From agonist to antagonist: Fab fragments of an agonist-like monoclonal anti-β2-adrenoceptor antibody behave as antagonists

Molecular Pharmacology

Volumn 58, Issue 2, 2000, Pages 373-379

  Mijares, Alfredo ^a   Lebesgue, Diane ^b   Wallukat, Gerd ^c   Hoebeke, Johan ^d  

^a INSTITUTO VENEZOLANO DE INVESTIGACIONES CIENTÍFICAS   (Venezuela)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

^c MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^d INSTITUT DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ADRENERGIC RECEPTOR; CALCIUM CHANNEL; CALCIUM ION; CLENBUTEROL; IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN G; MONOCLONAL ANTIBODY;

ANIMAL CELL; ANTIBODY AFFINITY; ANTIGEN ANTIBODY REACTION; ARTICLE; CALCIUM CONDUCTANCE; CHRONOTROPISM; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DIMERIZATION; HEART CELL CULTURE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR INTRINSIC ACTIVITY; RECEPTOR SENSITIVITY; SIGNAL TRANSDUCTION;

EID: 0033916687     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.58.2.373     Document Type: Article

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