An in vivo inhibitor of 5-lipoxygenase, MK886, at micromolar concentration induces apoptosis in U937 and CML cells

Anticancer Research

Volumn 16, Issue 5 A, 1996, Pages 2589-2599

  Anderson, K M ^a   Seed, T ^b   Jajeh, A ^c   Dudeja, P ^d   Byun, T ^a   Meng, J ^a   Ou, D ^d   Bonomi, P ^a   Harris, J E ^a  

^a RUSH MEDICAL COLLEGE   (United States)

^b ARGONNE NATIONAL LABORATORY   (United States)

^c Jr Hospital of Cook County   (United States)

^d UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Experimental apoptosis; Leukemia; Lipoxygenase inhibitors

Indexed keywords

3 [3 TERT BUTYLTHIO 1 (4 CHLOROBENZYL) 5 ISOPROPYL 2 INDOLYL] 2,2 DIMETHYLPROPIONIC ACID; CALCIUM ION; LIPOXYGENASE INHIBITOR;

APOPTOSIS; ARACHIDONIC ACID METABOLISM; ARTICLE; CALCIUM CELL LEVEL; CELL CULTURE; CELL PROLIFERATION; CHRONIC MYELOID LEUKEMIA; CONTROLLED STUDY; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

APOPTOSIS; ARACHIDONATE 5-LIPOXYGENASE; CALCIUM; CELL COUNT; CELL DIVISION; DIMETHYL SULFOXIDE; DNA, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; FLOW CYTOMETRY; G2 PHASE; HUMANS; INDOLES; LEUKEMIA, MYELOID, CHRONIC; MITOSIS; TUMOR CELLS, CULTURED;

EID: 0029911297     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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