The intracisternal A-particle proximal enhancer-binding protein activates transcription and is identical to the RNA- and DNA-binding protein p54(nrb)/NonO

Molecular and Cellular Biology

Volumn 17, Issue 2, 1997, Pages 677-686

  Basu, Amitabha ^a   Dong, Benhao ^b,c   Krainer, Adrian R ^b   Howe, Chin C ^a  

^a WISTAR INSTITUTE   (United States)

^b Watson School of Biological Sciences   (United States)

^c NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CARCINOMA CELL; EMBRYO; ENHANCER REGION; HELA CELL; LONG TERMINAL REPEAT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; REPORTER GENE; RNA SPLICING; TRANSACTIVATION;

EID: 0031039425     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.17.2.677     Document Type: Article

References (40)

1. Aebersold, R. H., J. Leavitt, R. A. Saavedra, L. E. Hood, and S. B. H. Kent. 1987. Internal amino acid sequence analysis of proteins separated by one-or two-dimensional gel electrophoresis after in situ protease digestion on nitrocellulose. Proc. Natl. Acad. Sci. USA 84:6970-6974.
2. Ausubel, F. M., R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl (ed.). 1990. Current protocols in molecular biology, p. 10.81-10.86. Green Publishing Associates and Wiley Interscience, John Wiley and Sons, New York, N.Y.
3. Birney, E., S. Kumar, and A. R. Krainer. 1993. Analysis of the RNA-recognition motif and RS and RGG domains: conservation in metazoan pre-mRNA splicing factors. Nucleic Acids Res. 21:5803-5816.
4. Burd, C. G., and G. Dreyfuss. 1994. Conserved structures and diversity of functions of RNA binding proteins. Science 265:615-621.
5. Burd, C. G., and G. Dreyfuss. 1994. RNA binding specificity of hnRNP A1: significance of hnRNP A1 high-affinity binding sites in pre-mRNA splicing. EMBO J. 13:1197-1204.
6. Champlin, D. T., and J. T. Lis. 1994. Distribution of B52 within a chromosomal locus depends on the level of transcription. Mol. Biol. Cell 5:71-79.
7. Chang-Yeh, A., D. E. Mold, and R. C. C. Huang. 1991. Identification of a novel murine IAP-promoted placenta-expressed gene. Nucleic Acids Res. 19:3667-3672.
8. Christy, R. J., and R. C. C. Huang. 1988. Functional analysis of the long terminal repeats of intracisternal A-particle genes: sequences within the U3 region determine both the efficiency and direction of promoter activity. Mol. Cell. Biol. 8:1093-1102.
9. DeAngelo, D. J., J. Defalco, L. Rybacki, and G. Childs. 1995. The embryonic enhancer-binding protein SSAP contains a novel DNA-binding domain which has homology to several RNA-binding proteins. Mol. Cell. Biol. 15: 1254-1264.
10. nrb, a nuclear protein with two RNA recognition motifs and extensive homology to human splicing factor PSF and Drosophila NonA/Bj6. Nucleic Acids Res. 21:4085-4092.
11. Ellis, L., E. Clauser, D. O. Morgan, M. Edery, R. A. Roth, and W. J. Rutter. 1986. Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose. Cell 45:721-732.
12. Engelbrecht, J., S. Knudsen, and S. Brunak. 1992. G+C-rich tract in 5′ end of human introns. J. Mol. Biol. 227:108-113.
13. Falzon, M., and E. L. Kuff. 1989. Isolation and characterization of a protein fraction that binds to enhancer core sequences in intracisternal A-particle long terminal repeats. J. Biol. Chem. 264:21915-21922.
14. Falzon, M., and E. L. Kuff. 1991. Binding of the transcription factor EBP-80 mediates the methylation response of an intracisternal A-particle long terminal repeat promoter. Mol. Cell. Biol. 11:117-125.
15. Gozani, O., J. G. Patton, and R. Reed. 1994. A novel set of spliceosome-associated proteins and the essential splicing factor PSF bind stably to pre-mRNAa prior to catalytic step II of the splicing reaction. EMBO J. 13:3356-3367.
16. Hager, D. A., and R. R. Burgess. 1980. Elution of proteins from sodium dodecyl sulfate-polyacrylamide gels, removal of sodium dodecyl sulfate, and renaturation of enzymatic activity: results with sigma subunit of Escherichia coli RNA polymerase, wheat germ DNA topoisomerase, and other enzymes. Anal. Biochem. 109:76-86.
17. nrb. J. Biol. Chem. 271:11171-11181.
18. Howe, C. C., and G. C. Overton. 1986. Expression of an intracisternal A particle is elevated during differentiation of embryonal carcinoma cells. Mol. Cell. Biol. 6:150-157.
19. Kamat, J. P., A. Basu, K. Satyamoorthy, L. Showe, and C. C. Howe. 1995. IPEB transcription factor regulating the intracisternal A particle gene during F9 cell differentiation is expressed at sites of lymphoid development. Mol. Reprod. Dev. 41:8-15.
20. Krainer, A. R., T. Maniatis, B. Ruskin, and M. R. Green. 1984. Normal and mutant human β-globin pre-mRNAs are accurately and efficiently spliced in vitro. Cell 36:993-1005.
21. Kuff, E. L. 1990. Intracisternal particle in mouse neoplasia. Cancer Cells 2:398-400.
22. Kuff, E. L., and K. K. Lueders. 1988. The intracisternal A particle gene family: structural and functional aspects. Adv. Cancer Res. 51:183-276.
23. Lamb, B. T., K. Satyamoorthy, L. Li, D. Solter, and C. C. Howe. 1991. CpG methylation of an endogenous retroviral enhancer inhibits transcription factor binding and activity. Gene Expression 1:185-196.
24. Lamb, B. T., K. Satyamoorthy, D. Solter, A. Basu, M. Q. Xu, R. Weinmann, and C. C. Howe. 1992. A DNA element that regulates expression of an endogenous retrovirus during F9 cell differentiation is E1A dependent. Mol. Cell. Biol. 12:4824-4833.
25. Leslie, K. B., F. Lee, and J. W. Schrader. 1991. Intracisternal A-type particle-mediated activations of cytokine genes in a murine myelomonocytic leukemia: generation of functional cytokine mRNAs by retroviral splicing events. Mol. Cell. Biol. 11:5562-5570.
26. Lueders, K. K., J. W. Fewell, E. L. Kuff, and T. Koch. 1984. The long terminal repeat of an endogenous intracisternal A-particle gene functions as a promoter when introduced into eukaryotic cells by transfection. Mol. Cell. Biol. 4:2128-2135.
27. Meitz, J. A., J. W. Fewell, and E. L. Kuff. 1992. Selective activation of a discrete family of endogenous proviral elements in normal BALB/c lymphocytes. Mol. Cell. Biol. 12:220-228.
28. Nussinov, R. 1989. Conserved signals around the 5′ splice sites in eukaryotic nuclear precursor mRNAs: G-runs the frequent in the introns and C-in the exons near both 5′ and 3′ splice sites. J. Biomol. Struct. Dyn. 6:985-1000.
29. O'Keefe, R. T., A. Mayeda, C. L. Sadowski, and A. R. Krainer. 1994. Disruption of pre-mRNA splicing in vivo results in reorganization of splicing factors. J. Cell Biol. 124:249-260.
30. Patton, J. G., E. B. Porro, J. Galceran, P. Tempst, and B. Nadal-Ginard. 1993. Cloning and characterization of PSF, a novel pre-mRNA splicing factor. Genes Dev. 7:393-406.
31. Sadowski, I., and M. Ptashne. 1989. A vector expressing Ga14(1-147) fusion in mammalian cells. Nucleic Acids Res. 17:7539.
32. Satyamoorthy, K., K. Park, M. L. Atchison, and C. C. Howe. 1993. The intracisternal A-partiele upstream element interacts with transcription factor YY1 to activate transcription: pleiotropic effects of YY1 on distinct DNA promoter elements. Mol. Cell. Biol. 13:6621-6628.
33. Schindelin, H., M. A. Marahiel, and U. Heinemann. 1993. Universal nucleic acid-binding domain revealed by crystal structure of the B. subtilis major cold-shock protein. Nature (London) 364:164-168.
34. Sirand-Pugnet, P., P. Durosay, E. Brody, and J. Marie. 1995. An intronic (A/U)GGG repeat enhances the splicing of an alternative intron of the chicken beta-tropomyosin pre-mRNA. Nucleic Acids Res. 23:3501-3507.
35. Spector, D. L. 1993. Macromolecular domains within the cell nucleus. Annu. Rev. Cell Biol. 9:265-315.
36. Tsai, D. E., D. S. Harper, and J. D. Keene. 1991. U1-snRNP-A protein selects a ten nucleotide consensus sequence from a degenerate RNA pool presented in various structural contexts. Nucleic Acids Res. 19:4931-4936.
37. Xing, Y., C. V. Johnson, P. R. Dobner, and J. B. Lawrence. 1993. Higher level organization of individual gene transcription and RNA splicing. Science 259:1326-1330.
38. diss. Mol. Cell. Biol. 13:5593-5603.
39. Zhang, G., K. L. Taneja, R. H. Singer, and M. R. Green. 1994. Localization of pre-mRNA splicing in mammalian nuclei. Nature (London) 372:809-812.
40. Zierler, M., R. J. Christy, and R. C. C. Huang. 1992. Nuclear protein binding to the 5′ enhancer region of the intracisternal A particle long terminal repeat. J. Biol. Chem. 267:21200-21206.