Abnormal chemokine-induced responses of immature and mature hematopoietic cells from motheaten mice implicate the protein tyrosine phosphatase SHP-1 in chemokine responses

Journal of Experimental Medicine

Volumn 190, Issue 5, 1999, Pages 681-690

  Kim, Chang H ^a,b,c   Qu, Cheng Kui ^a,b   Hangoc, Giao ^a,b   Cooper, Scott ^a,b   Anzai, Nauyuki ^a,b   Feng, Gen Sheng ^a,b   Broxmeyer, Hal E ^a,b  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WALTHER CANCER INSTITUTE   (United States)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Chemokine; Chemotaxis; Myelosuppression; Src homology 2 domain tyrosine phosphatase 1; Stromal cell derived factor 1; Viable motheaten mice

Indexed keywords

ACTIN; CHEMOKINE; CYTOKINE RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN TYROSINE PHOSPHATASE;

ACTIN POLYMERIZATION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; B LYMPHOCYTE; CELL MATURATION; CELLULAR IMMUNITY; CONTROLLED STUDY; ENZYME ACTIVATION; HEMATOPOIETIC CELL; LEUKOCYTE; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMYELOCYTE; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

ACTINS; ANIMALS; BASE SEQUENCE; BONE MARROW CELLS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL DIVISION; CELL MOVEMENT; CHEMOKINES, CXC; CHEMOTAXIS; DNA PRIMERS; ENZYME ACTIVATION; HEMATOPOIETIC STEM CELLS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; PROTEIN-TYROSINE-PHOSPHATASE; RECEPTORS, CHEMOKINE; SHP1 PROTEIN TYROSINE PHOSPHATASE;

EID: 0032870280     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.190.5.681     Document Type: Article

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