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Volumn 40, Issue 34, 2001, Pages 10150-10160

Phenylalanine and tryptophan scanning mutagenesis of CYP3A4 substrate recognition site residues and effect on substrate oxidation and cooperativity

(6) Domanski, T L a He, Y A a Khan, K K a Roussel, F a Wang, Q a Halpert, J R a

a University of Texas Medical Branch School of Medicine (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SIGMOIDAL KINETICS;

HYDROXYLATION; MUTAGENESIS; OXIDATION; SUBSTRATES;

BIOCHEMISTRY;

ALPHA NAPHTHOFLAVONE; ANDROSTENEDIONE; COUMARIN DERIVATIVE; CYTOCHROME P450 3A4; PHENYLALANINE; PROGESTERONE; TESTOSTERONE; TRYPTOPHAN;

ARTICLE; COOPERATION; CORRELATION FUNCTION; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; HYDROXYLATION; KINETICS; MODEL; MUTAGENESIS; OXIDATION; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; BASE SEQUENCE; BINDING SITES; CLONING, MOLECULAR; CYTOCHROME P-450 ENZYME SYSTEM; DNA PRIMERS; ESCHERICHIA COLI; HUMANS; KINETICS; LIVER; MIXED FUNCTION OXYGENASES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PHENYLALANINE; PROGESTERONE; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY; TRYPTOPHAN;

EID: 0035964178 PISSN: 00062960 EISSN: None Source Type: Journal
DOI: 10.1021/bi010758a Document Type: Article

Times cited : (130)

References (44)

1
- 0033569516
- (1999) Science , vol.286 , pp. 487-491
- Evans, W.E.¹ Relling, M.V.²

2
- 0029584276
- (1995) Toxicology , vol.104 , pp. 1-8
- Li, A.P.¹ Kaminski, D.L.² Rasmussen, A.³

3
- 0028129646
- (1994) Drug Metab. Dispos. , vol.22 , pp. 688-692
- Buters, J.T.M.¹ Korzekwa, K.R.² Kunze, K.L.³ Omata, Y.⁴ Hardwick, J.P.⁵ Gonzalez, F.J.⁶

4
- 0029876042
- (1996) Int. J. Clin. Pharmacol. Ther. , vol.34 , pp. 139-151
- Fuhr, U.¹ Weiss, M.² Kroemer, H.K.³ Neugebauer, G.⁴ Rameis, H.⁵ Weber, W.⁶ Woodcock, B.G.⁷

5
- 0028986147
- (1995) Chem. Res. Toxicol. , vol.8 , pp. 218-225
- Ueng, Y.¹ Shimada, T.² Yamazaki, H.³ Guengerich, F.P.⁴

6
- 0031028518
- (1997) Biochemistry , vol.36 , pp. 370-381
- Ueng, Y.F.¹ Kuwabara, T.² Chun, Y.J.³ Guengerich, F.P.⁴

7
- 0023273657
- (1987) Biochem. Pharmacol. , vol.36 , pp. 1251-1260
- Grant, D.M.¹ Campbell, M.E.² Tang, B.K.³ Kalow, W.⁴

8
- 0028300816
- (1994) Biochem. Pharmacol. , vol.47 , pp. 1969-1979
- Kerr, B.M.¹ Thummel, K.E.² Wurden, C.J.³ Klein, S.M.⁴ Kroetz, D.L.⁵ Gonzalez, F.J.⁶ Levy, R.H.⁷

9
- 0023949862
- (1988) Mol. Pharmacol. , vol.33 , pp. 493-499
- Schwab, G.E.¹ Raucy, J.L.² Johnson, E.F.³

10
- 0027935778
- (1994) Br. J. Clin. Pharmacol. , vol.38 , pp. 131-137
- Andersson, T.¹ Miners, J.O.² Veronese, M.E.³ Birkett, D.J.⁴

11
- 0033564235
- (1999) Biochem. J. , vol.340 , pp. 845-853
- Shou, M.¹ Mei, Q.² Ettore, M.W.³ Dai, R.⁴ Baillie, T.A.⁵ Rushmore, T.H.⁶

12
- 0032499691
- (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , pp. 6636-6641
- Harlow, G.R.¹ Halpert, J.R.²

13
- 0019826389
- (1981) J. Biol. Chem. , vol.256 , pp. 6829-6836
- Huang, M.T.¹ Chang, R.L.² Fortner, J.G.³ Conney, A.H.⁴

14
- 0003965144
- (1984) J. Pharmacol. Exp. Ther. , vol.277 , pp. 287-291
- Lasker, J.M.¹ Huang, M.T.² Conney, A.H.³

15
- 0019955123
- (1982) Science , vol.216 , pp. 1419-1421
- Lasker, J.M.¹ Huang, M.T.² Conney, A.H.³

16
- 0033048695
- (1999) Chem. Res. Toxicol. , vol.12 , pp. 192-199
- Tang, W.¹ Stearns, R.A.² Wang, R.W.³ Chiu, S.-H.L.⁴ Baillie, T.A.⁵

17
- 0032732349
- (1999) J. Pharmacol. Exp. Ther. , vol.291 , pp. 1068-1074
- Tang, W.¹ Stearns, R.A.² Kwei, G.L.³ Iliff, S.A.⁴ Miller, R.R.⁵ Egan, M.A.⁶ Yu, N.X.⁷ Dean, D.C.⁸ Kumar, S.⁹ Shou, M.¹⁰ Lin, J.H.¹¹ Baillie, T.A.¹²

18
- 0028307539
- (1994) Biochemistry , vol.33 , pp. 6450-6455
- Shou, M.¹ Grogan, J.² Mancewica, J.A.³ Krausz, K.W.⁴ Gonzalez, F.J.⁵ Gelboin, H.V.⁶ Korzekwa, K.R.⁷

19
- 0034108229
- (2000) J. Pharmacol. Exp. Ther. , vol.293 , pp. 585-591
- Domanski, T.L.¹ He, Y.A.² Harlow, G.R.³ Halpert, J.R.⁴

20
- 0034705191
- (2000) Biochemistry , vol.39 , pp. 5929-5939
- Hosea, N.A.¹ Miller, G.P.² Guengerich, F.P.³

21
- 0031022331
- (1997) J. Biol. Chem. , vol.272 , pp. 3149-3152
- Koley, A.P.¹ Buters, J.T.M.² Robinson, R.C.³ Markowitz, A.⁴ Friedman, F.K.⁵

22
- 0000574406
- (1998) Biochemistry , vol.37 , pp. 4137-4147
- Korzekwa, K.R.¹ Krishnamachary, N.² Shou, M.³ Ogai, A.⁴ Parise, R.A.⁵ Rettie, A.E.⁶ Gonzalez, F.J.⁷ Tracy, T.S.⁸

23
- 0035910579
- (2001) J. Biol. Chem. , vol.276 , pp. 2256-2262
- Shou, M.¹ Dais, R.² Cui, D.³ Korzekwa, K.R.⁴ Baillie, T.A.⁵ Rushmore, T.H.⁶

24
- 0031005752
- (1997) Drug Metab. Dispos. , vol.25 , pp. 502-507
- Wang, R.W.¹ Newton, D.J.² Scheri, T.D.³ Lu, A.Y.H.⁴

25
- 0034093628
- (2000) Drug Metab. Dispos. , vol.28 , pp. 360-366
- Wang, R.W.¹ Newton, D.J.² Atkins, W.M.³ Lu, A.Y.H.⁴

26
- 0003971378
- Montpellier, France
- (1998) 12th International Symposium on Microsomes and Drug Oxidations , pp. 136
- Kenworthy, K.E.¹ Clarke, S.E.² Andrews, J.³ Houston, J.B.⁴

27
- 0034724310
- (2000) Proc. Natl. Acad. Sci. U.S.A. , vol.97 , pp. 3050-3055
- Cupp-Vickery, J.¹ Anderson, R.² Hatziris, Z.³

28
- 0031824305
- (1998) Arch. Biochem. Biophys. , vol.350 , pp. 223-232
- Domanski, T.L.¹ Liu, J.² Harlow, G.R.³ Halpert, J.R.⁴

29
- 0031041652
- (1997) J. Biol. Chem. , vol.272 , pp. 5396-5402
- Harlow, G.R.¹ Halpert, J.R.²

30
- 0000227103
- (1997) Biochemistry , vol.36 , pp. 8831-8839
- He, Y.A.¹ He, Y.Q.² Szklarz, G.D.³ Halpert, J.R.⁴

31
- 0034650844
- (1999) Arch. Biochem. Biophys. , vol.373 , pp. 335-345
- Khan, K.K.¹ Halpert, J.R.²

32
- 0034652348
- (1999) Arch. Biochem. Biophys. , vol.374 , pp. 269-278
- Roussel, F.¹ Khan, K.K.² Halpert, J.R.³

33
- 0032497361
- (1998) Biochemistry , vol.37 , pp. 12536-12545
- Wang, H.¹ Dick, R.² Yin, H.³ Licad-Coles, E.⁴ Kroetz, D.L.⁵ Szklarz, G.D.⁶ Harlow, G.R.⁷ Halpert, J.R.⁸ Correia, M.A.⁹

34
- 0033970047
- (2000) Mol. Cell , vol.5 , pp. 121-131
- Williams, P.A.¹ Cosme, J.² Sridhar, V.³ Johnson, E.F.⁴ McRee, D.E.⁵

35
- 0003763518
- in press
- (2001) Curr. Drug Metab.
- Domanski, T.L.¹ Halpert, J.R.²

36
- 0032803537
- (1999) J. Pharmacol. Exp. Ther. , vol.290 , pp. 1141-1147
- Domanski, T.L.¹ Schultz, K.M.² Roussel, F.³ Stevens, J.C.⁴ Halpert, J.R.⁵

37
- 0027507429
- (1993) BioTechniques , vol.14 , pp. 256-265
- Stemmer, W.P.¹ Morris, S.K.² Wilson, B.S.³

38
- 0032765801
- (1999) J. Pharmacol. Exp. Ther. , vol.290 , pp. 594-602
- Stevens, J.C.¹ Domanski, T.L.² Harlow, G.R.³ White, R.B.⁴ Orton, E.⁵ Halpert, J.R.⁶

39
- 0027969978
- (1994) Arch. Biochem. Biophys. , vol.314 , pp. 367-375
- John, G.H.¹ Hasler, J.A.² He, Y.³ Halpert, J.R.⁴

40
- 0033664783
- (2000) Drug Metab. Dispos. , vol.28 , pp. 1440-1448
- Stresser, D.M.¹ Blanchard, A.P.² Turner, S.D.³ Erve, J.C.⁴ Dandeneau, A.A.⁵ Miller, V.P.⁶ Crespi, C.L.⁷

41
- 0031743851
- (1998) Int. J. Clin. Pharmacol. Ther. , vol.36 , pp. 642-651
- Ekins, S.¹ Ring, B.J.² Binkley, S.N.³ Hall, S.D.⁴ Wrighton, S.A.⁵

42
- 0032735988
- (1999) Br. J. Clin. Pharmacol. , vol.48 , pp. 716-727
- Kenworthy, K.E.¹ Bloomer, J.C.² Clarke, S.E.³ Houston, J.B.⁴

43
- 0001683314
- (Ortiz de Montellano, P. R., Ed.) Plenum Press, New York
- (1995) Cytochrome P450 , pp. 183-223
- Von Wachenfeldt, C.¹ Johnson, E.F.²

44
- 0004158099
- in press
- (2001) Chem. Res. Toxicol.
- Xue, L.¹ Wang, H.² Szklarz, G.D.³ Domanski, T.L.⁴ Halpert, J.R.⁵ Correia, M.A.⁶

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