Biphasic modulation in the trigeminal nociceptive neuronal responses by the intracerebroventricular prostaglandin E2 may be mediated through different EP receptors subtypes in rats

Brain Research

Volumn 771, Issue 2, 1997, Pages 278-284

  Oka, Takakazu ^a   Hori, Tetsuro ^a   Hosoi, Masako ^a   Oka, Kae ^a   Abe, Michie ^a   Kubo, Chiharu ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

17 Phenyl trinor prostaglandin E2; Analgesia; Central nervous system; Hyperalgesia; MB28767; Pain; Prostaglandin E2

Indexed keywords

1 ACETYL 2 (8 CHLORO 10,11 DIHYDRODIBENZ[B,F][1,4]OXAZEPINE 10 CARBONYL)HYDRAZINE; 11 DEOXY 16 PHENOXY 17,18,19,20 TETRANORPROSTAGLANDIN E1; BUTAPROST; PROSTAGLANDIN E2; RECEPTOR SUBTYPE;

ANALGESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DRUG RECEPTOR BINDING; ELECTROPHYSIOLOGY; HYPERALGESIA; HYPOALGESIA; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; NERVE POTENTIAL; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; RAT; TACTILE STIMULATION; TRIGEMINAL NUCLEUS;

ANALGESICS; ANIMALS; DINOPROSTONE; DOSE-RESPONSE RELATIONSHIP, DRUG; INJECTIONS, INTRAVENTRICULAR; MALE; NEURONS, AFFERENT; NOCICEPTORS; PROSTAGLANDIN ANTAGONISTS; RATS; RATS, WISTAR; RECEPTORS, PROSTAGLANDIN E; TRIGEMINAL NUCLEI;

EID: 0030776101     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(97)00802-0     Document Type: Article

References (31)

1. 3 prostanoid receptor. FEBS Lett. 338:1994;170-174.
2. 1 receptor gene. Eur. J. Biochem. 231:1995;809-814.
3. Coleman R.A., Grix S.P., Head S.A., Louttit J.B., Mallett A., Sheldrick R.L.G. A novel inhibitory prostanoid receptor in piglet saphenous vein. Prostaglandins. 47:1994;151-168.
4. Coleman R.A., Smith W.L., Narumiya S. VIII International union of pharmacology classification of prostanoid receptors: properties, distribution, and structure of the receptors and their subtypes. Pharmacol. Rev. 46:1994;205-229.
5. 2. Prostaglandins. 16:1978;31-37.
6. 2 in the brain, Ann. NY Acad. Sci., in press.
7. 2α to conscious mice. Eur. J. Pharmacol. 122:1986;173-179.
8. 3 subtype is involved in thermal hyperalgesia through its action in the preoptic hypothalamus and the diagonal band of Broca in rats, Pain 71 (1997) 303-311.
9. 2-induced hyperalgesia in the rat. Neuroscience. 62:1994;345-350.
10. Khasar S.G., Ouseph A.K., Chou B., Ho T., Green P.G., Levine J.D. Is there more than one prostaglandin E receptor subtype mediating hyperalgesia in the rat hindpaw? Neuroscience. 64:1995;1161-1165.
11. 2-induced enhancement of the bradykinin response of nociceptors. Brain Res. 632:1993;321-324.
12. 2-induced enhancement of the heat response of nociceptors. Neurosci. Lett. 175:1994;71-73.
13. 2 to mice. Br. J. Pharmacol. 112:1994;735-740.
14. Mokha S.S., Goldsmith G.E., Hellon R.F., Puri R. Hypothalamic control of nocireceptive and other neurones in the marginal layer of the dorsal horn of the medulla (trigeminal nucleus caudalis) in the rat. Exp. Brain Res. 65:1987;427-436.
15. 3 determines G-protein specificity. Nature. 365:1993;166-170.
16. 2 from rat hypothalamic explants in vitro. Neuroendocrinology. 56:1992;61-68.
17. 4 subtype. FEBS Lett. 364:1995;339-341.
18. 2-induced hyperalgesia in conscious mice. Brain Res. 677:1995;138-144.
19. 2 on pain and inflammation. Jpn. J. Pharmacol. 33:1983;264-266.
20. Oka T., Aou S., Hori T. Intracerebroventricular injection of interleukin-1β enhances nociceptive neuronal responses of the trigeminal nucleus caudalis in rats. Brain Res. 656:1994;236-244.
21. 3 receptors. Brain Res. 663:1994;287-292.
22. 2 in rats. Brain Res. 749:1997;354-357.
23. Oka T., Oka K., Hosoi M., Aou S., Hori T. The opposing effects of interleukin-1β microinjected into the preoptic hypothalamus and the ventromedial hypothalamus on nociceptive behavior in rats. Brain Res. 700:1995;271-278.
24. 2-induced fever and changes in nociception in rats, 8th Naito Conference on Neuro-immuno-endocrine Networks III, 1996, p. 87.
25. Pitchford S., Levine J.D. Prostaglandins sensitize nociceptors in cell culture. Neurosci. Lett. 132:1991;105-108.
26. 2α in the rat. I. Behavioral, antinociceptive and anticonvulsant actions of intraventricular prostaglandins in the rat. Psychopharmacology. 50:1976;89-94.
27. 3 in the mouse nervous system. Neuroscience. 62:1994;919-928.
28. Taiwo Y.O., Levine J.D. Prostaglandins inhibit endogenous pain control mechanisms by blocking transmission at spinal noradrenergic synapses. J. Neurosci. 8:1988;1346-1349.
29. Taiwo Y.O., Levine J.D. Prostaglandin effects after elimination of indirect hyperalgesic mechanisms in the skin of the rat. Brain Res. 492:1989;397-399.
30. 2α to conscious mice. Brain Res. 510:1990;26-32.
31. Ushikubi F., Hirata M., Narumiya S. Molecular biology of prostanoid receptors; an overview. J. Lipid Mediators Cell Signal. 12:1995;343-359.