-
1
-
-
0028198383
-
Identification and characterization of new elements involved in checkpoints and feedback controls in fission yeast
-
al-Khodairy F, Fotou E, Sheldrick KS, Griffiths DJ, Lehmann AR and Carr AM (1994) Identification and characterization of new elements involved in checkpoints and feedback controls in fission yeast. Mol Biol Cell 5:147-160.
-
(1994)
Mol Biol Cell
, vol.5
, pp. 147-160
-
-
Al-Khodairy, F.1
Fotou, E.2
Sheldrick, K.S.3
Griffiths, D.J.4
Lehmann, A.R.5
Carr, A.M.6
-
2
-
-
0023807621
-
Camptothecin, a specific inhibitor of type I DNA topoisomerase, induces DNA breakage at replication fork
-
Avemann K, Knippers R, Koller T and Sogo JM (1988) Camptothecin, a specific inhibitor of type I DNA topoisomerase, induces DNA breakage at replication fork. Mol Cell Biol 8:3026-3034.
-
(1988)
Mol Cell Biol
, vol.8
, pp. 3026-3034
-
-
Avemann, K.1
Knippers, R.2
Koller, T.3
Sogo, J.M.4
-
3
-
-
0028174984
-
DNA topoisomerases: Essential enzymes and lethal targets
-
Chen AY and Liu LF (1994) DNA topoisomerases: Essential enzymes and lethal targets. Annu Rev Pharmacol Toxicol 34:191-218.
-
(1994)
Annu Rev Pharmacol Toxicol
, vol.34
, pp. 191-218
-
-
Chen, A.Y.1
Liu, L.F.2
-
4
-
-
0033558882
-
Association of chk1 with 14-3-3 proteins in stimulated by DNA damage
-
Chen L, Liu TH and Walworth NC (1999) Association of chk1 with 14-3-3 proteins in stimulated by DNA damage. Genes Dev 13:675-685.
-
(1999)
Genes Dev
, vol.13
, pp. 675-685
-
-
Chen, L.1
Liu, T.H.2
Walworth, N.C.3
-
5
-
-
0030055094
-
Current perspectives on camptothecins in cancer treatment
-
Dancey J and Eisenhauer EA (1996) Current perspectives on camptothecins in cancer treatment (Editorial). Br J Cancer 74:327-338.
-
(1996)
Br J Cancer
, vol.74
, pp. 327-338
-
-
Dancey, J.1
Eisenhauer, E.A.2
-
6
-
-
0030768948
-
Cdc25 mitotic inducer targeted by chk1 DNA damage checkpoint kinase
-
Furnari B, Rhind N and Russell P (1997) Cdc25 mitotic inducer targeted by chk1 DNA damage checkpoint kinase. Science (Wash DC) 277:1495-1497.
-
(1997)
Science (Wash DC)
, vol.277
, pp. 1495-1497
-
-
Furnari, B.1
Rhind, N.2
Russell, P.3
-
7
-
-
0025736675
-
Biochemical evidence for two different mechanisms for bleomycin-induced cell killing
-
Giaccia AJ, Shieh J, Cholon A and Brown JM (1991) Biochemical evidence for two different mechanisms for bleomycin-induced cell killing. Mutat Res 263:69-75.
-
(1991)
Mutat Res
, vol.263
, pp. 69-75
-
-
Giaccia, A.J.1
Shieh, J.2
Cholon, A.3
Brown, J.M.4
-
10
-
-
0024425887
-
Checkpoints: Controls that ensure the order of cell cycle events
-
Hartwell LH and Weinert T (1989) Checkpoints: Controls that ensure the order of cell cycle events. Science (Wash DC) 246:629-634.
-
(1989)
Science (Wash DC)
, vol.246
, pp. 629-634
-
-
Hartwell, L.H.1
Weinert, T.2
-
11
-
-
0004406005
-
Karenitecins: New preclinical developments with BNP1350, a novel, potent highly lipophilic camptothecin
-
Hausheer FH, Cao S, Kanter P, Haridas K, Zhao M, Murali D, Seetharamulu P, Yao S, Reddy D, Pavankumar P, Saxe J, Huang Q, Chen X, Parker A, Wu M, Martinez N and Rustum YM (1999) Karenitecins: New preclinical developments with BNP1350, a novel, potent highly lipophilic camptothecin. Proc Am Assoc Cancer Res 40:111.
-
(1999)
Proc Am Assoc Cancer Res
, vol.40
, pp. 111
-
-
Hausheer, F.H.1
Cao, S.2
Kanter, P.3
Haridas, K.4
Zhao, M.5
Murali, D.6
Seetharamulu, P.7
Yao, S.8
Reddy, D.9
Pavankumar, P.10
Saxe, J.11
Huang, Q.12
Chen, X.13
Parker, A.14
Wu, M.15
Martinez, N.16
Rustum, Y.M.17
-
12
-
-
0024420685
-
Arrest of DNA replication by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin
-
Hsiang YH, Lihou MG and Liu LF (1989) Arrest of DNA replication by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin. Cancer Res 49:5077-5082.
-
(1989)
Cancer Res
, vol.49
, pp. 5077-5082
-
-
Hsiang, Y.H.1
Lihou, M.G.2
Liu, L.F.3
-
13
-
-
0028006314
-
Evaluation of topoisomerase I messenger RNA, protein and catalytic activity in human tumors: Demonstration of tumor-type specificity and implications for cancer chemotherapy
-
Husain I, Mohler JL, Seigler HF and Besterman JM (1994) Evaluation of topoisomerase I messenger RNA, protein and catalytic activity in human tumors: Demonstration of tumor-type specificity and implications for cancer chemotherapy. Cancer Res 54:539-546.
-
(1994)
Cancer Res
, vol.54
, pp. 539-546
-
-
Husain, I.1
Mohler, J.L.2
Seigler, H.F.3
Besterman, J.M.4
-
14
-
-
0028965797
-
Cell cycle checkpoints and DNA repair preserve the stability of the human genome
-
Kaufmann WK (1995) Cell cycle checkpoints and DNA repair preserve the stability of the human genome. Cancer Metastasis Rev 14:31-41.
-
(1995)
Cancer Metastasis Rev
, vol.14
, pp. 31-41
-
-
Kaufmann, W.K.1
-
16
-
-
0023819810
-
2 block induced by DNA crosslinking agents and its possible consequence
-
2 block induced by DNA crosslinking agents and its possible consequence. Biochem Pharmacol 37:2303-2309.
-
(1988)
Biochem Pharmacol
, vol.37
, pp. 2303-2309
-
-
Konopa, J.1
-
17
-
-
0028064989
-
Down-regulation of c-myc gene expression with induction of high molecular weight DNA fragments by fluorodeoxyuridine
-
Li ZR, Yin MB, Arredondo MA, Schober C and Rustum YM (1994) Down-regulation of c-myc gene expression with induction of high molecular weight DNA fragments by fluorodeoxyuridine. Biochem Pharmacol 48:327-334.
-
(1994)
Biochem Pharmacol
, vol.48
, pp. 327-334
-
-
Li, Z.R.1
Yin, M.B.2
Arredondo, M.A.3
Schober, C.4
Rustum, Y.M.5
-
18
-
-
0024316466
-
DNA topoisomerase poisons as antitumor drugs
-
Liu LF (1989) DNA topoisomerase poisons as antitumor drugs. Annu Rev Biochem 58:351-375.
-
(1989)
Annu Rev Biochem
, vol.58
, pp. 351-375
-
-
Liu, L.F.1
-
19
-
-
0033552943
-
Nuclear localization of cdc25 is regulated by DNA damage and a 14-3-3 protein
-
Lopez-Girona A, Furnari B, Mondesert O and Russell P (1999) Nuclear localization of cdc25 is regulated by DNA damage and a 14-3-3 protein. Nature (Lond) 397: 172-175.
-
(1999)
Nature (Lond)
, vol.397
, pp. 172-175
-
-
Lopez-Girona, A.1
Furnari, B.2
Mondesert, O.3
Russell, P.4
-
20
-
-
0028932603
-
Cell cycle regulation in response to DNA damage in mammalian cells: A historical perspective
-
Murnane JP (1995) Cell cycle regulation in response to DNA damage in mammalian cells: A historical perspective. Cancer Metastasis Rev 14:17-29.
-
(1995)
Cancer Metastasis Rev
, vol.14
, pp. 17-29
-
-
Murnane, J.P.1
-
22
-
-
0027029077
-
A fundamental role for cell cycle regulation in the chemosensitivity of cancer cells
-
O'Connor PM and Kohn KW (1992) A fundamental role for cell cycle regulation in the chemosensitivity of cancer cells. Semin Cancer Biol 3:409-416.
-
(1992)
Semin Cancer Biol
, vol.3
, pp. 409-416
-
-
O'Connor, P.M.1
Kohn, K.W.2
-
23
-
-
0029026611
-
Contrasting patterns of DNA fragmentation induced by thymidylate synthase inhibitors, ZD1694 and AG-331
-
Panadero A, Yin MB, Voigt W and Rustum YM (1995) Contrasting patterns of DNA fragmentation induced by thymidylate synthase inhibitors, ZD1694 and AG-331. Oncol Res 7:73-81.
-
(1995)
Oncol Res
, vol.7
, pp. 73-81
-
-
Panadero, A.1
Yin, M.B.2
Voigt, W.3
Rustum, Y.M.4
-
24
-
-
0029085781
-
A checkpoint regulates the rate of progression through S phase in S. cerevisiae in response to DNA damage
-
Paulovich AG and Hartwell LH (1995) A checkpoint regulates the rate of progression through S phase in S. cerevisiae in response to DNA damage. Cell 82:841-847.
-
(1995)
Cell
, vol.82
, pp. 841-847
-
-
Paulovich, A.G.1
Hartwell, L.H.2
-
25
-
-
0033118909
-
The ATM protein is required for sustained activation of NF-κB following DNA damage
-
Piret B, Schoonbroodt S and Piette J (1999) The ATM protein is required for sustained activation of NF-κB following DNA damage. Oncogene 18:2261-2271.
-
(1999)
Oncogene
, vol.18
, pp. 2261-2271
-
-
Piret, B.1
Schoonbroodt, S.2
Piette, J.3
-
26
-
-
0029960812
-
Eukaryotic DNA topoisomerase I: Genome gate keeper and its intruders, camptothecins
-
Pommier Y (1996) Eukaryotic DNA topoisomerase I: Genome gate keeper and its intruders, camptothecins. Semin Oncol 23:3-10.
-
(1996)
Semin Oncol
, vol.23
, pp. 3-10
-
-
Pommier, Y.1
-
27
-
-
0028033906
-
Cellular determinants of sensitivity and resistance to DNA topoisomerase inhibitors
-
Pommier Y, Leteurtre F, Fesen MR, Fujimon A, Bertrand R, Solary E, Kohlhagen G and Kohn KW (1994) Cellular determinants of sensitivity and resistance to DNA topoisomerase inhibitors. Cancer Invest 12:530-542.
-
(1994)
Cancer Invest
, vol.12
, pp. 530-542
-
-
Pommier, Y.1
Leteurtre, F.2
Fesen, M.R.3
Fujimon, A.4
Bertrand, R.5
Solary, E.6
Kohlhagen, G.7
Kohn, K.W.8
-
28
-
-
0028267240
-
Camptothecins: From bench research to hospital wards
-
Potmesil M (1994) Camptothecins: From bench research to hospital wards. Cancer Res 54:1431-1439.
-
(1994)
Cancer Res
, vol.54
, pp. 1431-1439
-
-
Potmesil, M.1
-
29
-
-
0019326566
-
2 arrest in mammalian cells
-
2 arrest in mammalian cells. Mol Cell Biochem 29:47-57.
-
(1980)
Mol Cell Biochem
, vol.29
, pp. 47-57
-
-
Rao, P.N.1
-
30
-
-
0003913160
-
Inhibition of the human checkpoint kinase, chk1, abrogates G2/M arrest in response to DNA damage
-
Roshak A, Gilmartin A, Imburgia C, Marshall LA and Jackson JR (1999) Inhibition of the human checkpoint kinase, chk1, abrogates G2/M arrest in response to DNA damage. Proc Am Assoc Cancer Res 40:413-414.
-
(1999)
Proc Am Assoc Cancer Res
, vol.40
, pp. 413-414
-
-
Roshak, A.1
Gilmartin, A.2
Imburgia, C.3
Marshall, L.A.4
Jackson, J.R.5
-
31
-
-
0025812689
-
Camptothecin cytotoxicity in mammalian cells is associated with the induction of persistent double strand breaks in replicating DNA
-
Ryan AJ, Squires S, Strutt HL and Johnson RT (1991) Camptothecin cytotoxicity in mammalian cells is associated with the induction of persistent double strand breaks in replicating DNA. Nucleic Acids Res 19:3295-3300.
-
(1991)
Nucleic Acids Res
, vol.19
, pp. 3295-3300
-
-
Ryan, A.J.1
Squires, S.2
Strutt, H.L.3
Johnson, R.T.4
-
32
-
-
0021153574
-
Separation of yeast chromosome-sized DNAs by pulsed field gradient gel electrophoresis
-
Schwartz DC and Cantor CR (1984) Separation of yeast chromosome-sized DNAs by pulsed field gradient gel electrophoresis. Cell 37:67-75.
-
(1984)
Cell
, vol.37
, pp. 67-75
-
-
Schwartz, D.C.1
Cantor, C.R.2
-
33
-
-
0025341331
-
New colorimetric cytotoxicity assay for anticancer-drug screening
-
Skehan P, Storeng R, Scudiero D, Monks A, McMahon J, Vistica D, Warren JT, Bokesch H, Kenney S and Boyd MR (1990) New colorimetric cytotoxicity assay for anticancer-drug screening. J Natl Cancer Inst 28:1107-1112.
-
(1990)
J Natl Cancer Inst
, vol.28
, pp. 1107-1112
-
-
Skehan, P.1
Storeng, R.2
Scudiero, D.3
Monks, A.4
McMahon, J.5
Vistica, D.6
Warren, J.T.7
Bokesch, H.8
Kenney, S.9
Boyd, M.R.10
-
34
-
-
0027425599
-
Activity and expression pattern of cyclin-dependent kinase 5 in the embryonic mouse nervous system
-
Tsai LH, Takahashi T, Caviness VS Jr and Harlow E (1993) Activity and expression pattern of cyclin-dependent kinase 5 in the embryonic mouse nervous system. Development 119:1029-1040.
-
(1993)
Development
, vol.119
, pp. 1029-1040
-
-
Tsai, L.H.1
Takahashi, T.2
Caviness V.S., Jr.3
Harlow, E.4
-
35
-
-
0026625512
-
2 arrest: Altered regulation of p34cdc2/cyclin B
-
2 arrest: Altered regulation of p34cdc2/cyclin B. Cancer Res 52:1823-1829.
-
(1992)
Cancer Res
, vol.52
, pp. 1823-1829
-
-
Tsao, Y.P.1
D'Arpa, P.2
Liu, L.F.3
-
36
-
-
0029664616
-
Rad-dependent response of the chk1-encoded protein kinase at the DNA damage checkpoint
-
Walworth NC and Bernards R (1996) Rad-dependent response of the chk1-encoded protein kinase at the DNA damage checkpoint. Science (Wash DC) 271:353-356.
-
(1996)
Science (Wash DC)
, vol.271
, pp. 353-356
-
-
Walworth, N.C.1
Bernards, R.2
-
37
-
-
0032773824
-
The topoisomerase I poison camptothecin generates a chk1-dependent DNA-damage checkpoint signal in fission yeast
-
Wan S, Capasso H and Walworth NC (1999) The topoisomerase I poison camptothecin generates a chk1-dependent DNA-damage checkpoint signal in fission yeast. Yeast 15:821-828.
-
(1999)
Yeast
, vol.15
, pp. 821-828
-
-
Wan, S.1
Capasso, H.2
Walworth, N.C.3
-
38
-
-
0033602038
-
Cyclin E-cdk2 activation is associated with cell cycle arrest and inhibition of DNA replication induced by the thymidylate synthase inhibitor Tomudex
-
Yin MB, Guo B, Panadero A, Frank C, Wrzosek C, Slocum HK and Rustum YM (1999) Cyclin E-cdk2 activation is associated with cell cycle arrest and inhibition of DNA replication induced by the thymidylate synthase inhibitor Tomudex. Exp Cell Res 247:189-199.
-
(1999)
Exp Cell Res
, vol.247
, pp. 189-199
-
-
Yin, M.B.1
Guo, B.2
Panadero, A.3
Frank, C.4
Wrzosek, C.5
Slocum, H.K.6
Rustum, Y.M.7
-
39
-
-
0029127643
-
ATM-related genes: What do they tell us about functions of the human gene?
-
Zakian VA (1995) ATM-related genes: What do they tell us about functions of the human gene? Cell 82:685-687.
-
(1995)
Cell
, vol.82
, pp. 685-687
-
-
Zakian, V.A.1
|