Increased cytosol Ca2+ and type 1 programmed cell death in Bcl-2-positive U937 but not in Bcl-2-negative PC-3 and Panc-1 cells induced by the 5-lipoxygenase inhibitor MK 886

Prostaglandins Leukotrienes and Essential Fatty Acids

Volumn 66, Issue 4, 2002, Pages 443-452

  Anderson, K M ^a,b   Alrefai, W A ^a,c,d   Dudeja, P K ^c,d   Jadko, S ^a,b   Bonomi, P ^a   Hu, Y ^a   Ou, D ^c,d   Harris, J E ^a  

^a Section of Medical Oncology   (United States)

^b Department of Biochemistry ^*  (United States)

^c UNIVERSITY OF ILLINOIS   (United States)

^d JESSE BROWN VA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 [3 TERT BUTYLTHIO 1 (4 CHLOROBENZYL) 5 ISOPROPYL 2 INDOLYL] 2,2 DIMETHYLPROPIONIC ACID; CALCIUM ION; ION CHANNEL; LIPOXYGENASE INHIBITOR; PROTEIN BCL 2; SC 41661A; UNCLASSIFIED DRUG; ARACHIDONATE 5 LIPOXYGENASE; CALCIUM; FLUORESCENT DYE; INDOLE DERIVATIVE; MESSENGER RNA;

APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CANCER CELL CULTURE; CELL MATURATION; CELL PROLIFERATION; CELL STRAIN HL 60; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENZYME ACTIVITY; FLUORESCENCE; HUMAN; HUMAN CELL; IONIZATION; MITOCHONDRIAL MEMBRANE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN FUNCTION; REDUCTION; RNA SYNTHESIS; CALCIUM SIGNALING; CELL CULTURE; CELL MEMBRANE POTENTIAL; CELL STRAIN U937; CYTOSOL; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; METABOLISM; MITOCHONDRION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

APOPTOSIS; ARACHIDONATE 5-LIPOXYGENASE; CALCIUM; CALCIUM SIGNALING; CYTOSOL; FLUORESCENT DYES; HL-60 CELLS; HUMANS; INDOLES; LIPOXYGENASE INHIBITORS; MEMBRANE POTENTIALS; MITOCHONDRIA; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS C-BCL-2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR CELLS, CULTURED; U937 CELLS;

EID: 0035989488     PISSN: 09523278     EISSN: None     Source Type: Journal    
DOI: 10.1054/plef.2001.0372     Document Type: Article

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