Mutational pattern of the nurse shark antigen receptor gene (NAR) is similar to that of mammalian Ig genes and to spontaneous mutations in evolution: The translesion synthesis model of somatic hypermutation

International Immunology

Volumn 11, Issue 5, 1999, Pages 825-833

  Diaz, Marilyn ^a,b   Velez, Jovanna ^a   Singh, Mallika ^b   Cerny, Jan ^b   Flajnik, Martin F ^a,b  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

DNA polymerase ; Evolution; Mutational pattern; Nurse shark antigen receptor; REV3; Somatic hypermutation

Indexed keywords

DNA GLYCOSYLTRANSFERASE; DNA POLYMERASE; IMMUNOGLOBULIN; IMMUNOGLOBULIN G; LYMPHOCYTE ANTIGEN RECEPTOR;

ARTICLE; BASE PAIRING; EVOLUTION; EXCISION REPAIR; IMMUNOGLOBULIN GENE; MAMMAL; MUTATION RATE; NONHUMAN; PRIORITY JOURNAL; PSEUDOGENE; RECEPTOR GENE; SHARK; SPONTANEOUS MUTATION; YEAST;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; DNA REPAIR; DNA-DIRECTED DNA POLYMERASE; EVOLUTION; FUNGAL PROTEINS; GENES, IMMUNOGLOBULIN; IMMUNOGLOBULINS; MOLECULAR SEQUENCE DATA; MUTATION; RECEPTORS, ANTIGEN; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 0032911308     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/11.5.825     Document Type: Article

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