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Volumn 70, Issue 4, 1996, Pages 1067-1079

Active p21Ras is sufficient for rescue of NGF-dependent rat sympathetic neurons

Author keywords

apoptosis; c Fos; signal transduction; staurosporine; trk; tyrosine phosphorylation

Indexed keywords

NERVE GROWTH FACTOR; ONCOPROTEIN; PHORBOL ESTER; STAUROSPORINE;

EID: 0030024318     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/0306-4522(95)00420-3     Document Type: Article
Times cited : (41)

References (49)
  • 1
    • 0022137480 scopus 로고
    • Microinjection of the p21ras oncogene protein into PC12 cells increases morphological differentiation
    • Bar-Sagi D. and Feramisco J. R. (1985) Microinjection of the p21ras oncogene protein into PC12 cells increases morphological differentiation. Cell 42, 841-848.
    • (1985) Cell , vol.42 , pp. 841-848
    • Bar-Sagi, D.1    Feramisco, J.R.2
  • 2
    • 0024677597 scopus 로고
    • Trophic factors and neuronal survival
    • Barde Y.-A. (1989) Trophic factors and neuronal survival. Neuron 2, 1525-1534.
    • (1989) Neuron , vol.2 , pp. 1525-1534
    • Barde, Y.-A.1
  • 3
    • 0024326959 scopus 로고
    • Ras p21 protein promotes survival and fibre outgrowth of cultured embryonic neurons
    • Borasio G. D., John J., Wittinghofer A., Barde Y.-A., Sendtner M. and Heumann R. (1989) Ras p21 protein promotes survival and fibre outgrowth of cultured embryonic neurons. Neuron 2, 1087-1096.
    • (1989) Neuron , vol.2 , pp. 1087-1096
    • Borasio, G.D.1    John, J.2    Wittinghofer, A.3    Barde, Y.-A.4    Sendtner, M.5    Heumann, R.6
  • 4
    • 0025190264 scopus 로고
    • Differential effects of the protein kinase inhibitor K252a on the in vitro survival of chick embryonic neurons
    • Borasio G. D. (1990) Differential effects of the protein kinase inhibitor K252a on the in vitro survival of chick embryonic neurons. Neurosci. Lett. 108, 207-212.
    • (1990) Neurosci. Lett. , vol.108 , pp. 207-212
    • Borasio, G.D.1
  • 5
    • 0027256842 scopus 로고
    • Involvement of ras p21 in neurotrophin-induced response of sensory but not sympathetic neurons
    • Borasio G. D., Markus A., Wittinghofer A., Barde Y.-A. and Heumann R. (1993) Involvement of ras p21 in neurotrophin-induced response of sensory but not sympathetic neurons. J. Cell Biol. 121, 665-672.
    • (1993) J. Cell Biol. , vol.121 , pp. 665-672
    • Borasio, G.D.1    Markus, A.2    Wittinghofer, A.3    Barde, Y.-A.4    Heumann, R.5
  • 6
    • 0025764353 scopus 로고
    • Nerve growth factor is required for the induction of c-fos immunoreaclivity by serum, depolarisation, cyclic AMP or trauma in cultured rat sympathetic neurons
    • Buckmaster E. A., Nobes C. D., Edwards S. N. and Tolkovsky A. M. (1991) Nerve growth factor is required for the induction of c-fos immunoreaclivity by serum, depolarisation, cyclic AMP or trauma in cultured rat sympathetic neurons. Eur. J. Neurosci. 3, 698-707.
    • (1991) Eur. J. Neurosci. , vol.3 , pp. 698-707
    • Buckmaster, E.A.1    Nobes, C.D.2    Edwards, S.N.3    Tolkovsky, A.M.4
  • 7
    • 0021152619 scopus 로고
    • A monoclonal antibody modulates the interaction of nerve growth factor with PC12 cells
    • Chandler C. E., Parsons L. M., Hosang M. and Shooter E. M. (1984) A monoclonal antibody modulates the interaction of nerve growth factor with PC12 cells. J. biol. Chem. 259, 6882-6889.
    • (1984) J. Biol. Chem. , vol.259 , pp. 6882-6889
    • Chandler, C.E.1    Parsons, L.M.2    Hosang, M.3    Shooter, E.M.4
  • 8
    • 0025283961 scopus 로고
    • Developmental cell death: Morphological diversity and multiple mechanisms
    • Clarke P. D. H. (1990) Developmental cell death: morphological diversity and multiple mechanisms. Anat. Embryol. 181, 195-213.
    • (1990) Anat. Embryol. , vol.181 , pp. 195-213
    • Clarke, P.D.H.1
  • 11
    • 0010332197 scopus 로고
    • Insulin growth factors regulate mitotic cycle in cultured rat sympathetic neuroblasts
    • DiCicco-Bloom E. and Black I. B. (1988). Insulin growth factors regulate mitotic cycle in cultured rat sympathetic neuroblasts. Proc. natn. Acad. Sci. U.S.A. 85, 4066-4070.
    • (1988) Proc. Natn. Acad. Sci. U.S.A. , vol.85 , pp. 4066-4070
    • DiCicco-Bloom, E.1    Black, I.B.2
  • 12
    • 0025339297 scopus 로고
    • Neuroblast mitosis in dissociated cultures: Regulation and relationship to differentiation
    • DiCicco-Bloom E., Townes-Anderson E. and Black I. B. (1990). Neuroblast mitosis in dissociated cultures: regulation and relationship to differentiation. J. Cell Biol. 110, 2073-2086.
    • (1990) J. Cell Biol. , vol.110 , pp. 2073-2086
    • DiCicco-Bloom, E.1    Townes-Anderson, E.2    Black, I.B.3
  • 13
    • 0025786538 scopus 로고
    • The death programme in sympathetic neurons can be suppressed at the post-translational level by NGF, cyclic AMP and depolarization
    • Edwards S. N., Buckmaster A. E. and Tolkovsky A. M. (1991) The death programme in sympathetic neurons can be suppressed at the post-translational level by NGF, cyclic AMP and depolarization. J. Neurochem. 57, 2140-2143.
    • (1991) J. Neurochem. , vol.57 , pp. 2140-2143
    • Edwards, S.N.1    Buckmaster, A.E.2    Tolkovsky, A.M.3
  • 14
    • 0028123667 scopus 로고
    • Characterisation of apoptosis in cultured rat sympathetic neurons after nerve growth factor (NGF) withdrawal
    • Edwards S. N. and Tolkovsky A. M. (1994) Characterisation of apoptosis in cultured rat sympathetic neurons after nerve growth factor (NGF) withdrawal. J. Cell Biol. 124, 537-546.
    • (1994) J. Cell Biol. , vol.124 , pp. 537-546
    • Edwards, S.N.1    Tolkovsky, A.M.2
  • 15
    • 0025092051 scopus 로고
    • Ras induced c-Fos expression and proliferation in living rat fibroblasts involves C kinase activation and the serum response element pathway
    • Gauthier-Rouviere C., Fernandez A. and Lamb N. J. C. (1990) Ras induced c-Fos expression and proliferation in living rat fibroblasts involves C kinase activation and the serum response element pathway. Eur. molec. Biol. Org. J. 9, 171-180.
    • (1990) Eur. Molec. Biol. Org. J. , vol.9 , pp. 171-180
    • Gauthier-Rouviere, C.1    Fernandez, A.2    Lamb, N.J.C.3
  • 16
    • 0344046620 scopus 로고
    • Experimental autoimmune model of nerve growth factor deprivation: Effects on developing peripheral sympathetic and sensory neurons
    • Gorin P. D. and Johnson E. M. Jr (1979) Experimental autoimmune model of nerve growth factor deprivation: effects on developing peripheral sympathetic and sensory neurons. Proc. natn. Acad. Sci. U.S.A. 76, 5382-5386.
    • (1979) Proc. Natn. Acad. Sci. U.S.A. , vol.76 , pp. 5382-5386
    • Gorin, P.D.1    Johnson E.M., Jr.2
  • 17
    • 0023038434 scopus 로고
    • Activated N-ras gene induces neuronal differentiation of PC12 rat pheochromocytoma cells
    • Guerrero I., Pellicer A. and Burstein D. (1986) Activated N-ras gene induces neuronal differentiation of PC12 rat pheochromocytoma cells. J. Physiol. 129, 71-76.
    • (1986) J. Physiol. , vol.129 , pp. 71-76
    • Guerrero, I.1    Pellicer, A.2    Burstein, D.3
  • 18
    • 0022602017 scopus 로고
    • Inhibition of nerve growth factor induced differentiation of PC12 cells by microinjection of antibodies to ras p21
    • Hagag N., Halegoua S. and Viola M. (1986) Inhibition of nerve growth factor induced differentiation of PC12 cells by microinjection of antibodies to ras p21. Nature 319, 680-682.
    • (1986) Nature , vol.319 , pp. 680-682
    • Hagag, N.1    Halegoua, S.2    Viola, M.3
  • 19
    • 0018322590 scopus 로고
    • Long-term culture of dissociated sympathetic neurons
    • Hawrot E. and Patterson P. H. (1979) Long-term culture of dissociated sympathetic neurons. Meth. Enzym. 58, 574-584.
    • (1979) Meth. Enzym. , vol.58 , pp. 574-584
    • Hawrot, E.1    Patterson, P.H.2
  • 20
    • 0021956410 scopus 로고
    • Molecular characteristics of nerve growth factor receptors on PC12 cells
    • Hosang M. and Shooter E. M. (1985) Molecular characteristics of nerve growth factor receptors on PC12 cells. J. biol. Chem. 260, 655-662.
    • (1985) J. Biol. Chem. , vol.260 , pp. 655-662
    • Hosang, M.1    Shooter, E.M.2
  • 21
    • 0025237135 scopus 로고
    • Nerve growth factor acts through cAMP-dependent protein kinase to increase the number of sodium channels in PC12 cells
    • Kalman D., Wong B., Horvai A. E., Cline M. J. and O'Lague P. H. (1990) Nerve growth factor acts through cAMP-dependent protein kinase to increase the number of sodium channels in PC12 cells. Neuron 4, 355-366.
    • (1990) Neuron , vol.4 , pp. 355-366
    • Kalman, D.1    Wong, B.2    Horvai, A.E.3    Cline, M.J.4    O'Lague, P.H.5
  • 22
    • 0025735392 scopus 로고
    • The trk proto-oncogene product: A signal transducing receptor for nerve growth factor
    • Kaplan D. R., Hempstead B. L., Martin-Zanca D., Chao M. V. and Parada L. F. (1991) The trk proto-oncogene product: a signal transducing receptor for nerve growth factor. Science 252, 554-558.
    • (1991) Science , vol.252 , pp. 554-558
    • Kaplan, D.R.1    Hempstead, B.L.2    Martin-Zanca, D.3    Chao, M.V.4    Parada, L.F.5
  • 23
    • 0025797396 scopus 로고
    • Tyrosine phosphorylation and tyrosine kinase activity of the trk proto-oncogene product induced by NGF
    • Kaplan D. R., Martin-Zanca D. and Parada L. F. (1991) Tyrosine phosphorylation and tyrosine kinase activity of the trk proto-oncogene product induced by NGF. Nature 350, 158-160.
    • (1991) Nature , vol.350 , pp. 158-160
    • Kaplan, D.R.1    Martin-Zanca, D.2    Parada, L.F.3
  • 24
    • 0028115022 scopus 로고
    • Neurotrophin signal-transduction by the trk receptor
    • Kaplan D. R. and Stephens R. M. (1994) Neurotrophin signal-transduction by the trk receptor. J. Neurobiol. 25, 1404-1417.
    • (1994) J. Neurobiol. , vol.25 , pp. 1404-1417
    • Kaplan, D.R.1    Stephens, R.M.2
  • 25
    • 0025857391 scopus 로고
    • The trk proto-oncogene encodes a receptor for nerve growth factor
    • Klein R., Jing S., Nanduri V., O'Rourke E. and Barbacid M. (1991) The trk proto-oncogene encodes a receptor for nerve growth factor. Cell 65, 189-197.
    • (1991) Cell , vol.65 , pp. 189-197
    • Klein, R.1    Jing, S.2    Nanduri, V.3    O'Rourke, E.4    Barbacid, M.5
  • 26
    • 0026616905 scopus 로고
    • Neurotrophin-induced trk receptor phosphorylation and cholinergic neuron response in primary cultures of embryonal rat brain neurons
    • Knusel B., Rabin S., Swidmer H. R., Hefti R. and Kaplan D. R. (1992) Neurotrophin-induced trk receptor phosphorylation and cholinergic neuron response in primary cultures of embryonal rat brain neurons. NeuroReport 3, 885-888.
    • (1992) NeuroReport , vol.3 , pp. 885-888
    • Knusel, B.1    Rabin, S.2    Swidmer, H.R.3    Hefti, R.4    Kaplan, D.R.5
  • 27
    • 0023846412 scopus 로고
    • Developmental changes in NGF levels in sympathetic ganglia and their target organs
    • Korsching S. and Thoenen H. (1988). Developmental changes in NGF levels in sympathetic ganglia and their target organs. Devl Biol. 126, 40-46.
    • (1988) Devl Biol. , vol.126 , pp. 40-46
    • Korsching, S.1    Thoenen, H.2
  • 28
    • 0013067786 scopus 로고
    • The nerve growth-factor-35 years later
    • Levi-Montalcini R. (1987) The nerve growth-factor-35 years later Eur. molec. Biol. Org. J. 6, 1145-1154.
    • (1987) Eur. Molec. Biol. Org. J. , vol.6 , pp. 1145-1154
    • Levi-Montalcini, R.1
  • 29
    • 0008891919 scopus 로고
    • Phosphate-labelling studies of receptor tyrosine kinases
    • (ed. Hulme, E. C.), IRL Press, Oxford
    • Mahadevan L. C. and Bell J. C. (1991). Phosphate-labelling studies of receptor tyrosine kinases. In Receptors - a Practical Approach, (ed. Hulme, E. C.), pp. 181-201. IRL Press, Oxford.
    • (1991) Receptors - A Practical Approach , pp. 181-201
    • Mahadevan, L.C.1    Bell, J.C.2
  • 30
    • 0027451877 scopus 로고
    • Signal-transduction events mediated by the BDNF receptor gp145(trkb) in primary hippocampal pyramidal cell-culture
    • Marsh H. N., Scholz W. K., Lamballe F., Klein R., Nanduri V., Barbacid M. and Palfrey H. C. (1993) Signal-transduction events mediated by the BDNF receptor gp145(trkb) in primary hippocampal pyramidal cell-culture. J. Neurosci. 13, 4281-4292.
    • (1993) J. Neurosci. , vol.13 , pp. 4281-4292
    • Marsh, H.N.1    Scholz, W.K.2    Lamballe, F.3    Klein, R.4    Nanduri, V.5    Barbacid, M.6    Palfrey, H.C.7
  • 31
    • 0023851503 scopus 로고
    • Inhibitors of protein synthesis and RNA synthesis prevent neuronal cell death caused by nerve growth factor deprivation
    • Martin D. P., Schmidt R. E., DiStefano P. S., Lowry O. H., Carter J. G. and Johnson E. M. Jr (1988) Inhibitors of protein synthesis and RNA synthesis prevent neuronal cell death caused by nerve growth factor deprivation. J. Cell Biol. 106, 829-844.
    • (1988) J. Cell Biol. , vol.106 , pp. 829-844
    • Martin, D.P.1    Schmidt, R.E.2    DiStefano, P.S.3    Lowry, O.H.4    Carter, J.G.5    Johnson E.M., Jr.6
  • 32
    • 0025323817 scopus 로고
    • Expression of the trk proto-oncogene is restricted to the sensory cranial and spinal ganglia of neural crest origin in mouse development
    • Martin-Zanca D., Barbacid M. and Parada L. F. (1990) Expression of the trk proto-oncogene is restricted to the sensory cranial and spinal ganglia of neural crest origin in mouse development. Genes Dev. 4, 683-694.
    • (1990) Genes Dev. , vol.4 , pp. 683-694
    • Martin-Zanca, D.1    Barbacid, M.2    Parada, L.F.3
  • 33
    • 0026098610 scopus 로고
    • Molecular investigations on the high-affinity nerve growth factor receptor
    • Meakin S. O. and Shooter E. M. (1991) Molecular investigations on the high-affinity nerve growth factor receptor. Neuron 6, 153-163.
    • (1991) Neuron , vol.6 , pp. 153-163
    • Meakin, S.O.1    Shooter, E.M.2
  • 34
    • 0024583685 scopus 로고
    • Scrape loading of Swiss 3T3 cells with ras protein rapidly activates protein kinase C in the absence of phosphatidylinositol hydrolysis
    • Morris J. D., Price B., Lloyd A. C., Self A. J., Marshall C. J. and Hall A. (1989) Scrape loading of Swiss 3T3 cells with ras protein rapidly activates protein kinase C in the absence of phosphatidylinositol hydrolysis. Oncogene 4, 27-35.
    • (1989) Oncogene , vol.4 , pp. 27-35
    • Morris, J.D.1    Price, B.2    Lloyd, A.C.3    Self, A.J.4    Marshall, C.J.5    Hall, A.6
  • 35
    • 0027331561 scopus 로고
    • Activation of p21(ras) by nerve growth-factor in embryonic sensory neurons and PC12 cells
    • Ng N. F. L. and Shooter E. M. (1993) Activation of p21(ras) by nerve growth-factor in embryonic sensory neurons and PC12 cells. J. biol. Chem. 268, 25,329-25,333.
    • (1993) J. Biol. Chem. , vol.268 , pp. 25329-25333
    • Ng, N.F.L.1    Shooter, E.M.2
  • 36
    • 0025909606 scopus 로고
    • Mediators of nerve growth factor action in cultured rat superior cervical ganglion neurons
    • Nobes C. D., Buckmaster A. E. and Tolkovsky A. M. (1991) Mediators of nerve growth factor action in cultured rat superior cervical ganglion neurons. J. auton. nerv. Syst. 33, 213-214.
    • (1991) J. Auton. Nerv. Syst. , vol.33 , pp. 213-214
    • Nobes, C.D.1    Buckmaster, A.E.2    Tolkovsky, A.M.3
  • 37
    • 0028985259 scopus 로고
    • Neutralising anti-p21ras Fabs suppress rat sympathetic neuron survival induced by NGF, LIF, CNTF and cAMP
    • Nobes C. D. and Tolkovsky A. M. (1995) Neutralising Anti-p21ras Fabs suppress rat sympathetic neuron survival induced by NGF, LIF, CNTF and cAMP. Eur. J. Neurosci. 7, 344-350.
    • (1995) Eur. J. Neurosci. , vol.7 , pp. 344-350
    • Nobes, C.D.1    Tolkovsky, A.M.2
  • 39
    • 0026684676 scopus 로고
    • Inhibition of cellular actions of nerve growth factor by staurosporine and K252A results from the attenuation of the activity of trk tyrosine kinase
    • Ohmichi M., Decker S. J., Pang L. and Saltiel A. R. (1992) Inhibition of cellular actions of nerve growth factor by staurosporine and K252A results from the attenuation of the activity of trk tyrosine kinase. Biochemistry 31, 4034-4039.
    • (1992) Biochemistry , vol.31 , pp. 4034-4039
    • Ohmichi, M.1    Decker, S.J.2    Pang, L.3    Saltiel, A.R.4
  • 40
    • 0026058318 scopus 로고
    • Cell death during development of the nervous system
    • Oppenheim R. (1991) Cell death during development of the nervous system. A. Rev. Neurosci. 14, 453-501.
    • (1991) A. Rev. Neurosci. , vol.14 , pp. 453-501
    • Oppenheim, R.1
  • 41
    • 0025075302 scopus 로고
    • Effect of a dominant inhibitory Ha ras mutation on neuronal differentiation of PC12 cells
    • Szeberènyi J., Cai H. and Cooper G. M. (1990) Effect of a dominant inhibitory Ha ras mutation on neuronal differentiation of PC12 cells. Molec. Cell. Biol. 10, 5324-5332.
    • (1990) Molec. Cell. Biol. , vol.10 , pp. 5324-5332
    • Szeberènyi, J.1    Cai, H.2    Cooper, G.M.3
  • 43
    • 0023604947 scopus 로고
    • Adenosine 5′-triphosphale synthesis and metabolism localised in neurites of cultured sympathetic neurons
    • Tolkovsky A. M. and Suidan H. S. (1988) Adenosine 5′-triphosphale synthesis and metabolism localised in neurites of cultured sympathetic neurons. Neuroscience 23, 1133-1142.
    • (1988) Neuroscience , vol.23 , pp. 1133-1142
    • Tolkovsky, A.M.1    Suidan, H.S.2
  • 44
    • 0028561983 scopus 로고
    • Neurotrophins regulate sequential-changes in neurotrophin receptor expression by sympathetic neuroblasts
    • Verdi J. M. and Anderson D. J. (1994) Neurotrophins regulate sequential-changes in neurotrophin receptor expression by sympathetic neuroblasts. Neuron 13, 1359-1372.
    • (1994) Neuron , vol.13 , pp. 1359-1372
    • Verdi, J.M.1    Anderson, D.J.2
  • 47
    • 0020627495 scopus 로고
    • Developmental neuron death in the rat superior cervical ganglion: Cell counts and ultrastructure
    • Wright L. L., Cunningham T. J. and Smolen A. J. (1983). Developmental neuron death in the rat superior cervical ganglion: cell counts and ultrastructure. J. Neurocytol. 12, 727-738.
    • (1983) J. Neurocytol. , vol.12 , pp. 727-738
    • Wright, L.L.1    Cunningham, T.J.2    Smolen, A.J.3
  • 48
  • 49
    • 0025177034 scopus 로고
    • Oncogenic activation of the human trk proto-oncogene by recombination with the ribosomal large subunit protein L7a
    • Ziemiecki A., Miller R. G., Xiao-Chang F., Hynes N. E. and Kozma S. (1990) Oncogenic activation of the human trk proto-oncogene by recombination with the ribosomal large subunit protein L7a. Eur. molec. Biol. Org. J. 9, 191-196.
    • (1990) Eur. Molec. Biol. Org. J. , vol.9 , pp. 191-196
    • Ziemiecki, A.1    Miller, R.G.2    Xiao-Chang, F.3    Hynes, N.E.4    Kozma, S.5


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