The snRNP-free U1A (SF-A) complex(es): Identification of the largest subunit as PSF, the polypyrimidine-tract binding protein-associated splicing factor

RNA

Volumn 4, Issue 12, 1998, Pages 1493-1499

  Lutz, Carol S ^a,b   Cooke, Charles ^a   O'Connor, J Patrick ^b   Kobayashi, Ryuji ^c   Alwine, James C ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^c Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

Author keywords

Polyadenylation; RNA processing; SF A complex; SnRNP free U1A (SF A); Splicing; U1snRNP

Indexed keywords

BINDING PROTEIN; PROTEIN SUBUNIT; PYRIMIDINE DERIVATIVE;

ARTICLE; COMPLEX FORMATION; EXON; IMMUNOPRECIPITATION; MESSENGER RNA SYNTHESIS; NONHUMAN; POLYADENYLATION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RNA CLEAVAGE; RNA PROCESSING; RNA SPLICING; SUCROSE GRADIENT;

AMINO ACID SEQUENCE; CENTRIFUGATION, DENSITY GRADIENT; GLUTATHIONE TRANSFERASE; MOLECULAR SEQUENCE DATA; POLY A; PRECIPITIN TESTS; PROTEIN BINDING; RECOMBINANT FUSION PROTEINS; RIBONUCLEOPROTEIN, U1 SMALL NUCLEAR; RNA SPLICING; RNA-BINDING PROTEINS;

EID: 0031760528     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: 10.1017/S1355838298981183     Document Type: Article

References (27)

1. Baserga SJ, Steitz JA. 1993. The diverse world of small ribonucleoproteins. In: Gesteland RF, Atkins JF, eds., The RNA world. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press. pp 359-382.
2. Bennett M, Michaud S, Kingston J, Reed R. 1992. Protein components specifically associated with prespliceosome and spliceosome complexes. Genes & Dev 6:1986-2000.
3. Berget SM. 1995. Exon recognition in vertebrate splicing. J Biol Chem 270:2411-2414.
4. Boelens WC, Jansen EJR, van Venrooij WJ, Stripeke R, Mattaj IW, Gunderson SI. 1993. The human U1A snRNP-specific protein inhibits polyadenylation of its own pre-mRNA. Cell 72:881-892.
5. Chiou HC, Dabrowski C, Alwine JC. 1991. Simian virus 40 late mRNA leader sequences involved in augmenting mRNA accumulation via multiple mechanisms, including increased polyadenylation efficiency. J Virol 65:6677-6685.
6. Colgan DF, Manley JL. 1997. Mechanism and regulation of mRNA polyadenylation. Genes & Dev 11:2755-2766.
7. Gozani O, Patton JG, Reed R. 1994. A novel set of spliceosome-associated proteins and the essential splicing factor PSF bind stably to pre-mRNA prior to catalytic step II of the splicing reaction. EMBO J 13:3356-3367.
8. Gruda MC, Zabolotny JM, Xiao JH, Davidson I, Alwine JC. 1993. Transcriptional activation by SV40 T antigen: Interactions with multiple components of the transcriptional complex. Mol Cell Biol 13:961-969.
9. Gunderson SI, Beyer K, Martin G, Keller W, Boelens WC, Mattaj IW. 1994. The human U1A snRNP protein regulates polyadenylation via a direct interaction with poly(A) polymerase. Cell 76:531-541.
10. Gunderson SI, Vagner S, Polycarpou-Schwarz M, Mattaj IW. 1997. Involvement of the carboxyl terminus of vertebrate poly(A) polymerase in U1A autoregulation and in the coupling of splicing and polyadenylation. Genes & Dev 11:761-773.
11. Harlow E, Lane D, eds. 1988. Antibodies: A laboratory manual. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press.
12. Jessen TH, Oubridge C, Teo CH, Pritchard C, Nagai K. 1991. Identification of molecular contacts between the U1A small nuclear ribonucleoprotein and U1 RNA. EMBO J 10:3447-3456.
13. Lindsey LA, Crow AJ, Garcia-Blanco MA. 1995. A mammalian activity required for the second step of pre-messenger RNA splicing. J Biol Chem 270:13415-13421.
14. Lutz CS, Alwine JC. 1994. Direct interaction of the U1snRNP-A protein with the upstream efficiency element of the SV40 late polyadenylation signal. Genes & Dev 8:576-586.
15. Lutz CS, Murthy KGK, Schek N, O'Connor JP, Manley JL, Alwine JC. 1996. Interaction between the U1snRNP-A protein and the 160-kD subunit of cleavage-polyadenylation specificity factor increases polyadenylation efficiency in vitro. Genes & Dev 10:325-337.
16. Lutz-Freyermuth C, Query CC, Keene JD. 1990. Quantitative determination that one of two potential RNA-binding domains of the A protein component of the U1 small nuclear ribonucleoprotein complex binds with high affinity to stem-loop II of U1 RNA. Proc Natl Acad Sci USA 87:6393-6397.
17. Moore CL, Sharp PA. 1985. Accurate cleavage and polyadenylation of exogenous RNA substrate. Cell 41:845-855.
18. Moore MJ, Query CC, Sharp PA. 1993. Splicing of precursors to messenger RNA by the spliceosome. In: Gesteland RF, Atkins JF, eds. The RNA world. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press, pp 303-358.
19. Nesic D, Cheng J, Maquat LE. 1993. Sequences within the last intron function in RNA 3' end formation in cultured cells. Mol Cell Biol 13:3359-3369.
20. Nesic D, Maquat LE. 1994. Upstream introns influence the efficiency of final intron removal and RNA 3′ end formation. Genes & Dev 8:363-375.
21. Niwa M, Berget SM. 1991. Mutation of the AAUAAA polyadenylation signal depresses in vitro splicing of proximal but not distal introns. Genes & Dev 5:2086-2095.
22. Niwa M, Rose SD, Berget SM. 1990. In vitro polyadenylation is stimulated by the presence of an upstream intron. Genes & Dev 4:1552-1559.
23. O'Connor JP, Alwine JC, Lutz CS. 1997. Identification of a novel, non-snRNP protein complex containing U1A protein. RNA 3:1444-1455.
24. Patton JG, Porro EB, Galceran J, Tempst P, Nadal-Ginard B. 1993. Cloning and characterization of PSF, a novel pre-mRNA splicing factor. Genes & Dev 7:393-406.
25. Proudfoot, N. 1996. Ending the message is not so simple. Cell 87:779-781.
26. Staley JP, Guthrie C. 1998. Mechanical devices of the spliceosome: Motors, clocks, springs, and things. Cell 92:315-326.
27. Wahle E, Keller W. 1996. The biochemistry of polyadenylation. TIBS 21:247-251.