A regulatory role for cytoplasmic YVKM motif in CTLA-4 inhibition of TCR signaling

European Journal of Immunology

Volumn 31, Issue 7, 2001, Pages 2042-2050

  Schneider, Helga ^a   Dias, Silvy Da Rocha ^c   Hu, I ^b   Rudd, Christopher E ^a,c  

^a IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

^b DANA FARBER CANCER INSTITUTE   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

AP 2; CTLA 4; Phosphatidylinositol 3 kinase; T cell signaling; YVKM motif

Indexed keywords

ADAPTOR PROTEIN; ADAPTOR PROTEIN 1; ADAPTOR PROTEIN 2; CD28 ANTIGEN; CLATHRIN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; MONOCLONAL ANTIBODY; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE ZAP 70; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE PHOSPHATASE SHP 2; RECEPTOR SUBUNIT; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; LIGATION; MOLECULAR BIOLOGY; MOUSE; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; SOLUBILITY;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AMINO ACID MOTIFS; ANIMALS; ANTIBODIES; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION; CYTOPLASM; HYBRIDOMAS; IMMUNOCONJUGATES; INTERLEUKIN-2; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MICE; PROTEIN-TYROSINE KINASES; PROTEIN-TYROSINE-PHOSPHATASE; RECEPTOR-CD3 COMPLEX, ANTIGEN, T-CELL; RECEPTORS, ANTIGEN, T-CELL; SHP1 PROTEIN TYROSINE PHOSPHATASE; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; ZAP-70 PROTEIN-TYROSINE KINASE;

EID: 0034946788     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200107)31:7<2042::AID-IMMU2042>3.0.CO;2-D     Document Type: Article

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