Targeting molecular signals in chk1 pathways as a new approach for overcoming drug resistance

Cancer and Metastasis Reviews

Volumn 20, Issue 1-2, 2001, Pages 109-115

  Hapke, Gunnar ^a   Yin, Ming Biao ^a   Rustum, Youcef M ^a  

^a ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

cdc25C; Chk1; DNA damage checkpoint; Mismatch repair; p73

Indexed keywords

5 (4,6 DIMETHYL 1,3,2 DIOXAPHOSPHORINAN 2 YL) 2,6 DIMETHYL 4 (3 NITROPHENYL) 3 PYRIDINECARBOXYLIC ACID 2 (4 BENZHYDRYL 1 PIPERAZINYL)ETHYL ESTER P OXIDE; 7 ETHYL 10 HYDROXYCAMPTOTHECIN; 7 HYDROXYSTAUROSPORINE; ANTINEOPLASTIC AGENT; CALCIUM CHANNEL BLOCKING AGENT; CELL CYCLE PROTEIN; CHECKPOINT KINASE 1; CYCLOSPORIN A; DNA TOPOISOMERASE INHIBITOR; DOXORUBICIN; FLUOROURACIL; KARENITECIN; PACLITAXEL; PROTEIN P73; PYRIDINE DERIVATIVE; RALTITREXED; RO 44 5912; TAMOXIFEN; UNCLASSIFIED DRUG; VALSPODAR; VERAPAMIL;

APOPTOSIS; ARTICLE; CANCER; CANCER CHEMOTHERAPY; CELL CYCLE; CELL DEATH; DNA DAMAGE; DRUG ACCUMULATION; DRUG RETENTION; DRUG SENSITIVITY; HUMAN; HUMAN CELL; MISMATCH REPAIR; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANTINEOPLASTIC AGENTS; DRUG RESISTANCE, NEOPLASM; ENZYME INHIBITORS; HUMANS; NEOPLASMS; PROTEIN KINASE INHIBITORS; PROTEIN KINASES;

EID: 0035692492     PISSN: 01677659     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1013116826788     Document Type: Article

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