PSF is a novel corepressor that mediates its effect through Sin3A and the DNA binding domain of nuclear hormone receptors

Molecular and Cellular Biology

Volumn 21, Issue 7, 2001, Pages 2298-2311

  Mathur, M ^a   Tucker, P W ^a   Samuels, H H ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE ACETYLTRANSFERASE; HORMONE; HORMONE RECEPTOR; TRANSCRIPTION FACTOR;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; DISSOCIATION; DNA BINDING; GENE EXPRESSION REGULATION; GENE SILENCING; HELA CELL; HUMAN; HUMAN CELL; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; RECEPTOR BINDING;

ANIMALS; BINDING SITES; DNA-BINDING PROTEINS; HELA CELLS; HUMANS; MICE; PLASMIDS; PROTEIN BINDING; RECEPTORS, CYTOPLASMIC AND NUCLEAR; REPRESSOR PROTEINS; RNA SPLICING; RNA-BINDING PROTEINS; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0035106562     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.21.7.2298-2311.2001     Document Type: Article

References (92)

1. Human 100-kDa homologous DNA-pairing protein is the splicing factor PSF and promotes DNA strand invasion
2. AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer
3. The CBP co-activator is a histone acetyltransferase
4. nrb/NonO
5. The histone acetylase PCAF is a nuclear receptor coactivator
6. Cloning and characterization of RAP250, a novel nuclear receptor coactivator
7. Steroid receptor family: Structure and functions
8. Functional evidence for ligand-dependent dissociation of thyroid hormone and retinoic acid receptors from an inhibitory cellular factor
9. Role of CBP/P300 in nuclear receptor signalling
10. Identification of PSF, the polypyrimidine tract-binding protein-associated splicing factor, as a developmentally regulated neuronal protein
11. Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300
12. A transcriptional co-repressor that interacts with nuclear hormone receptors
13. Fusion of splicing factor genes PSF and NonO (p54nrb) to the TFE3 gene in papillary renal cell carcinoma
14. Protein encoded by v-erbA functions as a thyroid hormone receptor antagonist
15. Histone deacetylase associated with mSin3A mediates repression by the acute promyelocytic leukemia-associated PLZF protein
16. The embryonic enhancer-binding protein SSAP contains a novel DNA-binding domain which has homology to several RNA-binding proteins
17. The embryonic transcription factor stage specific activator protein contains a potent bipartite activation domain that interacts with several RNA polymerase II basal transcription factors
18. Interactions of thyroid hormone receptor with the human immunodeficiency virus type 1 (HIV-1) long terminal repeat and the HIV-1 Tat transactivator
19. KB and Sp1 DNA motifs of the human immunodeficiency virus type 1 long terminal repeat function as novel thyroid hormone response elements
20. Accurate transcription initiation by RNA polymerase II in soluble extract from isolated mammalian nuclei
21. Purification and cDNA cloning of HeLa cell p54nrb, a nuclear protein with two RNA recognition motifs and extensive homology to human splicing factor PSF and Drosophila NONA/BJ6
22. The retinoic acid receptor-β2 contains two separate cell-specific transactivation domains, at the N-terminus and in the ligand binding domain
23. Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex
24. Half-site spacing and orientation determines whether thyroid hormone and retinoic acid receptors and related factors bind to DNA response elements as monomers, homodimers, or heterodimers
25. pEXPRESS: A family of expression vectors containing a single transcription unit active in prokaryotes, eukaryotes and in vitro
26. Aberrant recruitment of the nuclear receptor corepressor-histone deacetylase complex by the acute myeloid leukemia fusion partner ETO
27. A novel set of spliceosome-associated proteins and the essential splicing factor PSF bind stably to pre-mRNA prior to catalytic step II of the splicing reaction
28. Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia
29. A dominant-negative peroxisome proliferator-activated receptor gamma (PPARgamma) mutant is a constitutive repressor and inhibits PPARgamma- mediated adipogenesis
30. p300 is a component of an estrogen receptor coactivator complex
31. A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression
32. GRIP1, a transcriptional coactivator for the AF-2 transactivation domain of steroid, thyroid, retinoid, and vitamin D receptors
33. GRIP1, a novel mouse protein that serves as a transcriptional coactivator in yeast for the hormone binding domains of steroid receptors
34. SMRT corepressor interacts with PLZF and with the PML-retinoic acid receptor alpha (RARalpha) and PLZF-RARalpha oncoproteins associated with acute promyelocytic leukemia
35. Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor
36. Nuclear receptor corepressors partner with class II histone deacetylases in a Sin3-independent repression pathway
37. Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators
38. The vitamin D receptor binds in a transcriptionally inactive form and without a defined polarity on a retinoic acid response element
39. A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors
40. Isolation of a novel histone deacetylase reveals that class I and class II deacetylases promote SMRT-mediated repression
41. Sin meets NuRD and other tails of repression
42. Thyroid hormone receptor-binding protein, an LXXLL motif-containing protein, functions as a general coactivator
43. Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression
44. A nuclear factor, ASC-2, is a cancer-amplified transcriptional coactivator essential for ligand-dependent transactivation by nuclear receptors in vivo
45. NRIF3 is a novel coactivator mediating functional specificity of nuclear hormone receptors
46. RAC3, a steroid/nuclear receptor-associated coactivator that is related to SRC-1 and TIF2
47. Role of the histone deacetylase complex in acute promyelocytic leukaemia
48. A mammalian activity required for the second step of pre-messenger RNA splicing
49. ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors
50. The snRNP-free U1A (SF-A) complex(es): Identification of the largest subunit as PSF, the polypyrimidine-tract binding protein-associated splicing factor
51. A new family of nuclear receptor coregulators that integrate nuclear receptor signaling through CREB-binding protein
52. Nuclear receptor coregulators: Cellular and molecular biology
53. Differential nuclear localization and nuclear matrix association of the splicing factors PSF and PTB
54. Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase
55. The RRM domain of MINT, a novel Msx2 binding protein, recognizes and regulates the rat osteocalcin promoter
56. The transcriptional coactivators p300 and CBP are histone acetyltransferases
57. Sequence and characterization of a coactivator of the steroid hormone receptor superfamily
58. Cloning and characterization of PSF, a novel pre-mRNA splicing factor
59. TLS (translocated-in-liposarcoma) is a high-affinity interactor for steroid, thyroid hormone, and retinoid receptors
60. A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
61. The ligand binding domains of the thyroid hormone/retinoid receptor gene subfamily function in vivo to mediate heterodimerization, gene silencing, and transactivation
62. Constitutive activation of gene expression by thyroid hormone receptor results from reversal of p53-mediated repression
63. Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex
64. A novel protein complex that interacts with the vitamin D3 receptor in a ligand-dependent manner and enhances VDR transactivation in a cell-free system
65. GAL4-VP16 is an unusually potent transcriptional activator
66. A vector for expressing GAL4(1-147) fusions in mammalian cells
67. Identification of TRACs (T3 receptor-associating cofactors), a family of cofactors that associate with, and modulate the activity of, nuclear hormone receptors
68. Activation and repression by nuclear hormone receptors: Hormone modulate an equilibrium between active and repressive states
69. Steroid receptor coactivator-1 is a histone acetyltransferase
70. n-Butyrate effects thyroid hormone stimulation of prolactin production and mRNA levels in GH1 cells
71. The RNA-splicing factor PSF/p54 controls DNA-topoisomerase I activity by a direct interaction
72. nrb stimulates "jumping" of DNA topoisomerase I between separate DNA helices
73. The interaction of the vitamin D receptor with nuclear receptor corepressors and coactivators
74. TRAM-1, a novel 160-kDa thyroid hormone receptor activator molecule, exhibits distinct properties from steroid receptor coactivator-1
75. Differential inhibition of signaling pathways by dominant-negative SH2/SH3 adapter proteins
76. Myotonic dystrophy: The role of the CUG triplet repeats in splicing of a novel DMPK exon and altered cytoplasmic DMPK mRNA isoform ratios
77. The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function
78. Polypyrimidine tract-binding protein-associated splicing factor is a negative regulator of transcriptional activity of the porcine p450scc insulin-like growth factor response element
79. TIF2, a 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptors
80. The C, elegans Mi-2 chromatin-remodelling proteins function in vulval cell fate determination
81. Transcriptional repression in Saccharomyces cerevisiae by a SIN3-LexA fusion protein
82. The histone deacetylase-3 complex contains nuclear receptor corepressors
83. Transcriptional repression by the SMRT-mSin3 corepressor: Multiple interactions, multiple mechanisms, and a potential role for TFIIB
84. A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A
85. NonO, a non-POU-domain-containing, octamer-binding protein, is the mammalian homolog of Drosophila nonAdiss
86. NonO enhances the association of many DNA-binding proteins to their targets
87. Modulation of the transcriptional activity of thyroid hormone receptors by the tumor suppressor p53
88. Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells
89. Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A
90. Cloning and characterization of a corepressor and potential component of the nuclear hormone receptor repression complex
91. Purification and characterization of a DNA-binding heterodimer of 52 and 100 kDa from HeLa cells
92. Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation