislow, O. S.; Kiser, R.; Fine, D. L.; Bader, J.; Shoemaker, R. H.; Boyd, M. R. New soluble-formazan assay for HIV-1 cytopathic effects: Application to high-flux screening of synthetic and natural products for AIDS-antiviral activity. J. Natl. Cancer Inst. 1989, 81, 577-586.
    • (1989) J. Natl. Cancer Inst. , vol.81 , pp. 577-586
    • Weislow, O.S.1    Kiser, R.2    Fine, D.L.3    Bader, J.4    Shoemaker, R.H.5    Boyd, M.R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.