Mismatch repair, molecular switches, and signal transduction

Genes and Development

Volumn 12, Issue 14, 1998, Pages 2096-2101

  Fishel, Richard ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; DNA; GENE PRODUCT; GUANINE NUCLEOTIDE BINDING PROTEIN; NUCLEOTIDE;

BASE MISPAIRING; BIOCHEMISTRY; DNA METABOLISM; DNA REPAIR; MOLECULAR BIOLOGY; ON OFF PHENOMENON; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; THERMODYNAMICS;

EID: 0032527704     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.12.14.2096     Document Type: Review

References (56)

1. Acharya, S., T. Wilson, S. Gradia, M.F. Kane, S. Guerrette, G.T. Marsischky, R. Kolodner, and R. Fishel. 1996. hMSH2 forms specific mispair-binding complexes with HMSH3 and hMSH6. Proc. Natl. Acad. Sci. 93,: 13629-13634.
2. Alani, E., T. Sokolsky, B. Studamire, J.J. Miret, and R.S. Lahue. 1997. Genetic and biochemical analysis of Msh2p-Msh6p: Role of ATP hydrolysis and Msh2p-Msh6p subunit interactions in mismatch base pair recognition. Mol. Cell. Biol. 17: 2436-2447.
3. Alberts, B. 1998. The cell as a collection of protein machines -preparing the next generation of molecular biologists. Cell 92: 291-294.
4. Allen, D.J., A. Makhov, M. Grilley, J. Taylor, R. Thresher, P. Modrich, and J.D. Griffith. 1997. MutS mediates heteroduplex loop formation by a translocation mechanism. EMBO J. 16: 4467-4476.
5. Bokoch, G.M. and C.J. Der. 1993. Emerging concepts in the Ras superfamily of GTP-binding proteins. FASEB J. 7: 750-759.
6. Bronner, C.E., S.M. Baker, P.T. Morrison, G. Warren, L.G. Smith, M.K. Lescoe, M. Kane, C. Earabino, J. Lipford, A. Lindblom et al. 1994. Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer. Nature 368: 258-261.
7. Burns, N., B. Grimwade, P.B. Ross-Macdonald, E. Choi, K. Finberg, G.S. Roeder, and M.S. Snyder. 1994. Large-scale analysis of gene expression, protein localization and gene disruption in Saccharomyces cerevisiae. Genes & Dev. 8: 1087-1105.
8. Campbell, J.L. and N. Kleckner. 1990. E. coli oriC and the dnaA gene promoter are sequestered from dam methyltransferase following the passage of the chromosomal replication fork. Cell 62: 967-979.
9. Chi, N.W. and R.D. Kolodner. 1994. Purification and characterization of MSH1, a yeast mitochondrial protein that binds to DNA mismatches. J. Biol. Chem. 269: 29984-29992.
10. Cooper, D.L., R.S. Lahue, and P. Modrich. 1993. Methyl-directed mismatch repair is bidirectional. J. Biol. Chem. 268: 11823-11829.
11. Demerec, M., E.L. Lahr, T. Miyake, E. Galehran, E. Balbinder, S. Baric, K. Hashimoto, E.V. Glanville, and J.D. Gross. 1957. Bacterial genetics. Carnegie Inst. Wash. Yearbook 370: 390-406.
12. Dohlman, H.G. and J. Thorner. 1997. RGS proteins and signaling by heterotrimeric G proteins. J. Biol. Chem. 272: 3871-3874.
13. Drummond, J.T., G.-M. Li, M.J. Longley, and P. Modrich. 1995. Isolation of an hMSH2-p160 heterodimer that restores DNA mismatch repair to tumor cells. Science 268: 1909-1912.
14. Fishel, R., A. Ewel, S. Lee, M.K. Lescoe, and J. Griffith. 1994. Binding of mismatched microsatellite DNA sequences by the human MSH2 protein. Science 266: 1403-1405.
15. Fishel, R., M.K. Lescoe, M.R. Rao, N.G. Copeland, N.A. Jenkins, J. Garber, M. Kane, and R. Kolodner. 1993. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell 75: 1027-1038.
16. Fishel, R. and T. Wilson. 1997. MutS homologs in mammalian cells. Curr. Opin. Genet. Dev. 7: 105-113.
17. Fishel, R.A. and R. Kolodner. 1983. Gene conversion in Escherichia coli: The identification of two repair pathways for mismatched nucleotides. UCLA Symp. Mol. Cell. Biol. New Ser. 11: 309-324.
18. Fishel, R.A., E.C. Siegel, and R. Kolodner. 1986. Gene conversion in Escherichia coli. Resolution of heteroallelic mismatched nucleotides by co-repair. J. Mol. Biol. 188: 147-157.
19. Friedberg, E.C. 1990. DNA repair W.H. Freeman, New York, NY.
20. Fujii, H. and T. Shimada. 1989. Isolation and characterization of cDNA clones derived from the divergently transcribed gene in the region upstream from the human dihydrofolate reductase gene. J. Biol. Chem. 264: 10057-10064.
21. Gradia S., S. Acharya, and R. Fishel. 1997. The human mismatch recognition complex hMSH2-hMSH6 functions as a novel molecular switch. Cell 91: 995-1005.
22. Grilley, M., K.M. Welsh, S.S. Su, and P. Modrich. 1989. Isolation and characterization of the Escherichia coli mutL gene product. J. Biol. Chem. 264: 1000-1004.
23. Haber, L.T. and G.C. Walker. 1991. Altering the conserved nucleotide binding motif in the Salmonella typhimurium MutS mismatch repair protein affects both its ATPase an mismatch binding activities. EMBO J. 10: 2707-2715.
24. Harris, R.S., K.J. Ross, M.J. Lombardo, and S.M. Rosenberg. 1998. Mismatch repair in Escherichia coli cells lacking single-strand exonucleases ExoI, ExoVII, and RecJ. J. Bacteriol. 180:989-993.
25. Hill, R.F. 1970. Location of genes controlling excision repair of UV damage and mutator activity in Escherichia coli WP2. Mutat. Res. 9: 341-344.
26. Holliday, R.A. 1964. A mechanism for gene conversion in fungi. Genet. Res. 5: 282-304.
27. Hollingsworth, N.M., L. Ponte, and C. Halsey. 1995. MSH5, a novel MutS homolog, facilitates meiotic reciprocal recombination between homologs in Saccharomyces cerevisiae but not mismatch repair. Genes & Dev. 9: 1728-1739.
28. Keller, E.B. and P.C. Zamecnik. 1955. The effect of guanosine diphosphate and triphosphate on the incorporation of labeled amino acids into proteins. J. Biol. Chem. 221: 45-59.
29. Kolodner, R. 1996. Biochemistry and genetics of eukaryotic mismatch repair. Genes & Dev. 10: 1433-1442.
30. Kramer, W., B. Kramer, M.S. Williamson, and S. Fogel. 1989. Cloning and nucleotide sequence of DNA mismatch repair gene PMS1 from Saccharomyces cerevisiae: Homology of PMS1 to procaryotic MutL and HexB. J. Bacteriol. 171: 5339-5346.
31. Lahue, R.S., K.G. Au, and P. Modrich. 1989. DNA mismatch correction in a defined system. Science 245: 160-164.
32. Linton, J.P., J.Y. Yen, E. Selby, Z. Chen, J.M. Chinsky, K. Liu, R.E. Kellems, and G.F. Crouse. 1989. Dual bidirectional promoters at the mouse dhfr locus: Cloning and characterization of two mRNA classes of the divergently transcribed Rep-1 gene. Mol. Cell. Biol. 9: 3058-3072.
33. Lu, A.L., S. Clark, and P. Modrich. 1983. Methyl-directed repair of DNA base-pair mismatches in vitro. Proc. Natl. Acad. Sci. 80: 4639-4643.
34. Mankovich, J.A., C.A. McIntyre, and G.C. Walker. 1989. Nucleotide sequence of the Salmonella typhimurium mutL gene required for mismatch repair: Homology of MutL to HexB of Streptococcus pneumoniae and to PMS1 of the yeast Saccharomyces cerevisiae. J. Bacteriol. 171: 5325-5331.
35. Marsischky, G.T., N. Filosi, M.F. Kane, and R. Kolodner. 1996. Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair. Genes & Dev. 10: 407-420.
36. Miyake, T. 1960. Mutator factor in Salmonella typhimurium. Genetics 45: 755-762.
37. Modrich, P. 1989. Methyl-directed DNA mismatch correction. J. Biol. Chem. 264: 6597-6600.
38. _. 1997. Strand-specific mismatch repair in mammalian cells. J. Biol. Chem. 272: 24727-24730.
39. Modrich, P. and R. Lahue. 1996. Mismatch repair in replication fidelity, genetic recombination, and cancer biology. Annu. Rev. Biochem. 65: 101-133.
40. Nathans, D., G. Von Ehrenstein, R. Monro, and F. Lipmann. 1962. Protein synthesis from aminoacyl-soluble ribonucleic acid. Fed. Proc. 21: 127-133.
41. New, L., K. Liu, and G.F. Crouse. 1993. The yeast gene MSH3 defines a new class of eukaryotic MutS homologues. Mol. & Gen. Genet. 239: 97-108.
42. Nicolaides, N.C., N. Papadopoulos, B. Liu, Y.F. Wei, K.C. Carter, S.M. Ruben, C.A. Rosen, W.A. Haseltine, R.D. Fleischmann, C.M. Fraser et al. 1994. Mutations of two PMS homologues in hereditary nonpolyposis colon cancer. Nature 371: 75-80.
43. Palombo, F., P. Gallinari, I. Iaccarino, T. Lettieri, M. Hughes, A. D'Arrigo, O. Truong, J.J. Hsuan, and J. Jiricny. 1995. GTBP, a 160-kilodalton protein essential for mismatch binding activity in human cells. Science 268: 1912-1914.
44. Prolla, T.A., D.-M. Christie, and R.M. Liskay. 1994. A requirement in yeast DNA mismatch repair for MIH1 and PMS1, two homologs of the bacterial mutL gene. Mol. Cell. Biol. 14: 407-415.
45. Quilliam, L.A., R. Khosravi Far, S.Y. Huff, and C.J. Der. 1995. Guanine nucleotide exchange factors: Activators of the Ras superfamily of proteins. BioEssays 17: 395-404.
46. Reenan, R.A.G. and R.D. Kolodner. 1992. Isolation and characterization of two Saccharomyces cerevisiae genes encoding homologs of the bacterial HexA and MutS mismatch repair proteins. Genetics 132: 963-973.
47. Siegel, E.C. and V. Bryson. 1967. Mutator gene of Escherichia coli Brit. J. Bacteriol. 94: 38-47.
48. Song, L. and K.L. Magleby. 1994. Testing for microscopic reversibility in the gating of maxi K+ channels using two-dimensional dwell-time distributions [published erratum appears in Biophys. J. 1994 Oct; 67(4):1792]. Biophy. J. 67: 91-104.
49. Sprang, S.R. 1997. G protein mechanisms: Insights from structural analysis. Annu. Rev. Biochem. 66: 639-678.
50. Su, S.-S. and P. Modrich. 1986. Escherichia coli mutS-encoded protein binds to mismatched DNA base pairs. Proc. Natl. Acad. Sci. 83: 5057-5061.
51. Tocque, B., I. Delumeau, F. Parker, F. Maurier, M.C. Multon, and F. Schweighoffer. 1997. Ras-GTPase activating protein (GAP): A putative effector for Ras. Cell Signal 9: 153-158.
52. Trahey, M. and F. McCormick. 1987. A cytoplasmic protein stimulates normal N-ras p21 GTPase, but does not affect oncogenic mutants. Science 238: 542-545.
53. Trahey, M., R.J. Milley, G.E. Cole, M. Innis, H. Paterson, C.J. Marshall, A. Hall, and F. McCormick. 1987. Biochemical and biological properties of the human N-ras p21 protein. Mol. Cell. Biol. 7: 541-544.
54. Walker, J.E., M. Saraste, M.J. Runswick, and N.G. Gay. 1982. Distantly related sequences in the alpha-and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold. EMBO J. 1: 945-951.
55. Welsh, K.M., A.L. Lu, S. Clark, and P. Modrich. 1987. Isolation and characterization of the Escherichia coli mutH gene product. J. Biol. Chem. 262: 15624-15629.
56. Weinberg, R.A. 1989. Oncogenes, antioncogenes, and the molecular basis of multistep carcinogenesis. Cancer Res. 49: 3713-3721.