Effect of spinal cyclooxygenase inhibitors in rat using the formalin test and in vitro prostaglandin E2 release

European Journal of Pharmacology

Volumn 331, Issue 2-3, 1997, Pages 155-160

  Dirig, David M ^b   Konin, Gabrielle P ^a   Isakson, Peter C ^c   Yaksh, Tony L ^a,b  

^a University of California   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c PFIZER INC   (United States)

Author keywords

Cyclooxygenase; Formalin; In vitro; Intrathecal; Non steroidal anti inflammatory drugs; Prostaglandin E2; Release; Spinal cord

Indexed keywords

4 [5 (4 CHLOROPHENYL) 3 TRIFLUOROMETHYL 1H PYRAZOL 1 YL]BENZENESULFONAMIDE; 5 (4 FLUOROPHENYL) 1 [(4 METHYLSULFONYL)PHENYL] 3 TRIFLUOROMETHYLPYRAZOLE; FORMALDEHYDE; IBUPROFEN; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; INTRATHECAL DRUG ADMINISTRATION; MALE; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN RELEASE; RADIOIMMUNOASSAY; RAT; SPINAL CORD;

ANIMALS; CYCLOOXYGENASE INHIBITORS; DINOPROSTONE; ELECTRIC STIMULATION; FORMALDEHYDE; ISOENZYMES; MALE; PAIN MEASUREMENT; PERFUSION; POTASSIUM; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RADIOIMMUNOASSAY; RATS; RATS, SPRAGUE-DAWLEY; SPINAL CORD;

EID: 0030757530     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(97)01053-4     Document Type: Article

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