Human Airway Smooth Muscle Cells Express and Release RANTES in Response to T Helper 1 Cytokines: Regulation by T Helper 2 Cytokines and Corticosteroids

Journal of Immunology

Volumn 158, Issue 4, 1997, Pages 1841-1847

  John, Matthias ^a   Hirst, Stuart J ^b   Jose, Peter J ^a   Robichaud, Annette ^a   Berkman, Neville ^a   Witt, Christian ^c   Twort, Charles H C ^b   Barnes, Peter J ^a   Chung, K Fan ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b ST THOMAS HOSPITAL   (United Kingdom)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID; CYTOKINE; DEXAMETHASONE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 4; MACROPHAGE INFLAMMATORY PROTEIN 1; MESSENGER RNA; RANTES; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; BIOSYNTHESIS; BRONCHUS; CELL CULTURE; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; EOSINOPHIL; FEMALE; GENETICS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MALE; METABOLISM; NEUTROPHIL CHEMOTAXIS; PHYSIOLOGY; SMOOTH MUSCLE; TH1 CELL; TH2 CELL;

ADRENAL CORTEX HORMONES; BRONCHI; CELLS, CULTURED; CHEMOTAXIS, LEUKOCYTE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOKINES; DEXAMETHASONE; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; EOSINOPHILS; FEMALE; HUMANS; INTERFERON TYPE II; INTERLEUKIN-10; INTERLEUKIN-13; INTERLEUKIN-4; MACROPHAGE INFLAMMATORY PROTEIN-1; MALE; MUSCLE, SMOOTH; RANTES; RNA, MESSENGER; TH1 CELLS; TH2 CELLS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0031568394     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Bousquet, J., P. Chanez, J. Y. Lacoste, G. Barneon, N. Ghavanian, I. Enander, P. Venge, S. Ahlstedt, J. Simony-Lafontaine, P. Godard, and F. B. Michel. 1990. Eosinophilic inflammation in asthma. N. Engl. J. Med. 323:1033.
2. Djukanovic, R., J. W. Wilson, K. M. Britten, S. J. Wilson, A. F. Walls, W. R. Roche, P. H. Howarth, and S. T. Holgate. 1990. Quantitation of mast cells and eosinophils in the bronchial mucosa of symptomatic atopic asthmatics and healthy control subjects using immunohistochemistry. Am. Rev. Respir. Dis. 142:863.
3. Poston, R., P. Chanez, J. Y. Lacoste, P. Litchfield, T. H. Lee, and J. Bousquet. 1992. Immunohistochemical characterization of the cellular infiltration of asthmatic bronchi. Am. Rev. Respir. Dis. 145:918.
4. Azzawi, M., B. Bradley, P. K. Jeffrey, A. J. Frew, A. J. Wardlaw, G. Knowles, B. Assoufi, J. V. Collins, S. Durham, and A. B. Kay. 1990. Identification of activated T lymphocytes and eosinophils in bronchial biopsies in stable atopic asthmatics. Am. Rev. Respir. Dis. 142:1407.
5. Roche, W. R., R. Beasley, J. H. Williams, and S. T. Holgate. 1989. Subepithelial fibrosis in the bronchi of asthmatics. Lancet 1:S20.
6. Ebina, M., T. Takahashi, T. Chiba, and M. Motomiya. 1993. Cellular hypertrophy and hyperplasia of airway smooth muscle underlying bronchial asthma. Am. Rev. Respir. Dis. 148:720.
7. James, A. L., P. D. Pare, and J. C. Hogg. 1989. The mechanics of airway narrowing in asthma. Am. Rev. Respir. Dis. 139:242.
8. Hirst, S. J. 1996. Airway smooth muscle cell culture: application to studies of airway wall remodelling and phenotype plasticity in asthma. Eur. Respir. J. 9:808.
9. Schall, T. J., J. Jongstra, B. J. Dyer, J. Jorgensen, C. Clayberger, M. M. Davis, and A. M. Krensky. 1992. A human T cell-specific molecule is a member of a new gene family. J. Immunol. 141:1018.
10. Schall, T. J., K. Bacon, K. J. Toy, and D. V. Goeddel. 1990. Selective attraction of monocytes and T lymphocytes of the memory phenotype of cytokine RANTES. Nature 347:669.
11. Rot, A., M. Krieger, T. Brunner, S. C. Bischoff, T. J. Schall, and C. A. Dahinden. 1992. RANTES and macrophage inflammatory protein 1α induce the migration and activation of normal human eosinophil granulocytes. J. Exp. Med. 176:1489.
12. Kameyoshi, Y., A. Dörschner, A. I. Mallet, E. Christophers, and J. Schröder. 1992. Cytokine RANTES released by thrombin-stimulated platelets is a potent attractant for human eosinophils. J. Exp. Med. 176:587.
13. Devergne, O., A. Marfaing-Koka, T. J. Schall, M. B. Leger-Ravet, M. Sadick, M. C. Crevon, K. J. Kim, T. T. Schall, P. Galanaud, and D. Emilie. 1994. Production of the RANTES chemokine in delayed-type hypersensitivity reactions: involvement of macrophages and endothelial cells. J. Exp. Med. 179:1689.
14. Marfaing-Koka, A., O. Devergne, G. Gorgone, A. Portier, T. J. Schall, P. Galanaud, and D. Emilie. 1995. Regulation of the production of the RANTES chemokine by endothelial cells: synergistic induction by IFN plus TNF-α and inhibition by IL-4 and IL-13. J. Immunol. 154:1870.
15. Rathanaswami, P., M. Hachicha, M. Sadick, T. J. Schall, and S. R. McColl. 1993. Expression of the cytokine RANTES in human rheumatoid synovial fibroblasts: differential regulation of RANTES and interleukin-8 genes by inflammatory cytokines. J. Biol. Chem. 268:5834.
16. Berkman, N., A. Robichaud, V. L. Krishnan, G. Roesems, R. A. Robbins, P. J. Jose, P. J. Barnes, and K. F. Chung. 1995. Expression of RANTES in human airway epithelial cells: effect of corticosteroids & interleukin-4, -10 and -13. Immunology 87:599.
17. Hirst, S. J., P. J. Barnes, and C. H. L. Twort. 1992. Quantifying proliferation of cultured human and rabbit airway smooth muscle cells in response to serum and platelet-derived growth factor. Am. J. Respir. Cell Mol. Biol. 7:574.
18. Twort, C. H. C., and C. van Breemen. 1988. Human airway smooth muscle in culture. Tissue Cell 20:139.
19. Chomczynski, P., and N. Sacchi. 1987. Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156.
20. Kwon, O. J., P. J. Jose, R. A. Robbins, T. J. Schall, T. J. Williams, and P. J. Barnes. 1995. Glucocorticoid inhibition of RANTES expression in human lung epithelial cells. Am. J. Respir. Cell Mol. Biol. 12:488.
21. Jose, P. J., I. K. Moss, R. N. Maini, and T. J. Williams. 1990. Measurement of the chemotactic complement fragment C5a in rheumatoid synovial fluids by radioimmunoassay: role of C5a in the acute inflammatory phase. Ann. Rheum. Dis. 49:747.
22. Pattison, J., P. J. Nelson, P. Huie, I. von Leuttichau, G. Farshid, R. K. Sibley, and A. M. Krensky. 1994. RANTES chemokine expression in cell-mediated transplant rejection of the kidney. Lancet 343:209.
23. Feinman, R., D. Henriksen-DeStefano, M. Tsujimoto, and J. Vilcek. 1987. Tumor necrosis factor is an important mediator of tumor cell killing by human monocytes. J. Immunol. 138:635.
24. Liew, F. Y., Y. Li, and S. Millott. 1990. Tumor necrosis factor-α synergizes with IFN-γ in mediating killing of Leishmania major through the induction of nitric oxide. J. Immunol. 145:4306.
25. Kamijo, R., H. Harada, T. Matsuyama, M. Bosland, J. Gerecitano, D. Shapiro, J. Le, S. I. Koh, T. Kimura, and S. J. Green. 1994. Requirement for transcription factor IRF-1 in NO synthase induction in macrophages. Science 263:1612.
26. Krakauer, T., and J. J. Oppenheim. 1993. IL-1 and tumor necrosis factor-α each up-regulate both the expression of IFN-γ receptors and enhance IFN-γ-induced HLA-DR expression on human monocytes and a human monocytic cell line (THP-1). J. Immunol. 150:1205.
27. Sanceau, J., G. Merlin, and J. Wietzerbin. 1992. Tumor necrosis factor-α and IL-6 up-regulate IFN-γ receptor gene expression in human monocytic THP-1 cells by transcriptional and post-transcriptional mechanisms. J. Immunol. 149:1671.
28. Yasumoto, K., S. Okamoto, N. Mukaida, S. Murakami, M. Mai, and K. Matsushima. 1992. Tumor necrosis factor alpha and interferon gamma synergistically induce interleukin 8 production in a human gastric cancer cell line through acting concurrently on AP-1 and NF-κB-like binding sites of the interleukin 8 gene. J. Biol. Chem. 267:22506.
29. Nelson, P. J., H. T. Kim, W. C. Manning, T. J. Goralski, and A. M. Krensky. 1993. Genomic organization and transcriptional regulation of the RANTES chemokine gene. J. Immunol. 151:2601.
30. Stewart, A. G., P. R. Tomlinson, D. J. Fernandes, J. W. Wilson, and T. Harris. 1995. Tumor necrosis factor-α modulates mitogenic responses of human cultured airway smooth muscle. Am. J. Respir. Cell Mol. Biol. 12:110.
31. Ponath, P. D., S. Qin, D. J. Ringler, I. Clark-Lewis, J. Wang, N. Kassam, H. Smith, X. Shi, J. Gonzalo, W. Newman, J. Gutierrez-Ramos, and C. R. Mackay. 1996. Cloning of the human eosinophil chemoattractant, eotaxin: expression, receptor binding, and functional properties suggest a mechanism for the selective recruitment of eosinophils. J. Clin. Invest. 97:604.
32. Mossman, T. R., and R. L. Coffman. 1989. Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol. 7:145.
33. Favre, C., S. Saeland, C. Caux, V. Ouvert, and J. E. De Vries. 1990. Interleukin 4 has basophilic and eosinophilic cell growth-promoting activity on cord blood cells. Blood 75:67.
34. Clutterbuck, E. J., E. M. Hirst, and C. J. Sanderson. 1989. Human interleukin-5 (IL-5) regulates the production of eosinophils in human bone marrow cultures: comparison and interaction with IL-1, IL-3, IL-6 and GM-CSF. Blood 73:1504.
35. Sanderson, C. J., D. J. Warren, and M. Strath. 1985. Identification of a lymphokine that stimulates eosinophil differentiation in vitro: its relationship to interleukin 3, and functional properties of eosinophils produced in cultures. J. Exp. Med. 162:60.
36. Hamid, Q., M. Azzawi, S. Ying, R. Moqbel, A. J. Wardlaw, C. J. Corrigan, B. Bradley, S. R. Durham, J. V. Collins, and P. R. Jeffery. 1991. Expression of mRNA for interleukins in mucosal bronchial biopsies from asthma. J. Clin. Invest. 87:1541.
37. Robinson, D. S. 1996. Increased IL-10 mRNA expression in atopic allergy and asthma. Am. J. Respir. Cell Mol. Biol. 14:113.
38. Abehsira-Amar, O., M. Gibert, M. Joliy, J. Theze, and D. L. Jankovic. 1992. IL-4 plays a dominant role in the differential development of Th0 into Th1 and Th2 cells. J. Immunol. 148:3820.
39. Essner, R., K. Rhoades, W. H. McBride, D. L. Morton, and J. S. Economou. 1989. IL-4 down-regulates IL-1 and TNF gene expression in human monocytes. J. Immunol. 142:3857.
40. Minty, A., P. Chalon, J. Derocq, X. Dumont, J. Guillemot, M. Kaghad, C. Labit, P. Leplatois, P. Liauzun, B. Miloux, C. Minty, P. Casellas, G. Loison, J. Lupker, D. Shire, P. Ferrara, and D. Caput. 1993. Interleukin-13 is a new human lymphokine regulating inflammatory and immune responses. Nature 362:248.
41. De Waal Malefyt, R., C. G. Figdor, R. Huijbens, S. Mohan-Peterson, B. Bennett, J. Culpepper, W. Dang, G. Zurawski, and J. E. De Vries. 1993. Effects of IL-13 on phenotype, cytokine production, and cytotoxic function of human monocytes. J. Immunol. 151:6370.
42. Cembrzynska-Norvak, M., E. Szklarz, A. D. Inglot, and J. A. Teodorczyk-Injeyan. 1993. Elevated release of TNF-α and interferon-gamma by bronchoalveolar leukocytes from patients with bronchial asthma. Am. Rev. Respir. Dis. 147:291.
43. Lazaar, A. L., S. M. Albelda, J. M. Pilewski, B. Brennan, E. Pure, and R. A. Panettieri. 1994. T lymphocytes adhere to airway smooth muscle cells via integrins and CD44 and induce smooth muscle cell DNA synthesis. J. Exp. Med. 180:807.
44. + T cells in response to MIP-1α and MIP-1β. Science 260:355.