Pharmacologically elevated levels of endogenous kynurenic acid prevent nicotine-induced activation of nigral dopamine neurons

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 363, Issue 1, 2001, Pages 21-27

  Erhardt, S ^a   Oberg H ^a   Engberg, G ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Dopamine; Glutamate; Kynurenic acid; Nicotine; PNU 156561A; Substantia nigra

Indexed keywords

2 AMINO 4 OXO 4 (3' FLUORODICHLOROPHENYL)BUTANOIC ACID; AMINO ACID RECEPTOR BLOCKING AGENT; BUTYRIC ACID DERIVATIVE; DOPAMINE; GLUTAMIC ACID; KYNURENIC ACID; KYNURENINE 3 MONOOXYGENASE; NICOTINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOPAMINERGIC ACTIVITY; ELECTROPHYSIOLOGY; MALE; NERVE CELL MEMBRANE POTENTIAL; NERVE CELL STIMULATION; NEUROTRANSMITTER RELEASE; NONHUMAN; RAT; SUBSTANTIA NIGRA;

ACTION POTENTIALS; ANIMALS; BETA-CYCLODEXTRINS; BUTYRATES; CYCLODEXTRINS; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; KYNURENIC ACID; KYNURENINE 3-MONOOXYGENASE; MALE; MIXED FUNCTION OXYGENASES; NEURONS; NICOTINE; RATS; RATS, SPRAGUE-DAWLEY; SUBSTANTIA NIGRA;

EID: 0035161802     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002100000325     Document Type: Article

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