Novel systemically active antagonists of the glycine site of the N- methyl-D-aspartate receptor: Electrophysiological, biochemical and behavioral characterization

Journal of Pharmacology and Experimental Therapeutics

Volumn 283, Issue 3, 1997, Pages 1264-1275

  Parsons, Chris G ^a   Danysz, Wojciech ^a   Quack, Günter ^a   Hartmann, Sabine ^a   Lorenz, Bianke ^a   Wollenburg, Christine ^a   Baran, Leokadia ^b   Przegalinski, Edmund ^b   Kostowski, Wojciech ^c   Krzascik, Pawel ^c   Chizh, Boris ^d   Headley, P Max ^d  

^a MERZ PHARMACEUTICALS GMBH   (Germany)

^b INSTITUTE OF PHARMACOLOGY   (Poland)

^c INSTITUTE OF PSYCHIATRY AND NEUROLOGY   (Poland)

^d SCHOOL OF MEDICAL SCIENCES   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

1 AMINOCYCLOPROPANECARBOXYLIC ACID; 3 AMINO 1 HYDROXY 2 PYRROLIDINONE; 5,7 DICHLORO 1,2,3,4 TETRAHYDRO 4 (3 PHENYLUREIDO) 2 QUINOLINECARBOXYLIC ACID; 5,7 DICHLOROKYNURENIC ACID; 7 CHLORO 4 HYDROXY 3 (3 PHENOXYPHENYL) 2 QUINOLONE; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; CYCLOSERINE; GLYCINE; GLYCINE RECEPTOR ANTAGONIST; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PENTETRAZOLE; PHTHALAZINE DERIVATIVE; PROBENECID; STRYCHNINE; TETRODOTOXIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR; BLOOD BRAIN BARRIER; BRAIN MEMBRANE; CONTROLLED STUDY; CONVULSION; DRUG ANTAGONISM; DRUG BIOAVAILABILITY; DRUG PENETRATION; DRUG POTENCY; DRUG RECEPTOR BINDING; EMBRYO; FEMALE; INTRAPERITONEAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MALE; MICROELECTRODE; MOUSE; NERVOUS SYSTEM ELECTROPHYSIOLOGY; NONHUMAN; ORAL DRUG ADMINISTRATION; PATCH CLAMP; PRIORITY JOURNAL; RAT; RECEPTOR DOWN REGULATION; SPINAL CORD NERVE CELL; SUBCUTANEOUS DRUG ADMINISTRATION;

ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID; ANIMALS; ANTICONVULSANTS; BEHAVIOR, ANIMAL; EXCITATORY AMINO ACID ANTAGONISTS; INDOLES; MALE; MICE; N-METHYLASPARTATE; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; RECEPTORS, AMPA; RECEPTORS, GLYCINE; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 14444285260     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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