메뉴 건너뛰기




Volumn 96, Issue 1, 2001, Pages 15-25

Asthma pathogenesis - Implications for novel therapies;Pathogenese des asthma bronchiale - Eröffnung neuer therapeutischer perspektiven

Author keywords

Asthma; Immunology; Monoclonal antibodies; Pathogenesis; Therapy

Indexed keywords

CORTICOSTEROID; IMMUNOGLOBULIN E; INTERLEUKIN 5; INTERLEUKIN 5 ANTIBODY; INTERLEUKIN 8; MONOCLONAL ANTIBODY; OMALIZUMAB;

EID: 0035863462     PISSN: 07235003     EISSN: None     Source Type: Journal    
DOI: 10.1007/pl00002148     Document Type: Review
Times cited : (4)

References (161)
  • 15
    • 0027297244 scopus 로고
    • Immunolocalization of cytokines in the nasal mucosa of normal and perennial rhinitis subjects. The mast cell as a source of IL-4, IL-5, and IL-6 in human allergic mucosal inflammation
    • (1993) J Immunol , vol.151 , pp. 3853-3865
    • Bradding, P.1    Feather, I.H.2    Wilson, S.3
  • 18
    • 0031762458 scopus 로고    scopus 로고
    • Kinetics of eotaxin expression and its relationship to eosinophil accumulation and activation in bronchial biopsies and bronchoalveolar lavage (BAL) of asthmatic patients after allergen inhalation
    • (1999) Clin Exp Immunol , vol.114 , pp. 137-146
    • Brown, J.R.1    Klemberg, J.2    Marini, M.3
  • 26
    • 0024591512 scopus 로고
    • Human interleukin-5 (IL-5) regulates the production of eosinophils in human bone marrow cultures: Comparison and interaction with IL-1, IL-3, IL-6, and GM-CSF
    • (1989) Blood , vol.73 , pp. 1504-1512
    • Clutterbuck, E.J.1    Hirst, E.M.2    Sanderson, C.J.3
  • 27
    • 17644441947 scopus 로고    scopus 로고
    • The effect of intravenous administration of a chimeric anti-IgE antibody on serum IgE levels in atopic subjects: Efficacy, safety, and pharmakokinetics
    • (1997) J Clin Invest , vol.99 , pp. 879-887
    • Corne, J.1    Djukanovic, R.2    Thomas, L.3
  • 32
    • 0029923422 scopus 로고    scopus 로고
    • Central role of immunoglobulin (1g) E in the induction of lung eosinophil infiltration and T helper 2 cell cytokine production: Inhibition by a non-anaphylactogenic anti-IgE antibody
    • (1996) J Exp Med , vol.183 , pp. 1303-1310
    • Coyle, A.J.1    Wagner, K.2    Bertrand, C.3
  • 38
    • 0032993857 scopus 로고    scopus 로고
    • Role of neutral endopeptidase and angiotensin converting enzyme in asthma
    • (1999) Pediatr Pulmonol , vol.18 , Issue.SUPPL. , pp. 103-104
    • Dusser, D.J.1
  • 48
    • 0025805744 scopus 로고
    • Parainfluenza virus infection damages inhibitory M2 muscarinic receptors on pulmonary parasympathetic nerves in the guinea pig
    • (1991) Br J Pharmacol , vol.102 , pp. 267-271
    • Fryer, A.D.1    Jacoby, D.B.2
  • 51
    • 0028821825 scopus 로고
    • Interleukin 12 inhibits antigen-induced airway hyperresponsiveness, inflammation, and Th2 cytokine expression in mice
    • (1995) J Exp Med , vol.182 , pp. 1527-1536
    • Gavett, S.H.1    O'Hearn, D.J.2    Li, X.3
  • 57
    • 17644433718 scopus 로고    scopus 로고
    • Zur entstehung von atemwegsentzündung und atemwegshyperreaktivität: Einblicke aus dem asthma-maus-modell
    • (1999) Pneumologie , vol.53 , pp. 307-312
    • Hamelmann, E.1
  • 63
    • 0029893416 scopus 로고    scopus 로고
    • Airway smooth muscle cell culture: Application to studies of airway wall remodelling and phenotype plasticity in asthma
    • (1996) Eur Respir J , vol.9 , pp. 808-820
    • Hirst, S.J.1
  • 70
  • 73
    • 0031568394 scopus 로고    scopus 로고
    • Human airway smooth muscle cells express and release RANTES in response to T helper 1 cytokines: Regulation by T helper 2 cytokines and corticosteroids
    • (1997) J Immunol , vol.158 , pp. 1841-1847
    • John, M.1    Hirst, S.J.2    Jose, P.J.3
  • 79
    • 0006390859 scopus 로고
    • The role of eosinophils in asthma
    • (1990) Lung , vol.5 , pp. 17
    • Kroegel, C.1
  • 82
    • 0026029225 scopus 로고
    • Endothelial leukocyte adhesion molecule-1 and intercellular adhesion molecule-1 mediate the adhesion of eosinophils to endothelial cells in vitro and are expressed by endothelium in allergic cutaneous inflammation in vivo
    • (1991) J Immunol , vol.146 , pp. 521-528
    • Kyan Aung, U.1    Haskard, D.O.2    Poston, R.N.3
  • 83
    • 0032846597 scopus 로고    scopus 로고
    • Negative regulation of airway responsiveness that is dependent on gammadelta T cells and independent of alphabeta T cells
    • (1999) Nat Med , vol.5 , pp. 1150-1156
    • Lahn, M.1    Kanehio, A.2    Takeda, K.3
  • 90
    • 0025774205 scopus 로고
    • Cross-linking of CD23 antigen by its natural ligand (IgE) or by anti-CD23 antibody prevents B lymphocyte proliferation and differentiation
    • (1991) J Immunol , vol.146 , pp. 2122-2129
    • Luo, H.1    Hofstetter, H.2    Banchereau, J.3
  • 107
    • 0030637626 scopus 로고    scopus 로고
    • Interleukin 4: Signalling mechanisms and control of T cell differentiation
    • (1997) Ciba Found Syrup , vol.204 , pp. 208-216
    • Paul, W.E.1
  • 109
    • 0028034234 scopus 로고
    • Difficulties and dangers of vaccination strategies for asthma and other autoimmune disorders
    • (1994) Lancet , vol.344 , pp. 1227-1228
    • Petrovsky, N.1
  • 117
    • 0027395050 scopus 로고
    • T cells expressing specific Vβ elements regulate immunoglobulin E production and airways responsiveness in vivo
    • (1993) J Exp Med , vol.177 , pp. 1175-1180
    • Renz, H.1    Bradley, K.2    Saloga, J.3
  • 118
    • 0027320031 scopus 로고
    • Activation of CD4+ T cells, increased Th2-type cytokine mRNA expression, and eosinophil recruitment in bronchoalveolar lavage after allergen inhalation challenge in patients with atopic asthma
    • (1993) J Allergy Clin Immunol , vol.92 , pp. 313-324
    • Robinson, D.1    Hamid, Q.2    Bentley, A.3
  • 119
    • 0027408883 scopus 로고
    • Activated memory T helper cells in bronchoalveolar lavage fluid from patients with atopic asthma: Relation to asthma symptoms, lung function, and bronchial responsiveness
    • (1993) Thorax , vol.48 , pp. 26-32
    • Robinson, D.S.1    Bentley, A.M.2    Hartnell, A.3
  • 128
    • 0025245434 scopus 로고
    • Ablation of eosinophil and IgE responses with anti-IL-5 or anti-IL-4 antibodies fails to affect immunity against Schistosoma mansoni in the mouse
    • (1990) J Immunol , vol.145 , pp. 3911-3916
    • Sher, A.1    Coffman, R.L.2    Hieny, S.3
  • 140
    • 0025769977 scopus 로고
    • Effects of IL-5, granulocyte/macrophage colony-stimulating factor (G M-CSF) and IL-3 on the survival of blood eosinophils in vitro
    • (1991) Clin Exp Immunol , vol.85 , pp. 312-316
    • Tai, P.C.1    Sun, L.2    Spry, C.J.3
  • 142
    • 0007522448 scopus 로고    scopus 로고
    • Genes for asthma? An analysis of the European Community Respiratory Health Survey
    • (1997) Am J Respir Crit Care Med , vol.156 , pp. 1773-1780
  • 143
    • 0032565364 scopus 로고    scopus 로고
    • Worldwide variation in prevalence of symptoms of asthma allergic rhinoconjunctivitis, and atopic eczema
    • ISAAC
    • (1998) Lancet , vol.351 , pp. 1225-1232
  • 152
    • 0026666718 scopus 로고
    • Allergic and nonallergic asthmatics have distinct patterns of T-Cell activation and cytokine production in peripheral blood and bronchoalveolar lavage
    • (1992) Am Rev Respir Dis , vol.146 , pp. 109-115
    • Walker, C.1    Bode, E.2    Boer, L.3
  • 159
    • 0031852598 scopus 로고    scopus 로고
    • Interleukin-12 as a target for modulation of the inflammatory response in asthma
    • (1998) Allergy , vol.53 , pp. 113-119
    • Wills-Karp, M.1
  • 161
    • 0032903716 scopus 로고    scopus 로고
    • Growth factors secreted by bronchial epithelial cells control myofibroblast proliferation: An in vitro co-culture model of airway remodelling in asthma
    • (1999) Lab Invest , vol.79 , pp. 395-405
    • Zhang, S.1    Smartt, H.2    Holgate, S.T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.