Glucocorticoids decrease tissue mast cell number by reducing the production of the c-kit ligand, stem cell factor, by resident cells. In vitro and in vivo evidence in murine systems

Journal of Clinical Investigation

Volumn 99, Issue 7, 1997, Pages 1721-1728

  Finotto, Susetta ^a   Mekori, Yoseph A ^b   Metcalfe, Dean D ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b TEL AVIV UNIVERSITY   (Israel)

Author keywords

apoptosis; fibroblasts; glucocorticoids; mast cells; stem cell factor

Indexed keywords

GLUCOCORTICOID; STEM CELL FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL COUNT; CELL HYPERPLASIA; CONTROLLED STUDY; DOWN REGULATION; FIBROBLAST; HORMONAL REGULATION; IMMUNOHISTOCHEMISTRY; INFLAMMATORY CELL; MAST CELL; MEMBRANE BINDING; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0030937094     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119336     Document Type: Article

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