Topical bicuculline to the rat spinal cord induces highly localized allodynia that is mediated by spinal prostaglandins

Pain

Volumn 92, Issue 3, 2001, Pages 351-361

  Zhang, Zizhen ^a   Hefferan, Michael P ^a   Loomis, Christopher W ^a  

^a MEMORIAL UNIVERSITY OF NEWFOUNDLAND   (Canada)

Author keywords

Allodynia; Bicuculline; Cyclooxygenase; Prostaglandins; Rat; Spinal

Indexed keywords

2 AMINO 7 PHOSPHONOHEPTANOIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; BICUCULLINE METHIODIDE; CYCLOOXYGENASE 2 INHIBITOR; HALOTHANE; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PROSTAGLANDIN; SC 51322; URETHAN;

ALLODYNIA; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE MONITORING; CONTROLLED STUDY; DOSE RESPONSE; ELECTROCORTICOGRAPHY; HAIR; HEART RATE; LAMINECTOMY; MALE; MEAN ARTERIAL PRESSURE; MOTOR ACTIVITY; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; RAT; RECEPTOR BLOCKING; SENSITIZATION; SENSORY NERVE CONDUCTION; SPINAL CORD; TACTILE STIMULATION; WITHDRAWAL REFLEX;

2-AMINO-5-PHOSPHONOVALERATE; ADMINISTRATION, TOPICAL; ANIMALS; BICUCULLINE; BLOOD PRESSURE; CYCLOOXYGENASE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROENCEPHALOGRAPHY; EXCITATORY AMINO ACID ANTAGONISTS; GABA ANTAGONISTS; HEART RATE; MALE; MOTOR NEURONS; NITROBENZENES; PAIN MEASUREMENT; POSTERIOR HORN CELLS; PROSTAGLANDINS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, PROSTAGLANDIN E; SPINAL CORD; SULFONAMIDES; TOUCH;

EID: 0035370875     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3959(01)00276-7     Document Type: Article

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