Interleukin-10 and transforming growth factor-β promoter polymorphisms in allergies and asthma

American Journal of Respiratory and Critical Care Medicine

Volumn 158, Issue 6, 1998, Pages 1958-1962

  Hobbs, Kathryn ^a,b   Negri, Julie ^a   Klinnert, Mary ^a   Rosenwasser, Lanny J ^a   Borish, Larry ^a  

^a NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA;

APOPTOSIS; ARTICLE; ASTHMA; BASE PAIRING; EOSINOPHIL; GENETIC POLYMORPHISM; HUMAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROMOTER REGION;

EID: 0032445196     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.158.6.9804011     Document Type: Article

References (34)

1. Bonfield, T. L., M. W. Konstan, P. Burfeind, J. R. Panuska, J. B. Hilliard, and M. Berger. 1995. Normal bronchial epithelial cells constitutively produce the anti-inflammatory cytokine interleukin-10, which is down-regulated in cystic fibrosis. Am. J. Respir. Cell Mol. Biol. 13:257-261.
2. Borish, L., A. Aarons, J. Rumbyrt, P. Cvietusa, J. Negri, and S. Wenzel. 1996. Interleukin-10 regulation in normal and asthmatic subjects. J. Allergy Clin. Immunol. 97:1288-1296.
3. McCartney-Francis, N. L., and S. Wahl. 1995. Transforming growth factor beta: a matter of life and death. J. Leuk. Biol. 55:401-409.
4. Aubert, J.-D., B. I. Dalal, T. R. Bai, C. R. Roberts, S. Hayashi, and J. C. Hogg. 1994. Transforming growth factor β1 gene expression in human airways. Thorax 49:225-232.
5. Ohmori, H., T. Kanda, T. Takai, and M. Hikida. 1995. Induction of antigen-specific IgE response in murine lymphocytes by IL-10. Immunol. Lett. 47:127-132.
6. Mrazek, D. A., M. Klinnert, P. Mrazek, and T. Macey. 1991. Early asthma onset: consideration of parenting issues. J. Am. Acad. Child. Adolescent Psych. 30:277-282.
7. Klinnert, M., P. Mrazek, and D. A. Mrazek. 1994. Early asthma onset: the interaction between family stressors and adaptive parenting. Psychiatry 57:51-61.
8. Orita, M., Y. Suzuki, T. Sekiya, and K. Hayashi. 1989. Rapid and sensitive detection of point mutations and DNA polymorphisms using polymerase chain reaction. Genomics 5:874-879.
9. Orita, M., H. Iwahana, H. Kanazawa, K. Hayashi, and T. Sekiya. 1989. Detection of polymorphisms of human DNA by gel electrophoresis as a single-stranded conformation polymorphism. Proc. Natl. Acad. Sci. U.S.A. 86:2766-2770.
10. Van den Akker, E., J. E. F. Braun, G. Pals, M. V. M. Lafleur, and J. Retel. 1992. Single base mutations can be unequivocally and rapidly detected by analysis of DNA heteroduplexes, obtained with deletion-mutant instead of wild type DNA. Nucleic Acids Res. 20:6745-6746.
11. Kim, S.-J., A. Glick, M. B. Sporn, and A. B. Roberts. 1989. Characterization of the promoter region of the human transforming growth factor-β1 gene. J. Biol. Chem. 264:402-408.
12. Shrivastava, A., and K. Calame. 1994. An analysis of genes regulated by the multi-functional transcriptional regulatory Yin Yang-1. Nucleic Acids Res. 24:5151-5155.
13. Borish, L. Interleukin-10: evolving concepts. J. Allergy Clin. Immunol. (In press)
14. Del Prete, G., M. De Carli, F. Almerigogna, M. G. Giudizi, R. Biagiotti, and S. Romagnani. 1993. Human IL-10 is produced by both type 1 helper (Th1) and type 2 helper (Th2) T cell clones and inhibits their antigen-specific proliferation and cytokine production. J. Immunol. 150:353-360.
15. de Waal Malefyt, R., J. Haanen, H. Spits, M. G. Roncarolo, A. te Velde, C. Figdor, K. Johnson, R. Kastelein, H. Yssel, and J. E. de Vries. 1991. Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression. J. Exp. Med. 174:915-924.
16. Enk, A. H., V. L. Angeloni, M. C. Udey, and S. I. Katz. 1993. Inhibition of Langerhans cell antigen-presenting function by IL-10: a role for IL-10 in induction of tolerance. J. Immunol. 151:2390-2398.
17. Becker, J. C., C. Czerny, and E.-B. Brocker. 1994. Maintenance of clonal anergy by endogenously produced IL-10. Int. Immunol. 6:1605-1612.
18. Takanaski, S., R. Nonaka, Z. Xing, P. O'Byrne, J. Dolovich, and M. Jordana. 1994. Interleukin 10 inhibits lipopolysaccharide-induced survival and cytokine production by human peripheral blood eosinophils. J. Exp. Med. 180:711-715.
19. Punnonen, J., R. de Waal Malefyt, P. Van Vlasselae, J.-F. Gauchat, and J. E. de Vries. 1993. IL-10 and viral IL-10 prevent IL-4-induced IgE synthesis by inhibiting the accessory cell function of monocytes. J. Immunol. 151:1280-1289.
20. Zuany-Amorim, C., S. Haile, D. Leduc, C. Dumarey, M. Huerre, B. B. Vargaftig, and M. Pretolani. 1995. Interleukin-10 inhibits antigen-induced cellular recruitment into the airways of sensitized mice. J. Clin. Invest. 95:2644-2651.
21. Grunig, G., D. B. Corry, M. W. Leach, B. W. P. Seymour, V. P. Kurup, and D. M. Rennick. 1997. Interleukin-10 is a natural suppressor of cytokine production and inflammation in a murine model of allergic bronchopulmonary aspergillosis. J. Exp. Med. 185:1089-1099.
22. Martinez, J. A. B., T. E. King, Jr., K. Brown, C. A. Jennings, L. Borish, R. L. Mortenson, T. Z. Khan, T. W. Bost, and D. W. H. Riches. 1997. Increased expression of the interleukin 10 gene in alveolar macrophages in interstitial lung diseases. Lung Cell. Mol. Physiol. 17:L676-683.
23. Rousset, F., E. Garcia, T. Defrance, C. Peronne, N. Vezzio, D. H. Hsu, R. Kastelein, K. W. Moore, and J. Banchereau. 1992. Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes. Proc. Natl. Acad. Sci. U.S.A. 89:1890-1893.
24. Briere, F., C. Servet-Delprat, J.-M. Bridon, J.-M. Saint-Remy, and J. Banchereau. 1994. Human interleukin 10 induces naive surface immunoglobulin D+ (sIgD+) B cells to secrete IgG1 and IgG3. J. Exp. Med. 179:757-762.
25. Ohmen, J. D., J. M. Hanifin, and B. J. Nickoloff. 1995. Overexpression of IL-10 in atopic dermatitis: contrasting cytokine patterns with delayed-type hypersensitivity reactions. J. Immunol. 154:1956-1963.
26. Tsunawaki, S., M. Sporn, A. Ding, and C. Nathan. 1998. Deactivation of macrophages by transforming growth factor-β. Nature 334:260-262.
27. Toossi, Z. 1996. Decreased production of TGFβ-1 by human alveolar macrophages as compared with blood monocytes. J. Immunol. 156: 3461-3468.
28. Shull, M. M., I. Ormsby, A. Kier, S. Pawlowski, R. J. Diebold, M. Yin, R. Allen, C. Sidman, G. Proetzel, and D. Calvin. 1992. Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory disease. Nature 359:693-699.
29. Alam, R. 1994. Transforming growth factor β abrogates the effects of hematopoietins on eosinophils and induces their apoptosis. J. Exp. Med. 179:1041-1045.
30. Ohno, I., R. G. Lea, K. C. Flanders, D. A. Clark, D. Banwatt, J. Dolovich, J. Denburg, C. B. Harley, J. Gauldie, and M. Jordana. 1992. Eosinophils in chronically inflamed human upper airway tissues express transforming growth factor β1 gene. J. Clin. Invest. 89:1662-1668.
31. Mascali, J., L. Borish, A. Aarons, J. Rumbyrt, and D. Klemm. 1995. Sequence and characterization of the human interleukin (IL)-10 promoter (abstract). J. Allergy Clin. Immunol. 95:343A.
32. Turner, D. M., D. M. Williams, D. Sankaran, M. Lazarus, P. J. Sinnott, and I. V. Hutchinson. 1997. An investigation of polymorphisms in the interleukin-10 gene promoter. Eur. J. Immunogenet. 24:1-8.
33. Kehrl, J. H., C. Thevenin, P. Rieckmann, and A. Fauci. 1991. Transforming growth factor-β suppresses human B lymphocyte Ig production by inhibiting synthesis and the switch from the membrane form to the secreted form of Ig mRNA. J. Immunol. 146:4016-4023.
34. Lazarus, M., A. H. Hajeer, D. Turner, P. Sinnott, J. Worthington, W. E. Ollier, and I. V. Hutchinson. 1997. Genetic variation in the interleukin 10 gene promoter and systemic lupus erythematosus. J. Rheum. 24: 2314-2317.